• 제목/요약/키워드: pet care

검색결과 100건 처리시간 0.031초

Effect of Epidermal Growth Factor (EGF) on Meiotic Maturation and Pronuclear Formation of Porcine Oocytes Produced In Vitro

  • Song S. H.;Kim J. G.;Song H. J.;Kumar B. Mohana;Cho S. R.;Choe C. Y.;Choi S. H.;Rho G. J.;Choe S. Y.
    • Reproductive and Developmental Biology
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    • 제29권2호
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    • pp.127-131
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    • 2005
  • The objective of this study was to examine the effect of EGF on meiotic maturation and pronuclear (PN) formation of porcine oocytes. Prepubertal gilt cumulus-oocyte-complexes (COCs) aspirated from $2\~6mm$ follicles of abbatoir ovaries were matured in TCM199 containing 0.1mg/ml cysteine, $0.5{\mu}/ml$ FSH and LH, and EGF (0, 5, 10, 20, 40 ng/ml) for 22 hr at $39^{\circ}C$ in a humidified atmosphere of $5\%$ $CO_2$ in air. They were then cultured for an additional 22hr without hormones. In Experiment 1, to examine the nuclear maturation at 44hr of culture, the expanded cumulus cells were removed by vortexing for 1 min in 3 mg/ml hyaluronidase. The oocytes were fixed in acetic acid: methanol (1:3, v/v) at least for 48 hr and stained with $1\%$ orcein solution for 5 min. Nuclear status was classified as germinal vesicle (GV), germinal vesicle breakdown (GVBD), prophase-metaphase I (PI-MI), and PII-MII under microscope. In Experiment 2, to investigate PN formation, oocytes were fertilized with Percoll-treated freshly ejaculated sperm $(1\times10^5\; cells/ml)$ in mTBM with $0.3\%$ BSA and 2mM caffeine for 5hr, and cultured in NCSU-23 medium with $0.4\%$ BSA. At 6hr of culture, the embryos were fixed in $3.7\%$ formaldehyde for 48hr and stained with 10ug/ml propidium iodide for 30 min. PN status was classified as no or one PN (unfertilized), 2 PN (normal fertilized) and $\geq3$ PN (polyspermy). Differences between groups were analyzed using one-way ANOVA after arc-sine transformation of the proportional data. The rate of oocytes that had reached to PII-MII were significantly (P<0.05) higher in all groups added EGF than that of non-treated group $(67\%)$, but it did not differ among the all added groups $(86\%,\;85\%,\;79\%\;and\;81\%$, in 5, 10, 20 and 40 ng/ml EGF, respectively). No differences on the incidence of 2PN were observed in all treated groups $(25\%,\;30\%,\;33\%,\;29\%\;and\;29\%$, in 0, 5, 10, 20 and 40 ng/ml EGF, respectively), however, in non-treated group, polyspermy tended to be increased ($66\%\;vs\;. 58\%,\;54\%,\;52\%\;and\;55\%$, 0 vs. 5, 10, 20, 40 ng/ml EGF, respectively). These results suggest that EGF can be effectively used as an additive for enhancing oocyte maturation and reducing the incidence of polyspermy in pig.

북방 참매에서 발생한 Bumble foot의 성공적인 치료 증례 (Successful Treatment of Severe Bumble foot in a Northern Goshawk (Accipiter gentilis))

  • 정태호;오승국;김정현;김현주;박철
    • 한국임상수의학회지
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    • 제32권3호
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    • pp.268-271
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    • 2015
  • 2년 령 수컷 북방 참매 (대한민국 천연기념물 323-1호 지정)가 지간부위 통증, 부종 및 파행을 주호소로 내원하였다. 북방 참매는 지역 농가에서 구조되어 2주정도 자가 치료를 하였으나 상태가 악화되어 본원에 내원하였다. 신체검사 상 양쪽 발에서 발바닥 지간염과 4번째 발가락의 허약 증상을 보였다. 방사선학적 검사에서 발바닥 연부조직의 부종성 병변과 뼈의 융해 소견이 관찰되었으며, 분야별 복합적인 접근을 토대로 3기 bumble foot으로 진단되었다. 창상 부위의 삼출물 배양을 실시하는 동시에 항생제 감수성 검사를 수행하였다. 배양 결과 분리 균주는 Staphylococcus aureus로 확인되었으며 Amikacin이 감수성이 있는 것으로 확인되었다. 우선적으로 병변 부위를 절제하여 괴사된 부분을 제거한 후 세척하고 배액한 후 국소적으로 광범위 항생제인 뮤피로신 연고제를 도포한 다음 볼붕대법으로 유지 및 소독, 배액을 실시하였다. 3주 동안의 집중적인 치료를 통해 상처 부위는 완전히 치유되었지만, 후유증으로 양쪽 발 4번째 발가락의 지지력이 약해졌다. 치료 시작 8주 후 북방 참매는 자연으로 방사되었다.

양돈농가의 경영관리 및 분뇨처리실태 분석 (Analysis of Current Situation for Management Skill and Manures Treatment in Pig Farms)

  • 김계웅;인광교;신연호
    • 한국축산시설환경학회지
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    • 제18권1호
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    • pp.35-44
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    • 2012
  • 본 조사연구는 충남의 번식돈과 비육돈 농장을 포함한 전업규모 100개 양돈장을 대상으로 경영관리 실태와 분뇨처리 시스댐을 조사 분석하여 합리적인 경영관리 지표설정과 적정 분뇨처리시스템 모델 개발에 필요한 기초척 자료를 얻고자 실시한 결과를 요약하면 다음과 같다. 첫째는, 양돈장 경영관리중 평균 전문컨설팅 참여는 1년에 "4.56회"를 받는 것으로 조사되었고, 농장별 및 경력층간에는 유의한 차이없이 비슷한 수준으로 교육참여횟수를 보였다. 백신예방접종프로그램은 5점 만점 중 "3.86점"으로 보통이상 수준이었다. 번식돈과 비육돈 농장간에는 유의한 차이를 보였는데, 번식돈 농장이 4.13점으로 비육돈 농장 3.63점 보다 유의하게(p<0.01) 우수한 성적을 보였다. 방역위생관리는 평균 "3.27점"으로 보통수준으로 관리되고 있으며, 농장간에는 번식돈농장이 3.50점으로 비육돈 농장 3.07점 보다 유의하게(p<0.01) 양호한 관리상태를 보였다. 자금관리는 평균 "2.82점"으로 보통 이하 수준으로 운영되고 있어 사업계획이나 자금경영관리를 연간수요에 따라 집행되어야 할 것이다. 그리고 기술력 보유수준은 평균 "3.21점"으로 보통이상의 수준으로 평가 되었는데, 장차 축산국가와의 FTA 등에 대비한 기술 경쟁력확보에 최선을 다해야 할 것으로 생각된다. 둘째는, 양돈장에서 경쟁력 강화분야로는 "돼지의 질병과 치료"를 가장 희망하였고(43.4%), 그 다음은 친환경 생산관리(37.4%) 기술을 더욱 강화해야 할 것으로 뽑고 있었다. 셋째는, 양돈장의 분뇨수거시스템은 대부분의 농장에서 "슬러리시스템(44.0%)과 스크래퍼법(43.0%)"으로 돼지분뇨를 수거하는 것으로 조사되었는데, 농장여건에 따라 적절한 수거 시스템을 설치하여 활용하는 것이 바람직 할 것으로 사료된다. 넷째는, 돼지 분뇨처리는 많은 농장에서 "수거후 경지환원"을 가장 많이 이용(32.3%)하는 것으로 나타나, 분뇨의 저장기간, 온도, 방법 등 효율적인 처리방법과 적정 작목선정을 통한 경지환원이 이루어져야 할 것으로 판단된다. 앞으로는 친환경 자연순환시스템으로 경지에 환원하여 지력보전과 함께 우량 경종작물이 성장 할 수 있도록 자연순환형 분뇨처리와 이용 시스템이 구축되어야 할 것으로 생각된다.

개에서 케타민-자일라진 마취동안 심박변이도에 대한 아트로핀과 글리코피롤레이트의 자율신경적 특성 (Autonomic Nervous Properties of Atropine and Glycopyrrolate on Heart Rate Variability during Anesthesia with Ketamine-Xylazine in Dogs)

  • 박우영;배춘식;이수한;박우대
    • 한국임상수의학회지
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    • 제26권3호
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    • pp.212-219
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    • 2009
  • 개의 마취에서 부작용을 예방하기 위하여 전마취제로 가장 일반적으로 사용되어지는 항콜린제는 심장에 부작용을 일으킬 수 있다. 비글견에서 케타민 마취 동안 심장의 교감신경과 부교감 신경의 균형에 대한 아트로핀과 글리코피롤레이트의 효과를 검증하기 위하여, 심박변이도, 마취 기간 그리고 행동 변화가 평가 되어졌다. 아트로핀과 글리코피롤레이트에서는 어떠한 일시적인 domain 차이도 없었다. 주파수 영역과 연관되어서는, 아트로핀과 글리코피롤레이트 효과는 모두 대조군에 비해 유의하게 낮게 나타났다(P<0.05). 그러나, 아트로핀의 RMSSD와 SD1은 기준선보다 낮았으며(P<0.05), 글리코피롤레이트의 LF:HF ratio는 기준선보다 높은 유의한 변화를 보였다(P<0.05). SD1의 변화는 주파수 도메인의 HF와 일치하는 변화를 보였으며 호흡수와 $SpO_2-R$의 변화와도 일치하는 변화를 보였다. 우리의 결과는 심장의 자율신경적 특성을 이용하여 글리코피롤레이트가 안전성과 작용 시간을 고려하여 개에서 케타민 마취 시 항콜린제로 더욱 적당하다는 것을 증명한 것이다.

우유 대체 식물성 기반 우유 유사체 개발에 관한 현황과 미래 (Development of Plant-Based Milk Analogues as Alternatives to Cow Milk: Current Status and Future Prospects)

  • 김태진;서건호;천정환;윤혜영;김현진;김영선;김빈;정동관;송광영
    • Journal of Dairy Science and Biotechnology
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    • 제39권4호
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    • pp.129-144
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    • 2021
  • Following the COVID-19 pandemic, many people are increasingly becoming interested in health and environmental issues. Therefore, the sale of vegan or vegetarian products has been increasing over the last few years, as well as interest in non-dairy plant-based milk that can replace cow's milk. Furthermore, the global food industry has developed an interest in such products, considering the recent changes in consumer trends. In Korea, various products are being launched annually due to the increasing interest in non-dairy plant-based milk. However, research with regard to the quality and type of products produced in Korea is still at the preliminary stage when compared to those in the United States and Europe. Therefore, the present review has summarized non-dairy plant-based milk analogues based on the following key aspects. First, the types of non-dairy plant-based milk analogues and their production technologies (in the order of almond milk > cocoa milk > coconut milk > hemp milk > kidney bean milk > oat milk > peanut milk > rice milk, and soy milk). Second, the current status and future prospects for non-dairy plant-based milk analogues. Third, recent trends and future challenges associated with the production and quality improvement of non-dairy plant-based milk analogues. Fourth, the current status and outlook of the non-dairy plant-based milk analogue market in Korea. In conclusion, the present review could provide the food industry with valuable information regarding non-dairy plant-based milk analogues to facilitate the development of related products. Data were obtained from previously published studies.

개에서 전기제모술을 이용한 첩모중생의 치료 1례 (A case of distichiasis treatment using electroepilation in a dog)

  • 강명곤;한동현;한세명;정은겸;김경민;이신호;신윤주;강주빈;이동빈;고필옥;조재현;원청길;김충희
    • 한국동물위생학회지
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    • 제45권4호
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    • pp.325-330
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    • 2022
  • Distichiasis is one of the diseases commonly encountered in companion animals, and these abnormal eyelashes cause corneal ulcers, continuous eye irritation, eye pain, glare, epiphora, foreign body sensation and can cause corneal opacity and vision loss in severe cases. In this study, an eyelash epilation needle for animals was developed and applied to a real case, and the results were observed. In a case of corneal ulcer caused by distichiasis of a 2-year-old Shih Tzu, a high-frequency surgical instrument for animals was converted into an electric epilation needle to attempt a procedure to destroy the eyelash hair follicles on the upper eyelid. A epilation needle was developed to have a diameter of 0.1 mm and a length of 4 mm at the end of the handle of DOCTANZ 400, an electrosurgical instrument for animals only. In the procedure, 2~3 mm of an epilation needle was inserted into the hair follicle, and 1 watt of electric power was applied to the hair follicle for about 5 sec. to carry out electrolysis until white bubbles were generated around the meibomian glands thereby destroying the hair follicle. As a result, no eyelashes grew any longer in the treated area indicating that the treatment was successful. It is hoped that the method developed in this study will be applied so that it will be widely used as a treatment method for distichiasis in companion animals that can be frequently seen hereafter.

병원 간호행정 개선을 위한 연구 (A Study for Improvement of Nursing Service Administration)

  • 박정호
    • 대한간호학회지
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    • 제3권1호
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    • pp.13-40
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    • 1972
  • Much has teed changed in the field of hospital administration in the It wake of the rapid development of sciences, techniques ana systematic hospital management. However, we still have a long way to go in organization, in the quality of hospital employees and hospital equipment and facilities, and in financial support in order to achieve proper hospital management. The above factors greatly effect the ability of hospitals to fulfill their obligation in patient care and nursing services. The purpose of this study is to determine the optimal methods of standardization and quality nursing so as to improve present nursing services through investigations and analyses of various problems concerning nursing administration. This study has been undertaken during the six month period from October 1971 to March 1972. The 41 comprehensive hospitals have been selected iron amongst the 139 in the whole country. These have been categorized according-to the specific purposes of their establishment, such as 7 university hospitals, 18 national or public hospitals, 12 religious hospitals and 4 enterprise ones. The following conclusions have been acquired thus far from information obtained through interviews with nursing directors who are in charge of the nursing administration in each hospital, and further investigations concerning the purposes of establishment, the organization, personnel arrangements, working conditions, practices of service, and budgets of the nursing service department. 1. The nursing administration along with its activities in this country has been uncritical1y adopted from that of the developed countries. It is necessary for us to re-establish a new medical and nursing system which is adequate for our social environments through continuous study and research. 2. The survey shows that the 7 university hospitals were chiefly concerned with education, medical care and research; the 18 national or public hospitals with medical care, public health and charity work; the 2 religious hospitals with medical care, charity and missionary works; and the 4 enterprise hospitals with public health, medical care and charity works. In general, the main purposes of the hospitals were those of charity organizations in the pursuit of medical care, education and public benefits. 3. The survey shows that in general hospital facilities rate 64 per cent and medical care 60 per-cent against a 100 per cent optimum basis in accordance with the medical treatment law and approved criteria for training hospitals. In these respects, university hospitals have achieved the highest standards, followed by religious ones, enterprise ones, and national or public ones in that order. 4. The ages of nursing directors range from 30 to 50. The level of education achieved by most of the directors is that of graduation from a nursing technical high school and a three year nursing junior college; a very few have graduated from college or have taken graduate courses. 5. As for the career tenure of nurses in the hospitals: one-third of the nurses, or 38 per cent, have worked less than one year; those in the category of one year to two represent 24 pet cent. This means that a total of 62 per cent of the career nurses have been practicing their profession for less than two years. Career nurses with over 5 years experience number only 16 per cent: therefore the efficiency of nursing services has been rated very low. 6. As for the standard of education of the nurses: 62 per cent of them have taken a three year course of nursing in junior colleges, and 22 per cent in nursing technical high schools. College graduate nurses come up to only 15 per cent; and those with graduate course only 0.4 per cent. This indicates that most of the nurses are front nursing technical high schools and three year nursing junior colleges. Accordingly, it is advisable that nursing services be divided according to their functions, such as professional, technical nurses and nurse's aides. 7. The survey also shows that the purpose of nursing service administration in the hospitals has been regulated in writing in 74 per cent of the hospitals and not regulated in writing in 26 per cent of the hospitals. The general purposes of nursing are as follows: patient care, assistance in medical care and education. The main purpose of these nursing services is to establish proper operational and personnel management which focus on in-service education. 8. The nursing service departments belong to the medical departments in almost 60 per cent of the hospitals. Even though the nursing service department is formally separated, about 24 per cent of the hospitals regard it as a functional unit in the medical department. Only 5 per cent of the hospitals keep the department as a separate one. To the contrary, approximately 12 per cent of the hospitals have not established a nursing service department at all but surbodinate it to the other department. In this respect, it is required that a new hospital organization be made to acknowledge the independent function of the nursing department. In 76 per cent of the hospitals they have advisory committees under the nursing department, such as a dormitory self·regulating committee, an in-service education committee and a nursing procedure and policy committee. 9. Personnel arrangement and working conditions of nurses 1) The ratio of nurses to patients is as follows: In university hospitals, 1 to 2.9 for hospitalized patients and 1 to 4.0 for out-patients; in religious hospitals, 1 to 2.3 for hospitalized patients and 1 to 5.4 for out-patients. Grouped together this indicates that one nurse covers 2.2 hospitalized patients and 4.3 out-patients on a daily basis. The current medical treatment law stipulates that one nurse should care for 2.5 hospitalized patients or 30.0 out-patients. Therefore the statistics indicate that nursing services are being peformed with an insufficient number of nurses to cover out-patients. The current law concerns the minimum number of nurses and disregards the required number of nurses for operation rooms, recovery rooms, delivery rooms, new-born baby rooms, central supply rooms and emergency rooms. Accordingly, tile medical treatment law has been requested to be amended. 2) The ratio of doctors to nurses: In university hospitals, the ratio is 1 to 1.1; in national of public hospitals, 1 to 0.8; in religious hospitals 1 to 0.5; and in private hospitals 1 to 0.7. The average ratio is 1 to 0.8; generally the ideal ratio is 3 to 1. Since the number of doctors working in hospitals has been recently increasing, the nursing services have consequently teen overloaded, sacrificing the services to the patients. 3) The ratio of nurses to clerical staff is 1 to 0.4. However, the ideal ratio is 5 to 1, that is, 1 to 0.2. This means that clerical personnel far outnumber the nursing staff. 4) The ratio of nurses to nurse's-aides; The average 2.5 to 1 indicates that most of the nursing service are delegated to nurse's-aides owing to the shortage of registered nurses. This is the main cause of the deterioration in the quality of nursing services. It is a real problem in the guest for better nursing services that certain hospitals employ a disproportionate number of nurse's-aides in order to meet financial requirements. 5) As for the working conditions, most of hospitals employ a three-shift day with 8 hours of duty each. However, certain hospitals still use two shifts a day. 6) As for the working environment, most of the hospitals lack welfare and hygienic facilities. 7) The salary basis is the highest in the private university hospitals, with enterprise hospitals next and religious hospitals and national or public ones lowest. 8) Method of employment is made through paper screening, and further that the appointment of nurses is conditional upon the favorable opinion of the nursing directors. 9) The unemployment ratio for one year in 1971 averaged 29 per cent. The reasons for unemployment indicate that the highest is because of marriage up to 40 per cent, and next is because of overseas employment. This high unemployment ratio further causes the deterioration of efficiency in nursing services and supplementary activities. The hospital authorities concerned should take this matter into a jeep consideration in order to reduce unemployment. 10) The importance of in-service education is well recognized and established. 1% has been noted that on the-job nurses. training has been most active, with nursing directors taking charge of the orientation programs of newly employed nurses. However, it is most necessary that a comprehensive study be made of instructors, contents and methods of education with a separate section for in-service education. 10. Nursing services'activities 1) Division of services and job descriptions are urgently required. 81 per rent of the hospitals keep written regulations of services in accordance with nursing service manuals. 19 per cent of the hospitals do not keep written regulations. Most of hospitals delegate to the nursing directors or certain supervisors the power of stipulating service regulations. In 21 per cent of the total hospitals they have policy committees, standardization committees and advisory committees to proceed with the stipulation of regulations. 2) Approximately 81 per cent of the hospitals have service channels in which directors, supervisors, head nurses and staff nurses perform their appropriate services according to the service plans and make up the service reports. In approximately 19 per cent of the hospitals the staff perform their nursing services without utilizing the above channels. 3) In the performance of nursing services, a ward manual is considered the most important one to be utilized in about 32 percent of hospitals. 25 per cent of hospitals indicate they use a kardex; 17 per cent use ward-rounding, and others take advantage of work sheets or coordination with other departments through conferences. 4) In about 78 per cent of hospitals they have records which indicate the status of personnel, and in 22 per cent they have not. 5) It has been advised that morale among nurses may be increased, ensuring more efficient services, by their being able to exchange opinions and views with each other. 6) The satisfactory performance of nursing services rely on the following factors to the degree indicated: approximately 32 per cent to the systematic nursing activities and services; 27 per cent to the head nurses ability for nursing diagnosis; 22 per cent to an effective supervisory system; 16 per cent to the hospital facilities and proper supply, and 3 per cent to effective in·service education. This means that nurses, supervisors, head nurses and directors play the most important roles in the performance of nursing services. 11. About 87 per cent of the hospitals do not have separate budgets for their nursing departments, and only 13 per cent of the hospitals have separate budgets. It is recommended that the planning and execution of the nursing administration be delegated to the pertinent administrators in order to bring about improved proved performances and activities in nursing services.

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Survival Results and Prognostic Factors in T4 N0-3 Non-small Cell Lung Cancer Patients According to the AJCC 7th Edition Staging System

  • Arslan, Deniz;Bozcuk, Hakan;Gunduz, Seyda;Tural, Deniz;Tattli, Ali Murat;Uysal, Mukremin;Goksu, Sema Sezgin;Bassorgun, Cumhur Ibrahim;Koral, Lokman;Coskun, Hasan Senol;Ozdogan, Mustafa;Savas, Burhan
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권6호
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    • pp.2465-2472
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    • 2014
  • Background: The American Joint Committee on Cancer (AJCC) published a new staging system ($7^{th}$ edition) in 2009. In our study, we evaluated the survival results and prognostic factors among T4 local advanced non-small cell lung cancer (LA-NSCLC) patients in a large heterogeneous group, in accordance with this new system. Materials and Methods: We retrospectively evaluated the files of 122 T4 N0-3 M0 LA-NSCLC patients, identified according to the new staging system, treated at two centers between November 2003 and June 2012. Variables correlating with univariate survival at p<0.20 were later included in multivariate Cox regression analysis. Here, selection of relevant predictors of survival was carried out in accordance with the likelihood ratio formula with p<0.05 regarded as significant. Results: The median age was 60 and the median follow-up period was 17.4 months. Median overall survival (OS) was 18.3 months, the 1 year overall survival (OS) rate was 72%, and the 5 year OS rate was 28%. Statistically significant predictors of survival were (p<0.20) ECOG-PS (Eastern Cooperative Oncology Group Performance Status), age, T4 factor subgroup, stage and primary treatment in OS univariate analysis. On multivariate analysis for OS ECOG-PS (p=0.001), diagnostic stage (p=0.021), and primary treatment (p=0.004) were significant. In the group receiving non-curative treatment, the median OS was 11.0 months, while it was 19.0 months in the definitive RT group and 26.6 months in the curative treatment group. There was a significant difference between the non-curative group and the groups which had definitive RT and curative operations (respectively p<0.001 and p=0.001) in terms of OS, but not between the groups which had definitive RT and curative operations. The median event free survival (EFS) rate was 9.9 months, with rates of 46% and 19% at 3 and 5 years, respectively. On univariate analysis of EFS rate with ECOG-PS, weight loss and staging, statistical significance was found only for thorax computerized tomography (CT)+18F-fluorodeoxy-glucose positron emission tomography-CT (PET-CT) use, stage and primary treatment (p<0.20). In multivariate analysis with EFS, only the primary treatment was statistically significant (p=0.001). In the group receiving non-curative treatment, the median EFS was 10.5 months while in the curative operation group it was 14.7 months. When all the primary treatment groups were taken into consideration, grade III/IV side effect swas observed in 57 patients (46.6%). Esophagitis was most prominent among those that received definitive radiotherapy. Conclusions: Independent prognostic factors among these 122 heterogeneous LA-NSCLC T4 N0-3 M0 patients were age at diagnosis, ECOG-PS, stage and primary treatment, the last also being a significant prognostic indicator of EFS. Our findings point to the importance of appropriate staging and a multidisciplinary approach with modern imaging methods in this patient group. In those with T4 lesions, treatment selection and the effective use of curative potential should be the most important goal of clinical care.

Designing female-oriented computer games: Emotional expression

  • 세림림;이원정
    • 만화애니메이션 연구
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    • 통권20호
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    • pp.75-86
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    • 2010
  • 최근 여성 게이머의 수가 급속히 증가하면서, 전자 게임 산업계에서는 아직 상당 부분 미 개척된 여성 시장을 공략할 방법을 모색하기 시작했다. 중국 인터넷 네트워크 정보 센터(CNNIC)에서 최근 발표한 게임시장 조사 보고서에 따르면, 중국 내 전체 게이머의 수는 2009년에 24.8%가 증가한 69,130,000명에 이르며, 이 중 거의 40%에 이르는 38.9%가 여성 게이머이다. 중국 상하이의 I리서치 회사에서 작성한 일련의 연구 보고서는 2003년에서 2009년 사이에 여성 게이머가 8%에서 49% 이상으로 급격히 증가하였다는 것을 보여주고 있다. 이는 과거에 게임 제작 회사들이 남성 게이머에게 얼마나 신경을 쏟았는지 그리고 여성 게이머를 얼마나 간과해왔는가와 상관없이, 게임회사들은 이제 이러한 현실에 직면해야하고, 이에 맞춰 마케팅 정책을 바꿔나가야 한다는 것을 의미한다. 본 연구에서는 첫째 비디오 게임에서의 성별에 따른 선호 요소를 분석하여, 남성 게이머들은 전자 게임을 하면서 공격, 폭력, 경쟁, 빠른 동작의 요소에 더욱 끌리는 반면, 여성 게이머들은 인물의 관계를 이해하는 게임의 정서적, 사회적 측면에 관심을 가진다는 점을 보인다. 관련문헌에서도 여성 게이머들은 익숙한 환경을 지닌 게임, 게이머들이 함께 할 수 있는 게임, 한 가지 방식 이상으로 승리할 수 있는 게임 그리고 캐릭터가 죽지 않는 게임을 선호한다는 점을 지적하고 있다. 둘째, 정서적 측면에서 본 여성 친화적 게임의 특성을 논하면서, 펫 게임(육성 게임), 드레싱 게임(옷 입히기 게임), 사회적 시뮬레이션과 같은 시뮬레이션 범주가 여성 게이머가 가장 선호하는 타입이라는 것을 제시한다. 왜냐하면 이러한 게임들은 여성 게이머에게 절대적으로 매력적인 사랑, 공유, 질투, 우월, 신비와 같은 정서를 가득 채우기 가장 적합한 게임 타입이기 때문이다. 마지막으로, 앞서 논의한 내용과 연관해서, 여성 지향적인 게임 디자인과 관련한 몇 가지 원리를 제안한다. 이는 호감 가는 외모의 주 캐릭터의 소개, '생동감 있는' NPC와 함께할 재미있는 이야기 만들기 그리고 타인 돌보기와 분류, 선별하는 여성적 특성과 관심을 만족시킬 수 있는 방법들을 포함한다.

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고립성 골 전이를 동반한 식도편평세포암에서 동시 항암화학방사선 요법 후 완전관해를 보인 1례 (A Case of Complete Remission after Concurrent Chemoradiotherapy for Esophageal Squamous cell Carcinoma with Solitary Bone Metastasis)

  • 이우진;전훈재;김예지;김선영;서민호;최혁순;김은선;금보라;진윤태;이홍식;엄순호;김창덕;류호상
    • Journal of Digestive Cancer Research
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    • 제1권1호
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    • pp.53-57
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    • 2013
  • 원격장기 전이를 동반한 식도암 환자에서 아직까지 정립 된 효과적인 치료는 없는 실정이며, 환자의 전신수행능력에 따라 전신 항암화학요법 또는 대증 요법이 시행되고 있다. 저자들은 진단 당시 고립성 골 전이를 동반한 식도암 환자에서 항암화학방사선 요법으로 완전관해를 이룬 드문 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 57세 남자가 약 2개월 전부터 시작된 진행하는 연하곤란 및 체중감소를 주소로 내원하였다. 환자는 상부 위장관 내시경 검사 및 영상의학적 검사를 통해 5번째 흉추에 고립성 전이를 동반한 식도편평세포암으로 진단되었다. 연하곤란의 완화를 위하여 2달간 항암화학방사선 요법을 계획하였으며, 원발성 식도암 병변에 대한 방사선 조사 범위에 흉추의 골전이 병변이 포함되어 원발성 병변과 함께 흉추에 대해서도 항암화학방사선 요법을 시행하였다. 동시 항암화학요법이 끝난 뒤에 4주기의 추가 항암화학요법을 시행하였다. 추적관찰 전산화 단층촬영 및 양전자방출단층촬영에서 이전에 관찰되었던 원발성 식도암, 식도주변의 림프절 병변 및 흉추의 골 전이 병변은 더 이상 관찰되지 않았으며, 추적 내시경 조직 검사상암세포는 관찰되지 않았다.

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