• Natural Product Sciences
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• v.24 no.4
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• pp.259-265
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• 2018

The three flavone glycosides, 4'-O-methylisoscutellarein 7-O-(6'''-O-acetyl)-${\beta}$-D-allopyranosyl(1${\rightarrow}$2)-${\beta}$-D-glucopyranoside (1), isoscutellarein 7-O-(6'''-O-acetyl)-${\beta}$-D-allopyranosyl(1${\rightarrow}$2)-${\beta}$-D-glucopyranoside (3), and isoscutellarein 7-O-${\beta}$-D-allopyranosyl(1${\rightarrow}$2)-${\beta}$-D-glucopyranoside (4) in addition to a flavonol glycoside, kaempferol 3-O-${\beta}$-D-glucopyranoside (astragalin, 2), were isolated from Stachys japonica (Lamiaceae). In cholinesterase inhibition assay, compound 1 significantly inhibited aceylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities ($IC_{50}s$, $39.94{\mu}g/ml$ for AChE and $86.98{\mu}g/ml$ for BChE). The content of isolated compounds were evaluated in this plant extract by HPLC analysis. Our experimental results suggest that the flavonoid glycosides of S. japonica could prevent the memory impairment of Alzheimer's disease.

• BMB Reports
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• v.55 no.7
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• pp.342-347
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• 2022

Defense priming allows plants to enhance their immune responses to subsequent pathogen challenges. Recent reports suggested that acquired resistances in parental generation can be inherited into descendants. Although epigenetic mechanisms are plausible tools enabling the transmission of information or phenotypic traits induced by environmental cues across generations, the mechanism for the transgenerational inheritance of defense priming in plants has yet to be elucidated. With the initial aim to elucidate an epigenetic mechanism for the defense priming in plants, we reassessed the transgenerational inheritance of plant defense, however, could not observe any evidence supporting it. By using the same dipping method with previous reports, Arabidopsis was exposed repeatedly to Pseudomonas syringae pv tomato DC3000 (Pst DC3000) during vegetative or reproductive stages. Irrespective of the developmental stages of parental plants that received pathogen infection, the descendants did not exhibit primed resistance phenotypes, defense marker gene (PR1) expression, or elevated histone acetylation within PR1 chromatin. In assays using the pressure-infiltration method for infection, we obtained the same results as above. Thus, our results suggest that the previous observations on the transgenerational inheritance of defense priming in plants should be more extensively and carefully reassessed.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.10
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• pp.2701-2717
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• 2023

In this paper, a hybrid fuzzy-based method is suggested for determining India's best system for power generation. This suggested approach was created using a fuzzy-based combination of the Giza Pyramids Construction (GPC) and Recalling-Enhanced Recurrent Neural Network (RERNN). GPC is a meta-heuristic algorithm that deals with solutions for many groups of problems, whereas RERNN has selective memory properties. The evaluation of the current load requirements and production profile information system is the main objective of the suggested method. The Central Electricity Authority database, the Indian National Load Dispatch Centre, regional load dispatching centers, and annual reports of India were some of the sources used to compile the data regarding profiles of electricity loads, capacity factors, power plant generation, and transmission limits. The RERNN approach makes advantage of the ability to analyze the ideal power generation from energy data, however the optimization of RERNN factor necessitates the employment of a GPC technique. The proposed method was tested using MATLAB, and the findings indicate that it is effective in terms of accuracy, feasibility, and computing efficiency. The suggested hybrid system outperformed conventional models, achieving the top result of 93% accuracy with a shorter computation time of 6814 seconds.

• Journal of Ginseng Research
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• v.48 no.1
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• pp.98-102
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• 2024

Background: Ginseng (Panax ginseng Meyer) is a perennial plant belonging to the Araliaceae family that is known to have various beneficial effects including improving memory loss and spatial cognitive ability, and anti-cancer and anti-diabetes activity. Its functional benefits also include improving liver function, regulating blood pressure, stress, and providing antioxidant activity. Usually, various agrochemicals are used in cultivating ginseng preventing from many diseases. Methods: FCGP (field cultivated ginseng in pot) was implemented by imitating MCWG (mountain cultivated wild ginseng). Pesticide analysis of pot cultivation was carried out and the contents of bioactive components such as ginsenoside were also analyzed. Results: FCGP ginsenoside content was higher than that of FCG (field cultivated ginseng) and MCWG. FCGP has been shown to have a relatively high antioxidant effect compared with cultivated ginseng. Conclusion: It was confirmed that ginseng can be grown for 6 years without resorting to use of pesticides. In addition, it was confirmed that effective accumulation of physiologically active ingredients such as ginsenoside is possible. Our result represents FCGP is a novel method of pesticide-free ginseng cultivation

• Nuclear Engineering and Technology
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• v.56 no.5
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• pp.1725-1732
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• 2024

In nuclear power plants, reactor coolant leakage can occur due to various reasons. Early detection of leaks is crucial for maintaining the safety of nuclear power plants. Currently, a detection system is being developed in Korea to identify reactor coolant system (RCS) leakage of less than 0.5 gpm. Typically, RCS leaks are detected by monitoring temperature, humidity, and radioactivity in the containment, and a water level in the sump. However, detecting small leaks proves challenging because the resulting changes in the containment humidity and temperature, and the sump water level are minimal. To address these issues and improve leak detection speed, it is necessary to quantify the leaks and develop an artificial intelligence-based leak detection system. In this study, we employed bidirectional long short-term memory, which are types of neural networks used in artificial intelligence, to predict the relative humidity in the leakage area for leak quantification. Additionally, an optimization technique was implemented to reduce learning time and enhance prediction performance. Through evaluation of the developed artificial intelligence model's prediction accuracy, we expect it to be valuable for future leak detection systems by accurately predicting the relative humidity in a leakage area.

• The Journal of Art Theory & Practice
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• no.13
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• pp.35-71
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• 2012

The purpose of this essay is to examine the responses of artists on nuclear experiences through an analysis of the nuclear images represented in contemporary Japanese art. Japan has previously as twice experienced nuclear disaster in 20th century. The first atomic bombs were dropped in 1945 as well as the 5th Fukuryumaru, Japanese pelagic fishing boat, exposed by hydrogen bomb test operated by the US in 1954 nearby Bikini atoll. Due to Tsunami taken place by the great earthquake that caused the meltdown of Fukushima Nuclear Power Plant in March 2010, Japan is being experienced a nuclear disaster again. Despite practical experiences, comtemporary Japanese art has avoided the subject of nuclear disasters since the end of the Asia-Pacific War for a variety of reasons. Firstly, GHQ prohibited to record or depict the terrible effect of atomic bomb until 1946. Secondly, Japanese government has tried to sweep the affair under the carpet quite a while a fact of nuclear damage to their people. Because Japan has produced numerous war record paintings during the Second World War, in the aftermath of the defeated war, most of Japanese artists thought that dealing with politics, economics, and social subject was irrelevant to art as well as style of amateur in order to erase their melancholic memory on it. In addition, silence that was intended to inhibit victims of nuclear disasters from being provoked psychologically has continued the oblivion on nuclear disasters. For these reasons, to speak on nuclear bombs has been a kind of taboo in Japan. However, shortly after the atomic bomb dropped on Hiroshima, the artist couple Iri and Toshi Maruki visited to ruin site as a volunteer for Victim Relief. They portrayed the horrible scenes of the legacy of nuclear bomb since 1950 based on their observation. Under the condition of rapid economical growth in 1960s and 1970s, Japanese subculture such as comics, TV animations, plastic model, and games produced a variety of post apocalyptic images recalling the war between the USA and Japanese militarism, and battle simulation based on nuclear energy. While having grown up watching subculture emerged as Japan Neo-Pop in 1990s, New generation appreciate atomic images such as mushroom cloud which symbolizes atomic bomb of Hiroshima. Takashi Murakami and other Neo-Pop artists appropriate mushroom cloud image in their work. Murakami curated three exhibitions including and persists in superflat and infantilism as an evidence in order to analyze contemporary Japanese society. However, his concept, which is based on atomic bomb radiation exposure experience only claimed on damage and sacrifice, does not reflect Japan as the harmer. Japan has been constructing nuclear power plants since 1954 in the same year when the 5th Fukuryumaru has exposed until the meltdown of Fukushima Nuclear Plant although took place of nuclear radiation exposures of Three Mile and Chernobyl. Due to the exploding of Fukushima Nuclear Power Plant, Japan reconsiders the danger of nuclear disaster. In conclusion, the purpose of this paper may be found that the sense of victim which flowed in contemporary art is able to inquire into the response of artist on the subject of nuclear as well as the relationship between society, politics, culture, and modern history of Japan and international political situation.

• Journal of Korean Society of Disaster and Security
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• v.13 no.4
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• pp.75-92
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• 2020

In most cases of the water balance analysis, the return flow ratio for each water supply was uniformly determined and applied, so it has been contained a problem that the volume of available water would be incorrectly calculated. Therefore, sewage and wastewater among the return water were focused in this study and the data-driven model was developed to forecast the outflow from the sewage treatment plant. The forecasting results of LSTM (Long Short-Term Memory), GRU (Gated Recurrent Units), and SVR (Support Vector Regression) models, which are mainly used for forecasting the time series data in most fields, were compared with the observed data to determine the optimal model parameters for forecasting outflow. As a result of applying the model, the root mean square error (RMSE) of the GRU model was smaller than those of the LSTM and SVR models, and the Nash-Sutcliffe coefficient (NSE) was higher than those of others. Thus, it was judged that the GRU model could be the optimal model for forecasting the outflow in sewage treatment plants. However, the forecasting outflow tends to be underestimated and overestimated in extreme sections. Therefore, the additional data for extreme events and reducing the minimum time unit of input data were necessary to enhance the accuracy of forecasting. If the water use of the target site was reviewed and the additional parameters that could reflect seasonal effects were considered, more accurate outflow could be forecasted to be ready for climate variability in near future. And it is expected to use as fundamental resources for establishing a reasonable river water management system based on the forecasting results.

• Journal of Ginseng Research
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• v.47 no.4
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• pp.561-571
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• 2023

Background: Escalating evidence shows that ginseng possesses an antiaging potential with cognitive enhancing activity. As mountain cultivated ginseng (MCG) is cultivated without agricultural chemicals, MCG has emerged as a popular herb medicine. However, little is known about the MCG-mediated pharmacological mechanism on brain aging. Methods: As we demonstrated that glutathione peroxidase (GPx) is important for enhancing memory function in the animal model of aging, we investigated the role of MCG as a GPx inducer using GPx-1 (a major type of GPx) knockout (KO) mice. We assessed whether MCG modulates redox and cholinergic parameters, and memory function in aged GPx-1 knockout KOmice. Results: Redox burden of aged GPx-1 KO mice was more evident than that of aged wild-type (WT) mice. Alteration of Nrf2 DNA binding activity appeared to be more evident than that of NFκB DNA binding activity in aged GPx-1 KO mice. Alteration in choline acetyltransferase (ChAT) activity was more evident than that in acetylcholine esterase activity. MCG significantly attenuated reductions in Nrf2 system and ChAT level. MCG significantly enhanced the co-localization of Nrf2-immunoreactivity and ChAT-immunoreactivity in the same cell population. Nrf2 inhibitor brusatol significantly counteracted MCG-mediated up-regulation in ChAT level and ChAT inhibition (by k252a) significantly reduced ERK phosphorylation by MCG, suggesting that MCG might require signal cascade of Nrf2/ChAT/ERK to enhance cognition. Conclusion: GPx-1 depletion might be a prerequisite for cognitive impairment in aged animals. MCG-mediated cognition enhancement might be associated with the activations of Nrf2, ChAT, and ERK signaling cascade.

• Journal of Korean Society of Forest Science
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• v.31 no.1
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• pp.53-61
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• 1976

Though it is not easy for those who study dendrology to memorize all the scientific names of trees, the names remaines in their memory can facilitate the understanding of foreign technical books. The scientific name of a tree indicates characteristics of shape, color, and other aspects of the tree and by analyzing the name we can see common element found in other scientific names of trees. It is helpful to those who want to memorize and study the scientific names of trees if they understand their etymology. The preseut study is the seconds report of the investigation which aims at examining the etymology of the scientific names of native and foreign trees growing in Korea and their original names not only at the habitat but in Japan, China, England, Germany, and France. While the first report, which was made known in Theses Vol. 9. (The City College of Seoul 1975), is the examination of the scientific names of trees belonging to Gymnospermae, the present report is that of scientific names of trees belonging to Piperales: 2 families, 2 genera and 2 species; and trees belonging to Salicales: 1 family, 3 genera, 44 species, 16 varieties, and 3 forms. As the etymology of the scientific names of trees is made clear, this study will help those who want memorize the scientific names and study foreign technical books and it is also useful for international interchange of trees. The classification is depended chiefly on Dendrology by Prof. Lee Tchang-bok and "Plant Resources of Korea" shown in Biblography No. 10; the native names of trees on Jumoku Daizusetsu by Dr. Uehara; and etymology on A source-Book of Biological Names and Terms by E.C. Jager. In the column of etymology of the scientific names for genera, species, varieties and forms, Gr. stands for Greek, L. for Latin, NL. for New Latin, and genit. for genitive.

• Journal of Ginseng Research
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• v.44 no.4
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• pp.527-537
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• 2020

Panax ginseng, a medicinal plant, has been used as a blood-nourishing tonic for thousands of years in Asia, including Korea and China. P. ginseng exhibits adaptogen activity that maintains homeostasis by restoring general biological functions and non-specifically enhancing the body's resistance to external stress. Several P. ginseng effects have been reported. Korean Red Ginseng, in particular, has been reported in both basic and clinical studies to possess diverse effects such as enhanced immunity, fatigue relief, memory, blood circulation, and anti-oxidation. Moreover, it also protects against menopausal symptoms, cancer, cardiac diseases, and neurological disorders. The active components found in most Korean Red Ginseng varieties are known to include ginsenosides, polysaccharides, peptides, alkaloids, polyacetylene, and phenolic compounds. In this review, the identity and bioactivity of the non-saponin components of Korean Red Ginseng discovered to date are evaluated and the components are classified into polysaccharide and nitrogen compounds (protein, peptide, amino acid, nucleic acid, and alkaloid), as well as fat-soluble components such as polyacetylene, phenols, essential oils, and phytosterols. The distinct bioactivity of Korean Red Ginseng was found to originate from both saponin and non-saponin components rather than from only one or two specific components. Therefore, it is important to consider saponin and non-saponin elements together.