• Journal of the Computational Structural Engineering Institute of Korea
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• v.24 no.3
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• pp.329-335
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• 2011

The finite element method (FEM) has been used for various fields like mathematics and engineering. However, the FEM has a difficulty in describing the geometric shape exactly due to its property of piecewise linear discretization. Recently, however, a so-called isogeometric analysis method that uses the non-uniform rational B-spline(NURBS) basis function has been developed. The NURBS can be used to describe the geometry exactly and play a role of basis functions for the response analysis. Nevertheless, constructing the NURBS basis functions in analysis is as costly as a meshing process in the FEM. Since the isogeometric method shares geometric data with CAD, it is possible to intactly import the model data from commercial CAD tools. In this paper, we use the Rhinoceros 3D software to create CAD models and export in the form of STEP file. The information of knot vectors and control points in the NURBS is utilized in the isogeometric analysis. Through some numerical examples, the accuracy of isogeometric method is compared with that of FEM. Also, the efficiency of the isogeometric method that includes the CAD and CAE in a unified framework is verified.

• Water for future
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• v.13 no.2
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• pp.35-47
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• 1980

An algorithm is developed to derive a representative I hr-unit hydrograph through an analysis of rainfall-runoff relations of a watershed as a closed system. For the base flow seperation of a flood hydrograph the multi-deflection method is proposed herein, which gace better results compared with those by the existing empirical methods. A modified $\Phi$index method is also proposed in this stidy to determine the time distribution rainfall excess of a rainstorm, which is essetially a modification of the commonly used $\Phi$index method of rainfall seperation. With the so-obtained rainfall excess hyetograph and the direct runoff hydrograph a trial and error computation of the ordinates of 1 hr-unit hydrograph was executed in such a manner that the synthesized flood hydrograph closely approximates the observed one, thus resulting a unit hydrograph of a piecewise exponential function type. To verify the validity of this study the 1 hr-unit hydrographs for the Imha and Dongchon in Nagdong River basin, and Yongdam in Geum River basin were derived by this algorithm, and the results were compared with those by the conventional synthetic unit hydrograph method and the Nakayasu method. Besides, the validity of this stiudy was also tested by comparing the observed hydrograph with the one computed by applying the unit hydrograph to a specific rainfall event. To generalize the result of this study a computer program, consisited of a main and three subprograns (for rainfall excess estimation, convolution summation, and sorting), is developed as a package, which is believed to be applicable to other watersheds for the similar purpose as those in this study.

• Journal of Biomedical Engineering Research
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• v.25 no.3
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• pp.189-194
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• 2004

Pixel values of contrast enhanced computed tomography (CE-CT) images are randomly changed. Also, the middle liver part has a problem to segregate the liver structure because of similar gray-level values of a pancreas in the abdomen. In this paper, an automatic liver segmentation method using a partial histogram threshold (PHT) algorithm is proposed for overcoming randomness of CE-CT images and removing the pancreas. After histogram transformation, adaptive multi-modal threshold is used to find the range of gray-level values of the liver structure. Also, the PHT algorithm is performed for removing the pancreas. Then, morphological filtering is processed for removing of unnecessary objects and smoothing of the boundary. Four CE-CT slices of eight patients were selected to evaluate the proposed method. As the average of normalized average area of the automatic segmented method II (ASM II) using the PHT and manual segmented method (MSM) are 0.1671 and 0.1711, these two method shows very small differences. Also, the average area error rate between the ASM II and MSM is 6.8339 ％. From the results of experiments, the proposed method has similar performance as the MSM by medical Doctor.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.27 no.5
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• pp.437-450
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• 2014

In this study, we developed a methodology to determine the reference parameter for an aircraft impact induced risk assessment of nuclear power plant (NPP) using finite element impact analysis of containment building. The target structure used to develop the method of reference parameter selection is one of the typical Korean PWR type containment buildings. We composed a three-dimensional finite element model of the containment building. The concrete damaged plasticity model was used for the concrete material model. The steels in the tendon, rebar, and liner were modeled using the piecewise-linear stress-strain curves. To evaluate the correlations between structural response and each candidate parameter, we developed Riera's aircraft impact force-time history function with respect to the variation of the loading parameters, i.e., impact velocity and mass of the remaining fuel. For each force-time history, the type of aircraft is assumed to be a Boeing 767 model. The variation ranges of the impact velocity and remaining fuel percentage are 50 to 200m/s, and 30 to 90%, respectively. Four parameters, i.e., kinetic energy, total impulse, maximum impulse, and maximum force are proposed for candidates of the reference parameter. The wellness of the correlation between the reference parameter and structural responses was formulated using the coefficient of determination ($R^2$). From the results, we found that the maximum force showed the highest $R^2$ value in most responses in the materials. The simplicity and intuitiveness of the maximum force parameter are also remarkable compared to the other candidate parameters. Therefore, it can be concluded that the maximum force is the most proper candidate for the reference parameter to assess the aircraft impact induced risk of NPPs.

• Journal of Preventive Medicine and Public Health
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• v.46 no.1
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• pp.19-27
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• 2013

Objectives: This study was conducted to investigate the relationship between heat-related illnesses developed in the summer of 2012 and temperature. Methods: The study analyzed data generated by a heat wave surveillance system operated by the Korea Centers for Disease Control and Prevention during the summer of 2012. The daily maximum temperature, average temperature, and maximum heat index were compared to identify the most suitable index for this study. A piecewise linear model was used to identify the threshold temperature and the relative risk (RR) above the threshold temperature according to patient characteristics and region. Results: The total number of patients during the 3 months was 975. Of the three temperature indicators, the daily maximum temperature showed the best goodness of fit with the model. The RR of the total patient incidence was 1.691 (1.641 to 1.743) per $1^{\circ}C$ after $31.2^{\circ}C$. The RR above the threshold temperature of women (1.822, 1.716 to 1.934) was greater than that of men (1.643, 1.587 to 1.701). The threshold temperature was the lowest in the age group of 20 to 64 ($30.4^{\circ}C$), and the RR was the highest in the ${\geq}65$ age group (1.863, 1.755 to 1.978). The threshold temperature of the provinces ($30.5^{\circ}C$) was lower than that of the metropolitan cities ($32.2^{\circ}C$). Metropolitan cities at higher latitudes had a greater RR than other cities at lower latitudes. Conclusions: The influences of temperature on heat-related illnesses vary according to gender, age, and region. A surveillance system and public health program should reflect these factors in their implementation.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.13 no.2
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• pp.111-119
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• 2013

Purpose: Mucopolysaccharidosis type I (MPS I) is a lysosomal storage disorder caused by deficiency of the enzyme ${\alpha}$-L-iduronidase, which leads to a broad spectrum of multisystemic manifestations. Short stature and decreased growth velocity are prominent features of MPS I. The aim of the present study was to evaluate the effect of enzyme replacement therapy (ERT) on growth of Korean MPS I patients from a single center. Methods: Height data were obtained by retrospective chart review of 10 Korean patients with MPS I who had received ERT for a minimum of 3 years. Height was expressed as standard deviation scores (SDS) based on normative data. Annual growth rates were calculated before and during ERT. A piecewise regression model was used to analyze height z-scores before and after treatment. Individual analysis was performed for impact of phenotype [(severe (Hurler) versus attenuated (Hurler-Scheie, Scheie)] on growth. Results: Annual growth was 3.3 cm (z-score= -0.21) in the year before ERT and 6.2 cm (z-score= 0.17), 5.8 cm (z-score= 0.07), and 3.8 cm (z-score= -0.4) in the first, second, and third years of ERT, respectively. Regression analysis showed improvement in the slope after ERT (difference= 0.04; P=0.022). Estimated slope differences between severe and attenuated phenotypes were statistically significant before (P=0.001) and after treatment (P<0.0001), although no significant difference was noted when stratified by phenotype. Conclusion: ERT with aldurazyme appears to have a positive impact on linear growth in patients with MPS I.