• 척추신경추나의학회지
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• 제16권1호
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• pp.25-34
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• 2021

Objectives This review was conducted to evaluate the effectiveness and clinical significance of Chuna manual therapy (CMT) in the treatment of pediatric cough. Methods Ten electronic databases (PubMed, EMBASE, Cochrane, CNKI [CAJ], KMBASE, KISS, KISTI, NDSL, RISS, and Oasis) were searched. Only randomized controlled trials (RCTs) using CMT for pediatric cough treatment were included. The methodological quality of each RCT was evaluated using the Cochrane risk-of-bias tool (v1.0). Results Nine RCTs met the inclusion criteria. The meta-analysis revealed positive effects of CMT in the treatment of pediatric cough. Both CMT alone and CMT combined with Chinese medication or Chinese medicine acupoint application (CMAA) were effective in treating pediatric cough. Conclusions This systematic review shows the reliability, effectiveness, and clinical significance of CMT in the treatment of pediatric cough. However, the evidence is limited due to the defective design of the included RCTs. More well-designed RCTs are required to provide clearer evidence for this claim.

• 대한한방소아과학회지
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• 제14권1호
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• pp.153-168
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• 2000

The cough is one of the most common respiratory symptom in children. Boeumjunggi-tang(BEJG) is herbal medicine mainly treat cough due to yin deficiency(陰虛咳嗽) in Oriental Medicine. During 3 momths from February, 1, 2000 to April, 30, 2000, BEGJ is administered to the pediatric out-patients with the cough due to yin deficiency have visited Pundang Dongguk Oriental medicine Hospital and among these patients, this study is performed for 50 patients of which the result of treatment could be gained. The conclusion is following. 1. In the distribution of patients, male(60%) is more than female(40%) and group of age in between 1 and 6 years(76%) are the first. 2. In the type of cough, group of chronic(more than 3 weeks), and group that the symptom make worse in night are the most. 3. In the distribution of remedial effect, group of symptom-relieved is the first(58%), symptom-disappearing is second(22%), symptom-unchanging is third(14%), symptom-aggravated is fifth(6%). 4. The chracteristic of cough have little influence on the remedial effect of BEGJ.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제1권1호
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• pp.115-119
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• 1998

Congenital bronchoesophageal fistula associated esophageal atresia usually presents in the newborn period or infancy but those without esophageal atresia are more insidious in disease process. Symptoms which include cough, hemoptysis, choking on swallowing liquids, uncommonly dysphagia, and epigastric discomfort may not begin until adult life. Most of the cases are curative unless there are serious underlying conditions. The diagnosis is usually made by gastroesophagoscopy, esophagogram, bronchogram and bronchoscopy. And the most of the cases can be cured by fistulectomy and resection of involved pulmonary lobes. We experienced one case of congenital bronchoesophageal fistula which occurred in a 13- year-old girl who complained of paroxysmal cough and intermittent hematemesis for 3 years.

• 대한소아치과학회지
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• 제34권4호
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• pp.590-598
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• 2007

유아용 시럽형 약물은 어린이가 쉽게 복용할 수 있도록 여러 종류의 당분을 감미제로 사용하고 있으며 그로 인한 우식의 위험이 높다고 할 수 있다. 그러나 시럽형 약물의 우식유발성에 대한 보호자의 인지도는 매우 낮으며 의료 종사자들 조차 이를 소홀히 여기고 있어 문제의 심각성이 크다고 할 수 있다. 본 연구는 시럽형 약물이 구강 내 산도에 미치는 영향에 대하여 조사할 목적으로, 15 종의 시럽형 약물의 산도를 조사하고, 그 중 널리 시판되는 4종을 선택하여 이 약물들이 치태의 산도 변화에 미치는 영향을 평가하였다. 또한 가장 흔하게 사용하는 유아용 시럽형 약물의 일종인 코푸시럽의 복용방법에 따른 타액의 산도 변화를 측정하여 다음과 같은 결과를 얻었다. 1. 15 종 시럽형 약물의 산도는 pH $3.0{\sim}6.8$의 범위에서 다양하여 평균 pH $4.7{\pm}0.94$로 나타났다. 2. 치태의 산도변화를 측정하기 위해 선정된 4종의 시럽형 약물 모두는 구강 내 투입 직 후 법랑질의 탈회 임계점인 pH 5.5 이하로 치태의 산도를 급격히 떨어뜨렸으며, 시간 경과에 따른 치태의 산도 변화에서 콜디(종합 감기약)를 제외한 모든 약물에서는 유의한 차이가 없었다(p>0.05). 3. 코푸 시럽으로 구강을 헹구어낸 경우와 코푸 시럽에 이어 물로 구강을 헹구어낸 경우 타액의 산도 변화에 있어서는 유의한 차이가 있었다(p<0.05).

• 대한한방소아과학회지
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• 제37권3호
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• pp.75-93
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• 2023

Objectives We aimed to analyze the registration status of interventional clinical trials in children and adolescents with chronic cough. Methods All interventional clinical trials registered up to 3 July, 2023 on the international clinical trial registry platform (ICTRP) of the World Health Organization (WHO) were analyzed. Information was extracted including study design, interventions, inclusion and exclusion criteria, and outcome indicators. Results A total of 18 interventional clinical trials were analyzed. For study design, multicentre trials, randomized allocation, parallel group design and phase 4 trials were the most frequently reported. Blinding was used in 44.4% and informed consents were obtained from 61.1%. For intervention, drugs were used in 61.1%, using placebo control group in 27.8%. Quality of life questionnaires were most frequently reported in 50% as the primary outcome, and adverse events were the most as the secondary outcome. In most cases, the assessment timepoints were after two weeks. Conclusions Based on the characteristics of clinical trial design analyzed in this study, it is necessary to design traditional Korean medicine clinical trials with improved quality and accuracy of information.

• 대한한방소아과학회지
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• 제17권1호
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• pp.99-115
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• 2003

Pneumonia is an acute or recurrent infection of the parenchyma of the lung causing cough, fever, and respiratory distress. Pneumonia was named 'Feiyanchuansou(肺炎喘嗽)' in chinese medicine. This study was progressed for oriental medical treatment for pediatric pneumonia in china. The purpose of this study is current oriental medical approach to pediatric pneumonia In this study, the authors tried to figure out the cause of the pediatric pneumonia and its treatment and came to the conclusion as follows: 1. The study for pediatric pneumonia consists of basic, clinical and experimental study. 2. Basic study consists of etiology and pathogenesis(病因病耭), the rule of treatment(治療原則) and method of treatment(治法). 3. Clinical study consists of symptoms-based treatment(辨證論治), adequate prescription treatment(專病專方), acupuncture(鍼灸治療), and western diagnosis based treatment. 4. The majority of experimental study was pharmacology that consists of antiviral and antibacterial effect, removing heat(淸熱), releasing pulmonary qi(宣肺), dissipating phlegm(化痰).

• Allergy, Asthma & Immunology Research
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• 제10권6호
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• pp.591-613
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• 2018

Chronic cough is common in the community and causes significant morbidity. Several factors may underlie this problem, but comorbid conditions located at sensory nerve endings that regulate the cough reflex, including rhinitis, rhinosinusitis, asthma, eosinophilic bronchitis, and gastroesophageal reflux disease, are considered important. However, chronic cough is frequently non-specific and accompanied by not easily identifiable causes during the initial evaluation. Therefore, there are unmet needs for developing empirical treatment and practical diagnostic approaches that can be applied in primary clinics. Meanwhile, in referral clinics, a considerable proportion of adult patients with chronic cough are unexplained or refractory to conventional treatment. The present clinical practice guidelines aim to address major clinical questions regarding empirical treatment, practical diagnostic tools for non-specific chronic cough, and available therapeutic options for chronic wet cough in children and unexplained chronic cough in adults in Korea.

• 대한한방소아과학회지
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• 제24권2호
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• pp.75-87
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• 2010

Objectives Halitosis affects a large proportion of the population, and it may cause a significant social or psychological problems but pathophysiological mechanism of halitosis is unclear. The purpose of this study is to investigate pediatric halitosis patients' characteristics and their related symptoms. Methods 133 patients were participated at the Pediatric Clinic of Kyanhee Oriental Medical Center from May 29th, 2010 to July 10th, 2010. We measured sulfide level and reviewed medical charts and asked some questions. Patients of sex, age, respiratory symptoms, digestive symptoms, systemic symptoms and sulfide level were analyzed. Results Stuffy nose, cough after sleep, sputum, snoring, indigestion, stomachache, motion sickness, and Bi-We-Soo diagnosis grades were significantly associated with halitosis Conclusions Based on data, we found that halitosis is related to the respiratory and digestive symptoms. Also, we can refer this study when diagnosing patients or giving treatments to patients.

• Clinical and Experimental Pediatrics
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• 제54권4호
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• pp.141-145
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• 2011

Pertussis is an acute respiratory infection characterized by paroxysmal cough and inspiratory whoop for over 2 weeks. The incidence of pertussis has decreased markedly after the introduction of DTwP/DTaP vaccine, but the incidence of pertussis has increased steadily among young infant and among adolescents and adults in many countries. Td vaccine was used in this age group but the increase in pertussis has lead to the development of a Tdap vaccine. The Tdap vaccine is a Td vaccine with a pertussis vaccine added and is thought to decrease the incidence and transmission of pertussis in the respective age group. In Korea, two products are approved by the KOREA FOOD & DRUG ADMINISTRATION, which are ADACEL$^{TM}$ (Sanofi-Pasteur, Totonto, Ontario, Canada) and BOOSTRIX$^{(R)}$ (GlaxoSmithKline Biologicals, Rixensart, Belgium) for those aged between 11-64. This report summarizes the recommendations approved by the Committee on Infectious Diseases, the Korean Pediatric Society.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제19권3호
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• pp.207-209
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• 2016

Benzalkonium chloride (BAC) is a caustic agent which is used in farms, homes and hospitals for cleaning skin and wounds as an antiseptic solution. It may lead to digestive system injuries in case of ingestion. We present a two-days-old newborn case which was carried to the emergency unit with complaints of poor breastfeeding, uneasiness and crying for 4-6 hours. Her mom confessed that she had given a spoon of 10% BAC solution for her cough. Initial laboratory tests were in normal ranges. A gastroscopy performed in the second hour of her admission revealed an hyperemic and edematous mucosa in the middle third of esophagus and a circumferential ulceration followed in the distal portion. Hereupon, a conservative treatment for 10 days was administered and the control gastroscopy demonstrated that the damage was almost totally improved. She was the youngest case with this etiology and successfully treated with conservative approach.