• 제목/요약/키워드: population-based study

검색결과 4,271건 처리시간 0.033초

Characterization analysis of Rongchang pig population based on the Zhongxin-1 Porcine Breeding Array PLUS

  • Dong Leng;Liangpeng Ge;Jing Sun
    • Animal Bioscience
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    • 제36권10호
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    • pp.1508-1516
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    • 2023
  • Objective: To carry out a comprehensive production planning of the existing Rongchang pig population from both environmental and genetic aspects, and to establish a closed population with stable genetic diversity and strict pathogen control, it is necessary to fully understand the genetic background of the population. Methods: We genotyped 54 specific pathogen free (SPF) Rongchang pigs using the Zhongxin-1 Porcine Breeding Array PLUS, calculated their genetic diversity parameters and constructed their families. In addition, we also counted the runs of homozygosity (ROH) of each individual and calculated the value of inbreeding coefficient based on ROH for each individual. Results: Firstly, the results of genetic diversity analysis showed that the effective population size (Ne) of this population was 3.2, proportion of polymorphic markers (PN) was 0.515, desired heterozygosity (He) and observed heterozygosity (Ho) were 0.315 and 0.335. Ho was higher than He, indicating that the heterozygosity of all the selected loci was high. Secondly, combining the results of genomic relatedness analysis and cluster analysis, it was found that the existing Rongchang pig population could be divided into four families. Finally, we also counted the ROH of each individual and calculated the inbreeding coefficient value accordingly, whose mean value was 0.09. Conclusion: Due to the limitation of population size and other factors, the genetic diversity of this Rongchang pig population is low. The results of this study can provide basic data to support the development of Rongchang pig breeding program, the establishment of SPF Rongchang pig closed herd and its experimental utilization.

경기 남서부지역의 인구특성 연구 (A Study on the Characteristics of Population Movement in South West Area of Kyonggi-do)

  • 최식인
    • 농촌지도와개발
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    • 제11권1호
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    • pp.83-93
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    • 2004
  • This paper investigated the characteristics of population structure and the determinants of population movement in the south west area of Kyonggi-do by grouping 9 cities in 3 categories and using Panel data of $1995{\sim}2001$. The major findings of this paper were identified as follows : 1) The population structure of regions was different to the stages of urbanization. The ratio of child and elder dependency was high in the rural regions and low in the urbanized regions. It was due to the movement of economically active population of $20{\sim}40$ aged groups, from rural regions to urban regions. This means that more productive segments of the rural population leave the country to the city. In addition. The ratio of male to female was higher in $20{\sim}40$ aged groups for rural regions. This suggested that young females moved from rural regions to urban regions more than young males in the process of industrialization. 2) Based in pooling regression, income was the most significant determinant that could explain the inter-regional and intra-regional movement of population for south west area studied, The next one was educational opportunity variable. The coefficients of income and education were 0.5, 0,7 for intra-regional migration and 0.01, 0.02 for interregional migration indicating that Todaro's hypothesis could be tested well rather than Tiebout' model for this area.

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도시 거리의 주간활동인구 측정과 해석: 서울시 유동인구 조사 사례 (How to Measure Daytime Population in Urban Streets?: Case of Seoul Pedestrian Flow Survey)

  • 변미리;서우석
    • 한국조사연구학회지:조사연구
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    • 제12권2호
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    • pp.27-50
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    • 2011
  • 도시의 행정수요 측정과 도시경제 운영을 위해 주간활동인구를 파악해야 할 필요성이 증가하였다. 상주인구를 보완하는 개념으로서 센서스의 통근 통학 자료에 근거를 둔 주간인구가 활용되고 있으나 서비스 경제가 압도적인 서울과 같은 대도시의 주간활동인구 파악에는 한계가 있다. 본 연구에서는 도시의 주간활동인구를 파악하기 위한 개념으로서 유동인구를 제시하고 서울시 유동인구 조사의 방법을 소개하였으며 주요 분석결과를 제시하였다. 유동인구 조사자료의 분석 결과 센서스 기반 주간인구에서는 파악할 수 없었던 시간대별, 공간대별 도시 주간활동인구의 분포를 밝힐 수 있었다. 끝으로 유동인구 조사자료를 통해 파악한 주간인구와 센서스 기반 주간인구를 자치구 수준에서 비교함으로써 유동인구 조사 자료의 주요 특성들을 밝혔다.

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유전자 알고리듬을 이용한 동역학적 구조물의 최적설계 (Optimal Design of Dynamic System Using a Genetic Algorithm(GA))

  • 황상문;성활경
    • 한국정밀공학회지
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    • 제16권1호통권94호
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    • pp.116-124
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    • 1999
  • In most conventional design optimization of dynamic system, design sensitivities are utilized. However, design sensitivities based optimization method has numbers of drawback. First, computing design sensitivities for dynamic system is mathematically difficult, and almost impossible for many complex problems as well. Second, local optimum is obtained. On the other hand, Genetic Algorithm is the search technique based on the performance of system, not on the design sensitivities. It is the search algorithm based on the mechanics of natural selection and natural genetics. GA search, differing from conventional search techniques, starts with an initial set of random solutions called a population. Each individual in the population is called a chromosome, representing a solution to the problem at hand. The chromosomes evolve through successive iterations, called generations. As the generation is repeated, the fitness values of chromosomes were maximized, and design parameters converge to the optimal. In this study, Genetic Algorithm is applied to the actual dynamic optimization problems, to determine the optimal design parameters of the dynamic system.

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다목적 함수 최적화를 위한 게임 모델에 기반한 공진화 알고리즘에서의 해집단의 다양성에 관한 연구 (Study on Diversity of Population in Game model based Co-evolutionary Algorithm for Multiobjective optimization)

  • 이희재;심귀보
    • 한국지능시스템학회논문지
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    • 제17권7호
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    • pp.869-874
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    • 2007
  • 다목적 함수의 최적화 문제(Multiobjective optimization problems)의 경우에는 하나의 최적해가 존재하는 것이 아니라 '파레토 최적해 집합(Pareto optimal set)'이라고 알려진 해들의 집합이 존재한다. 이러한 이상적 파레토 최적해 집합과 가까운 최적해를 찾기 위한 다양한 해탐색 능력은 진화 알고리즘의 성능을 결정한다. 본 논문에서는 게임 모델에 기반한 공진화 알고리즘(GCEA: Game model based Co-Evolutionary Algorithm)에서 해집단의 다양성을 유지하여, 다양한 비지배적 파레토 대안해(non-dominated alternatives)들을 찾기 위한 방법을 제안한다.

Performance of Spiked Population Models for Spectrum Sensing

  • Le, Tan-Thanh;Kong, Hyung-Yun
    • Journal of electromagnetic engineering and science
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    • 제12권3호
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    • pp.203-209
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    • 2012
  • In order to improve sensing performance when the noise variance is not known, this paper considers a so-called blind spectrum sensing technique that is based on eigenvalue models. In this paper, we employed the spiked population models in order to identify the miss detection probability. At first, we try to estimate the unknown noise variance based on the blind measurements at a secondary location. We then investigate the performance of detection, in terms of both theoretical and empirical aspects, after applying this estimated noise variance result. In addition, we study the effects of the number of SUs and the number of samples on the spectrum sensing performance.

Bayesian estimation for finite population proportion under selection bias via surrogate samples

  • Choi, Seong Mi;Kim, Dal Ho
    • Journal of the Korean Data and Information Science Society
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    • 제24권6호
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    • pp.1543-1550
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    • 2013
  • In this paper, we study Bayesian estimation for the finite population proportion in binary data under selection bias. We use a Bayesian nonignorable selection model to accommodate the selection mechanism. We compare four possible estimators of the finite population proportions based on data analysis as well as Monte Carlo simulation. It turns out that nonignorable selection model might be useful for weekly biased samples.

A Study on Estimating Population Mean by Use of Interpolation and Extrapolation with Balanced Systematic Sampling

  • Kim, Hyuk-Joo
    • Journal of the Korean Data and Information Science Society
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    • 제10권1호
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    • pp.91-102
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    • 1999
  • A new method is developed for estimating the mean of a population which has a linear trend. The suggested estimator is based on the balanced systematic sampling method and the concept of interpolation and extrapolation. The efficiency of the proposed method is compared with that of conventional methods.

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Chronic Pain and Its Determinants: A Population-based Study in Southern Iran

  • Zarei, Safar;Bigizadeh, Shiva;Pourahmadi, Mohammad;Ghobadifar, Mohamed Amin
    • The Korean Journal of Pain
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    • 제25권4호
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    • pp.245-253
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    • 2012
  • Background: Prevalence of chronic pain and its association with demographic characteristics have been reported by different studies from different geographical regions in the world. However, data from many Middle East countries including Iran (especially southern Iran) are scare. The aim of the present study was to demonstrate the prevalence of chronic pain and its association with demographic, psychological and socioeconomic factors in an Iranian population. Methods: In this population-based survey, the target population was comprised of subjects aged 20 to 85 years residing in Jahrom, southern Iran during 2009-2011. All eligible subjects were invited to participate in the study. Before a detailed questionnaire was given; face to face interviews were done for each individual. Results: There were 719 men and 874 women with an average age of 40.5 years at the onset of the study. Among the study population, 38.9% (620/1,593) complained of chronic pain, of whom 40.8% (253/620) were men and 59.2% (367/620) were women. Foot and joint pain were observed in 31.9%. Hip and spine pain, migraine and tension headaches, heart pain, and abdomen pain were observed in 21.5%, 15.5%, 9.5%, and 8.0% of chronic pain cases, respectively. There was a significant association among the covariables age, sex, overweight, educational level, income, and type of employment with chronic pain as the dependent variable (P < 0.0001). Conclusions: Our findings show the prevalence of chronic pain and its association with demographic, psychological and socioeconomic factors. Individuals with low incomes and less education became accustomed to pain due to a lack of knowledge.

Epidemiology and Outcomes of Traumatic Brain Injury in Elderly Population : A Multicenter Analysis Using Korean Neuro-Trauma Data Bank System 2010-2014

  • Eom, Ki Seong
    • Journal of Korean Neurosurgical Society
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    • 제62권2호
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    • pp.243-255
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    • 2019
  • Objective : Although traumatic brain injury (TBI) occurs in people of all age groups, the elderly population is at a particular risk. The proportion of elderly population in the society is markedly increasing and Korea is one of the most rapidly aging societies. Here, we analyzed the data from 904 patients older over 65 years who were registered in the Korean Neuro-Trauma Data Bank System (KNTDBS). Methods : The Korean Society of Neurotraumatology recorded data from 20 institutions between September 2010 and March 2014. This retrospective study examined the clinical epidemiology, sex difference, outcome epidemiology, sociodemographic variables, and outcomes in the geriatric population related to TBI based on data from the KNTDBS. Results : The study included 540 men and 364 women. The age distributions in the male and female groups were statistically significantly different. The most common cause of trauma was a fall and diagnosis was acute subdural hematoma. The incidence was the highest in men aged 80-84 years and in women aged 75-79 years. The most common time of arrival to hospital after TBI was within 1 hour and 119 rescue team provided first aid earliest to patients with TBI. The mortality rate stratified according to the cause of trauma was significantly different, with mortality rates of 3.77% in fall and 11.65% in traffic accident. The mortality rates according the severity of brain injury, Glasgow Coma Scale score, and treatment were statistically significant. Conclusion : To our knowledge, this study is the first to focus on elderly patients with TBI in Korea and particularly investigate mortality and characteristics related to TBI-related death based on data from the KNTDBS. Although the study has some limitations, our results may be used to obtain useful information to study targeted prevention and more effective treatment options for older TBI patients and establish novel treatment guidelines and health polish for the geriatric population.