• Journal of Chest Surgery
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• 제23권4호
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• pp.646-653
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• 1990

Currently numerous methods are in use for myocardial protection from the ravages of ischemia and hypoxia. This study was designed to compare with FDP-GIK[Group II, n=8] and GIK cardioplegic solution[Group I, n=8] in ability of myocardial protection and was examined in the isolated working rat heart subjected to long period[120 min] of hypothermic[10 - 15K] ischemic arrest with multidose[every 30 min] cardioplegic infusion. During postischemic reperfusion period 20 min, hemodynamic functions[aortic flow, coronary flow, peak aortic pressure, cardiac output, heart rate], biochemical enzymatic & electrical activities were evaluated. The time from onset of reperfusion to the return of regular sinus rhythm was significantly reduced from 87$\pm$3 sec to 17$\pm$2 sec[P<0.05]. The postischemic recovery of aortic flow was better in the group II [95.1$\pm$3.3% of its preischemic control level] than in the Group I [75.4$\pm$6.8%] [P<0.05]. Cardiac output and stroke volume was also better in the group[91.3$\pm$1.6%, 89.4$\pm$2.6%, respectively] than in the Group I [79.1$\pm$3.7%, 77.0$\pm$4.8%, respectively] [P<0. 05]. Creatine kinase leakage was also significantly reduced from 33.8$\pm$4.9 IU /10 min / gm * dry weight to 15.4$\pm$3.6 IU /10 min /gm * dry weight[P<0.05]. It is suggested that adding FDP to GIK cardioplegic solution improves its ability to protect the heart against long period of hypoxic ischemia.

• 생물환경조절학회지
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• 제31권3호
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• pp.230-236
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• 2022

이번 연구는 효과적으로 2화방 개화묘를 생산하여 조기에 토마토를 수확하고 수확 기간을 연장하기 위하여 적절한 양액 농도 관리방법을 구명하기 위해 실시되었다. 처리는 양액 농도로 1줄기 2화방 개화묘 연구에서는 양액 EC를 1.5, 2.0, 2.5dS·m^-1, 동적 관리(3.0 → 3.5 → 4.5dS·m^-1)로 공급하였다. 육묘기간은 65일로 관행묘에 비해 20-40일, 1화방 개화묘(큐브 육묘)보다는 10일 정도 길었다. 초장은 EC 2.5dS·m^-1와 동적 관리는 각각 78, 77cm로 EC 1.5dS·m^-1처리 88cm보다 짧았다. 정식 전 큐브 내 EC는 동적 관리가 EC 5.5dS·m^-1로 가장 높았으며, EC 1.5dS·m^-1로 공급한 큐브는 3.0dS/m으로 가장 낮았다. 2화방 개화묘에서 EC 처리 간 생산량 차이는 나타나지 않았으나 1화방 개화묘는 2화방 개화묘보다 생산성이 떨어졌다. 2화방 개화묘는 첫 수확일이 6월 4일로 정식 후 35일만에 수확하였으며 1화방 개화묘는 6월 11일로 42일만에 수확하였다. 절곡에 의한 초장 및 뿌리 생육의 차이는 나타나지 않았다. 2줄기 2화방 개화묘 생산 연구에서는 공급 양액 EC를 2.0, 2.5, 3.0dS·m^-1, 동적 관리(3.0 → 3.5 → 4.5dS·m^-1)로 하여 공급하였다. 육묘 기간은 90일로 관행묘에 비해 40-50일, 1화방 2줄기 개화묘(큐브 육묘)보다는 10일 정도 길었다. 초장은 공급 양액 EC 2.0dS·m^-1에서 80cm, 2.5dS·m^-1에서는 81cm였으며 3.0dS·m^-1 처리에서는 75cm, 동적 관리에서는 73cm로 가장 짧았다. 배지 내 EC는 모든 처리에서 육묘 기간이 길어질수록 높아졌으며 특히 공급 EC가 가장 높았던 동적관리 처리에서 EC 5.1dS·m^-1로 가장 높았다. EC 처리 간 생산량 차이는 나타나지 않았으나 육묘 기간이 10일 정도 길었던 2화방 개화묘가 1화방 개화묘보다 15% 정도 생산량이 많았다. 2화방 개화묘의 초장을 짧게 만들기 위해서는 가식 후 공급 양액 농도를 높이는 방법이 가장 효율적인 방법으로 판단된다.

• The Korean Journal of Physiology
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• 제14권2호
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• pp.17-20
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• 1980

This study was undertaken to investigate the effect of the acidosis on the gastric acid secretion in the isolated whole stomach of the rat and the effect of prostaglandin $E_1$ on the gastric acid secretion influenced by the acidosis. Twenty-two male albino rats(Sprague-Dawley strain) were used. The isolated whole stomach from each rat was introduced into the Kreb's solution which was continuously gassed with $95%O_2-5%CO_2$ for 1 hour, after irrigation of the lumen with cold physiological saline$(4^{\circ}C)$. Thereafter, each stomach was irrigated again with 5% dextrose solution (pH 7.4, $37^{\circ}C$), and filled with the dextrose solution. All the stomachs with the dextrose solution were divided into 4 groups according to the Kreb's solutions in which each stomach was incubated for 30 min: 1) control group, in the pH 7.4 solution, 2) $PGE_1$ group, in the pH 7.4 solution containing $5\;{\mu}g/ml$ of $PGE_1$, 3) acid group, in the pH 7.0 solution, and 4) $acid+PGE_1$ group, in the pH 7.0 solution containing $5\;{\mu}g/ml$ of $PGE_1$. After incubatory period, the contents of each stomach were collected and centrifuged(1,500 rpm, room temperature) for 15 min. The acid output in the supernatant was determined with 0.012 N NaOH by means of autotitrator(Dosimat, Metrohm Herisau Co.) at pH 7.4. Results obtained were as follows: 1) The acid output of the acid group increased significantly in comparison with the control value. 2) The acid output of the $acid+PGE_1$ group decreased significantly in comparison with the acid group. It is inferred from the above results that the acidosis facilitates the gastric acid secretion and $PGE_1$ inhibits the gastric acid secretion induced by the acidosis.

• Asian-Australasian Journal of Animal Sciences
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• 제15권3호
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• pp.366-370
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• 2002

The objective of this study was to examine whether feeding induced hypovolemia (decrease in plasma volume) acts on the regulation of feed intake in goats fed on dry forage. In order to prevent feeding induced hypovolemia, a 2 h intravenous infusion (16-18 ml/min) of isotonic mannitol solution was begun 1 h prior to feeding and continued until 1 h after the start of the 2 h feeding period. The intravenous infusion of isotonic mannitol solution (MI) decreased plasma osmolality by 1.0%, plasma total protein concentration by 4.2% and hematocrit by 5.9%, respectively. In comparison with no infusion (NI), MI significantly decreased thirst level by approximately 13%. At the completion of the 2 h feeding period, cumulative feed intake had been increased by 43% by MI. In conclusion, feeding induced hypovolemia in goats fed on dry forage increased thirst level more than the increase in plasma osmolality did. The results demonstrate that feeding induced hypovolemia is one of the factors controlling feed intake in goats fed on dry forage.

• Nuclear Engineering and Technology
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• 제45권2호
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• pp.191-202
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• 2013

A numerical analysis of thermal stratification in the upper plenum of the MONJU fast breeder reactor was performed. Calculations were performed for a 1/6 simplified model of the MONJU reactor using the commercial code, CFX-13. To better resolve the geometrically complex upper core structure of the MONJU reactor, the porous media approach was adopted for the simulation. First, a steady state solution was obtained and the transient solutions were then obtained for the turbine trip test conducted in December 1995. The time dependent inlet conditions for the mass flow rate and temperature were provided by JAEA. Good agreement with the experimental data was observed for steady state solution. The numerical solution of the transient analysis shows the formation of thermal stratification within the upper plenum of the reactor vessel during the turbine trip test. The temporal variations of temperature were predicted accurately by the present method in the initial rapid coastdown period (~300 seconds). However, transient numerical solutions show a faster thermal mixing than that observed in the experiment after the initial coastdown period. A nearly homogenization of the temperature field in the upper plenum is predicted after about 900 seconds, which is a much shorter-term thermal stratification than the experimental data indicates. This discrepancy may be due to the shortcoming of the turbulence models available in the CFX-13 code for a natural convection flow with thermal stratification.

• 한국지하수토양환경학회:학술대회논문집
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• 한국지하수토양환경학회 2004년도 임시총회 및 추계학술발표회
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• pp.312-316
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• 2004

Single-well tracer tests, especially push pull tracer tests, are more effective to estimate hydraulic parameters and microbial metabolic activities in terms of duration and cost compared to multi-well tracer tests. However, there are some drawbacks in accuracy, complicated data analysis and uniqueness. These shortages are thought to be derived from the applied conditions which affect mass recovery curve and breakthrough curve. Factors such as extraction rate, resting period, hydraulic conductivity and hydraulic gradient are considered as the major factors determining the mass recovery rate and shape of the breakthrough curve. The results of the sensitivity analysis are summarized as follows: 1) the significant change in concentration of breakthrough curve is obtained when the extraction rate increases. This effect would also be much higher if the hydraulic conductivity is lower; 2) the mass recovery rate decreases with the increase of resting time, and the difference of mass recovery rates for different resting times is inversely proportional to the hydraulic conductivity; 3) the sensitivity values decrease with time. The hydraulic conductivity affects not only the early period, but the later period of the breakthrough curves; 4) The influence of the hydraulic gradient on the breakthrough curves is greater at earlier stage than at later stage. The mass recovery rate is inversely proportional to the hydraulic gradient.

• Journal of Oral Medicine and Pain
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• 제40권1호
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• pp.10-16
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• 2015

Purpose: Pilocarpine has the effects on improvement of salivary flow and subjective symptoms for xerostomic patients. Because of unwanted side effects following its systemic administration, topical pilocarpine has been paid attention as an alternative. This study aimed to investigate effects of pilocarpine solution as mouthwash on salivary flow and adverse effects compared to systemic administration of 5 mg pilocarpine tablet in healthy subjects. Methods: The study was a double blind, placebo-controlled, crossover clinical trial. Five milligrams pilocarpine tablets, 4 mL of 2% pilocarpine solution and placebo solution were given to 12 healthy volunteers (6 males and 6 females) in a predetermined order with wash-out period of at least two days and unstimulated whole saliva was collected before and after administration of each drug. Blood pressure and pulse rate was also measured and subjective effect and potential side effects were evaluated by a self-administrated questionnaire. Results: Systemic (5 mg tablet) and topical (2% solution) use of pilocarpine significantly increased salivary flow rate in healthy subjects compared to placebo (p<0.001). In both the pilocarpine solution and tablet groups, salivary flow rates at 120 minutes after administration remained increased. Subjective effect on salivation was the largest in the pilocarpine tablet group, followed by the pilocarpine solution group (p<0.05). There was no significant difference in blood pressure and pulse rate after administration of all three drugs. Fewer side effects reported in the pilocarpine solution group than in the tablet group. Conclusions: Two percents pilocarpine solution as mouthwash increases salivary flow rate, definitely superior to placebo solution and comparable to pilocarpine tablet, with fewer side effects in healthy subjects. It indicates a possibility of pilocarpine solution as a useful alternative of pilocarpine tablets for the xerostomic patients with systemic diseases.

• 한국세라믹학회지
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• 제24권1호
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• pp.77-85
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• 1987

Hardened cement paste is mainly affected by corrosion of sulphate and chlorine ions in sea water. In this investigation, many specimens were made with the cement clinker minerals such as C3S, C3A, C4AF and their mixture according to cement composition added various blending materials. After the specimens were immersed in 4% MgSO4 and MgCl2 solutions, the product of reaction, the microstructure of specimen and Ca+2 ion leached in the solution were studied. The formation of Ca(OH)2 in the specimen of C3S is reduced relatively by adding pozzolanic admixtures. The chlorine ion is easily diffuse into the C3S specimen and produced CaCl2 compound, and it makes the specimen porous by leaching out itself into the solution. The specimen of C3A, C4AF are broken down by expanding reaction of ettringite and gypsum compound produced in the MgSO4 solution. At a later period, the ettringite is transformed into gypsum and 5MgO.2Al2O3·15H2O. The C3A in the MgCl2 solution combines chlorine ion to form Friedel's salt and prevents the diffusion reaction of chlorine ion into the specimen. Granulated slag shows inferior effect on the resistance of the specimen in MgSO4 solution by forming ettringite and gypsum, but good result in MgCl2 solution. Pozzolanic materials, on the whole, offer noticable effect on the resistance of the specimen in both solutions.

• 생물환경조절학회지
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• 제6권1호
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• pp.1-14
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• 1997

환경 보전에 대한 필요성이 대두되면서 비순환식 양액재배 시스템이 순환식 양액재배 시스템으로 전환됨에 따라 순환식 양액재배 시스템에 적합한 배양액의 개발이 시급히 요구되고 있다. 따라서, 순환식 고형배지경에 적합한 배양액을 개발하기 위하여 본 실험을 수행하였으며 그 결과는 다음과 같다. 1. 오이 순환식 고형배지경에 적합한 배양액 조성 및 농도를 알아보기 위하여 일본 야채 시험장 표준액을 1/2 배액, 1 배액 및 3/2 배액으로 조제하여 오이를 재배한 결과, 오이의 초장은 배양액농도를 높임에 따라 짧아졌으며 엽장, 엽폭 및 처리 농도간에 차이가 없었고 상품과수와 상품수량은 1 배액에서 가장 많았다. 양수분흡수율(n/w)에 따라 개발된 오이 순환식 고형배지경에 적합한 배양액 조성(SCU 배양액)은 영양 생장기 동안 N 11.4, P 3.3, K 6.0, Ca 4.5 및 Mg 3.5 me.$\ell$$^{-1}$, 생식 생장기 동안 N 10.4, P 3.3, K 5.0, Ca 4.5 및 Mg 3.5 me.$\ell$$^{-1}$이었다. 2. 순환식 배양액으로 개발된 SCU 배양액의 적합성을 검정하기 위하여 산기 배양액, PTG 배양액 및 SCU 배양액에서 오이를 재배한 결과, 근권내 EC와 pH는 모든 배양액에서 생육기간 동안 안정적이었다. 배양액 내의 다량원소를 측정한 결과, 산기 1 배액, PTG 1 배액, SCU 1/2 배액, SCU 1 배액 및 SCU 3/2 배액 모두 오이의 생육이 진전됨에 따라 배양액내 N, P 및 K 농도는 감소하였으며 Ca 농도는 완만하게 상승하였다. Mg는 뚜렷한 경향을 보이지 않았다. 오이의 광합성속도는 SCU 1 배액, SCU 3/2 배액 및 산기 1 배액에서 높았다. 생육은 SCU 1/2 배액에서 가장 낮았고 SCU 1 배액과 SCU 3/2 배액, 산기 1 배액 및 PTG 1 배액에서는 처리간에 차이를 보이지 않았다. 엽내 N, P, K 및 Mg 함량은 SCU 1 배액, 산기 1 배액 및 PTG 1 배액에서 적정 수준을 나타냈고 엽내 Ca 함량은 PTG 1 배액에서 낮았다. 총수량은 SCU 1 배액에서 가장 높았고 다음으로 산기 1 배액에서 높았다. 따라서 본 실험에서 개발된 배양액(SCU 배양액)은 오이 순환식 고형배지경에 적합한 배양액이라 할 수 있다.

• 한국자원식물학회지
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• 제18권3호
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• pp.417-423
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• 2005

쪽 생즙액의 염색조건에 따른 견직물의 염색성을 조사하기 위해 염액온도, 염색시간, 염액농도 염액의 pH, 매염제를 달리하여 견직물을 염색하였다. 염액의 온도에 따른 견직물의 표면색은 온도가 낮을수록 b값이 작아져 $-5^{\circ}C$와 상온에서는 녹색(G) 계열로, $40^{\circ}C$ 이상에서는 녹황색(GY) 계열로 발색되었으며, 염착농도는 온도가 높을수록 높았다. 염색시간은 표면색에 영향을 미치지 않았으나 염색시간이 길수록 염착농도는 증가하였다. 염액농도를 $1\%,\;2\%,\;3\%,\;4\%$로 조정하여 견직물을 염색했을 때는 청록색(BG) 계열로 발색되었으나 $5\%$에서는 B계열로 발색되었고, 염착농도는 염액의 농도가 높을수록 증가하였다. 염액의 pH에 따른 견직물의 표면색은 pH 7이하에서는 G계열을, pH 8에서는 녹황색(GY)으로, pH 9에서는 황적색(YR) 계열을 나타냈다. 염착농도는 pH가 높을수록 낮아졌다. 매염처리는 견직물의 표면색에 영향을 미쳤으며, 염착농도도 증가시켰다.