• The Korean Journal of Nuclear Medicine Technology
• /
• v.14 no.2
• /
• pp.60-64
• /
• 2010

Purpose: Until now the general study for breast cancer patient has been mammography, breast sonography for anatomic diagnostics and $^{18}F$-FDG whole body PET for functional one. But the PEM (Positron Emission Mammography) was developed to increase sensitivity, specificity and accuracy to improve the disadvantage of each study. Therefore this present study aims to describe availability of PEM for improving diagnosis of breast cancer. Materials and Methods: During 3 months from January in 2010, PEM was performed on 100 patients who had history of breast cancer. Using Naviscan's PEM Flex Solo II scanner, PEM images of breast were acquired. And then we evaluated sensitivity, specificity and accuracy of PEM data by comparing results of PEM images with postoperative pathologic finding. Results: On the 100 patients, it could reveal 89 true positive, 9 false positive, 7 false negative and 87 true negative. Thus the results of sensitivity, specificity and accuracy for PEM was evaluated 92.7%, 90.6% and 91.7%. Conclusion: The sensitivity, specificity and accuracy have been reported 83.7%, 68.5% and 77.1% in mammography, and that was 89.1%, 79.1% and 83.4% in breast sonography. However the results of PEM were more increased than others. Therefore the results of this study will be available that PEM used diagnosis with breast cancer, used preoperative operation plan and helps to discovery of a part recurrence.

• Journal of Biomedical Engineering Research
• /
• v.31 no.4
• /
• pp.259-268
• /
• 2010

Breast cancer is the most prevalent woman cancer, and its prevalence rate is increasing rapidly. It is necessary to develop the breast-dedicated positron emission tomography (PET) or positron emission mammography (PEM) systems with high resolution and sensitivity to improve the accuracy of diagnosis of breast cancer. Therefore, it is necessary to develop the high-end PET system technologies, such as the measurement of depth-of-interaction (DOI) and fully digitalized data acquisition, to establish high performance breast imaging systems. In this paper, recent technical advances in breast-dedicated PET imaging systems will be reviewed.