• Title/Summary/Keyword: population phenomena

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Association of KIR (Killer Cell Immunoglobulin-like Receptor) Genotype with Psoriasis in Korean Population (한국인에서 건선과 KIR (Killer Cell Immunoglobulin-like Receptor) 유전자형 사이의 연관성)

  • Choi, Eun-Jung;Choi, Hee-Baeg;Kim, Su-Yeon;Yoon, Ho-Yeul;Park, Min-Ji;Kim, Tae-Yoon;Kim, Tai-Gyu
    • IMMUNE NETWORK
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    • v.5 no.3
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    • pp.179-185
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    • 2005
  • Background: Psoriasis is a multifactorial autoimmune skin disease with a pathogenesis that has remained obscure. Recently, T cells bearing natural killer receptors (NKRs) were precisely and strongly targeted as new putative pathogenic immunocytes in psoriasis. Among NKRs, killer cell immunoglobulin-like receptor (KIR) is the major molecule recognizing HLA class I allotypes and might be closely related to psoriasis. Methods: To investigate the association of KIR genotype and patients with psoriasis in Korean, we defined the 14 KIR genotypes in 96 patients with psoriasis and 86 healthy controls using PCR-SSP methods. Results: The frequencies of KIR2DS4 and KIR3DL1 were significantly decreased in psoriasis compared with controls (RR=0.21, p<0.02). When patients were divided into two subgroups at the age of onset, type I (<30 years) and type II ($({\geq}30$ years) respectively, these phenomena were similarly observed independent of groups divided (type I: RR=0.26, p<0.005; type II: RR=0.14, p<0.0006). When the patients were divided into subgroups according to the age of onset and family history, the frequencies of KIR2DS4, KIR3DL1, and KIR2DS3 were significantly decreased in type I compared with type II psoriasis (3DL1, 2DS4: p<0.004; 2DS3: p<0.04) and were significantly decreased in psoriasis without family history compared to with family history (3DL1, 2DS4: p<0.007; 2DS3: p<0.05). The frequency of haplotype combination BB was significantly increased in psoriasis compared with controls (RR=2.74, p<0.009). Conclusion: These results suggest that KIR genotype is a factor for the occurrence and development of psoriasis and in future how combinations of HLA and KIR genes influence psoriasis needs to be defined.

A Study on the Estiblishment of Space Planning on Myeon Center according to Regional Characteristics (지역특성에 따른 면소재지 공간계획수립에 관한 연구)

  • Yoon, Junsang;Kim, Sungrok
    • Journal of Agricultural Extension & Community Development
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    • v.20 no.2
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    • pp.407-429
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    • 2013
  • Although rural areas account for more than 80% of the total land area of South Korea, most of them are deteriorated and living environment is inconvenient. In addition, the migration of young generation to urban areas and ageing have reduced the population and caused not only cavitation phenomena of villages but also stagnant communities. As for one of the rural areas, the seat of Myeon Office located in Oesan-myeon, Buyeo-gun, Chungcheongnam-do, this study presented not a plan only for strengthening hub functions but the methodology of the complex development plan in consideration of the regional characteristics in the comprehensive improvement project in seat of Myeon Office. From the perspective of enhancing the function of the seat of Myeon Office, it is inevitable to establish plans based on hardware. However, empowerment of the residents in the targeted areas also works as an important factor. In other words, each project promoted by the plan will be mainly operated by the local residents. Therefore, it is necessary to establish a management system of this. The success or failure of the established plan is based on the accurate survey of the issues of the targeted areas and demand, and this depends on participation and positive response of the residents of the targeted areas. That is, the method as a 'local community network' is required in order to increase the effect of resident participation in the planning area.

The Phenomenoloical Study on the Stress of Family Caregivers with Demented Elderly (치매노인 부양가족의 스트레스에 관한 현상학적 연구)

  • Lee, Young-man;Shin, Dong-yeol
    • Industry Promotion Research
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    • v.5 no.2
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    • pp.41-50
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    • 2020
  • WIn Korea, the rapid rise of elderly population and dementia prevalence resulting from the unprecedently rapid aging in the world is being emerged as a serious social issue. Caring the elderly with dementia is a different way from a general life and is a world which new cultural existential relationships are interlaced from the relationship viewpoint. From this aspect, the psychological matter of family caring a demented elderly needs to be studied for existential understanding in depth and fundamentally. This study focused on in-depth understanding and description of the stress phenomena experienced by family caregivers with a demented elderly based on Giorgi's method among phenomenological research methods and using existential group counseling techniques. Total 8 sessions of existential group counseling were conducted. This study drew out the outcomes(emotional stress, psychosocial stress, time-dependent stress) of participants' self-awareness experiences by applying 4 steps of Giorgi's phenomenological research methodology based on the Existential Philosophy to participant's intensive statements about stress of family caring a demented elderly drawn out of the existential group counselling sessions. It is hoped that understanding the pain of the supporters who cannot express their own pains through the research results and their self-help group counseling activities will become active, contributing to the health of our society which is about to enter post-aged society.

A Study on Stochastic Estimation of Monthly Runoff by Multiple Regression Analysis (다중회귀분석에 의한 하천 월 유출량의 추계학적 추정에 관한 연구)

  • 김태철;정하우
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.22 no.3
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    • pp.75-87
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    • 1980
  • Most hydro]ogic phenomena are the complex and organic products of multiple causations like climatic and hydro-geological factors. A certain significant correlation on the run-off in river basin would be expected and foreseen in advance, and the effect of each these causual and associated factors (independant variables; present-month rainfall, previous-month run-off, evapotranspiration and relative humidity etc.) upon present-month run-off(dependent variable) may be determined by multiple regression analysis. Functions between independant and dependant variables should be treated repeatedly until satisfactory and optimal combination of independant variables can be obtained. Reliability of the estimated function should be tested according to the result of statistical criterion such as analysis of variance, coefficient of determination and significance-test of regression coefficients before first estimated multiple regression model in historical sequence is determined. But some error between observed and estimated run-off is still there. The error arises because the model used is an inadequate description of the system and because the data constituting the record represent only a sample from a population of monthly discharge observation, so that estimates of model parameter will be subject to sampling errors. Since this error which is a deviation from multiple regression plane cannot be explained by first estimated multiple regression equation, it can be considered as a random error governed by law of chance in nature. This unexplained variance by multiple regression equation can be solved by stochastic approach, that is, random error can be stochastically simulated by multiplying random normal variate to standard error of estimate. Finally hybrid model on estimation of monthly run-off in nonhistorical sequence can be determined by combining the determistic component of multiple regression equation and the stochastic component of random errors. Monthly run-off in Naju station in Yong-San river basin is estimated by multiple regression model and hybrid model. And some comparisons between observed and estimated run-off and between multiple regression model and already-existing estimation methods such as Gajiyama formula, tank model and Thomas-Fiering model are done. The results are as follows. (1) The optimal function to estimate monthly run-off in historical sequence is multiple linear regression equation in overall-month unit, that is; Qn=0.788Pn+0.130Qn-1-0.273En-0.1 About 85% of total variance of monthly runoff can be explained by multiple linear regression equation and its coefficient of determination (R2) is 0.843. This means we can estimate monthly runoff in historical sequence highly significantly with short data of observation by above mentioned equation. (2) The optimal function to estimate monthly runoff in nonhistorical sequence is hybrid model combined with multiple linear regression equation in overall-month unit and stochastic component, that is; Qn=0. 788Pn+0. l30Qn-1-0. 273En-0. 10+Sy.t The rest 15% of unexplained variance of monthly runoff can be explained by addition of stochastic process and a bit more reliable results of statistical characteristics of monthly runoff in non-historical sequence are derived. This estimated monthly runoff in non-historical sequence shows up the extraordinary value (maximum, minimum value) which is not appeared in the observed runoff as a random component. (3) "Frequency best fit coefficient" (R2f) of multiple linear regression equation is 0.847 which is the same value as Gaijyama's one. This implies that multiple linear regression equation and Gajiyama formula are theoretically rather reasonable functions.

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Prediction of Evacuation Time for Emergency Planning Zone of Uljin Nuclear Site (울진원전 방사선비상계획구역에 대한 소개시간 예측)

  • Jeon, In-Young;Lee, Jai-Ki
    • Journal of Radiation Protection and Research
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    • v.27 no.3
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    • pp.189-198
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    • 2002
  • The time for evacuation of residents in emergency planning zone(EPZ) of Uljin nuclear site in case of a radiological emergency was estimated with traffic analysis. Evacuees were classified into 4 groups by considering population density, local jurisdictions, and whether they ate residents or transients. The survey to investigate the behavioral characteristics of the residents was made for 200 households and included a hypothetical scenario explaining the accident situation and questions such as dwelling place, time demand for evacuation preparation transportation means for evacuation, sheltering place, and evacuation direction. The microscopic traffic simulation model, CORSIM, was used to simulate the behavior of evacuating vehicles on networks. The results showed that the evacuation time required for total vehicles to move out from EPZ took longer in the daytime than at night in spite that the delay times at intersections were longer at night than in the daytime. This was analyzed due to the differences of the trip generation time distribution. To validate whether the CORSIM model fan appropriately simulate the congested traffic phenomena assumable in case of emergency, a benchmark study was conducted at an intersection without an actuated traffic signal near Uljin site during the traffic peak-time in the morning. This study indicated that the predicted output by the CORSIM model was in good agreement with the observed data. satisfying the purpose of this study.

The Myth of Youthism (청소년주의와 세대 신화)

  • Won, Yong-Jin;Lee, Dong-Yeon;Nho, Myung-Woo
    • Korean journal of communication and information
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    • v.36
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    • pp.324-347
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    • 2006
  • `Youthism` is pushing the youth research field into a trap of binarism fallacy. It tends to divide the whole population into the young and the old, and further gives an acceleration toward moving the division into the discursive realm of generation gap. The discursive transference is not taking place without any reasonable grounds. The series of discourse is based on two significant phenomena: changes in media background and longer schooling than ever before. Media environment overriding youth culture binds the young in a group and makes them enjoy homogeneous cultural genres. And schooling also seems to play an important role for the youth to have same cultural menus regardless of region, social strata, cultural background. But we need to recognize that after getting into the adulthood, they are not existing in the form of alliance. The youth are not in a homogeneous group. Neither are their culture. The youth are consisted of a variety of groups along such variables as gender, class of their parents. They tend to make distinction not only from the older generation but from the other peer groups. Unless avoiding the trap of youthism, we are blamed for closing eyes to the youth's desire to be distinctive among themselves. Youthism seems to be an active myth even in our academic society.

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Consideration of preservation methods for plant genetic resources in natural monument - Focusing on preparation for becoming effective of Nagoya Protocol - (천연기념물 식물유전자원의 보존방안 고찰 - 나고야의정서 발효 대비 중심으로 -)

  • Kim, Jung A;Kim, Hyo Jeong;Shin, Jin Ho;Kim, Dae Yeol;Jo, Woon Yeon
    • Korean Journal of Agricultural Science
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    • v.41 no.3
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    • pp.193-203
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    • 2014
  • Natural Monument is a designated cultural property as part of the country. According to Article 2 of the Cultural Properties Protection Act, a national, ethnic and global heritage artificially or naturally formed, with a great historical, artistic, scientific and landscape significance is defined as a cultural heritage. Animals, plants, topography, geology, minerals, caves, biological products and special natural phenomena, having a great of historic, scenic and scientific value, are defined as the monument. According to Article 3 of Cultural Properties Protection Act, the conservation, management and utilization of National Heritage should be kept intact in its original form. So, Natural monuments are managing as retained its original form under the Basic Principles of current law. The highest population of coniferous tree in natural monument plant is ginkgo tree including 22 objects, followed by pines, junipers that order. And in case of broadleaf tree, there are zelkova trees, retusa fringe trees, pagoda trees, cork oaks, silver magnolias and etc. There are many of reported efficacy in available natural monument plants. The efficacy of plant species on pharmaceutical like anti-cancer, anti-diabetic, anti-obesity, antioxidant activity, neuroprotective, improves cholesterol, anti-inflammatory, liver protection and anti-bacterial efficacy, on cosmetics and beauty like the inhibiting formation of skin wrinkles, whitening effect, variety of materials and the efficacy of the proposed utilization of its various papers and etc have been widely reported. Before the Nagoya Protocol enters into force, the future role of the National Research Institute for Cultural Properties Administration of Cultural Heritage should be obtain a legal right to manage the social, cultural and national natural monument with emotional value to the plant genetic resource as a natural monument efficient ways to study and preserve traditional knowledge biological resources by securing a claim to the sovereignty of the material will be ready.

Community Health Practitioner's Commitment into Community : on the Aspect of Primary Health Care (보건진료원의 지역사회 몰입과정)

  • Yun, Soon-Nyoung;Kim, Young-Im;Choi, Jeong-Myung
    • Research in Community and Public Health Nursing
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    • v.6 no.2
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    • pp.173-182
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    • 1995
  • Primary health care(PHC) has been established since A Health Law for rural residents has been legislated in 1980 following the WHO declaration, 'Health for All 2000'. in 1978. PHC services are presently assumed to be provided by 2038 Community Health Practitioners(CHP) to about 28% out of rural population in Korea. Most CHPs have confronted the adaptation process to the community being practiced although a CHP's role is to evoke community participation for the improvement of their health by themselves. So the purpose of this study is to describe and explain of the commitment of CHPs into the community. Data were collected by direct interview and tape-recording under subjects' permission till theoretical saturation were occured from 6 CHPs. The subjects were 41 years old and have served in the community for 9 years in average. Main questions and concepts were explored from data according to the procedure of the grounded theory methodology. The results are as follows. 1) The number of the main concepts were twenty four that identified Motive, Desire, Personal characteristics, Unfamiliarity, Denial, Feeling of isolation, Self-sacrifice, Kindness, Patience, Assimilation, Respect for the residents, Support by the family, Support by the residents, Achievement, Acceptance of realities, Use of resources, Inducement of cooperation from the residents, Changes of the difference from time orientation between CHP and residents, Attitude as a official, Technical support, Cost management, Satisfaction level, Acknowledgement by the residents and discrepancy. 2) The twenty four concepts were categorized to seven groups such as Motivation, Feeling of Heterogeneity, Self-discipline, Social support, Induced changes in the attitudes of residents, Familarity and Persistent discrepancy. 3) The categorized groups were analyzed on the base of the Causal Conditions, Central Phenomena, Contexts, Intervening Conditions, Action / Interaction Strategies, and Consequences. Central phenomenon in this study was identified to be the feeling of heterogeneity. Community health practitioners experienced unfamiliarity and denial from the community and felt themselves isolated in the first. In time, they won the trust of residents by their efforts including self-sacrifice, kindness, patience, and assimilation. Afterward, practitioners got self-confidence and familiarity with lesser feeling of heterogeneity. Nevertheless, practitioners could not commit themselves completely because of the persistent discrepancy between CHP and residents. 4) On the commitment process, the CHPs' feeling of heterogeneity were decresed and social support increesed and newly evolved induced change of residents through the continuous interaction between CHP and them The contribution of this study would be concluded as follows. 1) It is expected that effective strategies for more rapid committment into the community can be developed based on this study. 2) More easy committment would be possible for the newly appointed CHP through understanding of the committment process identified on this study.

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An Analysis of Master's and Doctoral Thesis in Nursing - Centered on a Nursing, an Education, and a Public Health Graduate College - (간호학 석.박사 학위논문의 분석)

  • Chon, S.J.;Hong, K.P.;Yang, W.Y.;Lee, J.J.;Lee, B.S.;Hur, H.K.;Kim, J.I.;Yim, J.Y.;In, J.Y.
    • The Korean Nurse
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    • v.33 no.2
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    • pp.45-58
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    • 1994
  • This study was conducted for the purpose of identifying the trends of nursing research and to suggest the direction of future research in the graduate levels of the study. The data was collected from 469 abstracts of master's and doctoral rapers from three graduate schools, one in Nursing, another in Education, and the other in Public Health Graduate College. The results of the study are as follows: The number of research was increased from 102 to 286 between the 1970 s and 1980's. The most frequently employed research design was descriptive studies in the master's level, but there was some balance between descriptive and experimental studies along with some qualitative approaches in the doctoral thesis. Patients were the most often studied sample group reaching 42% of the cases, though it Was noted that there was steady shift: toward the non-ratient population. With this shifting of the study sample, the places of the study also have showed some changes moving toward community. The most widely studied area was in clinical practice. Chronic illness, preventive, and health promoting areas of studies also increased in numbers. However, most of them were at the descriptive level of phenomena and only a few were concerned with cost/effective measures of nursing intervention. The number of variables studied repeatedly more than five times was 43. They were not only physical but also psychosocial aspects which imply the efforts to incorporate the whole person in nursing discipline. However, most researches with repeated studies showed little relation to previous studies, and thus little accumulation in knowledge. There was also little evidence of linkage to nursing theory in most studies of master's level. For the doctoral rapers, 17 out of 51 rapers showed specific theories related to the researches. Based on the above findings, the following suggestions were made. Various research design should be employed including case studies, historical studies, as well as qualitative approaches. There should be more effort to establish linkage between theory and research. The areas needing more attention are Korean Nursing History, Ethics in our Culture, Cost/Effective Measures of Nursing Intervention, Concept and Thory Development, and the Strategies for the Implication of the Research Results in clinical practice.

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Study on the Air Insulation Design Guideline for ±500 kV Double Bipole Transmission Line with Metallic Return Conductor (도체귀로형 ±500 kV Double Bipole 송전선로 공기절연에 관한 연구)

  • Shin, Kooyong;Kwon, Gumin;Song, Seongwhan;Woo, Jungwook
    • KEPCO Journal on Electric Power and Energy
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    • v.5 no.3
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    • pp.141-147
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    • 2019
  • Recently, the biggest issue in the electricity industry is the increase in renewable energy, and various technologies are being developed to ensure the capacity of the power system. In addition, super-grids linking power systems are being pushed to utilize eco-friendly energy between countries and regions worldwide. The HVDC transmission technology is required to link the power network between regions with different characteristics of the power system such as frequency and voltage. Until now, Korea has applied HVDC transmission technology that connects mainland and Jeju Island with submarine cables. But, the HVDC transmission technology is still developing for long-distance high-capacity power transmission from power parks on the east coast to load-tight areas near the metropolitan area. Considering the high population density and mountainous domestic environment, it is pushing for commercialization of the design technology of the ${\pm}500kV$ Double Bipole with metallic return wire transmission line to transmit large-scale power of 8 GW using minimal right of ways. In this paper, the insulation characteristics were studied for the design of double-bipole transmission tower with metallic return wire, which is the first time in the world. And the air insulation characteristics resistant to the various overvoltage phenomena occurring on transmission lines were verified through a full-scale impulse voltage test.