• Title/Summary/Keyword: physical evidence

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A Meta-Analysis on Factors Related to Quality of Life in Heart Transplant Recipients (심장이식 수혜자의 삶의 질 관련 요인에 대한 메타분석)

  • Jang, Mi Ra;Im, Se Rah;Choi, Mona
    • Journal of Korean Clinical Nursing Research
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    • v.25 no.3
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    • pp.251-264
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    • 2019
  • Purpose: This study was a systematic review and meta-analysis to explore the factors related to quality of life in heart transplant recipients. Methods: To identify studies that suggested the factors related to the quality of life in heart transplant recipients, we searched the articles published from 1974 to November 2018 using Six databases, PubMed, CINAHL, EMBASE, Cochrane, KMBASE and RISS. A total of 22 studies were selected out of 5,234 for the systematic review and meta-analysis on the basis of the PRISMA flow. The quality of study was assessed by assessment tool form the NIH and meta-analysis was performed using the 'R 3.5.2' version to analyze the correlated effect sizes. Results: Factors related to quality of life in heart transplant recipients were categorized into six domains based on the health-related quality of life model introduced by Ferrans: individual, environmental, biological function, symptoms, functional status, and general health perception. In the meta-analysis, 34 factors were used and 17 factors having significant effect sizes were as follows: self-efficacy, demoralization, perceived control, current occupational status, age, marital status, health promotion life style in the individual characteristics; stress in environmental characteristics; physical function status, creatinine level, left ventricular ejection fraction (LVEF) in biological function; anxiety, depression, symptom frequency and distress in symptoms domain; coping, self-care compliance in functional status. Conclusion: The findings indicate that the multi-dimensional factors influencing the quality of life in heart transplant recipients and provide the evidence for developing effective interventions for improving the quality of life of recipients.

A Clinical Trial to Verity the Quality of Life Improvement Efficacy of Dangguijakyak-san and Gyejibongnyeong-hwan Granulation in Postmenopausal Women. (한방 과립제의 폐경 후 삶의 질 개선 효과에 관한 연구 - 당귀작약산 및 계지복령환 과립제의 폐경후 삶의 질 개선에 대한 임상연구)

  • Park, Jea-Min;Yang, Jeong-Min;Kim, Dong-Il
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.3
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    • pp.213-228
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    • 2007
  • Purpose: This master‘s thesis to evaluate the grade of life after medication a Dangguijakyak-san(pasabu) and Gyejibongnyeong-hwan(cheongwal) with in postmenopausal women get lowering quality of life caused by vasomotor symptoms with hot flush. Methods: A subject who signing on the clinical trial written consent by self-will is registered this clinical trial after decided suitable by selection and exception standard, after take a medical experiment and checkup according to clinical trial plan. Registered subject should valuated by settled schedule after take the testing medicine 1,2 during thirty-day. In this period, a subject allocated at relatively better suited experimental group by oriental doctor after consideration of general efficacy and nature of a medicine at second visiting. Results: The result of comparison in the remedial value with sixteen patients who ended the experiment is like next list. 1. There's no regarded difference of comparison in general conditions between two patient groups. 2. There's no regarded difference during observation period before take medicine. 3. By period of measurement, there's something regarded differences most of patients of two parts after taking medicine. 4. There's no regarded difference at alteration phase of each standard according to kind of medicine. 5. There's no abnormal views reflected at allergy, Laboratory and Physical Examination during experiment. Conclusion: This experiment evidence a Dangguijakyak-san and Gyejibongnyeong-hwan can help for improvement generally life quality of postmenopausal women and certify safety of herbs.

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Examples of Holistic Good Practices in Promoting and Protecting Mental Health in the Workplace: Current and Future Challenges

  • Sivris, Kelly C.;Leka, Stavroula
    • Safety and Health at Work
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    • v.6 no.4
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    • pp.295-304
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    • 2015
  • Background: While attention has been paid to physical risks in the work environment and the promotion of individual employee health, mental health protection and promotion have received much less focus. Psychosocial risk management has not yet been fully incorporated in such efforts. This paper presents good practices in promoting mental health in the workplace in line with World Health Organization (WHO) guidance by identifying barriers, opportunities, and the way forward in this area. Methods: Semistructured interviews were conducted with 17 experts who were selected on the basis of their knowledge and expertise in relation to good practice identified tools. Interviewees were asked to evaluate the approaches on the basis of the WHO model for healthy workplaces. Results: The examples of good practice for Workplace Mental Health Promotion (WMHP) are in line with the principles and the five keys of the WHO model. They support the third objective of the WHO comprehensive mental health action plan 2013-2020 for multisectoral implementation of WMHP strategies. Examples of good practice include the engagement of all stakeholders and representatives, science-driven practice, dissemination of good practice, continual improvement, and evaluation. Actions to inform policies/legislation, promote education on psychosocial risks, and provide better evidence were suggested for higher WMHP success. Conclusion: The study identified commonalities in good practice approaches in different countries and stressed the importance of a strong policy and enforcement framework as well as organizational responsibility for WMHP. For progress to be achieved in this area, a holistic and multidisciplinary approach was unanimously suggested as a way to successful implementation.

Latissimus dorsi detrusor myoplasty for bladder acontractility: a systematic review

  • Forte, Antonio Jorge;Boczar, Daniel;Huayllani, Maria Tereza;Moran, Steven;Okanlami, Oluwaferanmi O.;Ninkovic, Milomir;Broer, Peter N.
    • Archives of Plastic Surgery
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    • v.48 no.5
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    • pp.528-533
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    • 2021
  • Bladder acontractility affects several thousand patients in the United States, but the available therapies are limited. Latissimus dorsi detrusor myoplasty (LDDM) is a therapeutic option that allows patients with bladder acontractility to void voluntarily. Our goal was to conduct a systematic review of the literature to determine whether LDDM is a better option than clean intermittent catheterization (CIC) (standard treatment) in patients with bladder acontractility. On January 17, 2020, we conducted a systematic review of the PubMed/MEDLINE, Cochrane Clinical Answers, Cochrane Central Register of Controlled Trials, Embase, and ClinicalTrials.gov databases, without time frame limitations, to identify articles on the use of LDDM for bladder acontractility. Of 75 potential articles, 4 fulfilled the eligibility criteria. The use of LDDM to treat patients with bladder acontractility was reported in four case series by the same group in Europe. Fifty-eight patients were included, and no comparison groups were included. The most common cause of bladder acontractility was spinal cord injury (n=36). The mean (±standard deviation) operative time was 536 (±22) minutes, postoperative length of hospital stay ranged from 10 to 13 days, and follow-up ranged from 9 to 68 months. Most patients had complete response, were able to void voluntarily, and had post-void residual volume less than 100 mL. Although promising outcomes have been obtained, evidence is still weak regarding whether LDDM is better than CIC to avoid impairment of the urinary tract among patients with bladder acontractility. Further prospective studies with control groups are necessary.

Cross-cultural adaptation and validation of the Turkish Yellow Flag Questionnaire in patients with chronic musculoskeletal pain

  • Koc, Meltem;Bazancir, Zilan;Apaydin, Hakan;Talu, Burcu;Bayar, Kilichan
    • The Korean Journal of Pain
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    • v.34 no.4
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    • pp.501-508
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    • 2021
  • Background: Yellow flags are psychosocial factors shown to be indicative of long-term chronicity and disability. The purpose of the study was to evaluate the psychometric properties of the Turkish Yellow Flag Questionnaire (YFQ) in patients with chronic musculoskeletal pain (CMP). Methods: The cross-cultural adaptation was conducted with translation and back-translation of the original version. Reliability (internal consistency and test-retest) was examined for 231 patients with CMP. Construct validity was assessed by correlating the YFQ with the Hospital Anxiety and Depression Scale (HADS), Orebro Musculoskeletal Pain Questionnaire (OMPQ), and Tampa Kinesiophobia Scale (TKS). Factorial validity was examined with both exploratory and confirmatory factorial analysis. Results: The YFQ showed excellent test/retest reliability with an Intraclass correlation coefficient of 0.82. The internal consistency was moderate (Cronbach's alpha of 0.797). As a result of the exploratory factor analysis, there were 7 domains compatible with the original version. As a result of confirmatory factor analysis, the seven-factor structure of YFQ was confirmed. There was a statistically significant correlation between YFQ-total score and OMPQ (r = 0.57, P < 0.001), HADS-anxiety (r = 0.32, P < 0.001), HADS-depression (r = 0.44, P < 0.001), and TKS (r = 0.37, P < 0.001). Conclusions: This study's results provide considerable evidence that the Turkish version of the YFQ has appropriate psychometric properties, including test-retest reliability, internal consistency, construct validity and factorial validity. It can be used for evaluating psychosocial impact in patients with CMP.

Analysis of Comparison between Seo Jungjoo Shiseon and Shillacho (『서정주(徐廷柱) 시선(詩選)』과 『신라초(新羅抄)』의 비교분석 - 무속적 상상력을 중심으로)

  • Lee, Young Kwang
    • Cross-Cultural Studies
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    • v.26
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    • pp.321-351
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    • 2012
  • This paper attempts to clarify the similarity found in Seo Jungjoo's two books of poems, Seo Jungjoo Shiseon and Shillacho, and thereby to establish the continuity between Seo's early poetry and his mid-period poetry. This attempt arises from the realization that unfamiliar poetic material, background, and narration are merely surface features, and that in fact his early concerns nevertheless persist in terms of his poetic imagination and his Weltanschauung. Furthermore, this continuity seems to originate from shamanistic spiritual chaos that is consubstantially interrelated with the spirit of his deceased lover. After chaos and confusion subsided, the poet's endeavor to discover the lineal origin of his personal shamanism shows itself in Seo Jungjoo Shiseon, and we witness the embodiment of such endeavor in Shillacho. His interest in the skies as it is expressed in my poem, and Shilla as it is intimated by Gwanghwamun are sublimated in saso yeonjag and the words of Queen Seondeog into shamanic wisdom that served as the norm for both spiritual life and physical life in ancient times, and the wisdom is carried on further into the present in Seo's own times. Moreover, the star and the bell sound that were presented as signs of desirable Weltanschauung in Sangrigwawon are transformed into the symbols of shamanic wisdom, and into the inner magic formula that contributes to achieving the wisdom. This analysis offers as its result the evidence embedded in his poems that shows, first, that the two books correspond to merely two separate stages of his poetic concern, and second, that his early poetic concern persists, though transformed through a peculiar manner, into his mid-period poems.

The Review of Metabolic Acidosis During Exercise (운동 시 대사적 산성화에 관한 고찰)

  • Yoon, Byung-Kon
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.4
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    • pp.1433-1441
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    • 2018
  • The development of acidosis during intense exercise has traditionally been explained by the increased production of lactic acid which causes the release of a proton and the formation of the acid salt sodium lactate. Through this explanation, when the rate of lactate production is high enough to exceed cellular proton buffering capacity, cellular pH is decreased. This biochemical process has been termed lactic acidosis. This belief has been an interpretation that lactate production causes acidosis and fatigue during intense exercise. However, this review provides clear evidence that there is no biochemical support for lactate production causing acidosis and fatigue. Metabolic acidosis is caused by an increased reliance on nonmitochondrial ATP turnover. Lactate production is essential for muscle to produce cytosolic $NAD^+$ to support continued ATP regeneration from glycolysis. In addition, Lactate production consumes protons. Although lactate accumulation can be a good indirect indicator for decreased cellular and blood pH, that is not direct causing acidosis.

Workplace Diesel Exhausts and Gasoline Exposure and Risk of Colorectal Cancer in Four Nordic Countries

  • Talibov, Madar;Sormunen, Jorma;Weiderpass, Elisabete;Kjaerheim, Kristina;Martinsen, Jan-Ivar;Sparen, Per;Tryggvadottir, Laufey;Hansen, Johnni;Pukkala, Eero
    • Safety and Health at Work
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    • v.10 no.2
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    • pp.141-150
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    • 2019
  • Background: Evidence on associations between occupational diesel exhaust and gasoline exposure and colorectal cancer is limited. We aimed to assess the effect of workplace exposure to diesel exhaust and gasoline on the risk of colorectal cancer. Methods: This case-control study included 181,709 colon cancer and 109,227 rectal cancer cases diagnosed between 1961 and 2005 in Finland, Iceland, Norway, and Sweden. Cases and controls were identified from the Nordic Occupational Cancer Study cohort and matched for country, birth year, and sex. Diesel exhaust and gasoline exposure values were assigned by country-specific job-exposure matrices. Odds ratios and 95% confidence intervals were calculated by using conditional logistic regression models. The results were adjusted for physical strain at work and occupational exposure to benzene, formaldehyde, ionizing radiation, chlorinated hydrocarbons, chromium, and wood dust. Results: Diesel exhaust exposure was associated with a small increase in the risk of rectal cancer (odds ratio - 1.05, 95% confidence interval 1.02-1.08). Gasoline exposure was not associated with colorectal cancer risk. Conclusion: This study showed a small risk increase for rectal cancer after workplace diesel exhaust exposure. However, this finding could be due to chance, given the limitations of the study.

A Clinical Research Analysis of the Korean Medicine for Peroneal Nerve Palsy (비골신경마비에 대한 국내 한의치료 임상연구 동향 분석)

  • Hong, Su Min;Lee, Eun Jung
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.3
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    • pp.61-74
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    • 2019
  • Objectives This study aimed to review clinical studies about Korean medicine used in peroneal nerve palsy. Methods In 11 online databases (Earticle, Research Information Sharing Service, Oriental Medicine Advanced Searching Integrated System, KMbase, Korean Traditional Knowledge Portal, National Digital Science Library, MEDLINE/Pubmed, Ebscohost, Cochrane CENTRAL, EMBASE, China National Knowledge Infrastructure), we searched clinical studies about Korean medicine. Among the studies that we've searched, we excluded the studies that are not related to Korean medicine, case reports, randomized controlled trials and retrospective studies. As a result, 16 case studies and 1 randomized controlled trial are included. Results Total number of patients was 123. In these studies, acupuncture (100%), herbal medicine (58.8%), pharmacopuncture (58.8%), Korean physical therapy (58.8%), moxibustion (41.1%), cupping (41.1%) etc. were used. In acupuncture, GB34 and ST36 were most frequently used. Most of the herbal medicines used in these studies were different. Range of movement were most frequently used in outcome measure. Conclusions In this study, we reviewed studies about Korean medicine used in peroneal nerve palsy. It was difficult to clearly determine which intervention has improved the symptom. In the future, Further clinical studies will be needed to retain the evidence for the treatment of peroneal nerve palsy. And also more randomized controlled clinical trials to prove the efficacy of Korean medicine will be needed.

On the Global and Local Environmental Dependence of Type Ia Supernova Luminosity from the Analysis of SALT2 and MLCS2k2 Light-Curve Fitters

  • Kim, Young-Lo;Lee, Young-Wook
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.1
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    • pp.40.3-40.3
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    • 2019
  • There is growing evidence for the dependence of Type Ia supernova (SN Ia) luminosities on the environments. The origin of this correlation, however, is under debate. In order to explore the physical origin of the trend in detail, we analyze SN Ia light-curves by combining a sample of 1231 SNe Ia over a wide redshift range (0.01 < z < 1.37) in various SN surveys and employing two independent light-curve fitters of SALT2 and MLCS2k2. Although SALT2 is the most widely used fitter in the SN community, MLCS2k2 has a novelty in the context of an investigation of the luminosity evolution of SNe Ia. For this reason we use both fitters and analyze them separately. We also determine a stellar mass and a star formation rate (SFR) for a sample of ~600 host galaxies. In addition, because recent low-redshift studies suggest that this dependence manifests itself most strongly when using the local SFR at the SN location, we introduce a new method to infer the local environments by restricting the SN Ia sample in globally star-forming host galaxies to a low-mass host galaxy subset (${\leq}10^{10}M_{\odot}$). We find that SNe Ia in low-mass and star-forming host galaxies are fainter than those in high-mass and passive hosts, after light-curve corrections. Especially, for the first time in host studies, we show that SNe Ia in locally star-forming environments are $0.081{\pm}0.018$ mag fainter ($4.5{\sigma}$) than those in locally passive environments from the sample including SNe at the high-redshift range. Considering the significant difference in the mean stellar population age between these environments, the result would suggest that the origin of the environmental dependence is the luminosity evolution of SNe Ia.

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