• Research in Plant Disease
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• v.11 no.2
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• pp.122-127
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• 2005

Late blight of potato caused by Phtophthora infestans is one of the most destructive disease in organic farming as well as in the conventional cultivation in Korea. Incidence and progress of the disease largely depend on climatic conditions around the fields. However, the disease completely destroys whole leaves of the plant within two weeks in organic farming fields. While, potato leaves in conventional farming fields remain healthy for 5 weeks after the first symptom appearance, because fungicides were applied four times in average to control the disease. Area under disease progress curve (AUDPC) of organic farming fields ranged from 2314 to 2421 and quickly expanded compare to that of conventional farming fields. The tuber yield in the organic farming fields ranged from 0.96 ton per 10a to 1.5 ton per 10a, while it was 2.7 ton per 10a in conventional farming fields. Tuber yields were reduced to $42\~63\%$ by the infection of late blight and the reduction rate was closely related with the time of first occurrence of the disease in organic farming fields. Physiological races of the pathogen were diversified with R0,1,3,4,5,7,10,11 in organic farming fields at Hongchun area. Pathogen races were distributed with similar pattern at different areas of organic farming fields.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.6
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• pp.1094-1098
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• 2010

With the high prevalence of functional dyspepsia in the world, it was difficult to get objective diagnosis, treatment and assessment for the reason that there were many different symptoms and signs. The purpose of this study is to develop a standard instrument of pattern identification for functional dyspepsia which will be applied to clinical research. The items and structure of the instrument were based on review of published literature. The advisor committee on this study was organized by 11 oriental division of gastroenterology professors of oriental medical colleges nationwide. The experts discussed developing the instrument, and we also took professional advices by e-mail. We divided the symptoms and signs of functional dyspepsia into 6 pattern identification, such as disharmony of liver and stomach, retention of undigested food, damp-heat in the spleen and stomach, simultaneous occurrence of cold and heat syndromes, deficiency and cold of the spleen and the stomach, and insufficiency of stomach eum. We got the mean weights to each symptom of six pattern identification which had been scored on a 5-point scale ranging from 1 to 5 by the 11 experts. We made out the Korean instrument of the pattern identification composed of 45 questions for functional dyspepsia. Although there are some limitations in our study, the instrument is meaningful and certain worth of its own. We hope to improve the instrument through the further clinical studies and discussions.

• Sleep Medicine and Psychophysiology
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• v.2 no.2
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• pp.146-155
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• 1995

Jet lag can be defined as the cumulative physiological and psychological effects of rapid air travel across multiple time zone. The consequences of jet lag include fatigue, general malaise, sleep disturbances, and reductions of cognitive and psychomotor performance, all of which have been documented in experimental biological and air crew personnel studies. Thus authors tried to study the jet lag of natural travellers by modified self reporting sleep log. Total 61 healthy travellers was studied for 3 days before and 7 days after jet-flights across seven to ten time zone. The eastbound travelling group was 38 persons, aged 19 -70 and westbound travelling group was 23 persons, aged 13 - 69. Sleep onset time, wake-up time, sleep latency, awakening frequency on night sleep, awakening duration on night sleep, sleepiness at wake-up and nap length were evaluated. Our results suggested that the 7 to 10 time zone shift gave significant influence to traveller's sleep-wake cycles. The date which subjective physical condition was recovered on was $5.16{\pm}1.50$ day after arrivals for eastbound, while for westbound, $4.91{\pm}1.62$ day. In eastbound travelling, sleep onset time became later than baselines and could not recover until 7th day. But in westbound, it became earlier than baseline and could recover until 6th day. The mean score of 24-hour sleepiness was greater in eastboumd than westbound. Therefore the eastbound travelling caused more sleep-wake cycle disturbance and daytime dysfunction than westbound travelling. In other parameters, there was no definite difference between east and westbound. From our results, it was suggested that the symptom severity of jet lag was dependent on the travelling direction. To demonstrate more definite evidence, large sized data collections and comparision by age difference were needed.

• Korean journal of applied entomology
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• v.41 no.4
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• pp.279-284
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• 2002

Flacherie symptom was found in the fifth instar larvae of silkworm, Bombyx mori. The bacterial pathogen was isolated from the hemolymph of the infected silkworm and identified. The isolated bacteria caused a significant flacherie pathogenicity to the fifth instar larvae of B. mori when $5{\times}10^{6}$ cfu (colony-forming unit) of the bacteria was injected into each larva. The infected larvae began to die at 6 days after injection and resulted in complete mortality at 10 days. The bacterium was identified as Staphylococcus gallinarum based on the morphological and physiological characteristics described in Bergey's manual. This identification was further supported by the characters of carbohydrate utility analyzed from a bacterial identification system ($MicroLog^{\circledR}$) and also by the molecular structure of 165-23S rDNA internal transcribed spaces. As an insecticidal action, S. gallinarum caused hemolymph septicemia by its cytotoxic effect on the hemocytes of B. mori.

• Journal of Sasang Constitutional Medicine
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• v.31 no.4
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• pp.9-17
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• 2019

Objectives The purpose of this study is to understand the intention expressed as Jeubjeubhanchul(濈濈汗出) unlike the aspect of perspiration in 『Sanghanlun(傷寒論)』 and 『Donguibogam(東醫寶鑑)』. Methods We examined Sibjo-tang(十棗湯) and the aspect of perspiration focusing on the Chip(漐) and Jeub(濈) in 『Sanghanlun(傷寒論)』, 『Donguibogam(東醫寶鑑)』, and 『Donguisusebowon(東醫壽世保元)』. Moreover, we examined the connection between the quoted purpose of Sibjo-tang and the aspect of perspiration. Results and Conclusion 1. When Leejema quoted Sibjo-tang to explain the Chestbind disease(結胸) of the Soyang pattern, he used Jeubjeubhanchul (濈濈汗出) instead of Chipchiphanchul(漐漐汗出). 2. About the aspect of perspiration in 『Sanghanlun』 and 『Donguibogam』, the Chip(漐) is used in a situation when the disease progressed from Pyo(表) to Li(裏) and Taeyang-byeong(太陽病) to Yangmyung-byeong(陽明病), and it is expression of physiological perspiration. The Jeub(濈) is used in a situation related to interior(內), Li(裏), and Yangmyung-byeong. 3. Leejema understood Sibjo-tang in relation to the Chestbind disease of the Soyang pattern caused by aggravation of Liyeol (裏熱). Therefore, Leejema used the Jeub(濈) related to interior, Li and Yangmyung-byeong, and it is expression of perspiration caused by aggravation of Liyeol in the Soyang pattern. 4. At first time, Leejema mentioned perspiration and short of breath(短氣) in the symptoms of Sibjo-tang, but he mentioned dry vomiting(乾嘔) and short of breath in 『Sinchukbon(辛丑本)』. Thus, his perspective of perspiration related to Sibjo-tang was appeared in 『Gabobon(甲午本)』, and he paid attention to perspiraion as a major symptom of the Chestbind disease in the early. After clinical experience was built up, It was not that important as the past.

• Journal of Haehwa Medicine
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• v.9 no.1
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• pp.121-134
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• 2000

The following results obtained through studies related on nose. 1. Nose is called mingtang(明堂) mianwang(面王), as it emphasize the meaning of viewing diagnosis(望診) and is called yuanpinzhimen(元牝之門), tianpinzhimen(天牝之門), qiqizhimen(七氣之門) as it emphasize the meaning of the entrance of atmosphere flow. Because it's position is the middle of face, we call tianzhongzhiyue(天中之嶽), zhongyue(中嶽). 2. As the organ of body, nose comes under the category of lung-iron(肺金), functionally comes under the category of heart-fire(心火). Functionally we can smell oder, organically nose is the pathway of respiration and to be resonator. 3. Wuzangliufu(五臟六腑) is arranged closely around the nose. The essence of wuzangliufu(五臟六腑) reflect nose, so nose becomes the standard of coloring diagnosis(色診). 4. We call nose is feihou(肺候), but it is not connected directly between the lung channel and nose. In case of lung symptom(肺證), first of all, nose become to appear the condition of lung, the lung channel and nose is close functionally. 5. The view of channels, nose is a connection with channels of yangming(陽明), bladder(膀胱), du(督脈) directly. By the connecting of each three channels, spleen stomach heart and kidney(脾胃心腎) are connected with indirectly. As the result of the relation, nose helps for body to breathe and to circulate qi(氣) and smell. And so the nature of wuzangliufu(五臟六腑) appear to the nose. 6. Particularly, the yangming channel(陽明經), and the bladder channel(膀胱經) are important. Because air-qi(天氣) reach to kidney lung through nose, ground-qi(地氣) reach to spleen stomach through mouth and yingwei(營衛) revolve through the bladder channel(膀胱經). As the result nose becomes the essential organ of circulation of yinewei(營衛), ascent and descent of qi(氣).

• Journal of Korean Academy of Nursing
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• v.48 no.2
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• pp.208-220
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• 2018

Purpose: The aim of this study was to analyze the effects of neurofeedback training for reducing stress and enhancing self-regulation in late adolescence to identify the possibility of use for nursing intervention. Methods: A nonequivalent control group pre-post quasi-experimental design was used. Participants were 78 late adolescents assigned to the experimental group (n=39) that received the neurofeedback training and the control group (n=39). Data were collected on heart rate variability (HRV) and skin conductance level (SCL) to assess stress-biomarker response. The questionnaire contained 164 items from: Positive and Negative Affect Schedule (PANAS), Symptom Checklist-90-Revised (SCL-90-R) and Self-regulatory Ability scale. The neurofeedback training was based on the general adaptation syndrome and body-mind medicine. The intervention was conducted in a total of 10 sessions for 30 minutes per session with high-beta, theta and sensory motor rhythm training on scalp at central zero. Results: There were significant difference in standard deviation of normal to normal interval (p=.036) in HRV and SCL (p=.029) of stress-biomarker response between the two groups. Negative affect (p=.036) in PANAS and obsessive compulsive (p=.023) and depression (p<.001) in SCL-90-R were statistically significant. Self-regulation mode (p=.004) in self-regulation ability scale showed a significant difference between the two groups. Conclusion: The results indicated that the neurofeedback training is effective in stress-biomarkers, psychoemotional stress response and self-regulation. Therefore, neurofeedback training using neuroscientific approach based on brain-mind-body model can be used as an effective nursing intervention for late adolescents in clinics and communities for effective stress responses.

• Journal of Life Science
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• v.21 no.9
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• pp.1295-1300
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• 2011

The AtPGR gene is induced by pathogen infection, jasmonic acid and salicylic acid treatment and may therefore play a role in plant defense responses. Arabidopsis thaliana Plasma membrane Glucose-responsive Regulator (AtPGR) was previously isolated from Arabidopsis, which confers glucose insensitivity on plants. To study its biological functions directly, we have characterized both loss-of-function RNAi mutant and gain-of-function transgenic overexpression plants for AtPGR in Arabidopsis. The AtPGR-overexpressing plants displayed enhanced resistance to a virulent strain of the bacterial pathogen Pseudomonas syringae as measured by a significant decrease in both bacterial growth and symptom development as compared to those in wild-type and RNAi plants. The enhanced resistance in the gain-of-function transgenic plants was associated with increased induction of SA-regulated PDF1.2 and JA-regulated PR1 by the bacterial pathogen. Thus, pathogen-induced AtPGR plays a positive role in defense responses to P. syringae.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.6
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• pp.812-817
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• 2012

In "The region of the body in which abdomen pain manifests(腹痛有部分)" of "Dongeuibogam(東醫寶鑑)", the abdomen is divided into the upper abdomen(大腹), umbilicus area(臍腹) and lower abdomen(小腹), which are in turn assigned to 3 Yins of greater yin(太陰), lesser yin(少陰) and reverting yin(厥陰) respectively to explain the causes and treatments of abdomen pain according to their locations. Meanwhile, the present Korean medicine tends to issue herbal formula without considering the cause of regional abdomen pain and the aspect of cold and heat(寒熱), deficiency and excess(虛實) in the symptom. This fragmentary treatment may bring out a serious failure. For the correction of this problem, the literature study on "The region of the body in which abdomen pain manifests(腹痛有部 分)" of "Dongeuibogam(東醫寶鑑)" was carried out to obtain the following conclusions. In "The region of the body in which abdomen pain manifest (腹痛有部分)" of "Dongeuibogam(東醫寶鑑)", it turned out that the use of herbal formula for the abdomen pain was the integrated one of herbal formulas for the abdomen pain in the external contraction such as cold damage yin condition(傷寒陰證) and cold in the middle condition(中寒證) and that the cause of abdomen pain was the explanation of diverse internal causes for the abdomen pain. And it was also found that the assignment of the upper abdomen(大腹), umbilicus area(臍腹) and lower abdomen(小腹) to 3 Yins had the locational and meridian meanings of 3 Yins according to internal causes and external contraction to get the basis of abdomen pain treatment in dividing it into 3 Yins.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.1
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• pp.8-18
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• 2011

To have effective treatment for shoulder arm pain, we searched the cause, symptom, etiology, classification of the pain areas, acupuncture points, and muscles along the meridians, and acquired the following results. Shoulder-pain is mainly divided into the malfunction of viscera and entrails, damage due to the weakness of essence and qi, abnormal status of muscle function, change of joints, disease in the nerve and vessel, and the internal injury due to seven modes of emotions. Pain of shoulder joints are pain in the local area of shoulder joints, referred pain of shoulder, neck, and shoulder-arm, numbnes and swelling of muscle, and muslce weakness. Shoulder-arm pain is classified as four types of pain: shoulder-joint pain, shoulder-back pain, shoulder-chest pain, and shoulder-arm-elbow pain. And shoulder-arm-elbow pain is again divided into the shoulder-blade pain, shoulder-arm pain, shoulder-elbow pain. The related meridians on shoulder pain are the three yin meridians of hand, Kidney Meridian, Conception Meridian, three yang meridians of hand, Bladder Meridian, Governor Meridian Acupuncture points for shoulder pain are in the acupuncture points of the 10 meridians and a-shi points. Thre related meridian muscles on shoulder-pain are the three yin and yang meridians of hand, and their related muscles are the ones that are connected with the front, back, and chest side muscles of shoulder joints, and the ones that are connected with the front and back side muscles of arm.