• Korean Journal of Acupuncture
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• v.19 no.2
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• pp.63-78
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• 2002

Kupunggibodan(KU), Gamisamul-tang(GA) and Whangryunhaedok-tang(WH) are clinically the most popular prescriptions as an herbal medicine in the treatment of ischemia. In order to compare and evaluate their protective effects on the ischema-induced cognitive deficits by middle cerebral artery occlusion (MCAO), we examined its ability to improve ischemia-induced cell loss and impairements of learning and memory in the Morris water maze and eight-arm radial arm maze. Focal cerebral ischemia produced a marked cell loss, decrease in acetylcholinesterase(AchE) reactivity in the hippocampus, and learning and memory deficits in two behavioral tasks. Pretreatment with WH (100 mg/kg, p.o.) produced a substantial increase in acquisition in the Morris water maze. Pretreatment with KU increased the perfomance of the resention test in the Morris water maze. WH, KU and GA caused a significant improvement in choice accuracy in radial arm maze test. WH was superior to KU and GA in perfomance of the radial arm maze test. Consistent with behavioral data, staining with cresyl violet showed that pretreatments with WH, but not KU and GA significantly recovered the ischemia-induced cell loss in the hippcampal CA1 area. In addition, pretreatments with WH and KU recovered the ischemia-induced reduction of AchE reactivity in the hippocampal CA1 area. These results demonstrated that KU, GA and WH have protective effects against ischimea-induced learning and memory impairments and that the efficacy was the order of WH>KU>GA in tratment of ischemia induced memory deficits. The present studies provide an evidence of KU, GA and WH as putative treatment of vascular dementia. Supported by a fund from the Ministry of Health and Welfare(HMP-00-OO-04-0004), and the Brain Korea 21 Project from Korean Ministry of Education, Korea.

• Journal of the Korea institute for structural maintenance and inspection
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• v.20 no.1
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• pp.18-24
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• 2016

The purpose of this study is to induce the ductile behavior of the Ultra High Perfomance Concrete Reinforced I beam by substituting the part of steel fiber for bundle of reinforcing bars. Experiment of flexural behavior of the Ultra High Performance Concrete I shaped beam with the combination of the steel fiber and bundle of reinforcement bars was carried out. The volume fractions of steel fiber are 0%, 0.7%, 1%, 2%. The bundle of reinforcing bars and prestressing wire are used to restrain the concrete in compression zone. Length of bundle of reinforcing bar and prestressing wire is the one of test factors. The 9 Reinforced UHPC I shaped beam were made with these test factors. Not only steel fiber but also bundle of longitudinal reinforcing bar has effect to induce the ductile behavior of Reinforced UHPC I beam. The combination of 0.7% or 1.0% steel fiber and bundle of reinforcing bar showed the effective ductile behavior of I beam. The relationship of load-deflection and the crack pattern indicate the usefulness of the bundle of the longitudinal bar which has small diameter with close arrangement each other.

• Fire Protection Technology
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• s.28
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• pp.48-54
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• 2000

The technique detects radiant energy form a flaming fire of fuels contained carbonaceous material can be applied to fast growing fires. This technique applied detectors are ultimately effective when early detecting fire alarm system is required or the smoke and heat detectors can not applied. In Korea Fire regulation, a flame detector should be install in case that the installation height is higher than 20[m], chemical plant, hangar refinery. Therefore it is really necessary that a flame detector has to be developed as soon as possible. With foundation technique of flame detector, ideal sensing element and stable circuit design, a trial UV flame detector is manufactured. The stable and reliable technique of flame detector is established through the repeateed perfomance test and modification. An early detecting fire alarm device is developed through the modification, supplement of the structure and circuit. Results of the R & D for the manufacture of an excellent flame detecting device is carried out with the establishment of technique for the mass production and the qualified manufacturing process.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.30 no.4
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• pp.263-272
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• 1994

The hardware and the software of the prototype telemtry system to monitor the behavior of the fish are designed. This system consistes of five parts I. e. three omni-directional hydrophones, three ultrasonic receivers, a single board computer for the signal processing, two RF transceivers for the data communication, and a personnel computer. The sensitivty of the hydrophones is -170dB(re 1V/$\mu$Pa), the gain and the 3dB receiving bandwidth of the ultrasonic receivers are 115dB and 1500Hz respectively, and the sampling period is 33.3$\mu$sec in the signal processing part. The positioning error of the system using hyperbolic method is estimated to be less than 0.2m in case that the pinger locates inside of the baselines. The perfomance of the system considering a practical use was examined by numerical simulation and a water tank test of a pinger tracking experiment. In results, the system developed in prototype was confirmed that it could be useful for monitoring the behavior of fish in the limited water area.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2006.11a
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• pp.439-443
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• 2006

In this paper, a design of milli-gripper using piezoelectric actuator and flexible hinge structure has been suggested, and the dynamic characteristics of the milli-gripper has been analysed and improved. The milli-gripper consists of the operating and amplifier parts, and the perfomance of the gripper be heavily influenced by base excitation disturbances. The dynamic characteristics of milli-gripper has been measured by the FRF based on experimental modal analysis. It has been found by a series of experiments that the performance of the milli gripper using PID control is made a remarkable improvement in terms of gripping forces.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1995.10a
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• pp.1191-1194
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• 1995

A conversational programming system for turning processes was studied to enhance the user friendlness of an NC by adopting man-machine interface functions through Visual C $^{++}$ programming tool under the Windows 95 environment. Shop floor programming performance was incorporated in the developed CAM module. In order to increase flexibility of the man-machine interface, graphic based programmin tool have been developed. An NC turning machine equipped whit an open architecture PCNC was used as a test bed of the system. Perfomance of the system was verified through case studies..

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1994.04a
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• pp.627-632
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• 1994

This study suggests the contingency framework understanding the implementation of NIMT and conducts empirical analysis using survey data. The main objectives of the thesis are as follows : (1) analyzing the relationship between adaptation requirements and organizational adaptation efforts. (2) analyzing the relationship between organizational adaptation efforts and implementation performance, and the moderating effect of the adaptation requirements. (3) analyzing the relationship between organizational adaptation efforts and organization characteristics(organization size, technical capability, top management support). A field study was undertaken to test the hypothesized relationships among adaptation efforts, adaptations requirements, organization characteristics, implementation performance. Data were collected from 52 NMT implementation projects of 45 machine tool, metal component firms. The emprical relflts indicated that adaptation requirrnents, organization characteristics were significantly related to organizational adaptation efforts and adaptation efforts can significantly improve implementation perfomance, but the moderating effect of adaptation requirements on adaptation efforts and implementation performance was not supported.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2000.10a
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• pp.217-221
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• 2000

Nonlinear stress analysis of nuclear containment building wall element is carried out using microscopic material model. The present study mainly focuses on the finite element analysis of the nuclear containment building wall element under biaxial tensile stresses and it evaluates the perfomance of adopted microscopic material model in the membrane energy dominant situation. From the numerical analysis, the adopted material model peforms well and has a good agreement with experiment result. Finally, the result of present study can be severed as a benchmark test when concrete material model is in need of evaluation.

• Proceedings of the Korea Concrete Institute Conference
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• 2005.11a
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• pp.57-60
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• 2005

The objective of this paper is to investigate and analyze the behaviour of prestressed I section structural members constructed with ultra high perfomance steel fiber reinforced cementitious concrete (SFR-UHPC). This material is known as reactive powder concrete (RPC) mixed with domestic materials and its compressive strength is over 150MP. The parameters of test specimens were span to depth ratio, prestressing force, prestressing wire placement and web width. Most influential parameter to determine the failure mode between shear and flexural action was proved to be shear span ratio. The characteristics of ultra high-strength concrete is basically brittle, but due to the steel fiber reinforcement behaviour of this structure member became ductile after the peak load. As a result of the test, the stress block of compressive zone should be redefined. The proposed analytical calculation of internal force capacity based by plastic analysis gave a good prediction for the shear and flexural strength of specimens. The numerical verification of the finite element model which constitutive law developed for Mode I fracture of fiber reinforced concrete correctly captured the overall behaviour of the specimens tested.

• YAKHAK HOEJI
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• v.38 no.5
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• pp.586-594
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• 1994

The general pharmacological effects of DWQ-013, a new synthetic quinolone antibacterial agent, were examined on the central nervous system in experimentral animals and the following results were obtained. Drug interaction of DWQ-013 with theophylline, fenbufen and nonsteroidal antiinflammatory drugs was also examined. DWQ-013 decreased touch escape effect on the general behavior and decreased body temperature at a concentration of 1000 mg/kg in mice. But DWQ 013 had no effect on the locomotor activity, rotarod perfomance and traction test in mice. Furthermore, DWQ-013 increased pentobarbital-induced sleeping time and affected the onset time in acetic acid-induced writhing test in mice. DWQ-013 reduced onset time and death time on strychnine-induced convulsions and death time on pentylenetetrazole-induced convulsions at a concentration of 1000 mg/kg in mice. But, the drug had no effect on the electroshock. DWQ-013 did not interact with fenbufen and any other NSAIDs but it did interact with theophylline. From these results, it could be suggested that DWQ-013 had less pharmacological effect than other quinolones on the central nervous system.