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An Index Structure for Substructure Searching In Chemical Databases (화학 데이타베이스에서 부분구조 검색을 위한 인덱스 구조)

  • Lee Hwangu;Cha Jaehyuk
    • Journal of KIISE:Databases
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    • v.31 no.6
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    • pp.641-649
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    • 2004
  • The relationship between chemical structures and biological activities is researched briskly in the area of 'Medicinal Chemistry' At the base of these structure-based drug design tries, medicinal chemists search the existing drugs of similar chemical structure to target drug for the development of a new drug. Therefore, it is such necessary that an automatic system selects drug files that have a set of chemical moieties matching a user-defined query moiety. Substructure searching is the process of identifying a set of chemical moieties that match a specific query moiety. Testing for substructure searching was developed in the late 1950s. In graph theoretical terms, this problem corresponds to determining which graphs in a set are subgraph isomorphic to a specified query moiety. Testing for subgraph isomorphism has been proved, in the general case, to be an NP- complete problem. For the purpose of overcoming this difficulty, there were computational approaches. On the 1990s, a US patent has been granted on an atom-centered indexing scheme, used by the RS3 system; this has the virtue that the indexes generated can be searched by direct text comparison. This system is commercially used(http://www.acelrys.com/rs3). We define the RS3 system's drawback and present a new indexing scheme. The RS3 system treats substructure searching with substring matching by means of expressing chemical structure aspredefined strings. However, it has insufficient 'rerall' and 'precision‘ because it is impossible to index structures uniquely for same atom and same bond. To resolve this problem, we make the minimum-cost- spanning tree for one centered atom and describe a structure with paths per levels. Expressing 2D chemical structure into 1D a string has limit. Therefore, we break 2D chemical structure into 1D structure fragments. We present in this paper a new index technique to improve recall and precision surprisingly.

Influencing Factors on the Knowledge-Transfer Channel of the Korean Academics Engaged in Science and Engineering (한국 이공계 대학교수 지식이전 경로의 영향요인)

  • Kwon, Ki-Seok;Park, Mun-Su
    • Journal of Information Technology and Architecture
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    • v.9 no.3
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    • pp.287-301
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    • 2012
  • Against Nonaka's seminal work in 1999, this study aims to investigate various influencing factors on knowledge-transfer channels of Korean academics. To do this, we surveyed 20,000 Korean academics in science and engineering with regard to factors involved in their formal and informal collaborative activities with firms. In particular, we focus on the individual characteristics of the academics when the channels are changed from informal channels (e.g. consulting) to formal channels (e.g. licensing), as the codification of knowledge is important when it is spilled over. According to the results, male academics with a longer career and in the field of applied disciplines in a big laboratories are likely to join the transformation of the channels. Interestingly, application capacity as measured by the number of patent application is significantly and positively related to the participation of formal channels. In contrast, scientific capacity as measured by the number of papers is significantly and negatively, or in some case weakly, related to the participation. Finally, based on the findings, some policy implications are put forwarded.

ICT Trend Analysis Based on Research Papers and Patents (논문 및 특허 기반의 ICT 동향 분석 연구)

  • Son, Yeonbin;Kim, Solha;Choi, Yerim
    • Journal of the Korea Convergence Society
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    • v.12 no.12
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    • pp.1-18
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    • 2021
  • ICT is the main driving force of Korea's economic growth. Korea has the world's best ICT competitiveness, and several policies are being implemented to maintain it. However, for successful policy implementation, it is crucial to understand ICT trends accurately. Therefore, this study analyzes the trends of 18 core technologies in the ICT field. In particular, the degree of scientific development and commercialization by technology are investigated through research paper analysis and patent analysis, respectively. Then, the trends shown by document type are compared based on the two analysis results. As a result, artificial intelligence and virtual reality are at the stage where commercialization is actively taking place after scientific development, and at the same time, since research is being conducted, it is expected to develop continuously. On the other hand, quantum computer and implantable device are in the basic research stage. It is necessary to understand the current research status and determine the direction of future support. The results of the ICT trend analysis conducted in this study can be used as a criterion for determining the future direction of Korean policy.

Data-Driven Technology Portfolio Analysis for Commercialization of Public R&D Outcomes: Case Study of Big Data and Artificial Intelligence Fields (공공연구성과 실용화를 위한 데이터 기반의 기술 포트폴리오 분석: 빅데이터 및 인공지능 분야를 중심으로)

  • Eunji Jeon;Chae Won Lee;Jea-Tek Ryu
    • The Journal of Bigdata
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    • v.6 no.2
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    • pp.71-84
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    • 2021
  • Since small and medium-sized enterprises fell short of the securement of technological competitiveness in the field of big data and artificial intelligence (AI) field-core technologies of the Fourth Industrial Revolution, it is important to strengthen the competitiveness of the overall industry through technology commercialization. In this study, we aimed to propose a priority related to technology transfer and commercialization for practical use of public research results. We utilized public research performance information, improving missing values of 6T classification by deep learning model with an ensemble method. Then, we conducted topic modeling to derive the converging fields of big data and AI. We classified the technology fields into four different segments in the technology portfolio based on technology activity and technology efficiency, estimating the potential of technology commercialization for those fields. We proposed a priority of technology commercialization for 10 detailed technology fields that require long-term investment. Through systematic analysis, active utilization of technology, and efficient technology transfer and commercialization can be promoted.

A Study on the Real Condition and the Improvement Directions for the Protection of Industrial Technology (산업기술 보호 관리실태 및 발전방안에 관한 연구)

  • Chung, Tae-Hwang;Chang, Hang-Bae
    • Korean Security Journal
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    • no.24
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    • pp.147-170
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    • 2010
  • This study is to present a improvement directions for the protection of industrial key technology. For the purpose of the study, the survey was carried out on the administrative security activity of 68 enterprises including Large companies, small-midium companies and public corporations. survey result on the 10 items of security policy, 10 items of personal management and 7 items of the assets management are as follows; First, stable foundation for the efficient implement of security policy is needed. Carrying a security policy into practice and continuous upgrade should be fulfilled with drawing-up of the policy. Also for the vitalization of security activity, arrangement of security organization and security manager are needed with mutual assistance in the company. Periodic security inspection should be practiced for the improvement of security level and security understanding. Second, the increase of investment for security job is needed for security invigoration. Securing cooperation channel with professional security facility such as National Intelligence Service, Korea internet & security agency, Information security consulting company, security research institute is needed, also security outsourcing could be considered as the method of above investment. Especially small-midium company is very vulnerable compared with Large company and public corporation in security management, so increase of government's budget for security support system is necessary. Third, human resource management is important, because the main cause of leak of confidential information is person. Regular education rate for new employee and staff members is relatively high, but the vitalization of security oath for staff members and the third party who access to key technology is necessary. Also access right to key information should be changed whenever access right changes. Reinforcement of management of resigned person such as security oath, the elimination of access right to key information and the deletion of account. is needed. Forth, the control and management of important asset including patent and design should be tightened. Classification of importance of asset and periodic inspection are necessary with the effects evaluation of leak of asset.

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Study on 3D Printer Suitable for Character Merchandise Production Training (캐릭터 상품 제작 교육에 적합한 3D프린터 연구)

  • Kwon, Dong-Hyun
    • Cartoon and Animation Studies
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    • s.41
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    • pp.455-486
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    • 2015
  • The 3D printing technology, which started from the patent registration in 1986, was a technology that did not attract attention other than from some companies, due to the lack of awareness at the time. However, today, as expiring patents are appearing after the passage of 20 years, the price of 3D printers have decreased to the level of allowing purchase by individuals and the technology is attracting attention from industries, in addition to the general public, such as by naturally accepting 3D and to share 3D data, based on the generalization of online information exchange and improvement of computer performance. The production capability of 3D printers, which is based on digital data enabling digital transmission and revision and supplementation or production manufacturing not requiring molding, may provide a groundbreaking change to the process of manufacturing, and may attain the same effect in the character merchandise sector. Using a 3D printer is becoming a necessity in various figure merchandise productions which are in the forefront of the kidult culture that is recently gaining attention, and when predicting the demand by the industrial sites related to such character merchandise and when considering the more inexpensive price due to the expiration of patents and sharing of technology, expanding opportunities and sectors of employment and cultivating manpower that are able to engage in further creative work seems as a must, by introducing education courses cultivating manpower that can utilize 3D printers at the education field. However, there are limits in the information that can be obtained when seeking to introduce 3D printers in school education. Because the press or information media only mentions general information, such as the growth of the industrial size or prosperous future value of 3D printers, the research level of the academic world also remains at the level of organizing contents in an introductory level, such as by analyzing data on industrial size, analyzing the applicable scope in the industry, or introducing the printing technology. Such lack of information gives rise to problems at the education site. There would be no choice but to incur temporal and opportunity expenses, since the technology would only be able to be used after going through trials and errors, by first introducing the technology without examining the actual information, such as through comparing the strengths and weaknesses. In particular, if an expensive equipment introduced does not suit the features of school education, the loss costs would be significant. This research targeted general users without a technology-related basis, instead of specialists. By comparing the strengths and weaknesses and analyzing the problems and matters requiring notice upon use, pursuant to the representative technologies, instead of merely introducing the 3D printer technology as had been done previously, this research sought to explain the types of features that a 3D printer should have, in particular, when required in education relating to the development of figure merchandise as an optional cultural contents at cartoon-related departments, and sought to provide information that can be of practical help when seeking to provide education using 3D printers in the future. In the main body, the technologies were explained by making a classification based on a new perspective, such as the buttress method, types of materials, two-dimensional printing method, and three-dimensional printing method. The reason for selecting such different classification method was to easily allow mutual comparison of the practical problems upon use. In conclusion, the most suitable 3D printer was selected as the printer in the FDM method, which is comparatively cheap and requires low repair and maintenance cost and low materials expenses, although rather insufficient in the quality of outputs, and a recommendation was made, in addition, to select an entity that is supportive in providing technical support.

Some General Characteristics of the Abstracting Journals Published in Korea (한국초록집의 특성)

  • 최성진
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.7 no.1
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    • pp.5-22
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    • 1994
  • This paper attempts to define some general characteristics of the Abstracting Journals published in Korea as evidenced in those published during last ten years. This purpose is achieved by comparing the results of the two studies conducted by the author in 1984 and in 1994. Both studies were conducted to present the state of the art in the abstracting services in Korea. The major conclusions made in this paper are summarised as follows: (1) Researchers and professionals working in a small number of subject fields are benefited by the abstracting journals, which provide current-awareness services of recent achievements in research and development in Korea. Those in most of the fields have no abstracting journals of their own, and naturally they have no substantial abstract-ing services. Even many researchers and professionals in the fields that have some abstracting journals are not informed of research results in their fields because the abstracting journals are scattered in many narrow subjects and in many cases, the abstracting journals only cover publications in some specific forms and kinds. (2) Abstracting journals that cover more than two subject fields, which are supposed to be of more or less help to the researchers and professionals in the subject fields that have no abstracting journals published in their fields, have rapidly increased in number in the past ten years. Most of suh abstracting journals carry thesis and dissertation abstracts, and the rest, those of research papers published in specific places, in specific forms, by specific institutions, and of reports of research projects sponsored by specific foundations. These abstracting journals are not of the kind that comprehensively provide researchers in related fields with current awareness of publications of research results in Korea. (3) Most of the abstracting Journals existing in Korea are Published by institutions of higher education and research institutes, and the rest, by commercial publishers, industrial firms, libraries, information centres, government agencies, research foundations, learned societies, etc. Those which publish many titles are small in number and those publish one or two titles are large in number. The former is largely made up of institutions of higher education and research institutes. (4) The abstracting journals published in Korea are classified by type into those of dissertations, research papers, journal articles, patent specifications in that descending order. The fact that Master; and doctoral dissertation abstracts ate dominating in Korea is due to the irrational practice of publishing those abstracts at many different institutions. (5) Most of the abstracting journals existing in Korea are published by national or government-supported research institutes in order to publicise their own research outputs. Their coverage of literature is normally narrow, and naturally their value to users is limited. (6) Korean is the desirable language for the abstracting journals intended to be distributed within Korea. About half of the abstracting jornals published in Korea is printed in Korean and the other half, in foreign languages, and in Korean and in foreign languages together. All the abstracting journals in foreign languages are printed in English except one, which is printed in Japanese. (7) Some twenty per cent of the abstracting journals in Korea is published monthly, bimonthly, and quarterly. The others are published annually, biannually and irregularly. The latter may not function properly as a current-awareness tool due to long intervals between their issues. It is particularly undesirable that about half of the abstracting journals in Korea is published irregularly. Most of the abstracting journals published in Korea are distributed freely to individuals and institutions selected by the publishers. (8) The abstracting journals published by the use of computers increased drastically in the past ten years. The abstracting journals produced by the conventional type-setting method will possibly disappear in Korea in another ten years to come. Automation of the production of abstracting journals does not simply mean technical, economic improvement in publishing processes but availability of machine-readable databases that can be used for many other pur-poses, including generation of other bibliographical publications and provision of machine literature searching capabilities. Necessary steps should be taken for this important development immediately.

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Abstracting Services in Korea (한국의 초록서비스에 대하여)

  • Choi Sung-Jin
    • Journal of the Korean Society for Library and Information Science
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    • v.24
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    • pp.9-51
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    • 1993
  • The purpose of this study is twofold: to investigate into general characteristics of the abstracting services in Korea and to discuss general directions of development of the abstracting services in the country. This study is designed to achieve the purpose by gathering and analysing data related to the abstracting journals published in the past ten years and by comparing the results with similar data gathered by the investigator in 1984. The major conclusions made in this study is summarised as follows. (1) Researchers and professionals working in limited numbers of subject fields are benefited by abstracting services of recent achievements in research and development in Korea. Those in most of the fields have essentially no abstracting services of such achievements. Even many researchers and professionals in the limited numbers of the fields that have some elementary abstracting services are not informed of research results in their fields because the abstracting journals are scattered in many narrow subjects and in many cases, the abstracting journals only cover publications in some specific forms and kinds. (2) Abstracting journals of general subjects, which are supposed to be of more or less help to the researchers in the subject fields that have no abstracting journals of their own, have rapidly increased in number in the past ten years. Most of such abstracting journals carry thesis and dissertation abstracts, and the rest those of research papers published in specific places, in specific forms, by specific institutes, and of reports of research projects sponsored by specific foundations. These abstracting journals are not of the kind that comprehensively provide general readers with current awareness of publications of research results in Korea. (3) Most of the abstracting journals existing in Korea are published by institutions of higher education and research institutes, and the rest by commercial publishers, industrial firms, libraries, information centers, government agencies, research foundations, learned societies, etc. Those which publish many titles are small in number and those publish one or two titles are large in number. The former is largely made up of institutions of higher education and research institutes. (4) Ten years ago, there was not a single publishing house that produced abstracting journals. Three commercial publishing houses now produce abstracting journals. As this change occurs, centers of excellence are founded and competitive elements are introduced in abstracting services. This change, in turn, is expected to improve quality of the other abstracting journals in Korea. (5) The abstracting journals published in Korea are classified by type into those of dissertations, research papers, journal articles, patent specifications in that descending order. The fact that Master's and doctoral dissertation abstracts are dominating in Korea is due to the irrational practice of publishing those abstracts at many institutions. (6) Most of the abstracting journals existing in Korea are published by national or government-supported research institutes in order to publicise their own research outputs. Their coverage of literature is normally narrow, and naturally their value to users is limited. (7) The abstracting journals published in Korea increased in number at the rate of $77.8-100\%$ every five years in the past twenty-five years. Most of the abstracting journals that ceased to be published during the period survived for two years. (8) Korean is the desirable language for the abstracting journals designed to be distributed within Korea. About half of the abstracting journals published in Korea is printed in Korean and the other half in foreign languages, and in Korean with foreign languages. All the abstracting journals in foreign languages are printed in English xcept one, which is printed in Japanese. (9) Some twenty percent of the abstracting journals in Korea is published monthly, bimonthly, and quarterly. Others are published annually, biannually, and irregularly. The latter may not function properly as a current-awareness tool due to long intervals between their issues. It is particularly undesirable that about half of the abstracting journals in Korea is published irregularly. Most of the abstracting journals published in Korea are distributed freely to individuals and institutions selected by the publishers. (10) The abstracting journals published by the use of computers increased drastically in the past ten years. The abstracting journals produced by the conventional type-setting method will probably disappear In Korea in another ten years to come. Automation of the production of abstracting journals does not simply mean technical, economic improvement of publishing processes but availability of machine-readable databases that can be used for other purposes, including the generation of other publications and the provision of machine literature searching capabilities. Necessary steps should be taken for this important development that is occurring in the abstracting services in Korea.

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Quality Changes in Brined Baechu Cabbage using Different Types of Polyethylene Film, and Salt Content during Storage (절임배추 저장 중 폴리에틸렌 포장필름 종류와 소금 절임 농도에 따른 품질변화)

  • Kim, Young-Wook;Jung, Ji-Kang;Cho, Young-Jin;Lee, Sun-Jin;Kim, So-Hee;Park, Kun-Young;Kang, Soon-Ah
    • Food Science and Preservation
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    • v.16 no.5
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    • pp.605-611
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    • 2009
  • Korean Baechu cabbage(known as Chinese cabbage) brined in 0%, 5% and 10% (all w/v) salt solutions were packed using high-density polyethylene film (HDPE-film), low-density polyethylene film (LDPE-film), or Mirafresh film (MF-film, US patent No. 5972815), and stored at 4C for 4 weeks. Changes in pH and salinity, and microorganism counts (lactic acid bacteria and total bacteria), were investigated. There was no significant difference in the pH change in cabbage stored using various films when the vegetables were not salted. However, the pH was most stable in Baechu cabbage prepared using 10% salt solution. Cabbage treated with 0%, 5%, and 10% salt showed salinity values of 0.83%, 1.17% and 1.62%(all w/w), respectively, after 4 weeks of storage by LDPE-film. When cabbage was treated with the highest concentration of salt solution, the count of lactic acid bacteria increased but that of total bacteria decreased. The pH from pH 6.10 to pH 4.32, pH 5.68, and pH 5.92 in brined cabbage packed in HDPE-film, LDPE-film, and MF-film, respectively, after 4 weeks. When MF-film was used, the pH showed the greatest stability of all films tested, regardless of the concentration of salt solution employed in brining. The counts of lactic acid bacteria and total bacteria increased by all tested films during storage. Cabbage packed by MF-film showed the lowest increase in bacterial counts. In conclusion, MF-film was found to be the most effective packaging material for Baechu cabbage and brining in 10% salt solution was optimal to enhance the shelf life of the vegetable. LDPE-film was more effective than was HDPE-film for storage of brined cabbage.

Problems of the Current Referral System of the Terminal Cancer Patients in Korea (말기 암 환자의 완화 의료 연계 시스템의 문제점과 개선 방안)

  • Yun, Cho-Hee;Lee, Ju-Young;Kim, Mi-Ra;Heo, Dae-Seok
    • Journal of Hospice and Palliative Care
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    • v.5 no.2
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    • pp.94-100
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    • 2002
  • Purpose : The system to refer terminally ill patients to palliative or hospice care which ultimately give them emotional, psychological, and social support hasn't been fully developed and organized yet in Korea. The controversies concerning the current referral system are being analyzed to present the improvements. Methods : The questionnaires were asked to be filled out by family members of the 76 patients by phone interview, who were referred from the Seoul National University Hospital between April, 2001 to March, 2002. They were referred to the 35 palliative and hospice care-giving institutes and hospitals which were given questionnaires by mail. Results : Of the 76 patient's family members, 47 family members accepted to answer the questionnaire. The first thing that influence to family to determine the referral of patient was solicitation of doctors or nurses (44%). And they were influenced by allowance for the other things such as convenience of patients (32%), convenience of caring family members (24%). In the course of determining of referred institutes, responders had considered at first their dwelling area, and then fame of institutes, the place which patent had wanted to spend last hours or which is suitable for patient's funeral service, and their financial condition. Thirty-eight the 47 responders answered that they had experienced difficulties in referral procedure. The worst among difficulties was unwanted discharge, and followings were lack of information about the referred institutes, concern about patient's suffering, resistance of patient and opposition of other family members, etc. Although they expressed dissatisfaction in referral procedure, most of them answered they had been satisfied with hospice care at referred institute after referral. Merits of referral which responders counted were patient's peace, caring family's comfort and reduced cost in order. Of the 35 referred institutes, 24 institutes' staffs responded mail questionnaires and sent to us in return. Except one responder, the rest approved the referral system and thought that referred patients had been satisfied with their hospice care. And they claimed that systemic support of the government is definitely necessary. The most difficult thing which responders experienced in care of referred patients was lack of information about patients. Besides, there were patient's financial problems, lack of understanding about their institutes of patients or family, and inconvenience of terminal cancer patient's pain control. Conclusion : The development and support of the organized referral system is needed to alleviate the troubles which patients, family members, and palliative or hospice institutes and hospitals have to face through the procedure of the referral.

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