• 생물정신의학
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• 제11권1호
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• pp.3-13
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• 2004

Objectives:Functional magnetic resonance imaging(fMRI) is one of the most useful techniques for assessing localized changes in cerebral blood flow and oxygenation using diverse challenge paradigms. This review presents the results of fMRI studies relating to schizophrenia. Methods:Several fMRI articles on this subject in psychiatric journals were surveyed. Results:Even with some methodological limitations, most studies showed activity differences between schizophrenics and control subjects. Conclusion:fMRI extends our understanding of the pathophysiological basis of schizophrenia and offer an opportunity for the assessment and management of its pathology.

• Molecules and Cells
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• 제41권1호
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• pp.65-72
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• 2018

Autophagy is an evolutionally conserved cytoplasmic degradation system in which varieties of materials are sequestered by a double membrane structure, autophagosome, and delivered to the lysosomes for the degradation. Due to the wide varieties of targets, autophagic activity is essential for cellular homeostasis. Recent genetic evidence indicates that autophagy has a crucial role in the regulation of animal lifespan. Basal level of autophagic activity is elevated in many longevity paradigms and the activity is required for lifespan extension. In most cases, genes involved in autophagy and lysosomal function are induced by several transcription factors including HLH-30/TFEB, PHA-4/FOXA and MML-1/Mondo in long-lived animals. Pharmacological treatments have been shown to extend lifespan through activation of autophagy, indicating autophagy could be a potential and promising target to modulate animal lifespan. Here we summarize recent progress regarding the role of autophagy in lifespan regulation.

• Journal of Mechanical Science and Technology
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• 제15권8호
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• pp.1132-1142
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• 2001

The paper describes the construction of global function approximation models for use in design optimization via global search techniques such as genetic algorithms. Two different approximation methods referred to as evolutionary fuzzy modeling (EFM) and neuro-fuzzy modeling (NFM) are implemented in the context of global approximate optimization. EFM and NFM are based on soft computing paradigms utilizing fuzzy systems, neural networks and evolutionary computing techniques. Such approximation methods may have their promising characteristics in a case where the training data is not sufficiently provided or uncertain information may be included in design process. Fuzzy inference system is the central system for of identifying the input/output relationship in both methods. The paper introduces the general procedures including fuzzy rule generation, membership function selection and inference process for EFM and NFM, and presents their generalization capabilities in terms of a number of fuzzy rules and training data with application to a three-bar truss optimization.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1995년도 Proceedings of the Korea Automation Control Conference, 10th (KACC); Seoul, Korea; 23-25 Oct. 1995
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• pp.39-42
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• 1995

A new methodology for representing the interaction between machines and the interlock signals required in FMCs has been developed. Object-Oriented Philosophies (OOPs) lend themselves to the development of such a scheme. A methodology developed here regards the tasks to be performed by the cell or any of its constituent machines for being primal. Sensory signals indicating the changes of state pf machines are used to trigger or initiate tasks. A task may be simple and require a relatively short time to execute, or may be complex and lengthy. This methodology may be depicated by a set of diagrams called Task Initiation Diagram (TID) and their accompanying rules.

• 전자공학회지
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• 제24권2호
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• pp.13-26
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• 1997

Throughout the world in major urban centers, the volume of vehicular traffic on roads continues to increase. ITS provides drivers with traffic information and new routing options on route In order to make them move quickly to their destinations. The higher mobility, the more productivity we gain. The ultimate goal of Intelligent Transport System is to improve mobility. ITS world is broad and quite varied, as demonstrated by ITS user services, their distinct needs, and complex Interactions and synergies. ITS ties the transportation and telecommunication worlds together. The complex world of telecommunications is evolving and expanding rapidly. Especially over the last two decades, the birth and unprecedented growth of wireless is really marvelous and further holds tremendous promise into the future. This wireless and emerging technologies will offer extensive opportunities to handle many ITS user services, and alter many of the traditional paradigms of transportation.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2005년도 춘계학술대회 논문집
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• pp.1138-1145
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• 2005

The public, mass transportation, monopoly, speediness and the long distance transportation of railway have realized by representative advantage from former days. But realization for railway that is declining by industry on the decline by the 1970s since the 1st World War has been changing recently newly. Development of a technology and fast change of industry environment exerted big effect about traffic. And IT and wave in 21C that is spoken for to environment changed together paradigm for railway. Now, is forecasted that period 'Renaissance of railway' may set on the near future because road embankment is getting into the spotlight again by the future alternative among transportation worldwide. In this paper, characteristic of railway to move altered how, and paradigms of been rising railway quality wish to examine what it is newly.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 춘계학술대회 논문집
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• pp.1276-1281
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• 2007

This study examined the procedures and legal issues for introduction and current Salary-structures and methods for system introductions centered around Seoul Metro which is railway related public company along with the background on introducing Salary-peak system and national/international situations according to the changes in paradigms. Base on these, the study deduced presented plans for improving corporate competitiveness by the introduction of Salary-peak system such as target for applications and ages for Salary-peak and the rate of fall, plans for adjusting duties to present optimum plans according to the introduction of Seoul Metro Salary-peak System.

• 공학교육연구
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• 제15권3호
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• pp.66-71
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• 2012

In this paper, we try to explore basic factors that defines easy-to-learn programming language and easy-to-learn development environments for novice students who have not been exposed to computer programming language education. For these purpose, we investigate and analyze computer programming languages that are widely used in industrial environments, and present the summary and analyzed results. From the experimental results, most novice programmers understand computer programming languages in terms of procedural programming languages rather than in terms of functional programming languages or object oriented programming languages. Furthermore, we have found that, for effective education of basic level programming languages, factors of development environments are much more important than factors of programming paradigms that the computer programming languages are based on.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1990년도 한국자동제어학술회의논문집(국내학술편); KOEX, Seoul; 26-27 Oct. 1990
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• pp.575-579
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• 1990

This paper describes an algorithm that can efficiently analyze the multichannel ECG signal using the frame. The input is a set of significant features (points) which have been extracted from an original sampled signal by using the split-and-merge algorithm. A signal from each channel can be hierarchical ADN/OR graph on the basis of the priori knowledge for ECG signal. The search mechanisms with some heuristics and the mixed paradigms of data-driven hypothesis formation are used as the major control mechanisms. The mutual relations among features are also considered by evaluating a score based on the relational spectrum. For recognition of morphologies corresponding to OR nodes, an hypothesis modification strategy is used. Other techniques such as instance, priority update of prototypes, and template matching facility are also used. This algorithm exactly recognized the primary points and supporting points from the multichannel ECG signals.

• 한국실내디자인학회논문집
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• 제20권4호
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• pp.155-162
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• 2011

In order to pursue the traces of truth, boundaries set by man for convenience were crossed or Integrated leading to the discovery of new paradigms. Such phenomena including collaboration, convergence, crossover and etc. are expressed in various forms across the society and culture. In particular, development of digital technology is moving away from its previous color based on scientific, statistical and quantitative perspective by using diverse variables. Also, as the borderlines of genres become increasingly more ambiguous, various concepts of color blending developed rapidly. Thus These chaosmos-like color blending have created new contents. This research aims to understand the principle of color blending in Karim Rashid's work, which advocates the world of design in diverse fields from industrial products to architecture. The principle of color blending such as information change, source color and destination color, interaction, and etc. makes it possible to extract the expressed element and method of color blending. Meanwhile, the features of color blending such as integrated space and time, vague form, and narrative genre can be inferred from case analysis.