• 응용통계연구
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• 제33권3호
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• pp.269-280
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• 2020

시간경로 유전자 발현 자료는 마이크로어레이 실험을 시간에 따라 관측한 대용량의 자료로 유전자 발현 수준을 동시에 파악할 수 있다. 하지만 실험 과정이 복잡하여 다양한 원인들에 의해 결측값이 자주 발생한다. 본 논문에서는 시간경로 유전자 발현 자료에 대한 결측값을 추정하는 방법으로 패턴 적응 최근접 이웃(pattern consistency index adaptive nearest neighbors; PANN) 방법을 제안하였다. 이 방법은 국소적 특징을 반영하는 적응 최근접 이웃(adaptive nearest neighbors; ANN) 방법과 관측 시점간 유전자 발현의 일치 정도를 고려하는 패턴일치지수를 결합시킨 것이다. 제안한 PANN 방법의 효능을 평가하기 위하여 두 가지의 실제 시간경로 자료들을 사용하여 몬테카를로 모의실험(Monte Carlo simulation study)을 시행하였다.

• 응용통계연구
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• 제18권2호
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• pp.371-379
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• 2005

본 논문에서는 피어슨 상관계수를 이용한 시간경로 유전자 발현자료의 군집분석에서 군집의 대표적인 패턴에서 벗어나는 이질적인 패턴을 보이는 시계열을 탐지하기 위한 패턴일치지수를 제안하고, 이를 마이크로어레이 실험으로부터 얻어진 혈청 시간경로 유전자 발현자료에 적용하여 유용성을 검토해 본다.

• 대한화장품학회지
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• 제25권4호
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• pp.65-74
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• 1999

We have studied the stability of W/O high internal phase emulsions(HIPE) containing water, cetyl dimethicone copolyol and oils varying magnesium sulfate in the range 0 to 0.5 wt% and oil polarities, respectively. The rheological consistency was mainly destroyed by the coalescence of the deformed water droplets. The greater the increase of complex modulus was, the less coalescence occurred and the more consistent the concentrated emulsions were. The increasing pattern of complex modulus versus volume fraction has been explained with the resistance to coalescence of the deformed interfacial film of water droplets in concentrated W/O emulsion. The stability is dependent on: (i) the choice of the oil is important, the requirements coincide with the requirements for the formation of the rigid liquid crystalline phases; and (ii) addition of salts the aqueous phase opposes the instability due to coalescence. Increasing the salt concentration increases the refractive index of the aqueous phase. It lowers the difference in the refractive index between the oil and aqueous phases. This decreases the attraction between the water domains, thus increasing the stability.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 1999년도 IFSCC . ASCS 학술대회 발표 논문
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• pp.65-74
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• 1999

We have studied the stability of W/O high internal phase emulsions(HIPE) containing water, cetyl dimethicone copolyol and oils varying magnesium sulfate in the range 0 to 0.5wt% and oil polarities, respectively. The rheological consistency was mainly destroyed by the coalescence of the deformed water droplets. The greater the increase of concentrated modulus was, the less coalescence occurred and the more consistent the concentrated emulsions were. The increasing pattern of complex modulus versus volume fraction has been explained with the resistance to coalescence of the deformed interfacial film of water droplets in concentrated W/O emulsion. The stability is dependent on: (i) the choice of the oil is important, the requirements coincide with the requirements for the formation of the rigid liquid crystalline phases :5; and (ii) addition of salts the aqueous phase opposes the instability due to coalescence:. Increasing the salt concentration increases the refractive index of the aqueous phase. It lowers the difference in the refractive index between the oil and aqueous phases. This decreases the attraction between the water domains, thus increasing the stability.

• 대한토목학회논문집
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• 제37권4호
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• pp.669-680
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• 2017

본 연구에서는 하천의 갈수관리를 위한 기준유량과 가뭄지수와의 일관성 분석을 수행하기 위해서, 국토교통부 홍수통제소에서 고시한 37개 갈수예보 관리지점 중 섬진강 수계의 구례2지점과 형산강 수계의 안강지점을 대상으로 하여 관측된 일별 유량 자료를 구축하였으며, 더불어 인근 기상관측소 남원지점과 포항지점의 강우량 자료를 활용하였다. 본 연구에서는 하천 유량자료를 기반으로 한 수문학적 가뭄상황을 재현해줄 수 있는 유량누가가뭄지수(SADI)를 개발하였다. SADI는 유량패턴의 변동시점(Change-Point) 분석을 통해 가뭄절단수준을 결정하였고, 또한 감소계수 추정을 위해 핵밀도함수를 이용하였다. 이처럼 계산된 SADI는 표준유출지수(SRI), 표준강수지수(SPI)와 비교되었으며, 이 중 SRI와 SPI는 30일, 90일, 180일, 270일 시간단위에 대한 가뭄지수를 모두 산정한 후, ROC 곡선 분석을 이용하여 갈수예보 기준유량과 일관성이 가장 높은 시간단위를 최종 결정하였다. 갈수예보 지점의 관심단계 예보기준유량을 기반으로 하여 다양한 가뭄지수와의 ROC 곡선 분석을 실시한 결과, 섬진강 수계의 구례2지점은 SADI_C3, SRI30, SADI_C1, SADI_C2, SPI90의 순으로 갈수예보의 정확도가 높은 것으로 나타났다. 또한, 형산강 수계의 안강지점은 SADI_C3, SADI_C1, SPI270, SRI30, SADI_C2의 순으로 갈수예보의 정확도가 높은 것으로 나타났다.

• 한방비만학회지
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• 제16권1호
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• pp.1-10
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• 2016

Objectives: The purpose of this study was to develop Russian version of Korean obese pattern identification questionnaire (KOPIQ) and classify the pattern of Uzbekistan obese patients. Methods: This study was conducted from 10 September 2014 to 10 December 2014 in Korea-Uzbekistan Oriental Hospital. The KOPIQ was translated to Russian language with the help of local expert in Russia and Korean Medicine. The patients who visited obese clinic in hospital were guided to join this study and informed consent was obtained. The inclusion criteria was >$23kg/m^2$ in body mass index. The Cronbach's alpha was used for it's inter consistency reliability and the KOPIQ result was compared with the experts one. Results: The Russian version of KOPIQ was developed. The 103 patient (25 males, 78 females; average age 57.2 years) joined in this study. The Cronbach's alpha of questionnaire was 0.787~0.883 according to individual pattern. The agreement rate of pattern Identification between local expert and KOPIQ was 13%. This developed questionnaire was realized as web version, which could be easily used in Uzbekistan. Conclusions: The Russian version of KOPIQ is developed in this study with suitable reliability. Further study is needed for KOPIQ to be applied in Uzbekistan with high validity.

• 한국철도학회논문집
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• 제12권2호
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• pp.260-266
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• 2009

위험도분석은 철도사고해석에 주로 사용되는 이론이다. 위험도 분석의 목적은 전설공사전체 과정에서 주요사고부 사고요인과 잠재적인 원인 및 기여정도 등을 조사 분석하는 것이다. 본 논문은 건설공사 현장에서 발생하는 사고원인과 패턴을 분석하고 사고빈도와 심각도를 고려한 위험도 지수를 계산하여 상대적인 위험도 평가를 제공하고자 하는 것이다. 이를 기반으로 사고 위험도 지수의 일관성을 유도하고 위험도 평가를 위한 정량적인 기준을 제공하고자 하였다.

• 대기
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• 제16권3호
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• pp.225-234
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• 2006

Convective systems propagate eastward with a persistent pattern in the longitude-time space. The characteristic structure and fluctuation of convective system is helpful in determining its predictability. In this study, convective index (CI) was defined as a difference between GOES-9 window and water vapor channel brightness temperatures following Mosher (2001). Then the temporal-spatial scales and variational characteristics of the summer convective systems in the East Asia were analyzed. It is found that the average moving speed of the convective system is about 14 m/s which is much faster than the low pressure system in the summer. Their average duration is about 12 hours and the average length of the cloud streak is about 750km. These characteristics are consistent with results from other studies. Although the convective systems are forced by the synoptic system and are mostly developed in the eastern edge of the Tibetan Plateau, they have a persistent pattern, i.e., appearance of the maximum intensity of convective systems, as they approach the Korean Peninsula. The consistency of the convective systems, i.e., the eastward propagation, suggests that there exists an intrinsic predictability.

• 보건행정학회지
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• 제20권3호
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• pp.21-35
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• 2010

This study examined the changes in the service mix of Korean hospitals in 6 metropolitan cities between 2003 and 2005, and assessed whether the sample hospitals exhibit consistent trend or chance variation in multiple years. Three measures of hospital service mix, focusing on the specialization of services, were applied: information theory index, internal Herfindahl index, and number of distinct diagnosis-related groups (DRGs) treated. National Health Insurance claims were used to calculate the indexes. Specialization indexes were calculated in each year, and then examined to identify the pattern over time. Kappa analysis was applied to assess the agreements of specialization score between two years after hospitals were categorized into 4 groups with quartiles. Kappa score showed that the service mix of hospitals were changed during the study years. Specialization scores were increased given the market structure for three years. Hospitals which showed higher or lower specialization scores than the average of the scores consistently classified into the same group. Specialization indexes showed relatively consistent pattern over 3 years, and such consistencies were evident for hospitals regardless of the specialization status. Policy makers can identify the degree of specialization with the indexes, and it could provide a picture of how hospital services were mixed and changed over time.

• 한방재활의학과학회지
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• 제29권3호
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• pp.113-128
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• 2019

Objectives To evaluate the pattern identification tool for knee osteoarthritis and to investigate the relationship between pattern identification tool and knee ROM (range of motion), VAS (visual analog scale) and WOMAC (Western Ontario & McMaster Universities osteoarthritis index). Methods We studied 50 patients who are diagnosed as degenerative osteoarthritis. With one patient dropping out, total of 49 patient went through pattern identification tool. Re-test of the pattern identification tool was implemented after about a week. The reliability was analyzed by calculating ICC (intraclass correlation coefficient). Also, reliability of each pattern identification score was calculated along with influence factor and correlation between knee ROM, VAS and WOMAC. Results Reliability of the pattern identification tool was evaluated as 'poor agreement beyond chance' with ICC value of 0.396. Reliablility of each pattern identification score was calculated and four out of five were measured 'good' with one 'moderate' reliability. Two of inter-item consistency were 'good', two were 'acceptable' and one was 'questionable'. Correlation between each pattern identification and knee ROM showed 'clear negative linear relationship' with two patterns. VAS showed 'clear positivie linear relationship' with all five patterns. WOMAC showed 'positivie linear relationship' with all five patterns. Conclusions According to the results, pattern identification tool for knee osteoarthritis seems to have meaningful relationship with other agnedas. Also, further research is needed to develop the tool.