• 한방비만학회지
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• 제8권2호
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• pp.25-35
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• 2008

Objectives This study was performed to find out the characters about distribution of abdominal fat(especially superficial and deep subcutaneous fat) in obese premenopausal Korean women. Methods 39 obese premenopausal women were recruited in 2008. Anthropometry and body impedance analysis have been done and abdominal fat distribution had been assessed by computed tomography scan at the level of L4-5. Blood test and questionnaires about depression, eating attitude and physical activity were underwent. Result Abdominal total fat area, subcutaneous fat area including superficial and deep were significantly correlated with anthropometry and BIA result while visceral fat was correlated only with age and waist circumference. In blood profile, only visceral fat area was correlated with HDL cholesterol and triglyceride. And there were no correlation among questionnaires and abdominal fat. There were no difference between superficial and deep subcutaneous fat. Conclusion Abdominal subcutaneous fat including superficial and deep did not have any correlation with heart risk factor. superficial and deep subcutaneous fat had no differences with each other and they did not show any correlation with visceral fat in obese perimenopausal Korean women.

• 여성건강간호학회지
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• 제7권4호
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• pp.486-498
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• 2001

The purpose of this study was to identify transition conditions, health behavior and indicators of healthy transitions among middle-aged women based on Schumacher & Meleis(1994) transition model for developing intervention program for their health promotion. A convenience sample of 221 women aged 40-60 was obtained in Jung-Gu, Seoul and they were asked to complete the questionnaires, which consisted of modified health-promoting lifestyle profile(HPLP), knowledge of menopause, physical well-being, emotional well-being, modified women's role integration protocol (WRIP), Beck's Depression Inventory(BDI), and indicators of healthy transition with subcategories such as subjective well-being, role mastery and well-being of interrelationship. The results were as follows: 1. Women had a mean age of 47.53 years. More than half(53.39%) of the women had jobs and 88.69 % had their spouses, Of 221 women, 51.13 % were premenopausal, 19.91% were perimenopausal, and 28.96% were postmenopausal. 2. Women scored lower on health responsibility and exercise than on self actualization, nutrition and interpersonal support among subcategories of health behavior measured the modified HPLP. Only 11.98% of respondents had breast-self examination and 42.66% had pap smear for screening cancer. 3. In transition conditions, women had poor knowledge about menopause and median level of physical well-being, emotional well-being and stress. 15.45% of the women had clinical depression. 4. As for the outcome index of the transition model, the mean of indicators of healthy transition was 3.69(possible range 1-5). 5. The levels of education and economic and the menstrual status were significantly related to physical well-being, depression and stress in the categories of transition conditions. The total score of health behavior correlated negatively with depression. The total score of indicators of healthy transition correlated with physical well-being, emotional well-being, stress, and depression in the categories of transition conditions. In conclusion, these findings suggested a profile of fragile middle-aged women and contributed to developing the community-based intervention program for health promotion.

• 대한한방부인과학회지
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• 제22권3호
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• pp.197-204
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• 2009

Purpose: Obesity is the major risk factor of the heart disease and the metabolic disease. And many obese women have dysfunction of the endocrine system. There are many reports about oriental obesity treatment program. In clinics, the electroacupuncture with exercise is believed more effective. But the difference of weight loss as exercise and women was not studied. Methods: The subjects were 75 young women who visited Kangnam Kyunghee hospital for obesity management from March 2006 to July 2008. Six treatments had performed, the weight loss checked at every treatment. 52 women treated by oriental obesity treatment with exercise, 23 women treated therapy without exercise. As the exercise and the age, the weight loss was compared. Results: The weight loss of electroacupuncture with exercise was higher than that of electroacupuncture without exercise, but was not significant. The weight loss of perimenopausal women was significantly low. Conclusion: The comparison of electroacupuncture with exercise and electroacupuncture without exercise was not significantly different. The weight loss of the older women would be less than the weight loss of the younger.

• 여성건강간호학회지
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• 제3권1호
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• pp.82-92
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• 1997

The purpose of this study was attempted to understand the substance and meaning of menopause experienced by women through informal interviews with oral consent. The informants were 6 perimenopausal women of 50-55 years old who are executing menopause. Colaizz's analytical method, a type of phenomenological analysis, was used to analyze data recorded by audiotape. One professor and a master's degree student who understand phenomenology, and the one who has a master of arts examined the validity between the meanings composed of the clusters of themes. Findings were turned out to be valid through validation process as the last step. The meaning of menopause implied both 'concept about menopause' and 'menopause as a time of change'. Menopause was mostly considered as cessation of menstruation as a physiological, natural, and normal process by aging. However, some people regarded menopause as a loss of youth and womanhood and lessening of every function of the body. Menopause as the time of changes means 'the period of' 'hormonal changes' such as change of menstruation, hot flushes, perspiration, and palpitation ; 'body function changes' of visual acuity, physical strength, sleeping, digestion, thoughts, bone and joints, skin sensibility, sexual pattern and intelligence ; 'emotional changes' such as anxiety, loneliness, gloominess, and nervousness. Menopause is a turning point on the women's life cycle accompanying various kind of changes and health problems. Therefore it is inevitable to develop strategy helping menopausal women pass through the critical successfully by adapting and coping with their critical period toward the healthy and better quality of life individually rather than putting them all into the standardized hormonal replacement protocol.

• 척추신경추나의학회지
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• 제2권2호
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• pp.105-116
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• 2007

Objectives : Physical activity is known as beneficial to mental health like decreasing depression and stress. In this study, we tried to find out the relationship between body composition, stress, depression, and self-esteem with physical activity level. Methods : International Physical Activity Questionnaire(IPAQ)-short form, SRRS(Social readjustment rating scale), SRI(Stress response index), and BDI(Beck's depression index), SES(Self-esteem scale) were given to peri-menopausal women aged 45-55 and BMI$\geq$23kg/m2. They were given written consent and this study is performed under the permission of institutional review board of Kyung Hee East-west Neo Medical Center. Results : The mean of physical activity of total subjects was 2406MET-min/week(n=42). The physical activity of overweight(23kg/m2$\leq$BMI<25kg/m2) and obese(BMI$\geq$25kg/m2) permimenopausal women was 1428MET-min/week and 2970MET-min/week(p<0.05) respectively. When three levels of physical activity pattern(inactive, minimally active, and HEPA(Health-enhancing physical activity) active) was analyzed, all of them were heavily relied on the activity intensities of walking. The scores of BDI, SRRS, and SRI were lower and that of SES were higher in HEPA active group, not showing statical significance. Anger(subscale of SRI) measures were lower and SES measures were higher in HEPA active group than others among overweight women(p<0.05). Conclusions : The level of physical activity of peri-menopausal women was on the average, but the vigorous activity is thought to be necessary. The HEPA active group showed lower depression, stress and higher self-esteem than minimally active and inactive group.

• Journal of Ginseng Research
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• 제34권3호
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• pp.183-191
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• 2010

Dry mouth is easily neglected if not associated with oral diseases. Consequently, xerostomatic patients often use unconventional therapies. In traditional Korean medicine, Korean red ginseng (KRG) has long been used to relieve dry mouth. However, no clinical trials have investigated whether KRG actually has an effect on dry mouth. This study was performed to evaluate the efficacy of KRG for dry mouth. We enrolled 100 volunteers with no obvious oral or salivary gland diseases and divided them into KRG and placebo groups. Each group was divided into six subgroups according to age and gender. The subjects received 6 g/day of KRG or placebo for 8 weeks. The dry mouth visual analog scale (VAS), salivary flow rate, and a dry mouth-related symptom questionnaire were evaluated at baseline and at 4 and 8 weeks. KRG treatment did not show any significant differences for any of the variables. However, KRG improved the dry mouth VAS at 4 weeks and dry mouthrelated symptoms at 8 weeks in women, but not in men. Subgroup analyses revealed that KRG markedly improved the dry mouth VAS in women of menopausal age (40 to 59 years) at 4 and 8 weeks. KRG may have beneficial effects for dry mouth in women, especially those of menopausal age, but not in men. Further investigation in post- and perimenopausal women is required to elaborate on these findings.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2179-2184
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• 2012

Introduction and aim: To compare reproductive factor influence on patients with pathological diagnosed malignant and benign tumor in the Breast Department, The First Peoples' Hospital of Kunming in Yunnan province, China. Methods: A hospital-based case-control study was conducted on 263 breast cancer (BC) cases and 457 non-breast cancer controls from 2009 to 2011. The cases and controls information on demographics, medical history, and reproductive characteristics variables were collected using a self-administered questionnaire and routine medical records. Histology of breast cancer tissue and benign breast lesion were documented by pathology reports. Since some variables in data analysis had zero count in at least one category, binomial-response GLM using the bias-reduction method was applied to estimate OR's and their 95% confidence intervals (95% CI). To adjust for age and menopause status, a compound variable comprising age and menopausal status was retained in the statistical models. Results: multivariate model analysis revealed significant independent positive associations of BC with short menstrual cycle, old age at first live birth, never breastfeeding, history of oral contraception experience, increased number of abortion, postmenopausal status, and nulliparity. Categorised by age and menopausal status, perimenopausal women had about 3-fold and postmenopausal women had more than 5-fold increased risk of BC compared to premenopausal women. Discussion and Conclusion: This study has confirmed the significant association of BC and estrogen related risk factors of breast cancer including longer menstrual cycle, older age of first live birth, never breastfeeding, nulliparity, and number of abortions more than one. The findings suggest that female hormonal factors, especially the trend of menopause status play a significant role in the development of BC in Yunnan women.

• 대한간호학회지
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• 제50권3호
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• pp.487-500
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• 2020

Purpose: This study aimed to evaluate the validity and reliability of the Korean version of Menopause-Specific Quality of Life (MENQOL). Methods: The MENQOL was translated into Korean according to algorithm of linguistic validation process. A total of 308 menopausal women were recruited and assessed using the Korean version of MENQOL (MENQOL-K), the World Health Organization Quality of Life Brief Version (WHOQOL-BREF), and Center for Epidemiological Studies Depression Scale (CES-D-K). In estimating reliability, internal consistency reliability coefficients were calculated. Validity was evaluated through criterion validity and construct validity with confirmatory factor analyses using SPSS 23.0 and AMOS 25.0 software. Results: In item analyses, the "increased facial hair" symptom was excluded because of the low contribution of MENQOL-K. The confirmatory factor analysis supported good fit and reliable scores for MENQOL-K model, and the four-factor structure was validated (χ²=553.28, p<.001, NC=1.84, RMSEA=.05, AGIF=.85, AIC=765.28). The MENQOL-K consists of 28 items in 4 domains, including vasomotor (3 items), psychosocial (7 items), physical (15 items), and sexual subscales (3 items). There was an acceptable criterion validity with moderately significant correlation between MENQOL-K and WHOQOL-BREF. The Cronbach's α for the 4 subsacles ranged from .80 to .93. Conclusion: The MENQOL-K is a valid and reliable scale to measure condition-specific quality of life for perimenopausal and postmenopausal women. It can be used to assess the impact of menopausal symptoms on the quality of life of Korean women in clinical trials.

• 대한한방부인과학회지
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• 제24권4호
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• pp.95-104
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• 2011

Objectives: The purpose of this study is to investigate the relationship between the degree of menopausal symptom and granulocyte/lymphocyte ratio, and heart rate varibility(HRV). Methods: From 11th April 2011 to 20th May 2011, a total 30 female subjects (age 41-60) was recruited. We evaluated the degree of menopausal symptoms by Kupperman' s index and measured subject's WBC differential count and HRV. The data were analyzed by Kruskal-Wallis test and Spearman correlation test using SPSS/PC ver 13.0 program. Results: 1. There was no statistically significant difference in granulocyte/lymphocyte ratio and HRV among 4 classified groups according to Kupperman's index.- Mild, Moderate, Severe and Urgent. 2. Granulocyte ratio and general symptom score(within Kupperman's index) significantly showed negative correlation coefficient(r=-0.499, p=0.005), and Lymphocyte ratio and general symptom score significantly showed positive correlation coefficient (r=0.374, p=0.042). 3. Granulocyte/lymphocyte ratio and HRV showed no significant correlation. Conclusions: There was no significant relation among the degree of menopausal symptoms and granulocyte/lymphocyte ratio, and HRV. But furthermore large scale study is required.

• 대한한방부인과학회지
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• 제30권4호
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• pp.175-202
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• 2017

Objectives: This study was conducted towards developing a screening tool for syndrome differentiation in the diagnosis of menopause in menopausal and perimenopausal women. Methods: We conducted a literature review of studies on menopausal diagnosis based on syndrome differentiation, and examined well-founded differentiated syndromes and their respective clinical symptoms. Based on the findings, we created a questionnaire through consultations with Oriental medicine experts in physiology, pathology, and diagnostics. Finally, the research team conducted an expert Delphi study on differentiated syndromes and the associated clinical symptoms. Results: Seven differentiated syndromes were selected, including Liver Depression (肝鬱), Kidney Yin Deficiency (腎陰虛), Kidney Yang Deficiency (腎陽虛), Liver and Kidney Yin Deficiency (肝腎陰虛), Kidney Yin and Yang Deficiency (腎陰陽兩虛), Heart-Kidney Noninteraction (心腎不交), and Dual Deficiency of Heart and Spleen (心脾兩虛); 4 disease locations, including liver (肝), heart (心), spleen (脾), and kidney (腎); and 3 disease natures, including Yin Deficiency (陰虛), Qi Stagnation (氣滯), and Blood Deficiency (血虛). In addition, we added 3 supplemental disease natures, including Yang Deficiency (陽虛), Qi Deficiency (氣虛), and Heat (火熱), in consideration of syndrome differentiation categories that may possibly be added in a follow-up clinical questionnaire. Conclusions: This resulted in a total of 7 differentiated syndromes, 4 disease locations, and 6 disease natures. We translated the clinical symptoms of these 17 categories into Korean Hangeul. After consulting with 5 Oriental medicine experts and a psychology expert, we produced a questionnaire for use in diagnosing menopause based on syndrome differentiation. The calculation of scores for the syndrome differentiation screening tool will be confirmed through clinical research based on the results of a review of existing literature.