• Title/Summary/Keyword: physical evidence

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A Clinical Research Analysis of the Korean Medicine for Peroneal Nerve Palsy (비골신경마비에 대한 국내 한의치료 임상연구 동향 분석)

  • Hong, Su Min;Lee, Eun Jung
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.3
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    • pp.61-74
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    • 2019
  • Objectives This study aimed to review clinical studies about Korean medicine used in peroneal nerve palsy. Methods In 11 online databases (Earticle, Research Information Sharing Service, Oriental Medicine Advanced Searching Integrated System, KMbase, Korean Traditional Knowledge Portal, National Digital Science Library, MEDLINE/Pubmed, Ebscohost, Cochrane CENTRAL, EMBASE, China National Knowledge Infrastructure), we searched clinical studies about Korean medicine. Among the studies that we've searched, we excluded the studies that are not related to Korean medicine, case reports, randomized controlled trials and retrospective studies. As a result, 16 case studies and 1 randomized controlled trial are included. Results Total number of patients was 123. In these studies, acupuncture (100%), herbal medicine (58.8%), pharmacopuncture (58.8%), Korean physical therapy (58.8%), moxibustion (41.1%), cupping (41.1%) etc. were used. In acupuncture, GB34 and ST36 were most frequently used. Most of the herbal medicines used in these studies were different. Range of movement were most frequently used in outcome measure. Conclusions In this study, we reviewed studies about Korean medicine used in peroneal nerve palsy. It was difficult to clearly determine which intervention has improved the symptom. In the future, Further clinical studies will be needed to retain the evidence for the treatment of peroneal nerve palsy. And also more randomized controlled clinical trials to prove the efficacy of Korean medicine will be needed.

On the Global and Local Environmental Dependence of Type Ia Supernova Luminosity from the Analysis of SALT2 and MLCS2k2 Light-Curve Fitters

  • Kim, Young-Lo;Lee, Young-Wook
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.1
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    • pp.40.3-40.3
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    • 2019
  • There is growing evidence for the dependence of Type Ia supernova (SN Ia) luminosities on the environments. The origin of this correlation, however, is under debate. In order to explore the physical origin of the trend in detail, we analyze SN Ia light-curves by combining a sample of 1231 SNe Ia over a wide redshift range (0.01 < z < 1.37) in various SN surveys and employing two independent light-curve fitters of SALT2 and MLCS2k2. Although SALT2 is the most widely used fitter in the SN community, MLCS2k2 has a novelty in the context of an investigation of the luminosity evolution of SNe Ia. For this reason we use both fitters and analyze them separately. We also determine a stellar mass and a star formation rate (SFR) for a sample of ~600 host galaxies. In addition, because recent low-redshift studies suggest that this dependence manifests itself most strongly when using the local SFR at the SN location, we introduce a new method to infer the local environments by restricting the SN Ia sample in globally star-forming host galaxies to a low-mass host galaxy subset (${\leq}10^{10}M_{\odot}$). We find that SNe Ia in low-mass and star-forming host galaxies are fainter than those in high-mass and passive hosts, after light-curve corrections. Especially, for the first time in host studies, we show that SNe Ia in locally star-forming environments are $0.081{\pm}0.018$ mag fainter ($4.5{\sigma}$) than those in locally passive environments from the sample including SNe at the high-redshift range. Considering the significant difference in the mean stellar population age between these environments, the result would suggest that the origin of the environmental dependence is the luminosity evolution of SNe Ia.

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The Analysis of Korean Clinical Studies on the Effect of Pharmacopuncture for Whiplash Injury after Traffic Accidents

  • Yun, Jung Min;Hur, Na Yeon;Kim, Kyeong Han
    • Journal of Pharmacopuncture
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    • v.23 no.4
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    • pp.262-272
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    • 2020
  • Objectives: Whiplash injury is one of the major diseases in recent times because of increasing traffic accidents. This review aims to analyze the overall trend of studies on pharmacopuncture for whiplash injury after traffic accidents. Methods: We searched through 4 Korean electronic databases from 2001 up to October 2020 for relevant clinical studies for whiplash injury after traffic accidents, regardless of the patients' age, gender, or race. We included studies that had an intervention group receiving pharmacopuncture therapy with or without other additional treatments, and also included studies that had a control group receiving sham treatment or active treatment such as physical therapy and herbal medication. For the clinical outcomes, we did not place any restrictions on evaluation scales if they are objective metrics. Results: We included 6 randomized controlled trials (RCTs) and 10 non-randomized controlled trials (nRCTs). 10 nRCTs were divided into 4 categories that were case-control studies, case series, case report, and retrospective observational study. In RCTs, Hwangryun-haedoktang (黃蓮解毒湯) pharmacopuncture was the most frequently used. In nRCTs, Jungsong-ouhyul (中性瘀血) pharmacopuncture, and bee venom pharmacopuncture were the most frequently used. As target points of Hwangryun-haedoktang pharmacopuncture, Ashi-points, Jianjing (GB21), and Fengchi (GB20) were the most frequently used. As target points of Jungsong-ouhyul pharmacopuncture, Ashi-points were the most frequently used. And as target points of Bee venom pharmacopuncture, Fengchi (GB20) was the most frequently used. Conclusion: Hwangryun-haedoktang pharmacopuncture, bee venom pharmacopuncture, and Jungsong-ouhyul pharmacopuncture were mainly used for whiplash injury, and their usual target points were Jianjing (GB21), Fengchi (GB20), and Ashi-points. However, a high level of evidence should be conducted through studies with systematic methodology in the future.

The Effect of Foreign Direct Investment on Public Health: Empirical Evidence from Bangladesh

  • SIDDIQUE, Fahimul Kader;HASAN, K.B.M. Rajibul;CHOWDHURY, Shanjida;RAHMAN, Mahfujur;RAISA, Tahsin Sharmila;ZAYED, Nurul Mohammad
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.4
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    • pp.83-91
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    • 2021
  • Health is an outset of psychological, social, financial, and physical state. Several macroeconomic factors are entangled with health and mortality. Infant mortality and life expectancy are two keyguard on demographic research context on last few decades. On the other hand, foreign inflows play an unprecedent role for raising economic circulation and providing more opportunities to build a better society. The study aims to investigate the relationship between foreign direct investment (FDI), economic growth, and Bangladesh's health. This study employs time-series data from 1980 to 2018. Results show, with Auto-regressive Distribute Lag (ARDL) model, that there is significant cointegration among variables. Foreign investment and economic output relate significantly and positively to health. On the contrary, education is quasi-linked with a different sign-on different model. For model validation, pitfalls of time-series multicollinearity, heteroscedasiticy, and autocorrelation are not present. Also, CUSUM and CUSUMSQ tests are validating the model as stable and fit for future prediction. Medical assessment and education need more attention from the government as well as the private sector. FDI can play a catalyst role for improving the health sector, raising opportunity in educating and creating a better lifestyle. In order to optimize foreign investment, the government should implement necessary reforms and policies.

Surgical Outcomes and Survival Prognostic Factors for Palliative Gastrectomies in Stage IV Resectable Gastric Cancer Outlet Obstruction Patients

  • Choi, Won Yong;Kim, Hyun Il;Park, Seong Ho;Yeom, Jong Hoon;Jeon, Woo Jae;Kim, Min Gyu
    • Journal of Gastric Cancer
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    • v.20 no.4
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    • pp.421-430
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    • 2020
  • Purpose: Currently, there is no clear evidence to support any specific treatment as a principal therapy for stage IV gastric cancer outlet obstruction (GCOO) patients. This study evaluated the outcomes of palliative gastrectomies and survival prognostic factors in patients with stage IV resectable GCOO. Materials and Methods: We retrospectively reviewed the medical records of 48 stage IV GCOO patients who underwent palliative gastrectomies between June 2010 and December 2019. Palliative gastrectomies were performed only in patients with resectable disease. Early surgical outcomes and prognostic factors were analyzed using univariate and multivariate analyses. Results: There were no specific risk factors for postoperative complications, except for being underweight. Severe postoperative complications developed in five patients, and most of the patients underwent interventional procedures and received broad-spectrum antibiotics for intra-abdominal abscesses. The multivariate survival analysis showed that palliative chemotherapy is a positive prognostic factor, while the specific type of hematogenous and lymphatic metastasis is a negative prognostic factor. Conclusions: We recommend that the treatment method for stage IV GCOO should be selected according to each patient's physical condition and tumor characteristics. In addition, we suggest that palliative gastrectomies can be performed in stage IV resectable GCOO patients without unfavorable prognostic factors (types of hematogenous and lymphatic metastases).

Alteration of the gut microbiota in post-weaned calves following recovery from bovine coronavirus-mediated diarrhea

  • Kwon, Min-Sung;Jo, Hee Eun;Lee, Jieun;Choi, Kyoung-Seong;Yu, Dohyeon;Oh, Yeon-su;Park, Jinho;Choi, Hak-Jong
    • Journal of Animal Science and Technology
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    • v.63 no.1
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    • pp.125-136
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    • 2021
  • Bovine coronavirus (BCoV) is associated with severe diarrhea, dehydration, and depression, which result in significant economic damages in the dairy and beef cattle industries worldwide. However, differences in the gut microbiota structure and their correlations with differing physiological parameters between BCoV-infected calves with diarrhea and recovered calves are not well understood. In this study, fecal specimens were collected from 10 post-weaned calves, before and after 2 months of fluid therapy, and the samples were used for microbiota analysis. Following recovery, the alpha-diversity profiles (observed operational taxonomic units [OTUs], and Chao1, Shannon, and Simpson indices) changed significantly when compared with those of calves with diarrhea. Beta-diversity analysis exhibited significant differences in gut microbiota compositions between calves with diarrhea and those in the recovered state. The abundances of eight phyla and thirteen genera in feces changed markedly after restoration of BCoV diarrhea. In addition, our correlation study clearly revealed that increased abundances of the genera Caproiciproducens, Pseudoflavonifractor, and Oscillibacter negatively correlated with serum glucose, and phosphorus levels, but positively correlated with serum chloride in calves with diarrhea, whereas increased abundances of the genera Peptostreptococcaceae;Clostridium (Clostridium cluster XI), Intestinibacter, Cellulosilyticum, Ruminococcus, Romboutsia, Paeniclostridium, Clostridiaceae;Clostridium and Turicibacter in recovered calves showed the opposite pattern. These results suggest that structural changes of the gut microbiota after recovery from BCoV infection correlate with changes in physiological parameters. In conclusion, our data provide evidence of gut microbiota-composition changes and their correlations with the physical profiles of post-weaned calves, before and after fluid therapy for BCoV-related diarrhea.

Use of Aconitum Herbal Medicine for Pain Control in Musculoskeletal Disease (근골격계 질환에서 통증 조절을 위한 부자류 약물의 활용)

  • Park, Hye-Jin;Kim, Hyun-Tae;Lee, Sang-Hyun;Heo, In;Hwang, Man-Suk
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.16 no.2
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    • pp.47-54
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    • 2021
  • Objectives This review was conducted to study use of Aconitum herbal medicine for pain control in musculoskeletal disease. Methods Musculoskeletal disease is a major factor of social cost increase and physical disability. Various drugs, surgery and imaging are being overused regardlessly. Aconitum herbal plants are one of the most toxic Korean traditional herbs. However, they could be utilized effectively on patients with appropriate processing and decocting time. We searched Korean medicine literature to see various features of aconitum herbal plants and tried to find the utilization of the plants in effective way for pain control in musculoskeletal disease. Results Aconitum herbal plants needs to be used carefully because of intoxication which could lead to severe damage to human body. Processing of these toxic plants could minimize the harm and raise the benefits, such as relieving various types of pain and positive inotropic action. Further studies with clearer evidence and discovering aftereffects of processing in more details are needed. Conclusions Aconitum herbal plants could dedicate to controlling pain in musculoskeletal disease with various forms and appropriate processing.

Development of a New Pressure-Sinkage Model for Rover Wheel-Lunar Soil Interaction based on Dimensional Analysis and Bevameter Tests

  • Lim, Yujin;Le, Viet Dinh;Bahati, Pierre Anthyme
    • Journal of Astronomy and Space Sciences
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    • v.38 no.4
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    • pp.237-250
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    • 2021
  • A rover is a planetary surface exploration device designed to move across the ground on a planet or a planetary-like body. Exploration rovers are increasingly becoming a vital part of the search for scientific evidence and discoveries on a planetary satellite of the Sun, such as the Moon or Mars. Reliable behavior and predictable locomotion of a rover is important. Understanding soil behavior and its interaction with rover wheels-the terramechanics-is of great importance in rover exploration performance. Up to now, many researchers have adopted Bekker's semiempirical model to predict rover wheelsoil interaction, which is based on the assumption that soil is deformable when a pressure is applied to it. Despite this basic assumption of the model, the pressure-sinkage relation is not fully understood, and it continues to present challenges for rover designers. This article presents a new pressure-sinkage model based on dimensional analysis (DA) and results of bevameter tests. DA was applied to the test results in order to propose a new pressure-sinkage model by reducing physical quantitative parameters. As part of the work, a new bevameter was designed and built so that it could be successfully used to obtain a proper pressure-sinkage relation of Korean Lunar Soil Simulant (KLS-1). The new pressure-sinkage model was constructed by using three different sizes of flat plate diameters of the bevameter. The newly proposed model was compared successfully with other models for validation purposes.

Association between Urinary 3-Phenoxybenzoic Acid Concentrations and Self-Reported Diabetes in Korean Adults: Korean National Environmental Health Survey (KoNEHS) Cycle 2~3 (2012~2017) (한국 성인에서 요중 3-페녹시벤조익산 농도와 자가보고 당뇨와의 연관성: 제2~3기 국민환경보건기초조사(2012~2017))

  • Choi, Yun-Hee;Moon, Kyong Whan
    • Journal of Environmental Health Sciences
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    • v.48 no.2
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    • pp.96-105
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    • 2022
  • Background: Pyrethroid insecticides account for more than 30% of the global insecticide market and are frequently used in agricultural settings and residential and public pest control among the general population. While several animal studies have suggested that exposure to pyrethroids can alter glucose homeostasis, there is only limited evidence of the association between environmental pyrethroid exposure and diabetes in humans. Objectives: This study aimed to report environmental 3-phenoxybenzoic acid (3-PBA) concentrations in urine and evaluate its association with the risk of diabetes in Korean adults. Methods: We analyzed data from the Korean National Environmental Health Survey (KoNEHS) Cycle 2 (2012~2014) and Cycle 3 (2015~2017). A total of 10,123 participants aged ≥19 years were included. Multiple logistic regressions were used to calculate the odds ratios (ORs) for diabetes according to log-transformed urinary 3-PBA levels. We also evaluated age, sex, education, monthly income, marital status, alcohol drinking, physical activity, urinary cotinine, body mass index, and sampling season as potential effect modifiers of these associations. Results: After adjusting for all the covariates, we found significant dose-response relationships between urinary 3-PBA as quartile and the prevalence of diabetes in pooled data of KoNEHS Cycles 2 and 3. In subgroup analyses, the adverse effects of pyrethroid exposure on diabetes were significantly stronger among those aged 19~39 years (p-interaction<0.001) and those who consumed high levels of cotinine (p-interaction=0.020). Conclusions: Our findings highlight the potential diabetes risk of environmental exposure to pyrethroids and should be confirmed in large prospective studies in different populations in the future.

Economic and non-economic loss and damage to climate change: evidence from a developing country shrimp farms to cyclone Bulbul

  • Islam, Md. Monirul;Nipa, Tanjila Akter;Islam, Md. Sofiqul;Hasan, Mahmudul;Khan, Makidul Islam
    • Fisheries and Aquatic Sciences
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    • v.25 no.4
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    • pp.214-230
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    • 2022
  • Loss and damage have become a vital contemporary issue in climate change studies and actions in developing countries. However, studies are scant on this in the fisheries sector around the world. In Bangladesh, there is no study on the loss and damage in fisheries dependent communities. This study assesses economic and non-economic loss and damage to coastal shrimp farms due to cyclone Bulbul in Gabura Union of Shyamnagar Upazila, Satkhira district, using a mixed method approach. Results show that all shrimp farms' dependent communities are affected by cyclone Bulbul to some extent. About 14%, 57%, and 29% of the farms were totally, heavily and moderately damaged due to farm inundation and dyke damage. The estimated mean loss and damage per shrimp farm was worth USD 4,633. Around 31% and 72% of the farms' fencing nets and traps were lost, which was worth USD 333 per farm. There were also loss and damage to other resources such as houses, solar panels, livestock and agricultural crops where the estimated mean loss and damage per household was worth USD 3,170. This study reported that the rich shrimp farmers encountered proportionately more economic loss and damage than their poor counterparts. However, this does not mean that the poor suffered less. The current study found a range of non-economic loss and damage in different aspects of the shrimp farmers' household members such as unbearable mental pain, deterioration of health, physical injuries, disabilities, etc. and access to services (e.g., inadequate food, lack of safe drinking water, lack of medical facilities, disruption of education systems), social infrastructure (e.g., damage of roads and markets) and disturbance of cultural functions. The findings suggest that urgent short- and long-term actions may be taken to save the aquaculture farms and dependent livelihoods from economic and non-economic loss and damage to cyclones in future.