• Animal Bioscience
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• v.34 no.4
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• pp.701-713
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• 2021

Objective: The present work was undertaken to evaluate the effects of storage time, choline chloride, and high concentrations of Cu and Zn on the kinetic behavior of vitamin degradation during storage in two vitamin premixes and four vitamin-trace mineral (VTM) premixes. Methods: Two vitamin premixes (with or without 160,000 mg/kg of choline) were stored at 25℃ and 60% humidity. Besides, four VTM premixes were used to evaluate the effects of choline (0 vs 40,000 mg/kg) and trace minerals (low CuSO4+ZnO vs high CuSO4+ZnO) on vitamin stability in VTM premixes stored in room, and the VTM premixes were stored in room temperature at 22℃. Subsamples from each vitamin and VTM premix were collected at 0, 1, 2, 3, 6, and 12 months. The retention of vitamin A (VA), vitamin D3 (VD3), vitamin E (VE), vitamin K3 (VK3), vitamin B1 (VB1), vitamin B2 (VB2), vitamin B3 (VB3), vitamin B5 (VB5), and vitamin B6 (VB6) in vitamin premixes and VTM premixes during storage was determined. The stability of vitamins in vitamin premixes and VTM premixes was determined and reported as the residual vitamin activity (% of initial) at each sampling point. Results: The effect of choline on VK3 retention was significant in vitamin premixes (p<0.05). The negative effect of storage time was significant for the retentions of VD3, VK3, VB1, VB2, VB5, and VB6 in vitamin premix (p<0.05). For VTM premixes, negative effect of storage time was significant (p<0.05) for the losses of vitamin in VTM premixes. Choline and high concentrations of Cu and Zn significantly increased VA, VK3, VB1, and VB2 loss during storage (p<0.05). The supplementation of high concentrations of Cu and Zn significantly decreased the concentrations of VD3 and VB6 (p<0.05) in VTM premixes at extended storage time. Conclusion: The maximum vitamin stability was detected in vitamin and VTM premixes containing no choline or excess Cu and Zn. The results indicated that extended storage time increased degradation of vitamin in vitamin or VTM premixes. These results may provide useful information for vitamin and VTM premixes to improve the knowledge of vitamin in terms of its stability.

• Parasites, Hosts and Diseases
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• v.54 no.1
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• pp.31-38
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• 2016

Specific gene expressions of host cells by spontaneous STAT6 phosphorylation are major strategy for the survival of intracellular Toxoplasma gondii against parasiticidal events through STAT1 phosphorylation by infection provoked $IFN-{\gamma}$. We determined the effects of small molecules of tyrosine kinase inhibitors (TKIs) on the growth of T. gondii and on the relationship with STAT1 and STAT6 phosphorylation in ARPE-19 cells. We counted the number of T. gondii RH tachyzoites per parasitophorous vacuolar membrane (PVM) after treatment with TKIs at 12-hr intervals for 72 hr. The change of STAT6 phosphorylation was assessed via western blot and immunofluorescence assay. Among the tested TKIs, Afatinib (pan ErbB/EGFR inhibitor, $5{\mu}M$) inhibited 98.0% of the growth of T. gondii, which was comparable to pyrimethamine ($5{\mu}M$) at 96.9% and followed by Erlotinib (ErbB1/EGFR inhibitor, $20{\mu}M$) at 33.8% and Sunitinib (PDGFR or c-Kit inhibitor, $10{\mu}M$) at 21.3%. In the early stage of the infection (2, 4, and 8 hr after T. gondii challenge), Afatinib inhibited the phosphorylation of STAT6 in western blot and immunofluorescence assay. Both JAK1 and JAK3, the upper hierarchical kinases of cytokine signaling, were strongly phosphorylated at 2 hr and then disappeared entirely after 4 hr. Some TKIs, especially the EGFR inhibitors, might play an important role in the inhibition of intracellular replication of T. gondii through the inhibition of the direct phosphorylation of STAT6 by T. gondii.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.31B no.11
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• pp.116-123
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• 1994

A novel opto-digital pattern recognition method which has shift, rotation, and scale invariant properties is proposed for recognizing two dimensional images having straight lines. The algorithm is composed of three stages. In the first stage the line features of the image are extracted. The second stage imposes the shift, rotation, and scale invariant properties on the extracted features through normalizing procedure. The required normalizing equations are analytically explained. In the last stage, the artificial feedforward neural network is trained with the extracted features. In order to evaluated the proposed algorithm, nine different edge enhnaced binary images composed of straight lines are tested. Thus the proposed algorithm can recognize the patterns event though they are shifted, rotated, and scaled.

• BMB Reports
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• v.39 no.2
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• pp.145-149
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• 2006

To analyze the effect of Maltol on the apoptosis of Human Neuroblastoma Cells (SH-SY5Y) treated by free radical which was generated from Hydrogen Peroxide ($H_2O_2$), flow cytometry analysis on Phosphatidylserine (PS) inverting percentage was applied to determine the apoptosis. MTT (3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl-tetrazolium bromide) assay was employed to analyze the cell viability. DNA electrophoresis was used to detect DNA fragmentation. Moreover intracellular calcium of concentration ($[Ca^{2+}]_i$) was measured by fluorescence emission. Flow cytometry analysis on the function of mitochondria and Western blto analysis of NF-${\kappa}B$. The results showed that the pretreatment with maltol for 2 hours could prevent the $H_2O_2$-induced apoptosis. Maltol could reduce the inverting percentage of PS, DNA fragmentation and $[Ca^{2+}]_i$, and enhance the cellular function of mitochondria. NF-${\kappa}B$ activated by $H_2O_2$ is reduced. The experiments suggest that maltol could effectively inhibit the apoptosis induced by $H_2O_2$. As a novel anti-oxidant, maltol is a new promising drug in protecting the neurological cells from the damage by free radical.

• The KIPS Transactions:PartB
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• v.8B no.5
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• pp.515-522
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• 2001

Feature-based similarity retrieval become an important research issue in image database systems. The features of image data are useful to discrimination of images. In this paper, we propose the highspeed k-Nearest Neighbor search algorithm based on Self-Organizing Maps. Self-Organizing Map(SOM) provides a mapping from high dimensional feature vectors onto a two-dimensional space. A topological feature map preserves the mutual relations (similarity) in feature spaces of input data, and clusters mutually similar feature vectors in a neighboring nodes. Each node of the topological feature map holds a node vector and similar images that is closest to each node vector. We implemented about k-NN search for similar image classification as to (1) access to topological feature map, and (2) apply to pruning strategy of high speed search. We experiment on the performance of our algorithm using color feature vectors extracted from images. Promising results have been obtained in experiments.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.37 no.11
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• pp.43-49
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• 2000

In this paper, we have modeled and fabricated $1{\times}5$ equal power splitter for 1.55${\mu}m$ wavelength using finite-difference beam propagation method and $Ag^+-Na^+$ ion-exchanged method in BK7 glass, respectively. The power splitting ratio could be controlled by changing the center waveguide gap and the inner Y-branch angle. As a result, the power splitting ratio shows 0.46dB when the waveguide width, the inner Y-branch angle and the center waveguide gap are 4.5${\mu}m$, 0.3 degree and 575${\mu}m$, respectively.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.6 s.324
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• pp.33-39
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• 2004

Design of efficient Medium Access Control (MAC) protocols with both high throughput performances is a major focus in distributed contention based MAC protocol research. In this paper, we propose an efficient contention based MAC protocol for wireless Local Area Networks, namely, the Developed Collision Resolution (DCR) algorithm. This algorithm is developed based on the following innovative ideas: to speed up the collision resolution, we actively redistribute the backoff timers for all active nodes; to reduce the average number of idle slots, we use smaller contention window sizes for nodes with successful packet transmissions and reduce the backoff timers exponentially fast when a fixed number of consecutive idle slots are detected. We show that the proposed DCR algorithm provides high throughput performance and low latency in wireless LANs.

• Journal of Gastric Cancer
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• v.20 no.1
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• pp.81-94
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• 2020

Purpose: Duodenal stump leakage (DSL) is a potentially fatal complication that can occur after gastrectomy, but its underlying risk factors are unclear. This study aimed to investigate the risk factors and management of DSL after laparoscopic radical gastrectomy for gastric cancer (GC). Materials and Methods: Relevant data were collected from several prospective databases to retrospectively analyze the data of GC patients who underwent Billroth II (B-II) or Rouxen-Y (R-Y) reconstruction after laparoscopic gastrectomy from 2 institutions (Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, and HwaMei Hospital, University of Chinese Academy of Sciences). The DSL risk factors were analyzed using univariate and multivariate analysis regression. Results: A total of 810 patients were eligible for our analysis (426 with R-Y, 384 with B-II with Braun). Eleven patients had DSL (1.36%). Body mass index (BMI), elevated preoperative C-reactive protein (CRP) level, and unreinforced duodenal stump were the independent risk factors for DSL. DSL was diagnosed in 2-12 days, with a median of 8 days. Seven patients received conservative treatment, 3 patients received puncture treatment, and only 1 patient required reoperation. All patients recovered successfully after treatment. Conclusions: The risk factors of DSL were BMI ≥24 kg/㎡, elevated preoperative CRP level, and unreinforced duodenal stump. Nonsurgical treatments for DSL are preferred.

• Korean Journal of Computational Design and Engineering
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• v.19 no.4
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• pp.356-367
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• 2014

A robotic sapatial augmented reality (RSAR) system, which combines robotic components with projector-based AR technique, is unique in its ability to expand the user interaction area by dynamically changing the position and orientation of a projector-camera unit (PCU). For a moving PCU mounted on a conventional robotic device, we can compute its extrinsic parameters using a robot kinematics method assuming a link and joint geometry is available. In a RSAR system based on user-created robot (UCR), however, it is difficult to calibrate or measure the geometric configuration, which limits to apply a conventional kinematics method. In this paper, we propose a data-driven kinematics control method for a UCR-based RSAR system. The proposed method utilized a pre-sampled data set of camera calibration acquired at sufficient instances of kinematics configurations in fixed joint domains. Then, the sampled set is compactly represented as a set of B-spline surfaces. The proposed method have merits in two folds. First, it does not require any kinematics model such as a link length or joint orientation. Secondly, the computation is simple since it just evaluates a several polynomials rather than relying on Jacobian computation. We describe the proposed method and demonstrates the results for an experimental RSAR system with a PCU on a simple pan-tilt arm.

• Korean Journal of Agricultural and Forest Meteorology
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• v.10 no.4
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• pp.141-148
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• 2008

This study was conducted to investigate the photosynthetic responses of four Oak species (Quercus mongolica, Q. serrata, Q. acutissima and Q. variabilis) by shading treatment. We investigated light response curve, photosynthesis (A)-intercellular $CO_2$ concentration (Ci) curve, leaf growth and chlorophyll content at the level of 35, 55 and 75% shading treatments and under the full sunlight. In our results, Q. variabilis and Q. acutissima showed increased leaf growth, chlorophyll content and net apparent quantum yield but reduced chlorophyll a/b and carboxylation efficiency under the low light intensity. Therefore, light absorption and light utilization efficiency were improved under the low light intensity. Q. mongolica showed the similar responses that Q. variabilis and Q. acutissima showed, but net apparent quantum yield was reduced. The effects of shading treatment on Q. serrata were lower than those of other three species.