• Title/Summary/Keyword: period of the disease

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A Study on the Oegamsibeong(外感時病) Theory in "Sibeongron(時病論)" ("시병론(時病論)"의 외감시병이론(外感時病理論)에 대한 고찰)

  • Eun, Seok-Min
    • Journal of Korean Medical classics
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    • v.22 no.1
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    • pp.111-120
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    • 2009
  • "Sibeongron(時病論)" is a book that was written by Noepung(雷豐, Leifeng) in the latter period of Cheong(淸) dynasty. In this book, Noepung described the Siryeong(時令) disease by oegam(外感), and the theoretical tool he used to analyze the Siryeong disease was the Ungi(運氣) theory based on "Naegyeong(內經)". Based on the Ungi theory, Noepung(雷豐) classified the Siryeong(時令) disease into two groups of singam(新感) and bokgi(伏氣), so that his theory of Siryeong disease could successfully describe the Siryeong diseases of four seasons. To understand his theory of Siryeong disease, it is very important to understand the concept of the relation between the division of time and the etiological cause by oegam(外感). Based on this concept, this study will be analyzing how each Siryeong disease was defined in his etilogical view which had been originated from the Ungi(運氣) theory in "Naegyeong".

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A Study on Cold Damage(傷寒) in the Compendium of Prescription from the Countryside(鄕藥集成方) - Focusing on citation, medical theory, prescription, medicinal herbs - (조선 의서 『향약집성방』 중에 실린 상한(傷寒) 논의 연구 - 인용 문헌, 의론(醫論), 처방, 본초 등을 중심으로 -)

  • Oh, Chae-Kun
    • The Journal of Korean Medical History
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    • v.25 no.2
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    • pp.121-136
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    • 2012
  • The purpose of this paper is to derive the features of cold damage clinical medicine during the early days of the Chosun(朝鮮) period by analyzing discussions on cold damage published in the official medical book of the Chosun period, Compendium of Prescription from the Countryside(鄕藥集成方, CPC). Cold damage was one of the typical diseases in East Asia where there was constant seeking of the utilization of prescriptions, ways of preparations, and awareness regarding cold damage as shown in Zhang, Zhongjing(張仲景)'s Treatise on Cold Damage Disease(傷寒論, TCDD) below. Traditional Korean medicine which possessed the medical universality of East Asia also was no exception and through an analysis of the part on cold damage in CPC, it is expected that medical features of cold damage in Korea passed down from the Koryo(高麗) Dynasty to the early Chosun period will be revealed. For this, first there needs to be an organization of past discussions on cold damage surrounding the existence of infection and after checking the issues, exploring which of the writings related to TCDD and editions are being utilized through an analysis on citing literature of Cold Damage Disease Literature(傷寒門) and Heat Pathogen Disease Literature(熱病門) which have developed discussions on cold damage in CPC. In addition, by comparing Peaceful Holy Benevolent Prescription(太平聖惠方, PHBP) and Complete Record of Sacred Benevolence(聖濟總錄, CRSB), known to have greatly influenced CPC and Cold Damage Literature and Heat Pathogen Disease Literature, features of form and content used by CPC were analyzed. Features of form were examined through pattern of organization and number of citing literature were examined and for features of content, cold damage infection, classification, syndrome differentiation method, and utilization of materia medica among prescriptions were examined. Discussions on cold damage as being uninfectious as stated in Treatise on the Pathogenesis and Manifestations of All Diseases(諸病源候論) unlike pestilence, epidemic pathogen(時氣), warm pathogen disease(溫病), and heat pathogen disease were excluded in PHBP. PHBP opened the possibility of cold damage infection and later writings, CRSB and CPC also follow this. As a result of analyzing citing literature of the part on cold damage in CPC, it is uncertain which edition of TCDD is being utilized; however, the most distinctive feature was that Classified Emergency Materia Medica(證類本草) and not writings specializing in cold damage are in use. In general, although CPC in terms of form is similar to CRSB, content creation predominantly depended on PHBP. More specifically; first, in terms of the existence of cold damage infection, arguments of PHBP and CRSB are maintained. Second, in terms of cold damage classification, although CRSB is followed, heat pathogen disease is classified separately developing PHBP as is. Third, in terms of method, as Book of Keep Healthy(南陽活人書) and CRSB compiled in later times are cited, it is deemed that arguments were raised to a certain extent regarding six-meridian syndrome differentiation(六經辨證). Fourth, although the majority of utilized materia medica among cold damage prescriptions utilize Materia Medica from the Countryside(鄕藥本草) in CPC and materia medica from Korean Peninsula, this is due to the desire for the compilation performance of CPC to be propagated to ordinary citizens and not the ruling class. CPC as the official medical book compiled in the early days of the Chosun period was greatly influenced by the Song(宋) Dynasty's medical books, PHBP and CRSB shows that cold damage medicine in the early Chosun Period indeed possesses the medical universality of East Asia. Furthermore, the features of published medical theory and prescriptions reveal the existence of the cold damage medical tradition of the Chosun period serving as clues for cold damage research tradition among Korea's medical history.

The Role of Enzyme Replacement Therapy in Fabry Disease in Cardiology Perspective

  • Hongo, Kenichi
    • Journal of mucopolysaccharidosis and rare diseases
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    • v.4 no.1
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    • pp.21-25
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    • 2018
  • Fabry disease is a hereditary lysosomal storage disorder caused by the reduction or absence of lysosomal enzyme alpha-galactosidase A and the accumulation of glycosphingolipids, such as globotriaosylceramide (Gb3), in various organs, including the heart. The prevention of cardiac involvement in Fabry disease can only be achieved by enzyme replacement therapy (ERT), and the method of assessing the efficacy of ERT should be confirmed. Changes in the electrocardiogram, such as the shortening of PQ interval, prolongation of QTc and repolarization abnormalities as well as left ventricular hypertrophy in voltage criteria, can be used to identify Fabry disease patients; however, the usefulness of electrocardiograms for evaluating the efficacy of ERT is limited. The assessment of left ventricular hypertrophy using echocardiography has been established to evaluate the efficacy of ERT during long-term period. A new technique involving speckled tracking method might be useful for detecting early cardiac dysfunction and identifying the effect of ERT for a relatively short period. The estimation of left ventricular hypertrophy using cardiac magnetic resonance (CMR) is also useful for assessing the efficacy of ERT. Identifying late gadolinium enhancement in CMR may affect the effectiveness of ERT, and the new technique of T1 mapping might be useful for monitoring the accumulation of Gb3 during ERT. Histopathology in cardiac biopsy specimens is another potentially useful method for identifying the accumulation of GB3; however, the use of histopathology to evaluate of the efficacy of ERT is limited because of the invasive nature of an endomyocardial biopsy.

Review of Case Reports of Neuropsychiatry Disease in Oriental Medicine (한의학에서 신경정신과 질환의 증례논문 동향분석)

  • Heo, Eun-Jung;Han, Chang-Hyun;Kim, Wu-Young;Park, Sang-Young;Jeon, Won-Kyung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.25 no.4
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    • pp.708-714
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    • 2011
  • This study was aimed to review the trend of case reports of neuropsychiatry disease. The case reports were collected by retrieving Journal of Oriental Neuropsychiatry and analyzing period were from 1990 to 2010. We analyzed them for publish year, research institution, patients, sorts of diseases, pattern identification diagnosis, instrument, treatment period, sorts of treatments, and treatment with western medicine. We analyzed 142 case reports and there were many kinds of neuropsychiatry diseases and instruments that were evaluated the process. The reserchers used various treatment with oriental medicine. However, the number of case reports have decreased since the year of 2008. Most of the research institutions were university and general oriental medical hospital and the portion of private hospitals was only 2.11%. For the development of practical clinical trial of oriental medicine, we needs more qualifying case report. We hope more reserchers for psychiatry disease of oriental medicine will be interested in the publication of case report and this will serve to produce advance of oriental medicine.

Monitoring of Major Viral Pathogen Contamination in New and Reused Broiler Farm Litter (육계 농장 깔짚에서의 주요 바이러스 병원체 오염 실태 조사)

  • Choi, Kang-Seuk;Jeon, Woo-Jin;Lee, Eun-Kyoung;Kwon, Jun-Hun;Lee, Jin-Hwa;Sung, Haan-Woo
    • Korean Journal of Poultry Science
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    • v.38 no.3
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    • pp.181-189
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    • 2011
  • A 5-month (May to November in 2009) monitoring program for five viral pathogens in litter, such as avian influenza virus A (AIV), infectious bronchitis virus (IBV), infectious bursal disease virus (IBDV), fowl adenovirus (FAdV), and chicken infectious anemia virus (CIAV) was conducted in 62 flocks at 31 broiler farms (two flocks in each farm) in Korea in 2009. Viral pathogens were examined twice (before and at the end of the rearing period) at 31 broiler farms, and included fresh litter (n = 16) and recycled litter (n = 15) farms. Thirty-seven viruses (14 IBVs, 2 IBDVs, 9 FAdVs, and 12 CIAVs) were isolated from 75% (12/16) and 73% (11/15) of fresh litter and reused litter farms during the period, respectively, indicating no difference in viral contamination rate between farms using new and reused litter. Of these isolates, three (two CIAVs and one IBDV) were isolated from recycled litter samples collected before the rearing period at three broiler farms, whereas the others (n=34) were isolated from fresh and recycled litter samples collected at the end of the rearing period. When the performances, involving viability, body weight, and feed conversion ratio, were compared, no significant differences were found between farms using fresh and recycled litter during the period.

Cultivar Resistance of Korean Breeding Cut-Rose against Crown Gall by Agrobacterium tumefaciens Evaluated by an In Vitro Inoculation

  • Serah Lim;Se Chul Chun;Jin-Won Kim
    • The Plant Pathology Journal
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    • v.39 no.2
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    • pp.220-227
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    • 2023
  • Rose crown gall caused by Agrobacterium tumefaciens is a major disease that damages the production of cutroses in Korea. The effective prevention methods for this disease include the use of resistant varieties. This study was conducted to evaluate the resistance of 58 Korean cultivars and six foreign cultivars to crown gall disease with nodal explants in vitro. Among 180 A. tumefaciens strains, pathogenic strain RC12 was selected as an inoculant strain. The strain RC12 was identified based on characteristics of some selective media, pathogenicity test, and polymerase chain reaction analysis. Forty rose cultivars formed tumors on explants inoculated with A. tumefaciens RC12. However, 24 cultivars, including 22 Korean cultivars and 2 foreign cultivars, showed resistance to A. tumefaciens RC12 without forming any tumors. Six cultivars with tumor formation rates of over 30% formed initial tumors within 23 days after inoculation. Six cultivars with low tumor formation rates of around 5% formed initial tumors after 28 days of inoculation. It was found that gall formation rate was highly correlated with the initial gall formation period. Thus, the relationship between the period of gall formation and the rate of gall formation could be useful for assessing resistance to crown gall disease. In vitro inoculation methods could be used to evaluate resistance of cut-rose cultivars to crown gall diseases.

Clinical Study for the One Case that Diagnosed Polycystic Ovarian Disease (다낭성 난소증후군 치험 1례)

  • Kim, Ji-Ye;Jung, So-Young
    • The Journal of Korean Obstetrics and Gynecology
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    • v.27 no.3
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    • pp.151-157
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    • 2014
  • Objectives: The aim of this study is to report the effect of oriental treatments for polycystic ovarian disease patient with amenorrhoea. Methods: A 27 years old women, who diagnosed polycystic ovarian disease, was enrolled in this study. She received oriental treatment such as herbal medicine, acupuncture for 8 months. And we proceeded to checkup female hormone regularly, such as Estrogen, LH, FSH, Prolactin. We observed the menstruation period and figure out LH/FSH ratio. Results: Polycystic ovarian disease patient restart cyclic menstruation. LH/FSH ratio of polycystic ovarian disease patient was decreased to normal level. Conclusions: In polycystic ovarian disease patient with amenorrhoea in this case, oriental herbal medicine and acupuncture treatment make cyclic menstruation and restore LH/FSH ratio to normal level.

A Review of Clinical Studies of Integrated Traditional Chinese and Western Medicine Therapy for Legg-Calve-Perthes Disease Using China National Knowledge Infrastructure Database: Focused on Clinical Studies after 2000 (대퇴골두의 연소성 골연골증의 중·서양 협진치료에 대한 임상 연구 동향: 2000년 이후 발표된 연구를 중심으로)

  • Choi, Yun-Young;Yang, Su-Hyun;Park, Jae-Eun;Oh, Seung-Ju
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.3
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    • pp.57-72
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    • 2021
  • Objectives This study was conducted to investigate clinical studies about Integrated Traditional Chinese and Western Medicine therapy for Legg-Calve-Perthes disease. Methods We searched clinical studies about Integrated Traditional Chinese and Western Medicine therapy for Legg-Calve-Perthes disease through China National Knowledge Infrastructure. 17 articles published from 2000-2021 were finally chosen and analyzed by published year, study design, number of samples, diagnosis criteria, evaluation criteria, treatment period, follow up period, treatment method. Results Herbal medicine, external treatment, Chuna massage therapy were performed for traditional Chinese medical treatment. For Western medicine treatment, conservative treatment and surgical treatment were performed. Above them, herbal medicine and conservative treatment were mostly used for treating Legg-Calve-Perthes disease. Conclusions By analyzing clinical studies, We found that Integrated Traditional Chinese and Western Medicine therapy can be helpful for treating Legg-Calve-Perthes disease. In Korea, more clinical research about Legg-Calve-Perthes disease is still needed. This study will be helpful for future research on Korean medicine for Legg-Calve-Perthes disease.

A Case of a Patient with Dizziness Diagnosed with Guorem-byeong Baekho-tang (궐음병(厥陰病) 백호탕(白虎湯)으로 진단된 어지럼증 환자 1례)

  • Choi, Woon-yong
    • 대한상한금궤의학회지
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    • v.10 no.1
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    • pp.143-152
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    • 2018
  • Objective : A Patient complaining of dizziness was diagnosed and treated with the Shanghanlun disease pattern identification diagnostic system and was analyzed to report cases Methods : Based on the Shanghanlun disease pattern identification diagnostic system, we analyzed a case treated with the Baekho-tang and counseling. Results : Baekho-tang showed a rapid improvement in the patient. During the period of 20 days, dizziness were greatly improved. Conclusions : The Baekho-tang, which is not well known yet, can show rapid effect and can be diagnosed frequently through the Shanghanlun disease pattern identification diagnostic system.

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