• Title/Summary/Keyword: postmenopausal

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Raloxifene and Lipid Profiles in Postmenopausal Women: A Systematic Review (폐경기 여성의 랄록시펜과 혈중 지질에 관한 체계적 문헌고찰)

  • Yoo, Ji-Soo;An, Ji-Hyoun;Kim, Doo-Ree;Chu, Sang-Hui
    • Journal of Korean Biological Nursing Science
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    • v.12 no.1
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    • pp.63-72
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    • 2010
  • Purpose: The purpose of this study is to assess the effects of raloxifene in prevention of cardiovascular disease in postmenopausal women. Methods: A systematic literature review was conducted. Data sources: The existing literature from 1986 to 2009 was searched electronically using the data base of Medline with the key words of hypertension, obesity, diabetes, cholesterol, lipid, myocardial infarction, coronary events with combination of raloxifene. Study selection: The criteria for inclusion in the review were 1) an randomized clinical trial (RCT), 2) postmenopausal women, 3) English or Korean language. Finally, 15 articles were included in the review. Data extraction: Findings from the studies were organized according to the results of lipid profile changes by two authors. Results: Among 15 articles, 12 studies reported the beneficial effects of raloxifene on LDL cholesterol and 9 studies on total cholesterol in the postmenopausal women. Conclusion: The consistent results on reduction of LDL cholesterol and total cholesterol in raloxifene using postmenopausal women were confirmed. However, the effect of raloxifene on other components of lipid profile and endothelial function were still remaining controversial.

The Analysis of the Factors Related to Diet Quality in the Postmenopausal Women (폐경 후 여성의 식사의 질과 관련 요인 분석)

  • 최윤정;김상연;정경아;장유경
    • Journal of Nutrition and Health
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    • v.35 no.1
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    • pp.102-114
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    • 2002
  • This study was performed to assess the relationship between diet quality and general characteristics, stress, exercise habits, and nutritional knowledge score in the postmenopausal women. The data of dietary intakes were obtained using food frequency questionnaires which were collected from 151 postmenopausal women in urban area. Diet quality was assessed by INQ(index of nutritional quality), MAR(mean adequacy ratio), DDS(dietary diversity score), DVS(dietrary variety score), DQI(diet quality index). The results are summarized as follows. The mean age of the subjects was 59.9 years old. The means of height, weight, and BMI were 154.7cm, 57.2kg and 23.9 respectively. The subjects who did not exercise regularly were 70.9% and those who excercised at least once a week were 29.1%. The subjects who had regular meal time were 69.5% and those who ate breakfast regularly were 72.6%. More than 2/3 of subjects had regular eating behavior. Overall dict quality was significantly(p < 0.05) associated with INQ, MAR, DDS, DQI. However, there was no significant association between income level and diet quality. In conclusion, it would be beneficial to provide nutritional education included dietary diversity, dietary variety, dietary guideline, and adequate flood amount, to prevent chronic degenerative disease and maintain healthful life in the postmenopausal women.

Evaluation of Endometrial Precancerous Lesions in Postmenopausal Obese Women - A High Risk Group?

  • Acmaz, Gokhan;Aksoy, Huseyin;Albayrak, Evrim;Baser, Muruvet;Ozyurt, Sezin;Aksoy, Ulku;Unal, Dilek
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.195-198
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    • 2014
  • Aim: To evaluate precancerous lesions such as hyperplasia and endometrial polyps in obese postmenopausal women. Materials and Methods: Women who were referred with abnormal uterine bleeding in postmenopausal period or the presence of endometrial cells on cervical cytology in our department were investigated. Anthropometric measurements such as height, weight, body mass index, waist/hip ratio and endometrial thickness were compared between a precancerous lesion (hyperplasia and endometrial polyp) group and a pathologically normal group. Results: We detected statistically significant thickening of endometrium in patients with precancerous lesions. Moreover patients with precancerous lesions had higher body mass index than the pathologically normal group. Conclusions: We found elevated precancerous lesion rates in overweight and obese women in the postmenopausal period, of interest given that the prevalence of obesity is increasing in most parts of the world. Although screening for endometrial cancer is not recommended for the general population, in high-risk populations like obese postmenopausal women, it may be very important.

Fall Risk related Factors in Postmenopausal Women (폐경여성의 낙상 위험과 관련요인)

  • Lee, Jung-Han;Kim, Hee Seung
    • Korean Journal of Adult Nursing
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    • v.26 no.5
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    • pp.533-542
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    • 2014
  • Purpose: The purpose of this study was to understand the risk of falling associated with postmenopausal women and to identify the relationships between this risk and factors such as lifestyle, metabolic syndrome, and bone mineral density. Methods: The sample was 128 postmenopausal women between 50 and 65 from one menopausal clinic in an urban city. The Risk Assessment for Falls Scale II, developed by Glydenvand and Reinboth (1982) and adapted by Park Young-Hye (2003), was modified and used for this study. Results: The average fall-risk score in postmenopausal women was 7.2 out of 33, the fall-risk score associated with lifestyle was higher in women exposed to stress frequently or who favored spicy or salty foods. The fall-risk score associated with metabolic syndrome was higher in groups with HBP or with a waist circumference of 80cm or greater. The fall-risk score in groups with three or more factors of metabolic syndrome was the highest. Conclusion: The risk of fall in post-menopausal women was higher in groups with only elementary education, unemployed, reported two or more chronic diseases or reported frequent exposure to stress and for women who preferred spicy or salty foods or exhibited three or more factors of metabolic syndrome.

Effects of Lifestyle Modification Program on Body Composition, Metabolic Syndrome Markers, and Depression in Obese Postmenopausal Women (생활양식 개선프로그램이 폐경후 비만여성의 신체조성, 대사성증후군 지표 및 우울에 미치는 효과)

  • Park, Nam Hee
    • Journal of Korean Public Health Nursing
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    • v.27 no.2
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    • pp.313-326
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    • 2013
  • Purpose: The aim of this study was to evaluate the effects of lifestyle modification program on body composition and metabolic syndrome makers, depression in obese postmenopausal women. Method: The research design of this study included a non-equivalent control group pretest-posttest design. The lifestyle modification program was administered twice a week for 12 weeks the experimental group, whereas the control group had no program. The experimental group consisted of 22 obese postmenopausal women while the control group contained 19 subjects. The study also attempted to measure the effects of the program on body composition, metabolic syndrome markers, and depression in obese postmenopausal women. The data were analyzed by descriptive statistics and a t-test using the SPSS/WIN 17.0 program. Results: After participating in the lifestyle modification program, the experimental group showed statistically significant decreases in systolic pressure, diastolic pressure and depression, but no change in body composition. Conclusions: The result of this study show that the lifestyle modification program had a significant impact on obese postmenopausal women. In the future, it is necessary to offer more tailed program for a longer period.

A Comparison Study on Nutrients, Phytoestrogens and Food Intakes of Postmenopausal Women according to the Climacteric Symptom (폐경 여성의 갱년기 증상에 따른 영양소, 식물성 에스트로겐 및 식품 종류별 섭취 비교)

  • Kim, Mi-Hyun;Bae, Yun-Jung
    • Journal of the East Asian Society of Dietary Life
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    • v.16 no.5
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    • pp.533-541
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    • 2006
  • The purpose of this study was to investigate the relation between climacteric symptoms and intakes of various nutrients, phytoestrogens and foods in postmenopausal women. We conducted anthropometric measurements, questionnaire interview and 24hr dietary recall for 3 days in 128 postmenopausal women aged $49{\sim}64$. The subjects were divided into the two groups, NCMS(non climacteric symptoms group) and CMS(climacteric symptoms group), according to the severity of the climacteric symptoms. There were no significant difference in anthropometric measurements, maternal factors(menarche age, menopause age), subjective health status, frequency of exercise, smoking and drinking status between the two groups. The Mg and lignan precusor intakes of the NCMS group were significantly higher than those of the CMS group. Mg, lignan precusor, pulse and seed intakes had negative correlations with the severity of climacteric symptoms. From this study results, Mg, phytoestrogen(especially some lignan) and some food groups like as pulse and seeds may prevent and reduce climacteric symptoms in postmenopausal women.

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Effect of Vitamin D on Muscular Strength in Postmenopausal Women: A Meta-Analysis (비타민D 보충 요법이 폐경 후 여성 근력에 미치는 효과: 메타분석)

  • Kang, Purum;Kim, Jeehyoung;Kim, Myung Jin
    • Journal of Korean Biological Nursing Science
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    • v.21 no.4
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    • pp.239-248
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    • 2019
  • Purpose: Postmenopausal women are a unique population with high risk for the degeneration of muscle. The aim of the present meta-analysis was to accurately evaluate the effects of vitamin D on muscular strength in postmenopausal women. Methods: A review was conducted using electronic databases, including PubMed, EMBASE, Ovid Medline, CINAHL complete, and the Cochrane Library from inception through 19 March 2019. Included studies were selected by two independent reviewers. The meta-analysis were performed using Review Manager 5.3 software. Results: A total of nine randomized controlled clinical trials were included in this review. Vitamin D interventions led to no changes in the upper limb muscle strength (mean difference -0.16, 95% CI: -1.09 to 0.77), lower body muscle strength (standard mean difference 0.08, 95% CI: -0.11 to 0.26), and back/hip muscle strength (standard mean difference 0.06, 95% CI: -0.05 to 0.17). Conclusion: Pooled results from eight studies indicated that supplementation of vitamin D did not increase muscle strength in postmenopausal women. Apparently, the present review suggests that supplementation of vitamin D alone had no didn't show any beneficial effects on muscle strength in postmenopausal women.

Effects of physical activity and depression on oral health behavior and awareness symptoms in postmenopausal women (폐경여성의 신체활동과 우울이 구강건강행위 및 자각증상에 미치는 영향)

  • Park, Sin-Young;Lim, Sun-A
    • Journal of Korean society of Dental Hygiene
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    • v.21 no.5
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    • pp.595-600
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    • 2021
  • Objectives: For postmenopausal women who participated in the 2019 National Health and Nutrition Examination Survey, we aimed to provide basic data for oral health management interventions and oral policies for each life cycle of postmenopausal women by identifying the relationship between physical activity and depression on oral health behavior and awareness symptoms. Methods: The participants of this study were 1,628 menopausal women, and their general characteristics, physical activity, depression, and oral health behavior and awareness symptoms were investigated. This study used the complex sample frequency analysis, complex sample 𝞆2 test, and logistic regression analysis method, which is a sample design of the National Health and Nutrition Examination Survey. Results: The factors influencing physical activity were the use of oral hygiene device and chewing difficulty. and the influencing factors of depression experience were pain and chewing difficulty. Conclusions: As a result, physical activity and depression experience should be utilized by developing and oral health program for the promotion of oral health in postmenopausal women.

Association between dietary omega-3 fatty acid intake and depression in postmenopausal women

  • Chae, Minjeong;Park, Kyong
    • Nutrition Research and Practice
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    • v.15 no.4
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    • pp.468-478
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    • 2021
  • BACKGROUND/OBJECTIVES: This study aimed to analyze the association between dietary omega-3 fatty acid intake and depression in postmenopausal women using data from the Korea National Health and Nutrition Examination Survey (KNHANES) VI. SUBJECTS/METHODS: The KNHANES is a cross-sectional nationwide health and nutrition survey. Dietary data, including omega-3 fatty acids, were assessed using the 24-h recall method. Depression was evaluated using a survey questionnaire. The association between dietary omega-3 fatty acids and depression was evaluated using multivariate logistic regression analysis. Depression, according to the dietary omega-3 fatty acid intake, was expressed as the odds ratio (OR) with a 95% confidence interval (CI). A total of 4,150 postmenopausal women were included in the analysis. RESULTS: In the fully-adjusted model, the group with the highest dietary omega-3 fatty acid intake significantly showed lower prevalence of depression than the group with the lowest intake (OR, 0.52; 95% CI, 0.33-0.83); a significant linear trend was detected (P for trend = 0.04). According to the dose-response analysis using cubic restricted spline regression, this association was linear and monotonic (P for non-linearity = 0.32). CONCLUSIONS: In this study, the dietary omega-3 fatty acid intake in postmenopausal women was inversely proportional to depression in a dose-response manner. Large cohort studies are needed to verify the causality between omega-3 fatty acids and depression in Korean postmenopausal women.

A Study on the Clinical Study of Herbal Medicine for Postmenopausal Osteoporosis (폐경기 골다공증에 대한 한약 임상 연구 고찰)

  • Young-Eun Kim;Hee-Yoon Lee;Jang-Kyung Park;Young-Jin Yoon
    • The Journal of Korean Obstetrics and Gynecology
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    • v.36 no.3
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    • pp.129-153
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    • 2023
  • Objectives: The purpose of this study is to report the clinical effectiveness and safety of herbal medicine treatment for postmenopausal osteoporosis. Methods: Researchers searched papers through 5 online databases including The Cochrane Library Central, Pubmed, China Academic Journal (CAJ), Oriental medicine Advanced Searching Integrated System (OASIS) and Korean studies Information Service System (KISS). Randomized controlled trials (RCTs) that used herbal medicine as treatment were included. Results: Twenty three studies were selected by the selection and exclusion criteria. The treatment group was treated with herbal medicine alone or with herbal medicine and conventional medicine. The control group was treated with conventional medicine. Most common evaluation index was Bone Mineral Density (BMD) followed by total efficacy rate and level of bone metabolism markers, level of sex hormones, etc. Compared with the control group, the treatment group was more effective and safer in all of 23 studies. Conclusions: Herbal treatment alone could be an effective and safe option in treating postmenopausal osteoporosis. Moreover herbal treatment with conventional medicine could improve its therapeutic effect on postmenopausal osteoporosis as well.