• KSBB Journal
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• v.18 no.2
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• pp.100-106
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• 2003

An on-line frontal analysis HPLC system was developed to determine the unbound concentration of (S)-perillyl alcohol, an potential anti-cancer agent, in human serum albumin (HSA) solution, The analysis was performed on a Develosil 100 Diol 5 (10 cm x 4.6 mm I.D.) high-performance frontal analysis (HPFA) column. Sodium phosphate solution was used as the mobile phase (pH 7.4, ionic strength 0.17) at a flow rate of 1 $m\ell$/min. UV wavelength was set at 205 nm. A injection volume of 600${mu}ell$ was chosen to ensure the compound eluted formed a zonal peak with a plateau. By Scatchard analysis, it was found that the binding constant(K) and binding number(n) of (S)-perillyl alcohol to molecular HSA were 2.05 x $10^6$ [$M{-1}$], 0.00428, respectively.

• Physical Therapy Korea
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• v.14 no.4
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• pp.44-49
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• 2007

The purpose of this study was to investigate the effects of auditory cues in the form of a metronome on gait initiation (GI) in Parkinson's disease (PD). 2 patients (mean age: 54 yrs) with idiopathic PD participated in the study. All patients (Hoehn and Yahr disability score of 2.0) were tested in the "on" state approximately 1.5 hours following the administration and fully responding to their PD medications. Subjects first initiated walking at self-initiated speeds to determine their cadences. Then, subjects were asked to initiate gait along the walkway while keeping pace with a metronome. The metronome rate (in beats/min) was set at a cadence 85% (slow condition), 100% (normal condition) and 115% (fast condition) of gait for each subject. Subjects were able to increase the speed of GI with faster cadence, but the speed of GI for the slow condition was similar to that of the normal condition. Swing toe-off was 578.3 ms for the fast condition, 709.4 ms for the normal condition and 736.2 ms for the slow condition. Respective times for swing heel-strike were 894.3 ms, 1110.2 ms and 1119.1 ms, and stance toe-off were 1105.4 ms, 1338.5 ms, and 1343.1 ms. Except for stance unloading ground reaction forces were greatest for the fast condition and smallest for the slow condition. It appears that PD patients were able to modulate GRFs and temporal events in response to auditory cues to achieve the peak acceleration force of the swing and stance limb. The findings from this study provided preliminary data, which could be used to investigate how PD patients modulate GRFs and temporal events during GI in response to tasks.

• Computers and Concrete
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• v.1 no.3
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• pp.325-354
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• 2004

Slabs in buildings and bridge decks, which are restrained against lateral displacements at the edges, have ultimate strengths far in excess of those predicted by analytical methods based on yield line theory. The increase in strength has been attributed to membrane action, which is due to the in-plane forces developed at the supports. The benefits of compressive membrane action are usually not taken into account in currently available design methods developed based on plastic flow theories assuming concrete to be a rigid-plastic material. By extending the existing knowledge of compressive membrane action, it is possible to design slabs in building and bridge structures economically with less than normal reinforcement. Recent research on building and bridge structures reflects the importance of membrane action in design. This paper describes the finite element modelling of membrane action in reinforced concrete slabs through optimisation of a simple concrete model. Through a series of parametric studies using the simple concrete model in the finite element simulation of eight fully clamped concrete slabs with significant membrane action, a set of fixed numerical model parameter values is identified and computational conditions established, which would guarantee reliable strength prediction of arbitrary slabs. The reliability of the identified values to simulate membrane action (for prediction purposes) is further verified by the direct simulation of 42 other slabs, which gave an average value of 0.9698 for the ratio of experimental to predicted strengths and a standard deviation of 0.117. A 'deflection factor' is also established for the slabs, relating the predicted peak deflection to experimental values, which, (for the same level of fixity at the supports), can be used for accurate displacement determination. The proposed optimised concrete model and finite element procedure can be used as a tool to simulate membrane action in slabs in building and bridge structures having variable support and loading conditions including fire. Other practical applications of the developed finite element procedure and design process are also discussed.

• Journal of IKEEE
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• v.19 no.3
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• pp.282-287
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• 2015

In this study, an optical fiber detector was constructed by using a Ce:GAGG scintillator, optical fiber, and photomultiplier. The single crystal size of the scintillator was set to $3{\times}3{\times}20mm^3$ after simulating the counting efficiency of gamma rays in the scintillator by using the MCNPX code. The constructed detector used the standard gamma ray sources $^{137}Cs$ and $^{133}Ba$ to measure radiation and analyze the spectral characteristics of gamma rays. The resulting trend curve showed excellent linearity with an R-squared value of 0.99741, and the detector characteristics were found to vary 2% or less with distance based on comparison with the MCNPX value. Furthermore, the spectroscopic analysis of the gamma ray energy from the single-ray and mixed-ray sources showed that $^{137}Cs$ had its peak energy at 662 keV, and $^{133}Ba$ had at 356 keV. It seems that if the fiber-optics detector is used, working hours and exposure of worker can be reduced.

• Journal of Fisheries and Marine Sciences Education
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• v.24 no.5
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• pp.662-669
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• 2012

Bycatch and stranding of sea turtles from Jeju coastal water of Korea were monitered from 2008 to 2009. A total of 41 sea turtles, consisting of 12 greens (Chelonia mydas), 3 loggerheads (Caretta caretta), 1 hawksbill (Eretmochelys imbricata) and 25 unidentified species, were recorded and observed in those area. Reported stranding and bycatch reached to a peak in August. The largest number of bycatch occurred in the coastal waters around Aewol-eup located in northwest area of Jeju Island. Most of the bycatch were taken by set nets and gill nets, which prevailed over the fishing grounds in the coastal waters of the Jeju Island. It is suggested that an appropriate monitoring system be necessary to conserve endangered sea turtle species in Jeju of Korea.

• Korean Journal of Applied Biomechanics
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• v.25 no.3
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• pp.283-291
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• 2015

Objective : The purpose of this study was to determine the differences in the head and tibial acceleration signal magnitudes, and their powers and shock attenuations between flat-footed and normal-footed running. Methods : Ten flat-footed and ten normal-footed subjects ran barefoot on a treadmill with a force plate at 3.22m/s averaged from their preferred running speed using heel-toe running pattern while the head and tibial acceleration in the vertical axis data was collected. The accelerometers were sampled at 2000 Hz and voltage was set at 100 mv, respectively. The peak magnitudes of the head and tibial acceleration signals in time domain were calculated. The power spectral density(PSD) of each signal in the frequency domain was also calculated. In addition to that, shock attenuation was calculated by a transfer function of the head PSD relative to the tibia PSD. A one-way analysis of variance was used to determine the difference in time and frequency domain acceleration variables between the flat-footed and normal-footed groups running. Results : Peaks of the head and tibial acceleration signals were significantly greater during flat-footed group running than normal-footed group running(p<.05). PSDs of the tibial acceleration signal in the lower and higher frequency range were significantly greater during flat-footed running(p<.05), but PSDs of the head acceleration signal were not statistically different between the two groups. Flat-footed group running resulted in significantly greater shock attenuation for the higher frequency ranges compared with normal-footed group running(p<.05). Conclusion : The difference in impact shock magnitude and frequency content between flat-footed and normal-footed group during running suggested that the body had different ability to control impact shock from acceleration. It might be conjectured that flat-footed running was more vulnerable to potential injury than normal-footed running from an impact shock point of view.

• Journal of The Korean Astronomical Society
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• v.50 no.6
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• pp.157-165
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• 2017

$H_2O$ maser emission at 22 GHz in the circumstellar envelope is one of the good tracers of detailed physics and kinematics in the mass loss process of asymptotic giant branch stars. Long-term monitoring of an $H_2O$ maser spectrum with high time resolution enables us to clarify acceleration processes of the expanding shell in the stellar atmosphere. We monitored the $H_2O$ maser emission of the semi-regular variable R Crt with the Kagoshima 6-m telescope, and obtained a large data set of over 180 maser spectra over a period of 1.3 years with an observational span of a few days. Using an automatic peak detection method based on least-squares fitting, we exhaustively detected peaks as significant velocity components with the radial velocity on a $0.1kms^{-1}$ scale. This analysis result shows that the radial velocity of red-shifted and blue-shifted components exhibits a change between acceleration and deceleration on the time scale of a few hundred days. These velocity variations are likely to correlate with intensity variations, in particular during flaring state of $H_2O$ masers. It seems reasonable to consider that the velocity variation of the maser source is caused by shock propagation in the envelope due to stellar pulsation. However, it is difficult to explain the relationship between the velocity variation and the intensity variation only from shock propagation effects. We found that a time delay of the integrated maser intensity with respect to the optical light curve is about 150 days.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.5
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• pp.1111-1121
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• 2015

Roundabouts face a congestion problem when there are unbalanced traffic conditions, especially during peak times. The congestion at roundabouts results in long delay times and low level of service. Some research has addressed congestion problems of the metering roundabout, however, few studies have focused on the congestion issues of the double signals metering roundabout. This research bridges this gap through analyzing the congestion issues of the Old Belair double signals roundabout in Adelaide. The research proposes a new analysis method based on a four-nodes intersection in order for double signals roundabout analysis to be carried out as follows: firstly, at the modeling stage, a connection of four individual intersections, adjustment of lane geometry, input of directional traffic volumes, priority and phase time set up are proposed. Secondly, for calibration, PFF, critical gap, follow-up headway and extra bunching values have been applied. The results from the analysis show that the new method is able to analyze the delay time, level of service, degree of saturation and allow for further analysis.

• Journal of Korean Society for Geospatial Information Science
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• v.5 no.2 s.10
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• pp.77-85
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• 1997

Researches in the field of Computer Graphics and Geographical Information Systems(GIS) have extensively studied the method of photo-realistic landscape modelling, because it have become a commom requirement in applications such as flight simulators, mission rehearsal, and construction planning. A common approach to the display of terrain uses a Digital Elevation Model(DEM). DEM is an evenly spaced array of the terrain elevation data and can be obtained from stereo satellite data. With the DEM data, the process of 3D terrain modelling consists of three steps. The first step is to extract the meaningful data (such as peak, pit, passes...) from DEM data based on LOD(Level Of Detail) criteria. The second is to construct the 3D surface by TIN, which represents a surface as a set of non-overlapping continuous triangular facets of irregular size and shape. The third is a rendering of 3D terrain model. The goal of this research is a construction of 3D terrain with TIN. To do this, we are going to app]y Radial Sweep Algorithm. Radial Sweep Algorithm for generating TIN works quickly and efficiently. However, it does not solve the problem caused by the approximated nature of triangulated surface. To solve this problem, this research derive improved radial sweep algorithms with the optimal triangle definition.

• The Journal of the Korea Contents Association
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• v.13 no.11
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• pp.617-625
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• 2013

Along with and <1Q84> Murakami Haruki sees through human nature that fades away with time in his latest work with 'color and memory'. This is the type of character or story to read with the deployment of instrument. Costume of characters conceived in the expansion of the body, the inner expression of personal notes. To others what you want to look, how they formed on the body, with a range of social, if you are claiming a statement. To form the body by forming self-practice is that there becomes. This paper the inside of the characters and the apparent strong interest in the set, costume characters, especially characters were recognized as representing the device of novel. Work directly in the results, or is described as a symbolic system of the body and clothing that embodies the meaning of the symbol you want to the structure of the exchange.