• 한국전자통신학회논문지
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• 제7권4호
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• pp.917-924
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• 2012

본 연구는 우리나라 19세 이상 성인의 흡연 상태와 치주질환 위험도와의 관련성을 분석하여 흡연이 치주질환에 미치는 영향을 파악하고자 시도되었다. 연구결과에서 전체 대상자의 CPI 평균은 1.92이었고, 전체 대상자 6989명 중 CPI가 0-2인 그룹은 4707명(67.3%), 3-4인 그룹은 2282명(32.7%)이었다. 혼란변수를 보정하지 않았을 때 CPI가 3 이상인 그룹에서는 전혀 흡연을 하지 않는 그룹에 비해 과거 흡연을 한 그룹에서의 치주질환의 유병율에 대한 위험도는 1.78배(95% CI:1.56-2.02), 현재 흡연을 하고 있는 그룹에서는 1.75배(95% CI:1.55-1.82)로 증가하였다. 성별, 연령, 교육수준과 당뇨병 유무를 보정하고도 치주질환의 유병율에 대한 위험도는 전혀 피우지 않는 그룹보다 과거 흡연한 그룹에서 1.28배 (95% CI:1.08-1.53), 현재 흡연하는 그룹에서는 1.82배(95% CI:1.54-2.16)로 높았다. 이에 흡연과 치주질환이 연관성이 있는 것으로 나타나 적극적인 홍보를 통한 환자 스스로의 확고한 인식확립과 더불어 치과위생사는 진료실 내 체계적인 금연교육지도를 함으로써 치주 건강향상에 주력할 필요가 있다고 사료된다.

• 한국산학기술학회논문지
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• 제19권3호
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• pp.186-197
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• 2018

본 연구의 목적은 지역사회에 거주하는 한국 노인을 대상으로 한 신체활동 프로그램이 수면에 미치는 효과를 체계적이고 종합적으로 검증하기 위해 메타분석하는 것이다. 자료수집을 위해 PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) 가이드라인에 따라 2016년 11월 20일까지 출판된 연구물을 체계적으로 수집하고 각 기준에 따라 선별한 결과 총 7편이 메타분석 대상 논문으로 선정되었다. 자료 분석은 Comprehensive Meta-Analysis 3.0 프로그램을 이용하였으며, Q 검정을 통하여 연구들 사이의 동질성 여부를 검정한 후 개별 연구의 효과크기를 병합한 평균 효과크기를 산출하였다. 연구결과, 노인을 대상으로 한 신체활동 프로그램인, 힐링요가, 에어로빅댄스, 아쿠아로빅스, 한국무용, 베하스 운동, 운동프로그램, 타이치 운동이 수면에 미치는 총 효과는 Hedges' g=0.577(95% Confidence Interval (CI):0.337~0.817)로 유의한 효과크기를 보였다. 신체활동 프로그램 중 베하스 운동프로그램은 Hedges' g=0.758(95% CI:0.248~1.267)로 노인의 수면에 가장 큰 효과크기를 보였으며, 타이치 운동프로그램이 Hedges' g=0.697(95% CI:0.071~1.324), 운동프로그램은 Hedges' g=0.650(95% CI:0.141~1.159)의 순으로 효과크기를 보였다. 그러므로 지역사회 거주 노인의 수면의 질 향상을 위한 간호학적 중재를 적용함에 있어, 노인의 수면에 긍정적인 효과를 미치는 베하스 운동과 타이치 운동을 프로그램화 하여 적용하는 것이 도움이 될 것이다. 또한 노인의 수면에 유의한 효과를 미치지 않는 것으로 파악된 중재프로그램의 내용 및 특성, 문제점 등을 분석하여, 향후 노인을 대상으로 한 중재 개발 시 고려할 필요가 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7789-7794
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• 2015

Background: This study aimed to evaluate the impact of a community-based health education and communication programme on reducing liver fluke infections caused by the consumption of uncooked fish among people in a high-risk area of Thailand. Materials and Methods: The study was quasi-experimental in nature, with three-stages. Stage 1 involved a situational and capacity analysis of designated communities in Khon Kaen province. This was followed by the development of a model for community-based health education and communication to prevent liver fluke infections among high-risk people, and, lastly, implementation and evaluation of the model were performed. Data were collected using both qualitative and quantitative methods. In total, 390 people were surveyed, and quasi-experimental and comparison groups, each with 90 people, were assessed between May 2011 and April 2012. Analysis was using statistical OR, 95 % CI, the Willcoxon matched pairs signed ranks test, the chi-square test, and the Mann-Whitney U test. Results: The findings showed that most respondents had a high level of knowledge and understanding of liver fluke disease (89.5%, 95% CI:86.0-92.4), and positive attitudes toward the prevention of the disease (94.4%, 95% CI:91.6-96.4). However, with regard to changes in consumption of uncooked fish, most respondents were still in the pre-contemplation phase (55.1%, 95% CI:50.0-60.1), followed by the contemplation phase, 22.6%. Furthermore, four factors were found to be associated with the consumption of uncooked fish - the consumption of alcohol (OR 4.16, 95% CI:1.79-9.65), gender (OR 3.17, 95% CI:1.53-6.54), smoking (OR 3.03, 95% CI:1.31-7.05), and age 40 years and above (OR 2.68, 95% CI:1.02-7.05). After nine months of the health education and communication programme using local media based on local wisdom, culture and persons, the results showed that, compared to the control group, members of the experimental group had a higher level of knowledge, a better attitude and lower levels of ill-advised consumption behaviour. Also, it was found that consumption of uncooked fish, by an assessment of the level of stage of change, was reduced. (p-value 0.002). Conclusions: The health education and communication programme developed as part of the study was effective in changing the consumption of uncooked fish. Therefore, this approach should be promoted in other high-risk areas in Thailand in the future.

• 한국콘텐츠학회논문지
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• 제21권2호
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• pp.215-226
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• 2021

본 연구의 목적은 다회차 음주에 따른 장소별 음주량과 알코올의존을 분석하는 것이다. 국제 알코올 통제 연구의 일환으로 2012년에 수집된 단면 데이터를 사용하였으며, 만19-64세 음주자 1,789명 중 855명을 대상으로 하였다. 다회차 음주자 비율은 남성(χ²=37.607, p<.001), 학생(χ²=52.466, p<.001), 미혼자(χ²=34.205, p<.001), 흡연경험이 있거나 스트레스가 있는 군(χ²=40,09, p<.001, χ²=21.66, p<.001)에서 유의적으로 높았다. 특히, 미혼자, 흡연자, 스트레스군의 알코올 섭취량이 기혼자, 비흡연자, 비스트레스군보다 유의적으로 더 높았다. 다회차에 걸쳐 알코올 섭취량이 가장 높은 장소는 주류 판매 업종인 술집으로 나타났다(F=67.8g, p<0.001). 음주자의 음주차수가 증가할수록 총 알코올 섭취량이 증가하였으며(F=209.993, p<0.001) 알코올의존도 검사인 RAPS4와 DSM-IV에서 양성 반응을 나타낸 음주자의 수(%)가 각각(F=129.836, p<0.001; F=94.669, p<0.001) 증가하였다. 음주자 중 알코올의존 교차비는 남성이 여성보다 2.3(95% CI: 1.745-3.057)배, 무직자는 직장인보다 3차에서 3.2(95% CI: 1.053-9.838)배, 흡연자는 비흡연자보다 3차에서 3.9(95% CI: 1.230-12.292)배, 그리고 스트레스군도 비스트레스군보다 2.1(95% CI: 1.561-2.768)배 높았다. 결론적으로 음주차수가 증가할수록 흡연여부나 스트레스와의 관련성과 알코올 의존도가 높아져 알코올에 더 취약할 수 있음을 시사한다.

• Korean Journal of Radiology
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• 제20권8호
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• pp.1300-1310
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• 2019

Objective: To measure the diagnostic accuracy of percutaneous transthoracic needle lung biopsies (PTNBs) on the basis of the intention-to-diagnose principle and identify risk factors for diagnostic failure of PTNBs in a multi-institutional setting. Materials and Methods: A total of 9384 initial PTNBs performed in 9239 patients (mean patient age, 65 years [range, 20-99 years]) from January 2010 to December 2014 were included. The accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of PTNBs for diagnosis of malignancy were measured. The proportion of diagnostic failures was measured, and their risk factors were identified. Results: The overall accuracy, sensitivity, specificity, PPV, and NPV were 91.1% (95% confidence interval [CI], 90.6-91.7%), 92.5% (95% CI, 91.9-93.1%), 86.5% (95% CI, 85.0-87.9%), 99.2% (95% CI, 99.0-99.4%), and 84.3% (95% CI, 82.7-85.8%), respectively. The proportion of diagnostic failures was 8.9% (831 of 9384; 95% CI, 8.3-9.4%). The independent risk factors for diagnostic failures were lesions ≤ 1 cm in size (adjusted odds ratio [AOR], 1.86; 95% CI, 1.23-2.81), lesion size 1.1-2 cm (1.75; 1.45-2.11), subsolid lesions (1.81; 1.32-2.49), use of fine needle aspiration only (2.43; 1.80-3.28), final diagnosis of benign lesions (2.18; 1.84-2.58), and final diagnosis of lymphomas (10.66; 6.21-18.30). Use of cone-beam CT (AOR, 0.31; 95% CI, 0.13-0.75) and conventional CT-guidance (0.55; 0.32-0.94) reduced diagnostic failures. Conclusion: The accuracy of PTNB for diagnosis of malignancy was fairly high in our large-scale multi-institutional cohort. The identified risk factors for diagnostic failure may help reduce diagnostic failure and interpret the biopsy results.

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.903-907
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• 2015

Background: Among human epidermal growth factor receptor 2 (HER2)-positive breast cancer, more than half are also hormone receptor (HR)-positive. Although HR is a predictive factor for the efficacy of hormone therapy, there are still some uncertainties in regard to the effects on patients with HR-positive and HER2-positive metastatic breast cancers due to the potential resistance to hormone therapy caused by co-expression of HR and HER2. There are no clinical trials directly comparing the efficacy of hormonal therapy with chemotherapy. Materials and Methods: To examine the real-world effect of hormone therapy on patients with HR-positive and HER2-positive metastatic breast cancers, a cross-sectional study of a representative sample of the Chinese population was conducted. The study included 113 patients who received first-line and second-line palliative treatment between 2005 and 2010 in the Cancer Institute and Hospital, Chinese Academy of Medical Science. The effect of hormone therapy on overall survival (OS) was studied. Results: The patients who received hormone therapy (n=51) had better overall survival in contrast to those who received chemotherapy with anti-HER2 therapy (n=62) in first- or second-line treatment. The difference was of borderline statistical significance (51.8m vs 31.9m, p=0.065). In addition, the effect of hormone therapy did not differ significantly with other prognostic factors, including age (${\leq}50$ years or >50 years), disease free survival (${\geq}2$ years or < 2 years) and site of metastasis (visceral or bone/soft tissue). On multivariate analysis, administration of hormone therapy was associated with a trend toward a favorable prognosis (p=0.148, HR=0.693, 95%CI 0.422-1.139). Age more than 50 years was the sole independent harmful prognostic factor (p<0.001, HR=2.797, 95%CI 1.676-4.668). Conclusions: Our data suggest that hormonel therapy may improve outcomes of the patients with ER-positive and HER2-positive metastatic breast cancer.

• 대한의생명과학회지
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• 제16권4호
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• pp.323-330
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• 2010

Although copper and zinc are essential metals for human health, excessive level of these metals is toxic. Besides, aluminum is known to induce various adverse health effects including neurological disorders. Therefore, monitoring the human body burden of these metals is important in preventing adverse health effects. In this study, we assessed the exposure to copper, zinc, and aluminum among an adult population residing in Daegu and Kyungbuk areas. Based on data from 171 participants, we found that the geometric mean copper, zinc, and aluminum concentrations in hair were $15.1\;{\mu}g/g$ [95% confidence interval (CI): 13.1~17.5], 76.9 (95% CI: 70.4~84.1), and $1.11\;{\mu}g/g$ (95% CI: 0.81~1.51), respectively. The copper concentrations in hair were significantly related to age, education, and residence area. In addition, zinc concentrations in hair were significantly related to age, whereas higher hair aluminum concentrations were related to alcohol drinking. Correlations between copper and zinc in hair had a significant positive correlation. Our findings suggest that the body burden of copper, zinc, and aluminum varies according to demographic factors, and hair could be used as a valuable biological medium for metal exposure.

• Child Health Nursing Research
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• 제9권4호
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• pp.368-375
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• 2003

Purpose: The purpose of this study was to determine rate of breastfeeding practice at 3 months and to examine predictors for breastfeeding practice. Method: Study subjects were 114 mothers who gave birth at one hospital in Busan area. Data regarding breastfeeding practice and potentially related factors to breastfeeding were collected through a self-administered questionaire at 1 weeks and a telephone survey at 3 months. Logistic regression was used to identifiy significant the predictors on breastfeeding practice. Result: Rate of breastfeeding practice was 46.5% at three months of postpartum. The significant predictors for performing breastfeeding were lower the experience of breastfeeding trouble problem(OR=.88 compared with breastfeeding women, 95% CI; 78-.99), higher first breastfeeding satisfaction (OR=1.81 compared with non-breastfeeding women, 95% CI; 1.08-3.32), higher breastfeeding confidence(OR=1.84 compared with non-breastfeeding women, 95% CI; 1.08-3.32). Conclusion: The findings suggest the necessity of support program for mothers during the positive postpartum period to provide correct information about breastfeeding knowledge and attitude and to teach problem-solving skills for any breastfeeding problems for highere rate of breastfeeding practice

• Environmental Analysis Health and Toxicology
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• 제13권3_4호
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• pp.63-70
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• 1998

In order to elucidate the prevalence of anti-HEV, anti-HCV and HBsAg in ALT (Alanine Aminotransferase)-elevated patient group and healthy person control group, we examined anti-HEV, anti-HCV and HBsAg in 92 persons, respectively. The prevalence of anti-HEV in ALT-elevated patient group (4.3%) was not significantly higher than that (2.2%) of healthy person control group(P>0.05). While in healthy person control group the prevalence of anti-HEV in female (2.4%) was higher than that (2.0%) in male, and in ALT-elevated group male (4.8%) was higher than female (3.3%), there were no significances. The positive rate of anti-HEV was not significantly increased with age between healthy person control and ALT-elevated patient group. The odds ratio's of HEV, HCV and HBV with ALT-elevated patient group were 2.05 (95% CI: 0.31-16.54), 8.67 (95% CI: 1.06-188.63) and 7.23 (95% CI: 2.47-22.71), respectively, but had no significance. It was turned out that HCV and HBV were significantly correlated with ALT-elevated patient group, but HEV had no significance with it in this paper.

• PNF and Movement
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• 제17권2호
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• pp.253-261
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• 2019

Purpose: The purpose of this study was to identify the causal relationship between workplace stress and working posture and the development of work-related neck pain in office workers. Methods: The study participants included 62 office workers who had not experienced neck pain in the previous 12 months. A battery of measures to evaluate potential workplace risk factors in an office setting were conducted at baseline, and the 12-month incidence of work-related neck pain was reported via monthly questionnaires. Survival analysis was used to evaluate the longitudinal relationship between the workplace risk factors and the development of work-related neck pain. Results: The incidence of work-related neck pain was 1.91 (95% CI: 1.06-3.45) per 100 person months. The incidence of neck pain was predicted to be less likely to happen when workers had a more upright thorax posture during computer work (hazard ratio, 0.94; 95% CI: 0.89-0.99). However, stress may deteriorate the preventative effects of other risk factors on neck pain and showed a positive relationship with episodes of neck pain (hazard ratio, 1.37; 95% CI: 1.03-1.84). Conclusion: Understanding the psychophysiological effects of neck pain may explain the development of neck pain in office workers. Our interest in prevention plans and treatments should therefore involve a multifactorial pathology of neck pain in the workplace.