• CELLMED
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• v.9 no.2
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• pp.1.1-1.4
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• 2019

Pruritic urticarial papules and plaque of pregnancy presents with difficulty in its management owing to the limited intervention options available during pregnancy and their sub optimal responses. In pregnancy, also often the mother remains reluctant in getting exposed to biological medicines for her concern to the growing fetus. In such conditions, Ayurveda, the traditional health care system from India is often looked as a safe alternative to offer symptom resolution and safe continuation of pregnancy without the discomforts of urticaria. This case report is an illustration in this regard.

• Korean Journal of Veterinary Research
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• v.53 no.4
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• pp.253-256
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• 2013

An 8-year-old, castrated male, Schnauzer dog was presented for evaluation of gradually worsening erythematous papules. Physical examination revealed multiple erythematous papules having a firm, gritty texture located in bilateral ears, dorsal midline, perianal and inguinal area. Skin biopsy revealed aberrant structure, characterized by atrophic epidermal-dermal layer structure with granular materials which was presumed as calcinosis cutis secondary to iatrognic hyperadrenocotricism. By initiating minocycline for 14 days, there was reduction in size, number of calcium deposit with remarkably decreased erythema. This case report presents the clinical trial of minocycline as a potential agent in treating dogs with calcinosis cutis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.1 s.32
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• pp.250-255
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• 2007

Molluscum contagiosum(MC) is a viral disorder of the skin and mucous membranes characterized by decrete single or multiple, flesh-colored papules. There was the 6 years old woman who suffered from umbilicated papules and pruritis of back. First, Her mother choiced western medicine, and was treatded with topical(ointment applicatoin) and surgical(curettage) method. Despite of western medical treatment during 3 months, there was not recovery of symptoms. So, she visited the Dept. of Opthalmology & Otorhinolaryngology & Dermatology, College of Oriental Medicine, Kyungwon University for oriental medical treatment. The oriental medical treatment reduced the symptoms of the patient remarkably during 8weeks. So we report the healing process and result of this patient in this study. There is few report that treat MC with oriental medical method. If more clinical trials like this are proved to be effective, we can expect that oriental medical treatment will be a good method in MC.

• Annals of dermatology
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• v.30 no.6
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• pp.731-732
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• 2018

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.2
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• pp.612-620
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• 2004

Acne is a relatively common disorder, especially in the adolescent or 20-30th young people. The condition is characterized by comedones, papules and pustules. Acne has social and psychological influence on the acne patients. But there is no perfect treatment of acne. It is known that Herba Houttuyniae has anti-inflammatory action and anti-bacterial action. Therefore, we studied the effect of 5% Herba Houttuyniae extract solution on the acne. The study was designed to compare the efficacy of 5% Herba Houttuyniae solution on the acne. The study was carried out on two groups-a experimental and a control group- for 4 weeks. Efficacy was determined by investigating counts of non-inflammatory open and closed comedones, and inflammatory papules and pustules once a week. After a experiment self-assessment was checked. As the result of the study, we found that a significant difference was observed in the mean counts and self-assessment of the experimental group. So we concluded that Herba Houttuyniae has a clinical effect on the acne.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.2
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• pp.186-196
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• 2020

Objectives : This study is to report a case of chronic allergic contact dermatitis, treated with Korean medicine, primarily focused on Oryeong-san. Methods : A 43-year-old female has suffered from dermatitis in axillary, lower abdominal, inguinal and popliteal area for more than 10 years. She was diagnosed with chronic allergic contact dermatitis accompanied by skin symptoms such as severe pruritus, erythema, skin pigmentation, papules and lichenification, and by decreased quality-of-life. She received Korean medicine treatment including herbal medicine, acupuncture and herbal external medication for 4 months. Results : The skin symptoms such as pruritus, erythema, skin pigmentation, papules and lichenification were remarkably improved. Also, the NRS of pruritus changed from 10 to under 1, and the DLQI score changed from 29 to 6. Conclusions : This case report suggests that Korean medicine, especially Oryeong-san may have a role in treating skin symptoms such as pruritus, erythema, skin pigmentation, papules and lichenification in the patients diagnosed with chronic allergic contact dermatitis. Also, the improvement of skin symptoms treated with Korean medicine may result in quality-of-life improvement in those patients.

• Korean Journal of Veterinary Research
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• v.39 no.5
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• pp.945-950
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• 1999

A 4-year-old female American cocker spaniel was hospitalized with 6 months prolonged dermal problems in The Veterinary Medical Teaching Hospital of Seoul National University. Initial noticed signs by owner of this dog were rashes and papules on ear part and they were spreaded whole body. On initial physical examinations, papules, pustules, crusts, and erythema were presented on whole body. Diameters of focal scaly and erythematous alopetic lesions were varied ranging 1 to 4cm. Skin scraping for detecting ectoparasites and wood's light examinations for dermatophyte were negative. Any bacteria were not detected but Malassezia pachydermatis was detected on cytological examination and fungal culture. The dog was treated with Itraconazole (5mg/kg, q12h) and Cephalexin (20mg/kg, q12h) orally and then bathed with 2% chlorhexidine shampoo twice per week for 5 weeks. From 12 weeks after starting therapy, all dermal problems were disappeared although some mild pyoderma were once relapsed. Regular chlorhexidine bathing treatment so far has been continued for preventing recurrence.

• Annals of dermatology
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• v.30 no.6
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• pp.716-720
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• 2018

Perforating granuloma annulare (PGA), a rare variant of granuloma annulare, is characterized by transepidermal elimination of altered collagen that clinically manifests an umbilicated papule with a central crust. It can be confused with papulonecrotic tuberculid (PNT) because of their similar appearance. Unlike PGA, PNT is usually related to tuberculosis infection with a typical histologic finding of wedgeshaped dermal necrosis. Here, we report the first Korean case of PGA mimicking PNT both clinically and histologically. A 43-year-old Korean woman presented with erythematous papules localized on the extensor surface of her limbs for one year. Some of these papules had a central umbilication or a crust. Regarding comorbidity, she had latent tuberculosis diagnosed with $QuantiFERON^{(R)}-TB$ Gold test about five months ago. She was on antituberculous medication. Initially, a diagnosis of papulonecrotic tuberculid accompanied by latent tuberculosis was considered. However, despite taking the antituberculous medication for five months, her skin lesions were not improved. Biopsy specimen from her arm lesion showed wedge-shaped area of necrosis in the dermis. Additionally, there were multiple focal mucin depositions and palisading granulomatous inflammation throughout the dermis. A diagnosis of PGA was made and she was treated with topical corticosteroid. After two weeks of applying topical corticosteroid, most of her skin lesions disappeared, leaving some hyperpigmented scars.

• Journal of the korean academy of Pediatric Dentistry
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• v.29 no.4
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• pp.581-585
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• 2002

Focal epithelial hyperplasia(FEH) is Human papilloma virus - induced, localized proliferation of oral squamous epithelium. FEH usually occurs in the childhood, but occasionally affects the young and middle-aged adults. Sites of the greatest involvement include the labial, buccal and lingual mucosa, but lesions of gingiva or tongue have also been reported. This disease is typically characterized by multiple soft, non-tender flattened papules and plaques. Occasional lesions show a slight papillary surface change. Individual lesions are small, discrete and well demarcated. The histopathologic hallmark of FEH is acanthosis of the oral epithelium. Cells demonstrating viral cytopathic changes including koilocytes or mitosoid cells may be present. The 5-year-old female of this case visited Department of Pediatric Dentistry, College of Dentistry, Yonsei University with a chief complaint of exophytic lesions on gingiva. Sessile papillary papules were detected by clinical examination on buccal gingiva at the maxillary left and right second deciduous molars. The patient did not complain of pain by palpation. An excisional biopsy was carried out for a histological examination and acanthosis was observed. The lesions were diagnosed as FEH. FEH would regress spontaneously after several months or years. Conservative excision may be performed for diagnostic or esthetic purpose. The risk of recurrence after this therapy is minimal, and there is no malignant transformation.

• CELLMED
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• v.3 no.4
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• pp.30.1-30.3
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• 2013

Eruptive xanthomas that are characterized by yellowish red papules results from hyperlipidemia, particularly hypertriglyceridemia. The hyperlipidemia responsible for this disorder can be caused by a primary genetic defect, a secondary disorder, or both. Some medications such as estrogen or retinoid treatments may cause eruptive xantomas by increasing serum lipids. We present a case eruptive xantomas triggered by hawthorn vinegar.