• 제목/요약/키워드: paralysis

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An atypical phenotype of hypokalemic periodic paralysis caused by a mutation in the sodium channel gene $SCN4A$

  • Park, Yang-Hee;Kim, June-Bum
    • Clinical and Experimental Pediatrics
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    • v.53 no.10
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    • pp.909-912
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    • 2010
  • Familial hypokalemic periodic paralysis is an autosomal-dominant channelopathy characterized by episodic muscle weakness with hypokalemia. The respiratory and cardiac muscles typically remain unaffected, but we report an atypical case of a family with hypokalemic periodic paralysis in which the affected members presented with frequent respiratory insufficiency during severe attacks. Molecular analysis revealed a heterozygous c.664 C>T transition in the sodium channel gene $SCN4A$, leading to an Arg222Trp mutation in the channel protein. The patients described here presented unusual clinical characteristics that included a severe respiratory phenotype, an incomplete penetrance in female carriers, and a different response to medications.

Isolated Vagus Nerve Involvement of Herpes Infection with Delayed Vocal Fold Paralysis (지연성 성대 마비를 동반한 미주신경에 국한된 Herpes 감염)

  • Kwon, Tack-Kyun
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.16 no.1
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    • pp.81-84
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    • 2005
  • Vagus nerve palsy caused by herpes virus infection is rare. Here, the author presents a 65-year-old woman with acute onset of right side otalgia and sore throat, followed by delayed vocal fold paralysis on the same side. Vesicles were also found on the posterior wall of ear canal but the tympanic membrane was not involved. Laryngoscopy revealed multiple ulcerative lesions on the pharyngeal and laryngeal mucosa exclusively on the right side. One month later, she noticed dyshonia which turned out right vocal fold paralysis. Skull base to upper chest CT did not reveal local lesion. Three months after finishing the acyclovir, her symptoms were almost gone and vocal fold movement has almost completely improved. Vagus nerve involvement of herpes infection should be considered as a differential diagnosis for patients with herpes zoster oticus with sore throat.

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Clinical Research of Korean Medical Treatment for the Peripheral Facial Paralysis (안면신경마비의 치료와 관련된 한의학 보고들에 대한 고찰)

  • Sim, Sung-Yong
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.28 no.4
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    • pp.62-73
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    • 2015
  • Objectives : The aim of this study is to propose the treatment of Peripheral Facial paralysis using Korean medical treatment methods as acupuncture, Phmacopuncture, medicine and etc.Methods : Papers were searched in internet sites such as Nation Digital Science Library, Koreanstudies Information Service System, Research Information Sharing Service and The National Assembly Library with title and abstract ʻBellʼs palsyʼ or ʻFacial paralysisʼ and ʻphamacopunctureʼ or ʻbee venomʼ orʻhominis placentaʼetc.Results : 18 papers using phamacopuncture were selected. Most of all is used Bee Vemon Phamcopuncure and all of them used Acupuncture and Medicine therapies. And Groups used Phamacopuncture such as ʻBee Venomʼ,ʻHominis Placentaʼ, ʻSoyeomʼ, ʻBUMʼ,ʻJungsongoulhyulʼetc are statistically improved compared to unused Groups.Conclusions : Acupuncture and Phamacopuncture are useful methods to improve the Peripheral Facial Paralysis, but further researchs are needed.

Analysis of Relations Between Physiologic Parameters and Pulse Transit Time on the Ultrasound Therapy (초음파 재활치료 시 PTT와 생리변수의 상관관계 분석)

  • Kim, Sung-Min;Choi, Sang-Hyuk;Lee, Man-Pyo;Choi, Byeong-Cheol;Jung, Whoi-Seong;Park, Sung-Yoon
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.8
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    • pp.1514-1520
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    • 2007
  • Currently, the signal of the human body is measured with various methods, and a noninvasive investigation of various methods is useful diagnosis method. PTT(Pulse Transit Time) which is noninvasive investigation make use of to estimate the physiological phenomena. PTT has a latent information of cardiovascular system. So we have the experiments for analysis of the relations between PTT and physiological parameters. We examine to correlate to the physiological parameters, an age and degree of paralysis on the ultrasound therapy. The 40 patients who has a such paralysis join our experiment, and we obtain the PTT data that normal condition and states after ultrasound therapy. We study that PTT after the ultrasound therapy for patients who have a paralysis was related to an age and degree of paralysis.

A Clinical Study on Strabismus Patient of Abducence Nerve Paralysis in Soyangin Improved with Yangkyuksanhwa-tang (양격산화탕(凉隔散火湯)으로 호전(好轉)된 소양인(少陽人) 외전신경마비(外轉神經痲痺) 사시환자(斜視患者) 치험 1례)

  • Choi, Ae-Ryun;Ha, Jin-Ho;Lee, Jung-Hwan;Jang, Woo-Seok;Goo, Deok-Mo
    • Journal of Sasang Constitutional Medicine
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    • v.20 no.3
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    • pp.176-183
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    • 2008
  • 1. Objectives The purpose of this case study is to evaluate the effects of Yangkyuksanhwa-tang which is based on Sasang Constitutional Medicine for strabismus of abducence nerve paralysis. 2. Methods This patient was created by Soyangin's Constitutional Medications according to the result of Sasang Constitutional diagnosis. We evaluated the abduction deficit that described how to use Scott and kraft. 3. Results & Conclusions This case study shows an efficient result of using Yangkyuksanhwa-tang in treatment of Strabismus of abducence nerve paralysis.

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A Case of Voice Therapy for Post-Thyroidectomy Syndrome (갑상선 수술 후 양측성 성대마비 환자의 음성치료 1예)

  • Kang, Young Ae;Song, Kun Ho
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.33 no.1
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    • pp.45-49
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    • 2022
  • Post-thyroidectomy syndrome refers to various voice changes experienced after the thyroid surgery. Among them, surgery or injection therapy has been prioritized over voice therapy for the bilateral vocal cord paralysis. However, if it is possible to determine whether voice therapy can be applied first, a faster treatment recovery will be possible. In this study, voice therapy was performed on a 59-year-old female patient with bilateral vocal cord paralysis after total thyroidectomy. This study is to presents the criteria for applying the voice therapy first for bilateral vocal folds paralysis and to share successful voice therapy sessions.

Laryngeal Framework Surgery for Unilateral Vocal Fold Paralysis (일측성 성대마비 환자에서의 후두골격수술)

  • Cha, Heung Eog;Woo, Joo Hyun
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.33 no.2
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    • pp.59-63
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    • 2022
  • The laryngeal framework surgery (LFS) is an operation to correct the position and tension of the vocal cords by changing the laryngeal cartilage and muscles. LFS such as type 1 thyroplasty, arytenoid adduction, and arytenopexy is performed to improve the voice of patients with unilateral vocal cord paralysis. It is known that the voice improvement effect of LFS in patients with unilateral vocal cord paralysis is excellent and lasts for a long time. LFS can also be operated under local anesthesia. Complications are not common, however, severe complications like airway obstruction could occur after the operation. Recently, several other attempts to modify the traditional surgical method have been reported. This review is intended to be helpful in understanding the characteristics and changes in laryngeal framework surgery.

Clinical Observation of Effect on Severity of Symptoms and Safety of Auto-microneedle Therapy in Patients with Peripheral Facial Paralysis (자동 미세침이 말초성 안면마비 환자의 증상 정도 및 안전성에 미치는 영향에 대한 임상 관찰)

  • Lee, Ung-In;Kwon, You-Jung;Kim, Hyun-Ho;Yoo, Je-Hyuk;Kim, Kyung-Wook;Kang, Jung-Won;Lee, Sang-Hoon
    • Journal of Acupuncture Research
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    • v.29 no.4
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    • pp.35-42
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    • 2012
  • Objectives : This study was to observe clinical application of auto-microneedle therapy system (AMTS) in patients with peripheral facial paralysis. Methods : 27 peripheral facial paralysis patients were observed after taking AMTS at Facial Palsy Center, Kyung Hee University Oriental Medicine Hospital from March 1, 2011 to January 9, 2012. We assessed the symptoms of facial paralysis with Yanagihara unweighted grading system, Sunnybrook facial grading system(SBGS) and facial disability index(FDI), and observed adverse events and total safety of the treatment. Results : The scores of facial palsy scales increased after AMTS in Yanagihara grading system and Sunnybrook facial grading system. AMTS-related adverse events were mild pain(5.9%) and fatigue(3.5%), which needed no extra treatment. The total safety evaluation was between 'safe' and 'nearly safe' level. There were no other serious adverse events. In addition, patients were satisfied with subjective improvement including facial tingling and numbness. Conclusions : AMTS can be applied as an adjunctive treatment for patients with peripheral facial paralysis due to its safety and clinical usefulness. It is easier to stimulate wide skin area in a short time. Further clinical research is required to investigate the effectiveness of ATMS in a more rigorous RCTs.

The Effect of Voice Therapy in Unilateral Vocal Fold Paralysis (일측성 성대마비 환자의 음성치료 효과)

  • Lee, Chang-Yoon;An, Soo-Youn;Chang, Hyun;Son, Hee Young
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.27 no.1
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    • pp.45-50
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    • 2016
  • Background and Objectives : This study aims to conduct post-voice therapy to patients with unilateral vocal fold paralysis for vocal improvement, motility recovery and analyze the results. Materials and Methods : Voice therapy was conducted to 13 patients who had shown response to voice therapy amongst 98 patients diagnosed with unilateral vocal fold paralysis. In order to be able compare before and after perceptual, acoustic and aerodynamic evaluations were conducted after voice therapy. Also, by using dysphagia checklist, we have verified whether if the patient had dysphagia prior to voice therapy. The therapy was conducted by improving the larynx movement and glottal contact, whilst removing hypertension of the supraglottic. Results : All 13 patients who underwent voice therapy had shown improvements that are statistically significant from 4 scales excluding the S scale from auditory perception evaluation (p<0.05), with enhanced glottal contact. In acoustic evaluation, Jitter, Shimmer and NHR had shown significant improvement after voice therapy. MPT was also notably improved among aerodynamical evaluation (p<0.001). All 11 patients had with dysphagia prior to voice therapy reported to have improved swallowing functions. Conclusion : Application of adequate voice therapy to patients with unilateral vocal fold paralysis, is an effective method that might be employed in the initial phase. Especially, the voice therapy proposed in this study is expected to be useful for patients in hypertension status due to secondary compensation after initial paralysis, since it focuses on improving vocal symptoms in a calm state with the supraglottis sufficiently relaxed. Also, the therapy is expected to be effective for improving swallowing functions.

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The Clinical Study for Peripheral Facial Paralysis Treated with Herbal Stream Therapy (구안와사에 대한 훈증요법 복합치료 효과)

  • Kim, Ji-Soo;Park, Soo-Yeon;Choi, Chang-Won;Kim, Kyeong-Soo;Kim, Kyeong-Ok;Wei, Tung-Shuen;Yang, Seung-Joung
    • Herbal Formula Science
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    • v.23 no.1
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    • pp.151-159
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    • 2015
  • Objectives : This study was performed to investigate the effect of herbal steam therapy on peripheral facial paralysis. Methods : 55 patients with peripheral facial paralysis were treated with Korean Medicine therapy including herbal steam therapy. We evaluated the effect of Korean Medicine therapy including herbal steam therapy by Yanagihara grading system. Results : 1. 55 patients were treated with Korean Medicine therapy and 23.27±14.11 times of herbal steam therapy. 2. After treatment, Y-system score was significantly increased(p-value<0.001) from 18.00±6.5514 to 35.00±6.3404. Conclusions : Herbal stream therapy seem to be effective to improve symptoms of peripheral facial paralysis. Further studies will be needed to identify the beneficial of herbal steam therapy on peripheral facial paralysis.