• Child Health Nursing Research
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• 제19권3호
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• pp.198-206
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• 2013

목적 본 연구는 신생아중환자실에 입원해 있는 저출생체중아를 대상으로 '어머니의 노래 들려주기 중재'의 효과를 규명하기 위해 수행되었다. 방법 서울 시내에 소재하는 일개 대학병원의 신생아중환자실에 입원한 대상자를 임의표출하여 비동등성 대조군 전후설계로 총 48명의 영아중 실험군 24명, 대조군 24명을 대상으로 하여 본 연구를 수행하였다. 결과 어머니의 노래 들려주기 중재를 제공받은 저출생체중아는 활력징후의 생리적 반응인 심박동수, 호흡수와 산소포화도에서 실험군과 대조군 사이에 통계적으로 유의한 차이가 없었다. 행동상태 점수는 두 집단 간 통계적으로 유의한 차이가 검증되었다. 즉, 노래 들려주기 중재를 제공받은 저출생체중아는 행동상태가 안정되는 결과를 보였다. 결론 본 연구를 통해 신생아중환자실에서 오랜 기간 치료를 받아야 하는 저출생체중아를 위한 긍정적인 청각자극으로서 어머니의 노래 들려주기 중재를 활용할 수 있는 객관적인 근거자료를 마련하였다는 데 의의가 있다. 또한 이러한 중재를 통해 재원기간 동안 저출생체중아의 돌봄에 어머니의 참여를 독려할 수 있을 뿐만 아니라 영아와 부모 사이의 이른 상호작용을 증진시키는 기회를 제공할 수 있다는 점에서 아동간호실무의 발전에 기여할 수 있을 것이다.

• 한국식품영양과학회지
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• 제15권4호
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• pp.72-80
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• 1986

The purpose of this study was to investigate the dietary-intake and that of health by mean of questionarie and interview for male and female old persons living in Seoul area. The contents of study included general aspects, physical status and health, nutrient intake, and food intake frequency. The results from the above survey are summarized as follows ; 1. The age group in the range of 60 to 79 years old was 71%, and the average number of family was 4.9. The educational level was 56% of elderly persons were elementary or middle school graduates . 42.8% of elderly persons had an average monthly income of \490,000 to 300,000. 2. The aged average height, weight, and physical index were 164.9cm, 55.8kg and 20.4 in male, 152.7cm, 46.0kg and 20.3 in female which were lower than the Korean average standard. (male; 167.0cm, 61.0kg, female; 156.0cm, 55.0kg) In the degree of health self-consciousness, percentage distribution of poor and very poor was 29% in male, 59% in female. Among the condition of disease, neuralgia was 23.8%, hypertension was 17.2%, diabetes was 5.4%. 3. Average daily calorie intake was $63.9{\sim}70.4%$ for male and $76.4{\sim}83.9%$ for female which were lower than the Recommended Dietary Allowances for Koreans. Protein intake was $42.9{\sim}57.3g$ (which was $72.8{\sim}82.6%$ RDA) for elderly person, the proportion of animal protein to total protein intake were $24.3{\sim}28.2%$($12.9{\sim}16.2g$). Iron, Vitamin $B_1$, $B_2$ Niacin intake exceeded the RDA, but the intake of Calcium, Vitamin C were far less than that of RDA. 4. In the correlations between nutritional intakes and environmental factors and health, economic living situations and educational level as the factors which might influence the condition of nutritional intake was significant(P<0.01). 5. Food intake frequency of meats, fishes, eggs, for average of $1{\sim}2$ days per week were $44.8{\sim}50.5%$, that of milk and milk products for scarecely week were 42.9.% Correlation of food intake frequency was divided three levels-good, fair, poor. Food intake frequency as the factors which might influence the condition of nutritional intake was significant(P<0.01). The results of the survey reveal that many of elderly show evidence of general nutrient intake deficiency, it requires first of all importance of nutrition to improve nutritional level through to promotion of elderly health.

• 한국대기환경학회지
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• 제30권2호
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• pp.188-200
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• 2014

The IPCC 5th Assessment Report (Climate Change 2013: The Physical Science Basis) was accepted at the 36th Session of the IPCC on 26 September 2013 in Stockholm, Sweden. It consists of the full scientific and technical assessment undertaken by Working Group I. This comprehensive assessment of the physical aspects of climate change puts a focus on those elements that are relevant to understand past, document current, and project future of climate change. The assessment builds on the IPCC Fourth Assessment Report and the recent Special Report on Managing the Risk of Extreme Events and Disasters to Advance Climate Change Adaptation. The assessment covers the current knowledge of various processes within, and interactions among, climate system components, which determine the sensitivity and response of the system to changes in forcing, and they quantify the link between the changes in atmospheric constituents, and hence radiative forcing, and the consequent detection and attribution of climate change. Projections of changes in all climate system components are based on model simulations forced by a new set of scenarios. The report also provides a comprehensive assessment of past and future sea level change in a dedicated chapter. The primary purpose of this Technical Summary is to provide the link between the complete assessment of the multiple lines of independent evidence presented in the main report and the highly condensed summary prepared as Policy makers Summary. The Technical Summary thus serves as a starting point for those readers who seek the full information on more specific topics covered by this assessment. Warming of the climate system is unequivocal, and since the 1950s, many of the observed changes are unprecedented over decades to millennia. The atmosphere and ocean have warmed, the amounts of snow and ice have diminished, sea level has risen, and the concentrations of greenhouse gases have increased. Total radiative forcing is positive, and has led to an uptake of energy by the climate system. The largest contribution to total radiative forcing is caused by the increase in the atmospheric concentration of $CO_2$ since 1750. Human influence on the climate system is clear. This is evident from the increasing greenhouse gas concentrations in the atmosphere, positive radiative forcing, observed warming, and understanding of the climate system. Continued emissions of greenhouse gases will cause further warming and changes in all components of the climate system. Limiting climate change will require substantial and sustained reductions of greenhouse gas emissions. The in-depth review for past, present and future of climate change is carried out on the basis of the IPCC 5th Assessment Report.

• Journal of Ginseng Research
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• 제32권3호
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• pp.210-219
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• 2008

본 연구는 8주간의 홍삼 투여가 중추피로 및 말초피로에 미치는 영향과 홍삼 투여와 지구성 트레이닝을 병행 했을 경우, 홍삼이 유 무산소성 운동수행능력에 미치는 영향을 관찰하였다. 그 결과 홍삼 섭취와 지구성 트레이닝을 병행하는 것이 홍삼 섭취와 지구성 트레이닝을 단독으로 적용하는 것 보다 유산소성 운동수행능력과 말초피로에 높은 효과를 기대할 수 있으며, 홍삼의 섭취가 중추피로에도 긍정적인 영향을 미칠 것으로 기대된다. 하지만, 무산소성 운동수행능력에는 큰 영향을 주지 못하는 것으로 생각된다. 이에, 본 연구를 통해 검증된 홍삼의 피로회복 및 운동수행능력 향상 효과는 추후 일반인뿐만 아니라 운동선수의 운동능력향상 보조물(Ergogenic aid)로써 도움을 줄 것으로 기대된다.

• Archives of Pharmacal Research
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• 제26권10호
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• pp.846-854
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• 2003

The oligomerization of G-proteincoupled receptors (GPCRs) has been shown to occur by various mechanisms, such as via disulfide covalent linkages, non covalent (ionic, hydrophobic) interactions of the N-terminal, and/or transmembrane and/or intracellular domains. Interactions between GPCRs could involve an association between identical proteins (homomers) or non-identical proteins (heteromers), or between two monomers (to form dimers) or multiple monomers (to form oligomers). It is believed that muscarinic receptors may also be arranged into dimeric or oigomeric complexes, but no systematic experimental evidence exists concerning the direct physical interaction between receptor proteins as its mechanism. We undertook this study to determine whether muscarinic receptors form homomers or a heteromers by direct protein-protein interaction within the same or within different subtypes using a yeast two-hybrid system. Intracellular loops (i1, i2 and i3) and the C-terminal cytoplasmic tails (C) of human muscarinic (Hm) receptor subtypes, Hm1, Hm2 and Hm3, were cloned into the vectors (pB42AD and pLexA) of a two-hybrid system and examined for heteromeric or homodimeric interactions between the cytoplasmic domains. No physical interaction was observed between the intracellular domains of any of the Hm/Hm receptor sets tested. The results of our study suggest that the Hm1, Hm2 and Hm3 receptors do not form dimers or oligomers by interacting directly through either the hydrophilic intracellular domains or the C-terminal tail domains. To further investigate extracellular domain interactions, the N-terminus (N) and extracellular loops (o1 and o2) were also cloned into the two-hybrid vectors. Interactions of Hm2N with Hm2N, Hm2o1, Hm2o2, Hm3N, Hm3o1 or Hm3o2 were examined. The N-terminal domain of Hm2 was found to have no direct interaction with any extracellular domain. From our results, we excluded the possibility of a direct interaction between the muscarinic receptor subtypes (Hm1, Hm2 and Hm3) as a mechanism for homo- or hetero-meric dimerization/oligomerization. On the other hand, it remains a possibility that interaction may occur indirectly or require proper conformation or subunit formation or hydrophobic region involvement.

• 디지털융복합연구
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• 제13권1호
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• pp.383-396
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• 2015

본 연구의 목적은 건강검진 전문센터를 이용하는 민간검진자의 재검진 요인을 파악하는 것이다. 이를 위해 전국 7개 지역에 건강검진센터를 두고 있는 검진전문기관의 2008년도 70,250명을 대상으로 2012년까지 검진기관을 재방문한 요인을 분석하였다. 재검진 요인 분석을 위해 사용된 변수는 인구사회학적 특성, 유병 및 과거력, 신체계측, 생화학적 검사, 건강실천행태 등으로 교차분석 및 음이항 회귀분석을 실시하였다. 연구결과 19.2%가 2008년부터 2012년까지 매년 건강검진을 받았으며, 남성(exp(${\beta}$)=1.08), 30-40대(exp(${\beta}$)=1.09~1.18), 대구(exp(${\beta}$)=1.78), 광주(exp(${\beta}$)=1.57), 전남(exp(${\beta}$)=1.47), 경남(exp(${\beta}$)=1.52) 지역의 재수검 확률이 높았고, 과체중(exp(${\beta}$)=1.04) 및 고혈압 전단계인 사람(exp(${\beta}$)=1.06), 적정 음주(exp(${\beta}$)=1.17~1.21), 비흡연(exp(${\beta}$)=1.02), 낮은 스트레스(exp(${\beta}$)=1.02~1.06) 등 건강위험 요인을 관리하고 적정운동(exp(${\beta}$)=1.05~1.07) 등의 건강실천을 행하는 사람의 재수검 확률이 높았다. 검진전문기관은 이러한 결과를 바탕으로 CRM 수행 전략을 세우는 등 기관운영의 활성방안을 마련할 수 있을 것이다.

• 한국조리학회지
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• 제21권5호
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• pp.38-49
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• 2015

본 연구는 패밀리레스토랑의 유형적 근거가 고객들의 지각된 위험 및 총만족에 미치는 영향을 알아보기 위한 것이었다. 자료 분석을 위하여 CFA와 SEM이 사용되었다. 유형적 근거는 3개의 요인으로, 지각된 위험은 6개의 요인으로 분석되었다. 분석결과, 유형적 근거 1 '물리적 증거'는 금전적 위험(p<0.01), 성과적 위험(p<0.01), 심리적 위험(p<0.001)에 부정적인 영향을 주었다. 유형적 근거 2 '종사원'은 시간적 위험(p<0.001), 성과적 위험(p<0.001), 심리적 위험(p<0.01), 사회적 위험(p<0.001)에 부정적인 영향을 주었다. 한편 유형적 근거 3 '서비스 과정'은 신체적 위험(p<0.01), 시간적 위험(p<0.05), 금전적 위험(p<0.001), 성과적 위험(p<0.01)에 부정적인 영향을 주었다. 그리고 지각된 위험 중에서 시간적 위험(p<0.001), 성과적 위험(p<0.001), 사회적 위험(p<0.001)은 고객의 총만족에 부정적인 영향을 주는 것으로 나타났다. 결국 본 연구의 결과를 통해 유형적 근거는 고객의 위험인지에 유의한 영향을 주었으며 또한 고객은 이에 따라 만족 혹은 불만족을 하는 것으로 나타났다. 따라서 외식기업은 고객의 위험인지를 감소시키는 마케팅 전략으로써 뿐만 아니라 만족을 유도하는 중요한 대안으로써 유형적 근거를 지속적으로 관리할 필요가 있다.

• Preventive Nutrition and Food Science
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• 제8권1호
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• pp.24-28
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• 2003

There is evidence to suggest that cranberry juice supplements improve the health of the urinary tract by inhibiting the binding of fimbriated uropathogenic E. coli to the bladder mucosa. In patients with neurogenic bladders, urinary tract infections (UTI) are particularly common and often poorly managed by antibiotic treatment. A double-blind, randomized, placebo-controlled trial was undertaken on 29 geriatric and spinal cord injured patients with dysfunctional bladders. They received three times daily at mealtimes a 4 oz bottle of cranberry juice (Ocean Spray Cranberries, USA) or a specially prepared synthetic placebo drink. Two episodes of UTI arose in week one of cranberry intake and none thereafter, compared to four episodes of UTI in 4 placebo patients in weeks four, six and 10. Mean bacterial adhesion counts on bladder cells of the patients rose during the first month of treatment in 71 % of the placebo patients compared to only 31 % of cranberry patients (p < 0.001). The difference persisted to some extent for the second and third months. Bacterial adhesion levels correlated with culture findings (higher adhesion and higher viable counts in urine) (p < 0.001), positive leukocyte nitrite tests (136$\pm$131 bacteria per cell versus 52$\pm$86 in negative tests) (p < 0.001), and higher white blood cell counts (> 10) per high power field (126$\pm$125 versus 48$\pm$85 bacteria per cell) (p<0.001). E. coli was the most frequently isolated organism (40% samples) followed by K. pneumoniae (17%) and a number of other uropathogens. Group B Streptococci, and coagulase negative Staphylococcus were recovered from urine in 4 samples but were not associated with any red blood cell presence. The daily intake of cranberry juice, in amounts which are not detrimental to long term compliance, appeared to have a role in reducing the risk of bladder colonization and infection in a highly susceptible patient population.

• 한국응용과학기술학회지
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• 제34권4호
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• pp.899-907
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• 2017

본 연구는 대사증후군을 가진 65세 이상 노인여성을 대상으로 마루운동을 실시하여 노인활동체력, 혈중지질 및 동맥경직도에 미치는 영향을 조사하였다. 대사증후군을 가진 여성노인 41명을 무작위로 운동군(23명), 통제군(18명)으로 배정하였다. 운동군은 총 12주간 주 3회로 실시하였으며, 운동강도는 30%-60%의 HRR로 점진적으로 증가시켰다. 본 연구결과, 운동군이 노인활동체력(하지근력, 상지근력, 유연성, 심폐지구력 및 신체조성(체지방률, 제지방량, 허리둘레)), 혈중지질(총 콜레스테롤, 중성지방, HDL 콜레스테롤 및 LDL 콜레스테롤) 및 동맥경직도에서 실험 전 후 긍정적인 변화를 보였고, 통제군에 비해 유의한 차이를 나타냈다. 결과적으로 대사증후군을 가진 여성노인들은 마루운동 프로그램 참여에 따라 노인활동체력이 향상되고, 혈중지질과 동맥경직도에 긍정적인 변화가 일어났다. 따라서, 마루운동프로그램은 대사증후군 개선에 효과적인 프로그램임을 시사한다.

• 통합자연과학논문집
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• 제4권1호
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• pp.38-43
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• 2011

The recent global warming may be estimated to give lots of impacts to the human society and biosphere of influencing climate change included by the natural climate variations through the human activity which can directly and/or indirectly play a major role of total atmospheric composition overall. Therefore it currently appears evidences such as hot wave, typhoon, and biosphere disturbance, etc. over the several regions to be influenced by global warming due to increasing the concentration of greenhouse gases in the atmosphere through inducing forest destruction, fossil fuel combustion, greenhouse gases emission, etc. since industrial revolution era. Through the working group report of IPCC (Intergovernmental Panel on Climate Change) for climate change was analyzed by the individual country's current status and figure out the important issues and problems related to the future trend of climate change science with advanced countries preparedness and research, In this study, the first working group report of IPCC focuses on those aspects of the current understanding of the physical science of climate change that are judged to be most relevant to policymakers. As this report was assessed and analyzed by including the progress of climate change science, the role of climate models and evolution in the treatment of uncertainties. This consists of the changes in atmospheric constituents(both aerosols and gases) that affect the radiative energy balance in the atmosphere and determine the Earth's climate, considering the interaction between biogeochemical cycles that affect atmospheric constituents and climate change, including aerosol/cloud interactions, the extensive range of observations snow available for the atmosphere and surface, for snow, ice, and frozen ground and for the oceans, respectively and changes in sea level, the paleoclimate perspective and assessment of evidence for past climate change and the extension, the ways in which physical processes are simulated in climate models and the evaluation of models against observed climate, the development plans and methods of improving expert and building manpower urgently and R&D fund expansion in detail for climate change science in Korea will be proposed.