• Korean Journal of Veterinary Service
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• v.25 no.3
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• pp.315-330
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• 2002

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2003.10a
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• pp.44-44
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• 2003

Canine distemper virus (CDV) is a member of the genus Morbillivirus and the family Paramyxoviridae [3]. CDV is known to induce immunosuppression in affected animals by disrupting both humoral and cellular immunity [3]. This often results in secondary opportunistic infections. Activated toxoplasmosis develops in dogs whose immune systems have been damaged by CDV [3]. (omitted)

• Clinical and Experimental Pediatrics
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• v.53 no.5
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• pp.623-628
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• 2010

The mumps virus is a single-stranded, non-segmented, negative-sense RNA virus belonging to the $Paramyxoviridae$ family. Mumps is characterized by bilateral or unilateral swelling of the parotid gland. Aseptic meningitis is a common complication, and orchitis is also common in adolescents and adult men. Diagnosis is based on clinical findings, but because of high vaccination coverage, clinical findings alone are not sufficient for diagnosis, and laboratory confirmation is needed. Mumps is preventable by vaccination, but despite high vaccination coverage, epidemics occur in several countries, including Korea. Many hypotheses are suggested for these phenomena. In this review, we investigate the reason for the epidemics, optimal methods of diagnosis, and surveillance of immunization status for the prevention of future epidemics.

• Korean Journal of Veterinary Service
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• v.25 no.2
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• pp.153-174
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• 2002

파라믹소바이러스과 (Parnxouiridae) 바이러스는 외피당단백질의 생물학적 특성에 있어서 Orthomyxoviridae와, 분절되지 않은(nonseg-mented)게놈과 그 발현의 구성 측면에서 Rhbdoviridae와 유사성을 갖는 바이러스로서 외피로 둘러 싸여 있는 마이너스쇄(negative strand) RNA 바이러스이다. 마이너스쇄 RNA 바이러스의 게놈 RNA는 2가지 기능으로 작용한 다. 즉, 첫째는 mRNA 합성을 위한 주형(鑄型, template)으로 작용하고, 둘째는 플러스쇄 (anti-genome(+) strand)의 합성을 위한 주형으로서 작용한다. 마이너스쇄 RNA바이러스는 그들 자신의 RNA전사효소를 코드화 하여 저장하지만, mRNA는 감염세포 내에서 게놈이 노출된 후에만 합성된다. 바이러스 복제는 mRNA의 합성후 일어나며 연속된 바이러스단백질의 합성을 필요로 한다. 새로 합성된 플러스쇄(antigenome(+)strand)는 마이너스쇄 게놈 RNA의 복제를 도모하기 위한 주형(鑄型)으로서 작용한다.

• Journal of Veterinary Science
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• v.25 no.1
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• pp.3.1-3.20
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• 2024

The Newcastle disease virus (NDV) outbreak was first reported in Java Island, Indonesia, in 1926, which was then reported further in Newcastle-upon-Tyne, England. Nevertheless, the NDV is still endemic in Indonesia, with outbreaks occurring in free-range and commercial chicken farms. The dynamic evolution of the NDV has led to the further development of vaccines and diagnostic tools for more effective control of this virus. This paper discusses the history of the NDV occurrence, vaccines, the development of diagnostic tools, and the epidemiological condition of the NDV in Indonesia. Indonesia, which has the largest poultry population in the world after China, has challenges in preventing and controlling this virus that causes economic losses to the farmers and has an impact on the welfare of the poultry farming community in Indonesia.

• Childhood Kidney Diseases
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• v.21 no.2
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• pp.89-93
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• 2017

Purpose: Virus-associated rhabdomyolysis is very rare. We report 15 patients with rhabdomyolysis caused by various viruses. Methods: Fifteen patients who were diagnosed with rhabdomyolysis and a viral infection were included in this study. Clinical, laboratory, and radiologic findings were evaluated through retrospective chart reviews. Results: Chief complaints were severe bilateral lower leg pain and leg weakness. The median age was 5.7 years. The male:female ratio was 2:5. The viral infections were caused by influenza virus B, parainfluenza virus, and rhinovirus. One patient with influenza virus B had coinfection with coronavirus. Median initial laboratory values and ranges were as follows: serum creatinine, 0.4 (0.1-0.5) mg/dL; serum aspartate transaminase, 124 (48-1,098) IU/L; serum alanine transaminase, 30 (16- 1,455) IU/L; serum creatine kinase, 2,965 (672-16,594) IU; serum lactate dehydrogenase, 400 (269-7,394) IU/L; serum myoglobin, 644 (314-3,867) ng/mL; urine myoglobin, 3 (3-10,431) ng/mL. All patients recovered without complications. Conclusion: This is the first report of the simultaneous occurrence of rhabdomyolysis caused by various viruses. This is also the first report of rhinovirus-associated rhabdomyolysis.

• Korean Journal of Veterinary Research
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• v.46 no.4
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• pp.371-379
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• 2006

Newcastle disease virus (NDV) is a single-stranded negative sense RNA virus, which has been classified as a member of the Avulavirus genus of the Paramyxoviridae family. It is also one of the most important pathogens in the poultry industry. The glycoproteins, fusion (F) and hemagglutinin-neuraminidase (HN), determine the virulence of NDV, and the relevant molecular structures have already been determined. NDV isolates differ in terms of virulence, and at least 2 of 9 genotypes (I-IX) have been shown to co-circulate. Therefore, it is clearly important to differentiate between vaccine strains and field isolates. In vivo pathogenicity tests have been the standard protocol for some time, but molecular methods appear preferable in terms of the rapidity of diagnosis, as well as animal welfare concerns. In this study, we have designed primer sets from HN gene for phylogenetic analysis and restriction enzyme analysis, and from F gene for pathotype-specific RT-PCR. Via the combination of 2 methods, 106 Korean NDV isolates obtained from 1980 to 2005 were differentiated into vaccine strains, and virulent genotypes VI and VII. The genotype VI viruses were only rarely isolated after 1999, and genotype VII, after it was initially isolated from poultry in 1995, recurred in 2000, and then became the main NDV constituting a threat to the Korean poultry industry.