• 식물병연구
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• 제11권2호
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• pp.122-127
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• 2005

Late blight of potato caused by Phtophthora infestans is one of the most destructive disease in organic farming as well as in the conventional cultivation in Korea. Incidence and progress of the disease largely depend on climatic conditions around the fields. However, the disease completely destroys whole leaves of the plant within two weeks in organic farming fields. While, potato leaves in conventional farming fields remain healthy for 5 weeks after the first symptom appearance, because fungicides were applied four times in average to control the disease. Area under disease progress curve (AUDPC) of organic farming fields ranged from 2314 to 2421 and quickly expanded compare to that of conventional farming fields. The tuber yield in the organic farming fields ranged from 0.96 ton per 10a to 1.5 ton per 10a, while it was 2.7 ton per 10a in conventional farming fields. Tuber yields were reduced to $42\~63\%$ by the infection of late blight and the reduction rate was closely related with the time of first occurrence of the disease in organic farming fields. Physiological races of the pathogen were diversified with R0,1,3,4,5,7,10,11 in organic farming fields at Hongchun area. Pathogen races were distributed with similar pattern at different areas of organic farming fields.

• 동의생리병리학회지
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• 제24권6호
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• pp.1094-1098
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• 2010

With the high prevalence of functional dyspepsia in the world, it was difficult to get objective diagnosis, treatment and assessment for the reason that there were many different symptoms and signs. The purpose of this study is to develop a standard instrument of pattern identification for functional dyspepsia which will be applied to clinical research. The items and structure of the instrument were based on review of published literature. The advisor committee on this study was organized by 11 oriental division of gastroenterology professors of oriental medical colleges nationwide. The experts discussed developing the instrument, and we also took professional advices by e-mail. We divided the symptoms and signs of functional dyspepsia into 6 pattern identification, such as disharmony of liver and stomach, retention of undigested food, damp-heat in the spleen and stomach, simultaneous occurrence of cold and heat syndromes, deficiency and cold of the spleen and the stomach, and insufficiency of stomach eum. We got the mean weights to each symptom of six pattern identification which had been scored on a 5-point scale ranging from 1 to 5 by the 11 experts. We made out the Korean instrument of the pattern identification composed of 45 questions for functional dyspepsia. Although there are some limitations in our study, the instrument is meaningful and certain worth of its own. We hope to improve the instrument through the further clinical studies and discussions.

• 수면정신생리
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• 제2권2호
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• pp.146-155
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• 1995

Jet lag can be defined as the cumulative physiological and psychological effects of rapid air travel across multiple time zone. The consequences of jet lag include fatigue, general malaise, sleep disturbances, and reductions of cognitive and psychomotor performance, all of which have been documented in experimental biological and air crew personnel studies. Thus authors tried to study the jet lag of natural travellers by modified self reporting sleep log. Total 61 healthy travellers was studied for 3 days before and 7 days after jet-flights across seven to ten time zone. The eastbound travelling group was 38 persons, aged 19 -70 and westbound travelling group was 23 persons, aged 13 - 69. Sleep onset time, wake-up time, sleep latency, awakening frequency on night sleep, awakening duration on night sleep, sleepiness at wake-up and nap length were evaluated. Our results suggested that the 7 to 10 time zone shift gave significant influence to traveller's sleep-wake cycles. The date which subjective physical condition was recovered on was $5.16{\pm}1.50$ day after arrivals for eastbound, while for westbound, $4.91{\pm}1.62$ day. In eastbound travelling, sleep onset time became later than baselines and could not recover until 7th day. But in westbound, it became earlier than baseline and could recover until 6th day. The mean score of 24-hour sleepiness was greater in eastboumd than westbound. Therefore the eastbound travelling caused more sleep-wake cycle disturbance and daytime dysfunction than westbound travelling. In other parameters, there was no definite difference between east and westbound. From our results, it was suggested that the symptom severity of jet lag was dependent on the travelling direction. To demonstrate more definite evidence, large sized data collections and comparision by age difference were needed.

• 한국응용곤충학회지
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• 제41권4호
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• pp.279-284
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• 2002

누에(Bombyx mori) 5령 유충에서 무름병 증상이 발견되었다. 세균성 병원균이 감염 누에 혈액에서 분리되었고, 본 연구에서 동정되었다. 분리된 세균을 각각의 누에 5령 유충에 $5{\times}10^{6}$ cfu(colony-forming unit) 농도로 혈강 주사되었을 때, 뚜렷한 무름병 증상을 유발시켰다. 이렇게 감염된 유충들은 접종 6일 후부터 죽기 시작하여, 10일 경과 후 처리된 유충 모두 사망하였다. Bergey의 세균동정집에 기록된 형태적 및 생리적 형질을 기준으로 이 곤충병원세균이 Staphylo-coccue gallinarum으로 판명되었다. 이 판정은 탄소원 분석 미생물동정장치($MicroLog^{\circledR}$) 분석 결과와 16S-23S rDNA internal transcribed space 구조에 의해서 확인되었다. 이 세균이 발휘하는 살충기작의 일환으로서, 감염 후 누에 유충 혈구에 세포치사 효과를 주어 패혈증을 유발하는 것으로 분석되었다.

• 사상체질의학회지
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• 제31권4호
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• pp.9-17
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• 2019

Objectives The purpose of this study is to understand the intention expressed as Jeubjeubhanchul(濈濈汗出) unlike the aspect of perspiration in 『Sanghanlun(傷寒論)』 and 『Donguibogam(東醫寶鑑)』. Methods We examined Sibjo-tang(十棗湯) and the aspect of perspiration focusing on the Chip(漐) and Jeub(濈) in 『Sanghanlun(傷寒論)』, 『Donguibogam(東醫寶鑑)』, and 『Donguisusebowon(東醫壽世保元)』. Moreover, we examined the connection between the quoted purpose of Sibjo-tang and the aspect of perspiration. Results and Conclusion 1. When Leejema quoted Sibjo-tang to explain the Chestbind disease(結胸) of the Soyang pattern, he used Jeubjeubhanchul (濈濈汗出) instead of Chipchiphanchul(漐漐汗出). 2. About the aspect of perspiration in 『Sanghanlun』 and 『Donguibogam』, the Chip(漐) is used in a situation when the disease progressed from Pyo(表) to Li(裏) and Taeyang-byeong(太陽病) to Yangmyung-byeong(陽明病), and it is expression of physiological perspiration. The Jeub(濈) is used in a situation related to interior(內), Li(裏), and Yangmyung-byeong. 3. Leejema understood Sibjo-tang in relation to the Chestbind disease of the Soyang pattern caused by aggravation of Liyeol (裏熱). Therefore, Leejema used the Jeub(濈) related to interior, Li and Yangmyung-byeong, and it is expression of perspiration caused by aggravation of Liyeol in the Soyang pattern. 4. At first time, Leejema mentioned perspiration and short of breath(短氣) in the symptoms of Sibjo-tang, but he mentioned dry vomiting(乾嘔) and short of breath in 『Sinchukbon(辛丑本)』. Thus, his perspective of perspiration related to Sibjo-tang was appeared in 『Gabobon(甲午本)』, and he paid attention to perspiraion as a major symptom of the Chestbind disease in the early. After clinical experience was built up, It was not that important as the past.

• 혜화의학회지
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• 제9권1호
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• pp.121-134
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• 2000

The following results obtained through studies related on nose. 1. Nose is called mingtang(明堂) mianwang(面王), as it emphasize the meaning of viewing diagnosis(望診) and is called yuanpinzhimen(元牝之門), tianpinzhimen(天牝之門), qiqizhimen(七氣之門) as it emphasize the meaning of the entrance of atmosphere flow. Because it's position is the middle of face, we call tianzhongzhiyue(天中之嶽), zhongyue(中嶽). 2. As the organ of body, nose comes under the category of lung-iron(肺金), functionally comes under the category of heart-fire(心火). Functionally we can smell oder, organically nose is the pathway of respiration and to be resonator. 3. Wuzangliufu(五臟六腑) is arranged closely around the nose. The essence of wuzangliufu(五臟六腑) reflect nose, so nose becomes the standard of coloring diagnosis(色診). 4. We call nose is feihou(肺候), but it is not connected directly between the lung channel and nose. In case of lung symptom(肺證), first of all, nose become to appear the condition of lung, the lung channel and nose is close functionally. 5. The view of channels, nose is a connection with channels of yangming(陽明), bladder(膀胱), du(督脈) directly. By the connecting of each three channels, spleen stomach heart and kidney(脾胃心腎) are connected with indirectly. As the result of the relation, nose helps for body to breathe and to circulate qi(氣) and smell. And so the nature of wuzangliufu(五臟六腑) appear to the nose. 6. Particularly, the yangming channel(陽明經), and the bladder channel(膀胱經) are important. Because air-qi(天氣) reach to kidney lung through nose, ground-qi(地氣) reach to spleen stomach through mouth and yingwei(營衛) revolve through the bladder channel(膀胱經). As the result nose becomes the essential organ of circulation of yinewei(營衛), ascent and descent of qi(氣).

• 대한간호학회지
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• 제48권2호
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• pp.208-220
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• 2018

Purpose: The aim of this study was to analyze the effects of neurofeedback training for reducing stress and enhancing self-regulation in late adolescence to identify the possibility of use for nursing intervention. Methods: A nonequivalent control group pre-post quasi-experimental design was used. Participants were 78 late adolescents assigned to the experimental group (n=39) that received the neurofeedback training and the control group (n=39). Data were collected on heart rate variability (HRV) and skin conductance level (SCL) to assess stress-biomarker response. The questionnaire contained 164 items from: Positive and Negative Affect Schedule (PANAS), Symptom Checklist-90-Revised (SCL-90-R) and Self-regulatory Ability scale. The neurofeedback training was based on the general adaptation syndrome and body-mind medicine. The intervention was conducted in a total of 10 sessions for 30 minutes per session with high-beta, theta and sensory motor rhythm training on scalp at central zero. Results: There were significant difference in standard deviation of normal to normal interval (p=.036) in HRV and SCL (p=.029) of stress-biomarker response between the two groups. Negative affect (p=.036) in PANAS and obsessive compulsive (p=.023) and depression (p<.001) in SCL-90-R were statistically significant. Self-regulation mode (p=.004) in self-regulation ability scale showed a significant difference between the two groups. Conclusion: The results indicated that the neurofeedback training is effective in stress-biomarkers, psychoemotional stress response and self-regulation. Therefore, neurofeedback training using neuroscientific approach based on brain-mind-body model can be used as an effective nursing intervention for late adolescents in clinics and communities for effective stress responses.

• 생명과학회지
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• 제21권9호
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• pp.1295-1300
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• 2011

식물체에서 당 조절 인자의 병 저항성 생리적 특성을 살펴보길 위하여, 원형질막에 존재하는 glucose 조절인자인 애기장대 AtPGR 유전자의 과발현 및 RNAi 형질전환체를 사용하였다[3]. AtPGR 유전자는 병원균 처리에 의하여 전사 발현양이 증가하였을 뿐만 아니라, JA와 SA 처리 시에도 AtPGR 전사 발현양이 증가함을 확인하였다. 과발현 형질전환체를 이용하여 병 저항성을 살펴본 결과, AtPGR 유전자는 병원균에 대해 저항성을 유도함을 알수 있었다. 또한 병원균 유도 증가 유전자로 알려진 PDF1.2 및 PR1 유전자 발현 양상을 qPCR을 통해 살펴본 결과, AtPGR 유전자는 PDF1.2 유전자를 SA 경로 하에서는 증가시키는 반면, JA 경로 하에서는 발현 증가량을 감소시키는 경향이 있음을 나타내었고, PR1 유전자의 발현은 JA 경로를 통해 조절할 것으로 생각되어진다. 이러한 결과를 바탕으로, AtPGR 유전자는 glucose 뿐만 아니라 병원균 반응에도 관련되어져 있음을 알 수 있다.

• 동의생리병리학회지
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• 제26권6호
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• pp.812-817
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• 2012

In "The region of the body in which abdomen pain manifests(腹痛有部分)" of "Dongeuibogam(東醫寶鑑)", the abdomen is divided into the upper abdomen(大腹), umbilicus area(臍腹) and lower abdomen(小腹), which are in turn assigned to 3 Yins of greater yin(太陰), lesser yin(少陰) and reverting yin(厥陰) respectively to explain the causes and treatments of abdomen pain according to their locations. Meanwhile, the present Korean medicine tends to issue herbal formula without considering the cause of regional abdomen pain and the aspect of cold and heat(寒熱), deficiency and excess(虛實) in the symptom. This fragmentary treatment may bring out a serious failure. For the correction of this problem, the literature study on "The region of the body in which abdomen pain manifests(腹痛有部 分)" of "Dongeuibogam(東醫寶鑑)" was carried out to obtain the following conclusions. In "The region of the body in which abdomen pain manifest (腹痛有部分)" of "Dongeuibogam(東醫寶鑑)", it turned out that the use of herbal formula for the abdomen pain was the integrated one of herbal formulas for the abdomen pain in the external contraction such as cold damage yin condition(傷寒陰證) and cold in the middle condition(中寒證) and that the cause of abdomen pain was the explanation of diverse internal causes for the abdomen pain. And it was also found that the assignment of the upper abdomen(大腹), umbilicus area(臍腹) and lower abdomen(小腹) to 3 Yins had the locational and meridian meanings of 3 Yins according to internal causes and external contraction to get the basis of abdomen pain treatment in dividing it into 3 Yins.

• 동의생리병리학회지
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• 제25권1호
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• pp.8-18
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• 2011

To have effective treatment for shoulder arm pain, we searched the cause, symptom, etiology, classification of the pain areas, acupuncture points, and muscles along the meridians, and acquired the following results. Shoulder-pain is mainly divided into the malfunction of viscera and entrails, damage due to the weakness of essence and qi, abnormal status of muscle function, change of joints, disease in the nerve and vessel, and the internal injury due to seven modes of emotions. Pain of shoulder joints are pain in the local area of shoulder joints, referred pain of shoulder, neck, and shoulder-arm, numbnes and swelling of muscle, and muslce weakness. Shoulder-arm pain is classified as four types of pain: shoulder-joint pain, shoulder-back pain, shoulder-chest pain, and shoulder-arm-elbow pain. And shoulder-arm-elbow pain is again divided into the shoulder-blade pain, shoulder-arm pain, shoulder-elbow pain. The related meridians on shoulder pain are the three yin meridians of hand, Kidney Meridian, Conception Meridian, three yang meridians of hand, Bladder Meridian, Governor Meridian Acupuncture points for shoulder pain are in the acupuncture points of the 10 meridians and a-shi points. Thre related meridian muscles on shoulder-pain are the three yin and yang meridians of hand, and their related muscles are the ones that are connected with the front, back, and chest side muscles of shoulder joints, and the ones that are connected with the front and back side muscles of arm.