• 한국임상수의학회지
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• 제21권2호
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• pp.187-190
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• 2004

A mixed case of multiple sebaceous gland adenoma and perianal gland adenoma was found in a 11-year-old male Shih Tzu dog. Grossly, many masses less than 1 cm in diameter of back skin and single red-brown mass about 0.5 cm in diameter of inner ear were noted. In addition one of light-pink mass 5 cm in diameter was presented in the anus. All of the masses were well demarcated and dome-shaped or papillated nodules. Histologically, the mass from back and ear were composed with multiple irregular shaped or sized lobules of sebaceous glands. Masses were containing mostly mature sebaceous cells and multifocal cystic degeneration with acellular and bright eosinophilic materials. And the mass from peri-anal area was well-circumscribed and composed of broad, anastomosing trabeculae of well-differentiated hepatoid cells. There were very low mitotic figures in all masses. Based on these results, this case was diagnosed as the multiple sebaceous gland adenoma and perianal gland adenoma.

• 한국임상수의학회지
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• 제20권4호
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• pp.474-477
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• 2003

This study comprised 13 cases having canine perianal adenoma at Veterinary Medical T~aching Hospital, Seoul National University from January 2000 to October 2003. All referred dogs were intact male and mean age of dogs was 11.5 years (ranged from 7 to 15 years). The most prevalent breed was Shih Tzu. The clinical signs were presence of 1 to 5 cm in diameter firm mass, perianal swelling, hemorrhage, pain and dyschezia. The masses were located either in the perineum (12 cases) or tail (5 cases). Five dogs had masses with ulceration. Concurrent prostatomegaly and seminoma was found in 5 and 1, respectively. Castration was performed in 5 cases. In 8 cases, surgical excision of the tumor was performed with castration. There was no recurrence in all cases after removal. In all cases with castration, perianal adenomas were regressed within 1-2 months. In one case among them, excision of the tumor was also performed because of persistent ulceration. According to these clinical results, perianal adenoma excellently responded to castration with or without surgical excision of the tumor.

• 한국임상수의학회지
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• 제36권6호
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• pp.349-352
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• 2019

A five-year-old female Yorkshire Terrier dog presented with a perianal mass. Fine needle aspiration revealed that the mass comprised two different types of cells: hepatoid epithelial cells and melanin-containing melanocytes. Histopathological examination confirmed perianal gland adenoma with malignant melanoma. Evidence of metastasis was found on thoracic radiography with soft-tissue densities observed within the pulmonary parenchyma. The dog survived for three months after diagnosis of malignant melanoma. This report describes the clinical findings, diagnostics used, cytological and histopathological findings, and the potential prognosis for a dog diagnosed with malignant anal sac melanoma.

• 한국임상수의학회지
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• 제32권1호
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• pp.120-122
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• 2015

Hepatoid gland tumors in dogs usually occur in the perianal region, but arise occasionally from other areas such as the tail, back, and thigh. This report describes two cases of ectopic hepatoid gland adenomas in dogs. The tumors have been observed in the lumbar area of the back and in the axillary region, respectively. The cytological and histopathological features were consistent with hepatoid gland adenoma. Although ectopic hepatoid gland tumors have been described previously in literatures, this is the first report of ectopic hepatoid gland adenoma cases in dogs in South Korea.

• 한국임상수의학회지
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• 제26권6호
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• pp.556-562
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• 2009

피부와 유선 종양은 개에서 매우 빈번히 발생하는 종양으로, 종양 발생의 위험은 나이가 증가함에 따라 종양의 발생률은 증가하며, 발병률과 발병부위의 분포는 종양의 종류마다 다르다. 피부와 유선종양의 발생은 공기오염, 식생활 등 환경의 변화와도 관련이 있어 이들 종양들의 발생양상은 그 사회의 환경을 반영할 수 있어 시대와 지역에 따라 다양하게 다르게 나타날 수 있다. 따라서, 그 동안의 많은 보고들에도 불구하고, 피부와 유선종양발생에 대한 자료들은 종양에 대한 수의임상학적 진단과 치료를 위한 중요한 정보를 제공한다. 본 연구에서는 2005년 1월 1일부터 2006년 12월 31일까지 수의과학검역원과 강원대학교에 의뢰된 128증례의 개 피부종양과 240증례의 개 유선종양을 Goldschmidt와 Misdorp의 형태학적 기준에 의해 조직병리학적으로 진단하여, 종별, 성별 및 부위별로 각각 분류하여 국내에서 이들 종양의 발생양상을 체계적으로 분석하였다. 피부종양에서는 피부상피세포종양, 샘종양 및 간질종양이 각각 14.1%, 41.4%와 44.5%였다. Cutaneous histiocytoma가 피부종양에서 가장 빈번하게 관찰되어 전체 피부종양의 25.0%를 차지하였으며, 기름샘종 (sebaceous gland adenoma; 15.6%), 기저세포종(basal cell tumor; 8.6%), 항문둘레샘종 (perianal gland adenoma; 6.3%)와 지방종 (lipoma; 6.3%)순으로 높았다. 그 외에 비만세포종, 모낭세포종과 중층편평상피암 등이 관찰되었다. 이러한 피부종양들은 품종, 성과 나이 또는 부위에 따라 유사하거나 다른 양상을 나타내었다. 유선종양의 경우 양성과 악성이 201/240, 39/240으로 양성발생률이 현저히 높았으며, 양성혼합종 (benign mixed tumor)이 검사한 품종 모두에서 가장 높은 발생률 (35.0%)을 나타내었다. Complex adenoma는 Maltese와 Poodle에서 특히 높았으며, 악성종양에서는 simple carcinoma와 complex carcinoma가 각각 6.7%로, 악성 중 41.0%를 차지하여 가장 높은 발생률을 나타내었다. 본 연구결과는 최근 우리나라에서 여러 품종의 반려견에서 발생한 피부와 유선종양의 발생양상을 조직병리학적으로 진단 분석한 것으로, 임상수의사들이 지속적으로 증가추세에 있는 개의 피부와 유선종양을 진단하고 치료하는데 유용하게 활용될 수 있기를 기대한다.