• KDI Journal of Economic Policy
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• v.41 no.1
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• pp.1-14
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• 2019

This paper studies whether export diversification mitigated the negative effect of the global financial crisis on exports using the Korean case. Specifically, we use annual data on the exports of 24 Korean manufacturing industries from 2000 to 2016 and examine whether the negative effect of the crisis on exports was less prevalent in industries that were more diversified in terms of country and product. We also examine whether export competitiveness, as measured by the revealed comparative advantage index by industry, had a mitigating effect on trade during the crisis. In order to study these issues, we use panel regression with a fixed-effect model for 24 Korean manufacturing industries. From our empirical analysis, we find that country diversification weakened the negative impact of the global financial crisis on Korea's exports, whereas neither product diversification nor export competitiveness did so.

• Journal of Digital Convergence
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• v.14 no.5
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• pp.21-37
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• 2016

The purpose of study was to examine the entrepreneurial supporting policy and the entrepreneurship which can affect the entrepreneurial intention, and to prove the moderating effect of the business failure burden and the self-efficacy on the relationship of the entrepreneurial supporting policy, entrepreneurship and the entrepreneurial intention through the empirical study in the fusion of industries. We used data from 321 survey participants by using structured questionnaires, excluding dishonest respondents, and statistical analysis was conducted using SPSS 18.0 statistic package. We used hierarchical regression technique to prove our hypothesis. The results showed that education and marketing support which are part of the entrepreneurial supporting policy in the fusion of industries will have positive influence on innovativeness, pro-activeness and risk acceptability which are part of entrepreneurship. It has been reported that only funding support has positive influence on entrepreneurship pro-activeness. The results also indicated that the entrepreneurial supporting policy will have positive influence on the entrepreneurial intention, but business failure burden and self-efficacy will have no moderating effect in the relation between the entrepreneurial supporting policy and the entrepreneurship. The theoretical and practical implications of the findings were discussed and the directions for future research were presented.

• Journal of Korean Neurosurgical Society
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• v.63 no.5
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• pp.566-578
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• 2020

Objective : Radiation is known to induce autophagy in malignant glioma cells whether it is cytocidal or cytoprotective. Dexamethasone is frequently used to reduce tumor-associated brain edema, especially during radiation therapy. The purpose of the study was to determine whether and how dexamethasone affects autophagy in irradiated malignant glioma cells and to identify possible intervening molecular pathways. Methods : We prepared p53 mutant U373 and LN229 glioma cell lines, which varied by phosphatase and tensin homolog (PTEN) mutational status and were used to make U373 stable transfected cells expressing GFP-LC3 protein. After performing cell survival assay after irradiation, the IC₅₀ radiation dose was determined. Dexamethasone dose (10 μM) was determined from the literature and added to the glioma cells 24 hours before the irradiation. The effect of adding dexamethasone was evaluated by cell survival assay or clonogenic assay and cell cycle analysis. Measurement of autophagy was visualized by western blot of LC3-I/LC3-II and quantified by the GFP-LC3 punctuated pattern under fluorescence microscopy and acridine orange staining for acidic vesicle organelles by flow cytometry. Results : Dexamethasone increased cell survival in both U373 and LN229 cells after irradiation. It interfered with autophagy after irradiation differently depending on the PTEN mutational status : the autophagy decreased in U373 (PTEN-mutated) cells but increased in LN229 (PTEN wild-type) cells. Inhibition of protein kinase B (AKT) phosphorylation after irradiation by LY294002 reversed the dexamethasone-induced decrease of autophagy and cell death in U373 cells but provoked no effect on both autophagy and cell survival in LN229 cells. After ATG5 knockdown, radiation-induced autophagy decreased and the effect of dexamethasone also diminished in both cell lines. The diminished autophagy resulted in a partial reversal of dexamethasone protection from cell death after irradiation in U373 cells; however, no significant change was observed in surviving fraction LN229 cells. Conclusion : Dexamethasone increased cell survival in p53 mutated malignant glioma cells and increased autophagy in PTEN-mutant malignant glioma cell but not in PTEN-wildtype cell. The difference of autophagy response could be mediated though the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin signaling pathway.

• 한국디지털정책학회:학술대회논문집
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• 2006.12a
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• pp.11-18
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• 2006

The purpose of this paper is to find an appropriate policy for local government innovation step by step. In order to accomplish this purpose, we considered the characteristics and situation of Gumi city. Specifically, we analyzed the win-win strategy of the department for the largest local administration innovation. Finally, we found that the chief executive's leadership and other strategies such as the adjustment of the innovation propulsion system are key factors. Also, Managing the resistance to change appeared during the process of local administrative innovation is important . The failure of the policy for local government innovation is caused by the failure to manage the resistance Thus for government innovation to succeed, correct informal ion provision, comprehensive participation of public officials and effect ive management of resistance is necessary.

• Journal of the Korean Operations Research and Management Science Society
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• v.24 no.3
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• pp.39-47
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• 1999

It has been concluded that the performance of class-based storage policy is better than the performance of random storage policy in the literature. However, the rack shortage problem assigned to the 1st class items makes the decision hard to apply the class-based storage policy in practice. In this paper, a new common zone concept is introduced between two classes to resolve the problem with class-based storage policy. The common zone is the area to accept items from both classes. An AS/RS model is developed for computer simulation study and the effect of common area sizes with various AS/RS operation conditions is analyzed.

• STI Policy Review
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• v.1 no.3
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• pp.53-68
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• 2010

This paper empirically evaluates the effects of regional and industrial R&D on the performances of individual firms in two separated stages: (1) the stage of technological outcome from R&D and (2) the stage of economic outcome from technological outcome. Technological spillovers are separated from negative congestion effects through the stage-specific estimation. The firm-level Korean Innovation Survey data merit in coping with the endogeneity problem inherent in the estimation of spillovers. The estimation results show that: (1) there exist significant R&D spillovers both in regional and industrial dimensions, (2) the hypothesized technological spillovers and economic congestion effects are both in effect, and (3) firms with smaller individual R&D investments show greater spillovers.

• Management Science and Financial Engineering
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• v.15 no.1
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• pp.33-49
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• 2009

We examine the effectiveness of the conventional (Q, r) model in managing production-inventory systems with finite capacity, stochastic demand, and stochastic order processing times. We show that, for systems with finite production capacity, order replenishment lead times are highly sensitive to loading and order quantity. Consequently, the choice of optimal order quantity and optimal reorder point can vary significantly from those obtained under the usual assumption of a load-independent lead time. More importantly, we show that for a given (Q, r) policy the conventional model can grossly under or over-estimate the actual cost of the policy. In cases where a setup time is associated with placing a production order, we show that the optimal (Q, r) policy derived from the conventional model can, in fact, be infeasible.

• Journal of Agricultural Extension & Community Development
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• v.11 no.2
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• pp.291-301
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• 2004

As Russian government signs the Kyoto Protocol on November 2004, it will go into effect on Feb. 16 2004. Under the Protocol, 38 industrialized countries are to reduce their combined emissions of six major greenhouse gases, including carbon dioxide and methane, to below 1990 levels during the 2008-2012 period. Korea ratified the Protocol in 2002 and is currently exempt from the reduction measures. It is expected, however, that Korea will be pressured to join the reduction scheme from 2013. Although the Kyoto Protocol is national-level agreement each country's urban governments are expected and have to play important role to make it successful one. It is more so for such mesa cities as Seoul which has experienced rapidly worsening environment recent years. Statistics shows that the annual average temperature in Seoul has increased by $1.5^{\circ}C$ for the last century, which is much higher than the national average. 'Heat Island' effect is not unusual any more in Seoul. This study reviews the key points of the Kyoto Protocol, urban warming phenomena in Seoul and its policy responses. In doing so, this study evaluates Tokyo case as a comparative one. It is found that Seoul needs to develop more concrete and feasible policy measures to get current efforts more effective.

• The Korean Journal of Health Service Management
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• v.9 no.4
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• pp.157-169
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• 2015

Objectives : The aim of this study was to investigate the effect of various Republic of Korea policies, including the medicine cost rationalization policy implemented By investigating the management strategy/performance changes of the industry caused by such policies. Methods : Pharmaceutical companies listed on the national stock exchange and the KOSDAQ were examined for 10 years from 2004 to 2013. Their financial statements were collected and market changes before and after drug price policy implementations were compared. Results : From the result of this research, among the medicine related policies, the drug price rationalization policy was found to have a significant effect on business management strategies in terms of safety, profitability and growth potential after its implementation. After the drug pricing transparency policy was implemented, management strategies were affected significantly in terms of safety and profitability. Conclusions : As a result, all of the medicine related policies were found to have regulatory effects. Based on these findings, implications, research limitations and future study plans are presented.

• Journal of National Security and Military Science
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• s.15
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• pp.117-151
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• 2018

The development of local defense parts has played a role a pure function such as maintenance of stable procurement source of military goods, provision of timely supply, establishment of self-defense base, creation of import substitution effect considering the whole life-cycle cost, reduction of foreign currency and protection of domestic defense industry. However, as the development success rate is deteriorating, it is time to analyze the related policies and improve the system. In order to improve the success rate of development of parts for the defense sector, it is necessary to unify the separated policies by the development-related departments and strengthen the policy support for the development companies to actively participate in the development. In addition, it is necessary to improve the paradigm for the selection of development items and change the authority of selecting development items and to delegate authority to create synergies. Parts localization development policy improvement is military support side it will contribute to strengthening defense power management by organically combining with technological development aspect and economical aspect. Development items will be linked to defense exports, which will have a remarkable effect on sales growth and job creation effects. The development of local defense parts is spreading.