• Asian-Australasian Journal of Animal Sciences
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• v.17 no.9
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• pp.1260-1265
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• 2004

This research was conducted to compare the effects of vitamin E (VE) when supplemented in either feed or water on the performance and meat quality of broilers. For a six-week feeding trial, a total of 330 broiler chicks were allotted to five treatments. The treatments were 1) 0 ppm VE, 2) 10 ppm VE in feed, 3) 20 ppm VE in feed, 4) 5 ppm VE in water and 5) 10 ppm VE in water. During the starter phase (0-3 weeks) chicks on non-supplemented groups grew slower (p<0.05) than the supplemented ones and the same trend was followed during the finisher (4-6 weeks) and overall period (0-6 weeks). The feed intake was significantly higher in feed supplemented groups as compared with water-supplemented groups and at higher levels as compared with lower levels of supplementation. The nutrient digestibility studies conducted after 15 and 35 days on the feeding trial showed that the digestibility of all nutrients was significantly (p<0.05) higher in supplemented groups than the non-supplemented one. The dressing percentage was higher in supplemented groups, when fed in feed and at higher levels when compared with their respective counterparts. Similar trends were noticed with respect to bone resistance. The calcium and phosphorus contents in tibia were also significantly (p<0.05) higher in supplemented, feed fed groups at higher levels than other groups. The TBARS values measured after 5 and 10 days of storage, which reflect the degree of oxidation, showed significantly lower levels in supplemented diets. The plasma and muscle vitamin E levels also showed a positive linear correlation with the levels supplemented both in feed and water. Overall it can be inferred that supplementation of VE was beneficial and there was not much difference observed when fed either in feed or water at the levels measured in the present study.

• Biomedical Science Letters
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• v.15 no.4
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• pp.281-286
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• 2009

We found previously that Undaria pinnatifida extract has an effect of lowering blood glucose levels in diabetic rats. Therefore, an effect of Undaria pinnatifida extract on the insulin secretion directly from the pancreas was examined in this study. Neonatal diabetes were induced by intraperitoneal injection of Streptozotocin (100 mg/kg body weight) at age of day 1. Rats were fed a rodent pellet diet until they were grown to adults (age of 7 weeks). Rats having a fasting serum glucose level over 250 mg/dL were used in this feeding study and they were divided into two diet groups as follows; a diet with Undaria pinnatifida extract (5%) and a diet without this extract (control group). Fasting (12 hr) blood glucose and serum insulin levels were measured before and after feeding a diet with Undaria pinnatifida extract for 4 weeks. At the last day of feeding, in vitro pancreas perfusion was performed. Pancreas was stimulated with a perfusate without glucose during a period of 0~10 minutes and with a perfusate containing 200 mg/dL glucose during a period of 11~40 minutes. Insulin amount was measured using a radioimmuno assay. In results, amount of the insulin secreted from the pancreas in the diabetic rats fed Undaria pinnatifida extract was significantly greater than that in the diabetic control group during the periods of the equilibration period (0~10 min) and the first phase (11~20 min) of the insulin secretion (P<0.05). It is concluded that Undaria pinnatifida extract increases insulin secretion from the pancreas in the neonatal diabetic rats. Therefore, the blood glucose lowering effect of the Undaria pinnatifida extract may be elucidated by mechanisms with promoted insulin secretion from the pancreas in diabetic rats.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.18 no.9
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• pp.1005-1014
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• 2007

In this paper, The four types SRA(Sequential Rotated Array) antennas has been analyzed. Those are consisted of a 4-elements SRA, a 8-elements SRA, the $2{\times}2$ planer array SRA and the triple (4+8+4)-elements SRA. These LHCP SRA antennas are used a probe feeding multi-layer truncated microstrip antenna whose center frequency is 11.85 CHz. The cooperated feeding circuits are designed for feeding to each elements with equal amplitude and regular phase. Comparing with the each simulation results and experiment results of this 4-type SRA antennas, the triple (4+8+4)-elements SRA showed the most electrical characteristics in the degree of integration, high gain and low cross polarization.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2006.06a
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• pp.521-522
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• 2006

In this paper, hybrid air-water discharges were used to develop an optimal condition for providing a high level of water decomposition for hydrogen yield. Electrical and optical phenomena accompanying the discharges were investigated along with feeding gases, flow rates, and point-to-plane electrode gap distance. The primary focus of this experiment was put on the optical emission of the near UV range, with the energy threshold sufficient for water dissociation and excitation. The $OH(A^{2+},'=0\;X^2,"=0$) band's optical emission intensity indicated the presence of plasma chemical reactions involving hydrogen formation. In the gaseous atmosphere saturated with water vapor the OH(A-X) band intensity was relatively high compared to the liquid and transient phases although the optical emission strongly depended on the flow rate and type of feeding gas. In the gaseous phase discharge phenomenon for Ar carrier gas transformed into a gliding arc via the flow rate growth. OH(A-X) band's intensity increased according to the flow rate or residence time of He feeding gas. Reciprocal tendency was acquired for $N_2$ and Ar carrier gases. The peak value of OH(A-X) intensity was observed in the proximity of the water surface, however in the cases of Ar and $N_2$ with 0.5 SLM flow rate peaks shifted to the region below the water surface. Rotational temperature ($T_{rot}$) was estimated to be in the range of 900-3600 K, according to the carrier gas and flow rate, which corresponds to the arc-like-streamer discharge.

• Journal of Veterinary Science
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• v.21 no.5
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• pp.60.1-60.11
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• 2020

Background: Tumor-associated neoangiogenesis is a crucial target for antitumor therapies. Thalidomide (TAL) is a promising anti-neoangiogenetic drug that has recently been used in the treatment of several malignancies in dogs. Objectives: The aim of the study was to assess the pharmacokinetics of TAL after single oral administration in dogs. Additionally, the influence of feeding on the pharmacokinetic profile of TAL in dogs has been preliminarily investigated. Methods: Six healthy adult female Labradors were enrolled according to a randomized single-dose, 2-treatment, 2-phase, paired 2 × 2 cross-over study design. The dogs were administered a single 400 mg capsule of TAL in fasted and fed conditions. Blood was collected from 15 min to 48 h after dosing, and TAL quantified in plasma by a validated high-performance liquid chromatography method. The pharmacokinetics of TAL were analyzed using a non-compartmental approach. Results: TAL concentration was quantifiable up to 10 h and 24 h after fasted and fed conditions, respectively. C_max (fasted, 1.34 ± 0.12 ㎍/mL; fed, 2.47 ± 0.19 ㎍/mL) and T_max (fasted, 3 h; fed, 10 h) differed substantially between the 2 groups. AUC and t_1/2λz were significantly higher in fed (42.46 ± 6.64 mg × h/L; 17.14 ± 4.68 h) compared to fasted (12.38 ± 1.13 mg × h/L; 6.55 ± 1.25 h) dogs. The relative oral bioavailability of TAL for the fasted group was low (36.92% ± 3.28%). Conclusions: Feeding affects the pharmacokinetics of oral TAL in dogs, showing a delayed, but higher absorption with different rate of elimination. These findings are of importance in clinical veterinary settings, and represent a starting point for further related studies.

• Clinical Nutrition Research
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• v.13 no.1
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• pp.1-7
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• 2024

Nutritional support in critically ill patients is an essential aspect of treatment. In particular, the benefits of enteral nutrition (EN) are well recognized, and various guidelines recommend early EN within 48 hours in critically ill patients. However, there is still controversy regarding EN in critically ill patients with septic shock requiring vasopressors. Therefore, this case report aims to provide basic data for the safe and effective nutritional support in septic shock patients who require vasopressors. A 62-year-old male patient was admitted to the intensive care unit with a deep neck infection and mediastinitis that progressed to a septic condition. Mechanical ventilation was initiated after intubation due to progression of respiratory acidosis and deterioration of mental status, and severe hypotension required the initiation of norepinephrine. Due to hemodynamic instability, the patient was kept nil per os. Subsequently, trophic feeding was initiated at the time of norepinephrine dose tapering and was gradually increased to achieve 75% of the energy requirement through EN by the 7th day of enteral feeding initiation. Although there were signs of feeding intolerance during the increasing phase of EN, adjusting the rate of EN resolved the issue. This case report demonstrates the gradual progression and adherence to EN in septic shock patient requiring vasopressors, and the progression observed was relatively consistent with existing studies and guidelines. In the future, further case reports and continuous research will be deemed necessary for safe and effective nutritional support in critically ill patients with septic shock requiring vasopressors.

• Asian-Australasian Journal of Animal Sciences
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• v.16 no.10
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• pp.1455-1459
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• 2003

A $2{\times}3$ factorial design was used to study the impact of rearing systems, individual (I) vs. group (G) and different levels of milk/skim milk feeding (three schedules, F1, F2 and F3) on performance of crossbred (Bos indicus ${\times}$ Bos taurus) calves. Six calves (three from each sex) were taken in each group on the basis of their birth weight. All the calves were fed colostrum for three days and thereafter, were allotted to three different milk feeding schedules (F), i.e. milk fed upto 8 weeks of age (F1), milk upto 4 weeks followed by 50% (F2) and 100% (F3) replacement of milk with skim milk in the next 4 weeks. Calf starter and cereal green fodder were fed ad libitum to all the calves beginning from second week of age. A digestibility trial was conducted at 15th week of age to assess nutrient utilization during postweaning period. The digestibilty of dry matter (DM), organic matter, total carbohydrate, ether extract and crude protein (CP) were nonsignificant between the rearing systems and the feeding schedules. There was significantly higher digestibility of NDF and ADF in G than I and in F3 than F1 and F2. The concentration CP and total digestible nutrients of the diet ranged from 17.18 to 17.75% and 66.32 to 70.14%, respectively. The DM intake (kg/100 kg body weight) ranged from 1.74 to 2.14 kg during 0 to 8 weeks and 3.19 to 3.41 kg during 0 to 14 weeks of age. The effects during postweaning phase (9-14 weeks of age) showed increased performance in group housed calves compared to individually housed ones with a superior average daily gain (590 vs. 443 g) and dry matter intake (1.79 vs. 1.64 kg). Above all, replacement of milk with skim milk at 50% level after 4th week followed by complete removal after 6th week of age (F2) seemed to suit better in coping with immediate energy starvation due to sole feeding of skim milk (F3) and they performed the best under group housed system of rearing.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.28 no.3
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• pp.237-246
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• 1995

Larvae of the freshwater shrimp, Macrobrachium nipponense were reared in the laboratory at constant condition $(25^{\circ}C,\;7\%o)$, and their feeding rate, oxygen consumption rate, and growth rate were measured in regular intervals of time during larval development. Regression equations describing rates of feeding, growth and respiration as functions of time during individual larval molt cycles were inserted in a simulation model in order to analyse time-dependent patterns of variation as well as in bioenergetic efficiencies. Absolute values for feeding, growth, respiration and assimilation showed clear changes during the molt cycle, The absolute and specific values of respiration (R: R/C) showed small variation during the individual molt cycles. Significance of respiration in relation to growth (G) increased within the carbon budget, respiration rate (R/C) outbalanced growth rate (G/C) in late premolt. When the portion of metabolizable carbon is respired (R/G), metabolic coefficient was < 1 (i.e. R$(K_2)$ decreased concurrently, In cumulative carbon budget, total feeding was $491.54\;{\mu}g$ C/ind., assimilation was $85.3\%$, respiration was $47.7\%$, and growth was $37.6\%$ from hatching to postlarval stage.

• Asian-Australasian Journal of Animal Sciences
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• v.8 no.2
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• pp.129-133
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• 1995

A feeding trial was conducted to evaluate the effects of crude protein concentration (44% vs 48%) and extrusion processing of soybean meal (SBM) on the performance of weanling and growing pigs. One hundred and ninety two (96 pigs of each sex) 3 way crossed (Landrace ${\times}$ Hampshire ${\times}$ Duroc) weaned pigs were allotted to 12 pens each of 16 pigs (8 pigs of each sex). Three pens were assigned to each of the 4 treatment; $T_1$; 44% SBM diet, $T_2$; extruded 44% SBM diet, $T_3$; 48% SBM diet and $T_4$; extruded 48% SBM diet. The 44% SBM diet was formulated to have 18% CP for the starter phase (5-10 wk of age) and 15% CP for the grower phase (10-15 wk of age). The other treatments used equivalent amount of each SBM, replacing the 44% SBM. Chemical assay showed that extrusion processing generally decreased amino acid content especially total lysine and available lysine. Extrusion increased Hunterlab color +a value and decreased the urease activity index. The body weight gains for the $T_3$ and $T_4$ pigs were significantly(p < 0.05) greater than for those on $T_1$ and $T_2$ for the starter phase, but not the grower phase. Extrusion processing did not improve weight gain. Feed intake for the overall period was significantly(p < 0.05) different among treatments. The feed conversion ratios were not significantly different among treatments. An economic analysis showed that the high protein (48%) SBM diet was more cost effective than the low protein(44%) SBM diet, for the starter phase.

• Korean Journal of Poultry Science
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• v.28 no.3
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• pp.245-257
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• 2001

Localization of livestock facilities leads to concentration of livestock wastes and subsequent leakage of pollutants into the environment, resulting in public concern about their effects. Nitrogen (N) and phosphorus (P) are the most harmful components of animal manure, but odor from the manure itself and the livestock facilities is also a problem. Improving the nutrient efficiency of the livestock helps to decrease excretion of these environmental contaminants. Pigs and chickens are the main experimental models used in studies to improve nutrient efficiency. Addition of feed supplements and modifying feeding systems to improve nutrient efficiency can result in significant decrease in the N, P, odor and dry matter (DM) weight of manure. Examples of these methods include the following. 1) Addition of synthetic amino acids and reducing protein contents resulted N reductions of 10∼27% in broilers, 18∼35% in chicks and layers, 19∼62% in pigs, and a 9∼43% reduction in odor in pigs. 2) Enzyme supplementation resulted in a 12∼15% reduction in DM weight in broiler manure. 3) Phvtase supplementation resulted in P reductions of 25∼35% in chickens and 20∼60% in pigs. 4) Use of growth promoting substances resulted in a 5∼30% reduction in N and a 53∼56% reduction in odor of pigs. 5) Formulating diets closer to requirements (diet modification) reduced N and P by 10∼15% each in chickens and pigs, and odor by 28∼ 79% in pigs. 6) Phase feeding reduced N and P excretion by chicken and pigs from 10∼33% and 10∼13% each, as well as odor in growing and finishing pigs by 49∼79%. 7) Use of highly digestible raw materials in feed reduced N and P excretion by 5% in chickens and pigs.