• 제목/요약/키워드: physiological status

검색결과 474건 처리시간 0.031초

Neuroprotective Effects of Guh-Poong-Chung-Sim-Hwan on Focal Cerebral Ischemia in Rats

  • Lim, Ha-Sup;Kim, Jeung-Beum
    • 동의생리병리학회지
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    • 제19권1호
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    • pp.246-253
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    • 2005
  • This study was designed to investigate the neuroprotective effects of Guh-Poong-Chung-Sim-Hwan(GCH) on ischemia induced by middle cerebral artery occlusion(MCAO) in Sprague-Dawley rats. The effects of GCH administration on the size of the brain infarct and the functional status of the rats after ischemia were examined, as well as the expression of COX-2 in acute phase. The recovery of motor functions for 7 days and the brain infarct were examined to find out the delayed effects of daily GCH-administration as well. In conclusion, we found that GCH reduced both functional deficits and brain damage in the MCAO rat model of stroke. In addition, high doses of GCH reduced COX-2 expression in the penumbra. It is well known that herbal medication including GCH is very safe for humans. Accordingly, our results support the clinical use of this GKM for the treatment of stroke and offer the possibility that a potent neuroprotective agent could be developed from Korean herbal medicines.

변형 Fontan 수술의 임상적 고찰8 (Clinical Experiences of Modified Fontan Operation in 8 cases)

  • 문경훈
    • Journal of Chest Surgery
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    • 제20권3호
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    • pp.536-543
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    • 1987
  • The Fontan procedure was physiological correction which was initially applied to tricuspid atresia. We had used the modified Fontan operation in 8 cases at National Medical Center, Seoul, from Aug. 1984 to Oct. 1986. Age range was 20 months to 15 years [mean: 9 years] and male: female ratio was 5:3. 5 patients had tricuspid atresia [lb: 2 cases, Ic: 1 case, lib: 1 case, & llc: 1 case], 2 Patients had univentricular heart of left ventricular type, and one patient had transposition of great arteries with complete endocardial cushion defect. The operative principle was direct anastomosis between right atrium and pulmonary artery, whether main pulmonary artery or right pulmonary artery without any conduits. Postoperatively all patients needed high central venous pressure for adequate hemodynamic status in both survival [20-24 CmH2O] and mortality groups [20-24 CmH2O]. The fatal complications were as follows: empyema with bronchopleural fistula [1 case], bleeding tendency & brain damage [1 case], low cardiac output syndrome & acute renal failure [2 cases], and right to left shunt of unknown origin [1 case]. There were 5 hospital deaths; 3 of 5 tricuspid atresia patients, 1 of 2 univentricular heart patients, and 1 of 1 transposition of great arteries with complete endocar4ial cushion defect patient. The overall mortality was 62.5%. 3 survivors were nearly compatible with Choussat & Fontan criteria. Thus appropriate patient selection and experienced surgical technique were required for good results.

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Effects of Intra-peritoneal Injection of Inorganic Mercury on Blood Parameters and Hepatic Oxidative Stress Enzyme Activities in Common Carp (Cyprinus carpio L.)

  • Jee, Jung-Hoon;Kang, Ju-Chan
    • 환경생물
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    • 제22권4호
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    • pp.559-564
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    • 2004
  • The effects of intra-peritoneal injection of inorganic mercury on haemato-logical parameters and hepatic oxidative stress enzyme activities were studied in common carp, Cyprinus carpio. The fish were injected thrice intra-peritoneally with mercuric chloride TEX>$(5,\;10mg\;Hg\;kg\;b.W.^{-1})$. After exposure of three different mercury concentrations a physiological stress response was exerted on C. carpio by causing changes in the blood status such as erythropenia in blood and oxidative stress in liver. Red blood cell counts, hemoglobin concentration and hematocrit level were reduced in most cases by inorganic mercury. Remarkable low level of serum chloride, calcium and osmolality were also observed in the mercury- exposed fish. However, serum magnesium and phosphate were not altered by exposure to mercury. An increased activity of hepatic glutathione peroxidase was observed in the lowest treatment group of carp $(1mg\;Hg\;mg\;b.w.^{-1})$, hence, hepatic catalase and glutathione peroxidase of carp exposed to higher concentration of mercury $(5,\;10mg\;Hg\;kg\;b.W.^{-1})$ showed significant reduction in such activities.

급격한 광도 변화가 담배 잎에서 반사되는 Normalized Difference Vegetation Index에 미치는 영향 (Effect of a Sudden Increase in Light Intensity on Normalized Difference Vegetation Index (NDVI) Reflected from Leaves of Tobacco)

  • 서계홍
    • 한국환경과학회지
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    • 제26권4호
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    • pp.543-547
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    • 2017
  • Normalized Difference Vegetation Index (NDVI) has played an important role in assessing green plant biomass through remote sensing on global scale since the early 1970s. The concept of NDVI is based on the fact that green plants show higher reflection in near-infrared region than in visible region of the electromagnetic spectrum. However, it is well known that the relocation of chloroplasts in plant leaf cells may dramatically change the optical properties of plant leaves. In this study I traced the changes in the reflectance and transmittance properties of Tobacco leaves at the wavelengths of 660 and 800 nm after a sudden increase in light intensity. The results showed that NDVI of leaves gradually decreased from 72.7% to 69.9% when exposed to a sudden increase in light intensity from 30 to $1,200{\mu}mol/m^2{\cdot}s$. This means that the error resulting from the physiological status of the plant should be accounted for a more precise understanding of ground truth corresponding to the data from the remotely acquired images.

치과치료 공포감 및 치과의사 불신감의 관련요인 분석 (Analysis of related factors for dental treatment of fear and distrust of dentists)

  • 최성숙
    • 한국치위생학회지
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    • 제12권6호
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    • pp.1148-1157
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    • 2012
  • Objectives : The purpose of this study is to analyze factors impacting dental treatment of fear and distrust of dentists. The subjects of this study consists of 720 middle & high school students in Daegu area. Methods : The data were collected from June 1, 2009 to September 30, 2009 by self-administrative questionnaires. The data received was analyzed using the descriptive statistic, t-test, ANOVA, and multiple linear regression analysis with level of significance as p<0.05 stimulus response factors in oral health education, often highly-experienced, and distrust of the dentists of factors the lower stimulus response factors are highly. Results : A female dental treatment of fear and distrust of dentists showed higher than male. Showed higher dental treatment of fear and the higher distrust of dentist. Showde the treatment-avoidance factors the higher patient of negligence factors and distrust of dentists factors are highly statistically significant. Showed the stimulus response factors in oral health education, often highly-experienced, and distrust of the dentists of factors the lower stimulus response factors are highly. Showed the similar results physiological arousal factors and the stimulus response factors. Conclusions : The results suggest that oral health status of improve adolescent before treatment of patients identify biological characteristics and personality can decrease dental treatment of fear and distrust of dentist.

ENERGY UTILIZATION MODELS OF CATTLE GRAZING IN OIL PALM PLANTATIONS II. VALIDATION OF MODELS

  • Dahlan, I.;Mahyuddin, M.D.;Yamada, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • 제8권1호
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    • pp.67-73
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    • 1995
  • This study showed that models of energy utilization(EU) developed for grazing cattle in oil palm plantations is valid as the simulated results shows an agreement with actual data of calves and cows body weight changes collected from Brahman x Kedah-Kelantan herd on Pengeli Timor Plantation. Simulation runs on EU models demonstrated that the growth pattern of male and female calves and the weight changes of cows are similar and showed slight variation from the actual data but with no significant difference (p > 0.05). Parameter values such as metabolizability (q), dry matter digestibility(DMD) of herbage and voluntary intake of grazing cattle (VIG) and faecal output/body weight ratio (F) of the animals which were collected from the field are essential in bearing the pattern of body weight changes of the calves and cows in relation to increase in time, physiological status and quality of herbage grazed by these animals in the production system. The EU models is suitable for determining the metabolizable energy requirements and to predict the production of grazing cattle according to quality of the feed on offer.

Changes in Hematological, Biochemical and Non-specific Immune Parameters of Olive Flounder, Paralichthys olivaceus, Following Starvation

  • Kim, Jong-Hyun;Jeong, Min Hwan;Jun, Je-Cheon;Kim, Tae-Ik
    • Asian-Australasian Journal of Animal Sciences
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    • 제27권9호
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    • pp.1360-1367
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    • 2014
  • Triplicate groups of fed and starved olive flounder, Paralichthys olivaceus (body weight: $119.8{\pm}17.46$ g), were examined over 42 days for physiological changes using hematological, biochemical, and non-specific immune parameters. No significant differences in concentrations of blood hemoglobin and hematocrit and plasma levels of total cholesterol, aspartate aminotransferase, alanine aminotransferase, glucose, and cortisol were detected between fed and starved groups at any sampling time throughout the experiment. In contrast, plasma total protein concentrations were significantly lower in starved fish than in fed fish from day 7 onwards. Moreover, plasma lysozyme concentrations were significantly higher in starved flounder from day 21 onwards. This result confirms that the response of olive flounder to short-term (less than about 1.5 months) starvation consists of a readjustment of metabolism rather than the activation of an alarm-stress response. The present results indicate that starvation does not significantly compromise the health status of fish despite food limitation.

경식도 심초음파 검사를 이용한 판막대치술 환자의 평가 (Postoperative Transesophageal Echocardiographic Evaluation in Patients with Cardiac Valve Replacement)

  • 조건현
    • Journal of Chest Surgery
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    • 제24권3호
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    • pp.265-270
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    • 1991
  • Since advent of the prosthetic cardiac valve replacement, much efforts for accurate assessing value function in-vivo have been attempted. To evaluate the postoperative functional and morphological status of the replaced cardiac valve prosthesis, 33 patients with valve replacement were studied by transthoracic and transesophageal 2-dimensional echocardiac imaging as well as by color Doppler flow velocity imaging. Twenty four patients had mitral valve replacement. 6 patients had aortic valve replacement and 3 patients had both mitral and aortic valve replacement. There were 34 mechanical and 2 biological prosthesis. Comparing to transthoracic echocardiography, transesophageal approach showed transvalvular regurgitant jet flow amid the prosthetic mitral valve ring during. systole and much clear visualization of cardiac chamber behind prosthesis which could give shadowing effect to ultrasound beam. According to the quantitative grading by the length and area of mitral regurgitant flow, 24 out of 27 mitral valves revealed mild degree regurgitation considered as physiological after prosthetic bileaflet valve replacement and the other 3 valves including 2 biological prosthesis had moderate degree regurgitation which was regarded as pathologic one. 2 cases of left atrial thromboses and 1 case of paravalvular leakage which were not visible by transthoracic approach were identified by transesophageal echocardiography in patients with mitral valve replacement and patients with aortic valve replacement respectively. We conclude that in patients with prosthetic mitral valve replacement, transesophageal 2-dimensional imaging with color Doppler can suggest reliable information beyond that available from the transthoracic access even though it gives patient some discomfort to proceed.

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Case Series of Zone III Resuscitative Endovascular Balloon Occlusion of the Aorta in Traumatic Shock Patients

  • Yu, Byungchul;Lee, Gil Jae;Choi, Kang Kook;Lee, Min A;Gwak, Jihun;Park, Youngeun;Lee, Jung Nam
    • Journal of Trauma and Injury
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    • 제33권3호
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    • pp.162-169
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    • 2020
  • Purpose: There is increasing evidence in the literature regarding resuscitative endovascular balloon occlusion of the aorta (REBOA) globally, but few cases have been reported in Korea. We aimed to describe our experience of successful Zone III REBOA and to discuss its algorithm, techniques, and related complications. Methods: We reviewed consecutive cases who survived from hypovolemic shock after Zone III REBOA placement for 4 years. We reviewed patients' baseline characteristics, physiological status, procedural data, and outcomes. Results: REBOA was performed in 44 patients during the study period, including 10 patients (22.7%) who underwent Zone III REBOA, of whom seven (70%) survived. Only one patient was injured by a penetrating mechanism and survived after cardiopulmonary resuscitation. All patients underwent interventions to stop bleeding immediately after REBOA placement. Conclusions: This case series suggests that Zone III REBOA is a safe and feasible procedure that could be applied to traumatic shock patients with normal FAST findings who receive a chest X-ray examination at the initial resuscitation.

Instrumentation and Software for Analysis of Arabidopsis Circadian Leaf Movement

  • Kim, Jeong-Sik;Nam, Hong-Gil
    • Interdisciplinary Bio Central
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    • 제1권1호
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    • pp.5.1-5.4
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    • 2009
  • This article is an addendum to the authors’ previous article (Kim, J. et al. (2008) Plant Cell 20, 307-319). The instrumentation and software described in this article were used to analyze the circadian leaf movement in the previous article. Here, we provide detailed and practical information on the instrumentation and the software. The source code of the LMA program is freely available from the authors. The circadian clock regulates a wide range of cyclic physiological responses with a 24 hour period in most organisms. Rhythmic leaf movement in plants is a typical robust manifestation of rhythms controlled by the circadian clock and has been used to monitor endogenous circadian clock activity. Here, we introduce a relatively easy, inexpensive, and simple approach for measuring leaf movement circadian rhythms using a USB-based web camera, public domain software and a Leaf Movement Assay (LMA) program. The LMA program is a semi-automated tool that enables the user to measure leaf lengths of individual Arabidopsis seedlings from a set of time-series images and generates a wave-form output for leaf rhythm. This is a useful and convenient tool for monitoring the status of a plant's circadian clock without an expensive commercial instrumentation and software.