• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.4
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• pp.842-848
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• 2007

We spend a quarter of every night on the dream, it means for us to spend about six years having a dream. But, any portion of the dream are remained the mystery in these days and it goes without saying that these mystery have not been solved from old times. So. the people have not known about the essences of dream for a long time although they have experienced in dreaming in the early days of human history. But, It is necessary to consider the dream to modality of disease diagnosis because many evidences that the dream represents the physiologic and pathologic changes in the human have been proved in recent days. So, we are going to inquire into the things being scattered over many texts of the Oriental Medicine, including the Internal Classics(內經). about the dream and to look the diagnostic significances of the dream with some examples of the modern psychiatric accomplishments.

• The Korean Journal of Soil Zoology
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• v.5 no.1
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• pp.39-46
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• 2000

The distribution and some properties of alkaline phosphatase (ALP) were investigated in the midgut of the earthworm, Eisenia andrei. The ALP activity appeared to be highly polarized toward the luminal side of epithelium, with minor ALP activity in chloragogue tissue. The epithelial and chloragogeneous tissues contained approximately 85 and 15% of total intestinal ALP activity, respectively. The optimal temperature was approximately 37$^{circ}C$ and isoelectricpoint was estimated to be 4. The treatment of neuraminidase and PtdIns-PLC failed to change the migration rate of ALPs. Also, these ALPs appeared to have a wide range of substrate specificity. The relationship between the properties and physiological significances of the midgut ALPs in Eisenia andrei was discussed.

• Journal of the Korean Society of Food Science and Nutrition
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• v.39 no.8
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• pp.1194-1200
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• 2010

This study was carried out to investigate the compositional changes of ginsenosides and phenolic acids of ginseng leaf by fermentation in order to promote the utilization of ginseng leaf. The chief ginsenosides in non-fermented ginseng leaf (NFGL) were ginsenoside-Rg1 (26.0 mg/g), -Re (47.3 mg/g) and -Rd (23.9 mg/g). By fermentation, ginsenoside-Rg1, -Rb1, -Rb2, -Rb3, -Rc and -Re were decreased tremendously and new ginsenoside-Rh2, -Rh1, -Rg2 and -Rg3 appeared. Especially, ginsenoside-Rg3 (3.7 mg/g) on FGL was increased 15-fold compared to that of NFGL (0.2 mg/g). Total phenolic compound content of NFGL and FGL measured by colorimetric analysis was 350.4 and 312.5 mg%, respectively. There were 8 free and 6 ester forms of phenolic acids in NFGL. Among them, content of ferulic acid was the highest, comprised of 12.6 and 50.7 mg%, respectively. In FGL, total content of protocatechuic acid, p-hydroxybenzoic acid, and vanillic acid were increased by 28, 5 and 7.8 fold and ferulic acid was decreased greatly. Tyrosinase inhibitory activity of FGL was stronger than NFGL, while electron donating abilities of FGL were similar to NFGL.

• Journal of the Korean Society of Clothing and Textiles
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• v.18 no.2
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• pp.273-282
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• 1994

The physiological significances of the upper and lower body on thermoregulation and sensation were studied in this paper. Experiments were carried out on 4 females in a climatic chamber conditioned at 1) $25^{\circ}C\rightarrow35^{\circ}C\rightarrow25^{\circ}C$, 2) $25^{\circ}C\rightarrow15^{\circ}C\rightarrow25^{\circ}C$, both with 50% R.H., covering the upper body (U) or lower body (L) with garments. 1. When the upper or lower body is covered or exposured respectively, the mean skin tempterature of upper body is higher than that of lower body. And upper body is more easily influenced by the environmental temperature than lower body. It means the skin temperatures of the upper body change faster than those of the lower body following the environmental changes. 2. In U and L, the skin temperatures of the upper limbs (thighs, upper arms) are lower than those of the peripherals (hands, feet). 3. Warm sensations and skin temperatures of the upper body showed high correlation and it was the case with cold sensations and skin temperatures of the lower body. 4. In high temperature condition $(25^{\circ}C\rightarrow35^{\circ}C\rightarrow25^{\circ}C)$, mean skill temperature and rectal temperature in L were lower than in U. This lower rectal temperature in L is probably due to the insulation of the lower body with garments that promotes the heat radiation only in the high temperature environment.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.1
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• pp.262-267
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• 2006

We verified the reproducibility of constitution by IGM and the agreement rate between sasang constitution by QSCCII and constitution by IGM. We analyzed the results of 64 subject who were judged as identical sasang constitution by repeated QSCC II. First, we compared the two results of constitutions by IGM hat peformed by one O.M.D(Oriental Medicine Doctor) at an interval of one year. Second, we examined hypothesis established by one O.M.D, that is about relation of constitutions by IGM and QSCCII, such as I type-Taeeumin, II type-Soyangin and III type-Soeumin in constitutions. There were no statistical significances in reproducibility of constitution by IGM. Although there was a tendency of relevance of sasang constitution by QSCC II with constitution by IGM, there was no statistical significance. Hypothesis that is established by clinical experiences must be verified by an effective statistical method. And there is a necessity to complement the method including mechanical measurements about constitution classification which are performed by a diagnosis relying on individual intuition.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.56 no.4
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• pp.349-360
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• 2011

The objectives of present study were to characterize the peptides which were isolated from Korean fermented soybean paste, chungkukjang, and to determine their antioxidant activities. Four fractions were collected from the methanol extract of chungkukjang by using a recycling preparative HPLC. Among fractions, Fr-2 was identified to be highly potent free radical scavenging activity in the assay of 1,1-diphenyl-2-picryl-hydrazyl (DPPH) and nitroblue tetrazolium(NBT)-reduction inhibition. Base on antioxidant effects, fraction Fr-2 was employed for the refraction with a prep-column and separated into five fractions of which two fractions were identified to have higher antioxidant activity. To confirm the amino acid constituents of antioxidant fractions Fr-2-2 and Fr-2-3 were analyzed, and eight kinds of amino acids such as aspartic acid, threonine, serine, glutamic acid, glycine, lysine, histidine, and arginine were identified as the constituent amino acids. Antioxidant activities of the separated peptides were further assessed cell viability with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl terazolium bromide (MTT), and fluorescence-activated cell sorting (FACS) analysis of H4IIE cells treated with hydrogen peroxide (H2O2). Chungkukjang peptides have shown their ability to protect H4IIE rat hepatoma cells against H2O2- induced oxidative stress by concentration and time-dependent manner. Therefore, These results indicated that fermented soybean paste chungkukjang will be promoted the antioxidant and radical scavenging activities, and beneficial for health. The antioxidant peptide fractions Fr-2-2 and Fr-2-3 were denominated as P-NICS-1 and P-NICS-2, respectively. However, further studies were required to clarify their amino acid sequences and molecular properties, and physiological significances.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.2
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• pp.488-493
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• 2006

To make a objective diagnosis of Dam Hun(痰暈), we investigated the 63 patients with Dam Hun(痰暈) and 34 normal people as control group. we compared the thermal difference between Chon-jung(CV17 ) and Chung-wan(CV12 中脘), Chon-jung(CV17 ) and Gwan-won(CV4 關元) and we compared the thermal difference of Yang-mun(ST21 梁門), Chun_chu(ST25 天樞), Su-do(ST28 水道), too. All 63 patients had dizziness and GI trouble. They had the symptom - fatigue, nausea vomitting, head heaviness, indigestion, cold limbs, headache, heart burn, constipation, diarrhea, anorexia. And some had edema, numbness, insomnia, palpitation, facial flushing, dysuria, ringing. Considering the average temparature of Chon-jung(CV17 ), Chung-wan(CV12 中脘), Gwan-won(CV4 關元), Yang-mun(ST21 梁門), Chun-chu(ST25 天樞), Su-do(ST28 水道) between the patients group and the control group, the patients group were lower than the control group except for Chon-jung(CV17 ), Gwan-won(CV4 關元), but the statistical significance was not. Considering the thermal difference of Chon-jung(CV17 ) and Chung-wan(CV12 中脘), Gwan-won(CV4 關元), Yang-mun(ST21 梁門), Chun-chu(ST25 天樞), Su-do(ST28 氷道) between the patients group and the control group, the temparature deviation of Chon-jung(CV17 ) and Chung-wan(CV12 中脘), Chon-jung(CV17 ) and Yang-mun(ST21 梁門) was significant. We suggest that coldness of upper abdomen is significant in diagnosis of Dam Hun(痰暈).

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.4
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• pp.557-565
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• 2012

The purpose of this study was to examine the effect of acupuncture on trunk flexors compared with trunk extensors in patients with chronic low back pain. The experimental group was treated with acupuncture on trunk flexors. The control group was treated with acupuncture on trunk extensors. Acupuncture treatment was performed 12 sessions over the course of 6 weeks. Volunteers who satisfied the requirements were enrolled in the study. Chronic low back pain was evaluated based on the VAS for bothersomeness, VAS for pain intensity at every treatment and 8, 12 and 24 weeks after starting the treatments, and ODI, SF-36 and BDI before and after treatments and 8, 12 and 24 weeks after starting the treatments. The VAS score for bothersomeness significantly decreased after treatment for up to 24 weeks after starting the treatments in both group (p<0.05). The VAS score for bothersomeness in the experimental group decreased more rapidly than that of the control group with statistical significance (p<0.05). The VAS score for pain intensity, ODI, SF-36 and BDI significantly improved after treatment for up to 24 weeks after starting the treatments in both group (p<0.05). The VAS score for pain intensity, ODI, SF-36 and BDI in the experimental group showed more rapid improvement than those of the control group. But, there were no statistical significances. Treating trunk flexors using acupuncture was more effective in decreasing the degree of bothersomeness caused by chronic low back pain than treating trunk extensors with acupuncture. There is a need to perform further studies.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.6
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• pp.934-939
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• 2012

To investigate and characterize basic patterns of prehypertension. Participants were divided into three groups; ideal blood pressure(n=40), prehypertension(n=62), and stage 1 hypertension groups(n=68) according to the JNC 7 standards. They answered questionnaire asking various symptoms and received clinical examination. Data were collected and analyzed in the focus of three Zheng patterns, cold-heat, deficiency-excess and four major hypertension types. Analysis of variance was used to find differences among groups. In addition, relationship between the cold-heat trends and risk factors of hypertension were analyzed using Pearson's correlation analysis. Three risk factors; age, body mass index (BMI), and fasting blood sugar (FBS) showed intergroup differences. Statistical significances were revealed in the cold-heat pattern and two hypertension subtypes. The cold scores decreased from $4.8{\pm}1.84$ to $3.9{\pm}1.88$ and $3.7{\pm}1.27$ (p=0.022), while the heat increased from $1.9{\pm}1.32$ to $2.8{\pm}1.72$ and $2.8{\pm}1.48$ (p=0.009). Additionally two hypertension subtypes, the excessive liver fire, and the yin-yang deficiency showed significant differences. Cold had negative correlations with blood pressure (both systolic and diastolic), BMI, triglyceride, and FBS. Heat had positive correlations with systolic blood pressure, BMI, triglyceride, and FBS. Prehypertension could be characterized by using the cold-heat patterns. The cold-heat are correlated with Blood pressure, BMI, blood lipids and sugar.

• Journal of the Korean Society of Clothing and Textiles
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• v.17 no.1
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• pp.19-35
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• 1993

This study was designed to devise work wear for plastic house worker. It was carried out (1) research on the clothing actual condition through interviewings with plastic house worker and observations, (2) thermal manikin test to measure thermal resistance of experimental clothes and (3) clothing comparing test in the laboratory and in the plastic house. In the laboratory experiment, it was choosen general type (A) and new devised types (B, C) made of microporous fabric for experimental clothes. Experimental clothes were made of 6 combinations including 3 type work wears (A, B, C) and 2 type underwears (1, 2). In the plastic house experiment, it was choosen general types of A (without rest place) and B (with rest place), and devised type C (with rest place), which was appeared good effect in the laboratory experiment. The results were as followings. 1. Work environment of the plastic house in summer and winter was very different from the outer environment. Work motion in the plastic house was burden to the plastic house workers. 2. Plastic house workers had on the general type's work wear. 3. As a result of thermal manikin test, thermal resistance was appeared B1>B2>C2>C1>A1>A2 in orders. 4. In the laboratory experiment, experimental clothes A was appeared smaller burden than B, C. Effect of mesh underwear was not appeared in this study condition. In subjective sensation, experimental clothes C was lower vote than A. Therefore experimental clothes C was superior to A in subjective wearing sensation. 5. In the plastic house experiment, the experimental conditions with rest place were appeared smaller burden than without rest place. General type B was appeared more positive physiological reactions than devised type C but significances between two types was not appeared.