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An integrated CAD system for blanking or piercing of irregular-shaped sheet metal products (불규칙형상의 박판제품에 관한 블랭킹 및 피어싱용 통합적 CAD시스템)

  • Choi, Jae-Chan;Kim, Byung-Min;Kim, Chul;Yoon, J.H.
    • Journal of the Korean Society for Precision Engineering
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    • v.15 no.2
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    • pp.124-133
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    • 1998
  • This paper describes a research work of developing a computer-aided design of blanking and piercing for irregular-shaped sheet metal products. An approach to the development of compact and practical CAB system is based on the knowledge-based rules. Knowledge for the CAD system is formulated from plasticity theories, experimental results and the empirical knowledge of field experts. The system has been written in AutoLISP on the AutoCAD with a personal computer. Based on knowledge-based rules, the system, STRT-DES, is designed by considering several factors, such as complexities of blank geometry and punch profile, availability of press equipment and standard parts, utilization ratio which minimizes the scrap in a single or a pairwise operation, bridge width, grain orientation and design requirements which maximize the strength of the part when subsequent bending is involved. This system checks a forming feasibility with both internal and external features, a dimension of blanked hole, and a corner and a fillet radius for irregualrly shaped sheet metal products. Therefore this system can carry out a die design for each process which is obtained from results of an automated blank layout drawing with a best utilization ratio for irregular shape of product that was successful in production feasibility check module and those of an automated strip layout drawing and generate part drawings and the assembly drawing of die set in graphic forms.

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Predictive Value of the Platelet-To-Lymphocyte Ratio in Diagnosis of Prostate Cancer

  • Yuksel, Ozgur Haki;Urkmez, Ahmet;Akan, Serkan;Yldirim, Caglar;Verit, Ayhan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.15
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    • pp.6407-6412
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    • 2015
  • Purpose: To predict prostatic carcinoma using a logistic regression model on prebiopsy peripheral blood samples. Materials and Methods: Data of a total of 873 patients who consulted Urology Outpatient Clinics of Fatih Sultan Mehmet Training and Research Hospital between February 2008 and April 2014 scheduled for prostate biopsy were screened retrospectively. PSA levels, prostate volumes, prebiopsy whole blood cell counts, neutrophil and platelet counts, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), biopsy results and Gleason scores in patients who had established diagnosis of prostate cancer (PCa) were evaluated. Results: This study was performed on a total of 873 cases, with an age range 48-76 years, divided into three groups as for biopsy results. with diagnoses of benign prostatic hyperplasia (BPH) (n=304, 34.8 %), PCa (n=265, 30.4 %) and histological prostatitis (n=304; 34.8 %). Intra- and intergroup comparative evaluations were performed. White blood cell and neutrophil counts in the histological prostatitis group were significantly higher than those of the BPH and PCa groups (p=0.001; p=0.004; p<0.01). A statistically significant intergroup difference was found for PLR (p=0.041; p<0.05) but not lymphocyte count (p>0.05). According to pairwise comparisons, PLR were significantly higher in the PCa group relative to BPH group (p=0.018, p<0.05, respectively). Though not statistically significant, higher PLR in cases with PCa in comparison with the prostatitis group was remarkable (p=0.067, and p>0.05, respectively). Conclusions: Meta-analyses showed that in patients with PSA levels over 4 ng/ml, positive predictive value of PSA is only 25 percent. Therefore, novel markers which can both detect clinically significant prostate cancer, and also prevent unnecessary biopsies are needed. Relevant to this issue in addition to PSA density, velocity, and PCA3, various markers have been analyzed. In the present study, PLR were found to be the additional predictor of prostatic carcinoma.

Application of Analytic Hierarchy Process for Relative Importance Determination of Internet of Things Standardization (사물인터넷 표준화의 상대적 중요도 결정을 위한 계층분석방법 응용)

  • Woo, Hoon-Shik
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.39 no.1
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    • pp.47-55
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    • 2016
  • As one of recent issues in the information and communication industry, internet of things has attracted attention to provide intelligent infrastructure services which connect and share data and information between real and virtual world. According to the development of these internet of things technologies, types of machines, telecommunication devices, and terminals are increasing tremendously. In this situation, connectivity and interoperability between internet of things components are important issues to build a hyper connected society. To visualize this society, it is important to set up and develop information and communication technology (ICT) standards among stakeholders. However, under limited budget and human resources, it is essential to rank standardization work items for setting standards with respect to efficiency. The purpose of this study is to provide a method for setting standardization strategies within group decision making. As a multi-criteria group decision making tool, analytic hierarchy process (AHP) is adopted and applied to determine the priorities of setting work items. The proposed method first defines decision making problem with objective, criteria, and alternatives which produces a hierarchy consisting of upper and lower criteria. Then, pairwise comparisons of academy and public sector experts are performed with respect to their relative meaning and importance. Individual surveys of expert groups are collected and summarized to determine relative criteria importance measures. Furthermore, to deliver reliable importance criteria measures, differences between academy and public sector expert groups are compared and tested using Mann-Whitney non-parametric test. The results are illustrated for useful guidelines to practical group decision making in standardization strategy establishments.

Development and validation of SSR markers in Eleutherococcus senticosus

  • Lee, Kyung Jun;An, Yong-Jin;Ham, Jin-Kwan;Ma, Kyung-Ho;Lee, Jung-Ro;Cho, Yang-Hee;Lee, Gi-An
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.84-84
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    • 2017
  • Eleutherococcus senticosus (Siberian ginseng) is an important medicinal tree found in Russian taiga, and northern regions of Korea, Japan, and China. In this study, we analyzed the genome-wide distribution of microsatellites in E. senticosus using developed SSR markers. A total of 711 clones from an SSR-enriched genomic DNA library were sequenced, of which 47 clones (6.6%) were redundant. Of the 664 independent clones, only 12 polymorphic SSR markers were obtained, which also revealed successful amplicons in E. senticosus accessions. Using the developed SSR markers, we estimated genetic diversity and population structure among 131 E. senticosus accessions in Korea and China. The number of alleles ranged from 2 to 11, with an average of 7.4 alleles. The mean values of observed heterozygosity ($H_O$) and expected heterozygosity ($H_E$) were 0.59 and 0.56, respectively. The average polymorphism information content (PIC) was 0.51 in all 131 E. senticosus accessions. E. senticosus accessions in Korea and China showed a close genetic similarity. Significantly low pairwise genetic divergence was observed between the two regions, suggesting a relatively narrow level of genetic basis among E. senticosus accessions. Our results not only provide molecular tools for genetic studies in E. senticosus but are also helpful for conservation and E. senticosus breeding programs.

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Study on the development of Quantitative assessment indicator of safety culture for the construction site (건설현장 안전문화의 정량적 평가지표 개발에 관한 연구)

  • Jun, Heakyung;Kwon, Changhee
    • Journal of the Society of Disaster Information
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    • v.12 no.4
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    • pp.403-411
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    • 2016
  • The objectives of this study is to develop evaluation indicators for the quantitative evaluation of construction safety culture level in order to prevent accidents by evaluating the level of safety culture and each safety culture elements of the construction site and to present the areas that should be focused on improvements. In this study, it was presented assessment indicators of the construction safety culture by analyzing previous studies for safety culture, by categorizing items as an important element of safety culture hierarchically and by reflecting the opinion of the construction site professional personnels using AHP analysis methodology. The assessment indicators of the construction safety culture were structured the details of the leadership, systems, and personal characteristics and derived weighted value by the pairwise comparison to quantify the detail assessment indicators in order to assess the construction safety culture level. This study presents a safety culture assessment indicators for the construction site to suggest directions for improving the construction site safety culture and prevent the accidents of the construction site by derived via a safety culture assessment of construction site.

The Analysis of Priorities of Roads Investment Using Analytic Hierarchy Process (AHP를 이용한 도로사업의 우선순위 분석)

  • 정병두
    • Journal of Korean Society of Transportation
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    • v.20 no.5
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    • pp.45-54
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    • 2002
  • The Analytic Hierarchy Process (AHP) has been widely used as a comprehensive evaluation method since it can include various evaluation standards of both the public and private sectors. It also provides the objective mathematics to process subjective and Personal preferences of an individual or a group in making a decision. This study tried to use AHP to determine the priority of roads investment, considering various effects in a hierarchy such as environmental effects, residential life, and regional development which has not been treated explicitly. As a case study, roads in Gyeongsangbukdo province have been chosen for the evaluation in this research. For the application, it used relative measurements to estimate the weight of upper level structure, and absolute measurement for low level structure instead of pairwise comparisons.

Molecular Cloning of Cytochrome P450 Family Gene Fragment from Midgut of the Beet Armyworm, Spodoptera exigua

  • Moon, Jae-Yu;Lee, Pyeongjae;Cho, Il-Je;Kim, Iksoo;Lee, Heui-Sam
    • International Journal of Industrial Entomology and Biomaterials
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    • v.4 no.2
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    • pp.155-162
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    • 2002
  • Cytochrome P45O (CYP) gene has been known to play one of the most important roles in metabolizing the exogenous materials. In insect, CYP is particularly known to detoxify toxic materials by adding oxygen molecule to the hydrophobic region of the materials. Thus, CYP-dependent metabolism is associated with the adaptation of insect to host plant chemicals. This in turn is known to be one of the driving forces for CYP diversification. In the present study, we cloned seven gene fragments of CYP 4 (CYP4) family from the midgut of the beet armyworm, Spodoptera exigua, through RT.PCT, Sequence analysis of the product showed the gene fragment to contain an open reading frame of ~150 amino acids, consisted of ~450 bp. The cloned gene fragments contained typical, conserved regions found in CYP4 family. Pairwise comparison of the deduced amino acid sequences among seven clones ranged in divergence from 0% to 52.86% and resulted in five distinct clones. The other two clones were identical or differ by one amino acid respectively to the corresponding clone, although each differed by ten nucleotides. Analysis of correlation between GenBank-registered, full length CYP4 and the cloned fragments resulted in statistically significant relationship ($r^{2}$ = 0.96085; p < 0.001), suggesting utility of the partial sequences as such full-length sequences. Phylogenetic analysis of the clones with GenBank-registered insect and mammal CYP4 family sequences by parsimony and several distance methods subdivided the clones into two groups: tones belonging to CYP4S and the others to CYP4M families.

Establishment of a Fuzzy Multi-criteria Decision Making Method Framework for Selecting R&D Programs of Energy Technologies (에너지기술 R&D 프로그램 선정을 위한 퍼지 다기준의사결정 프레임워크 수립)

  • Lee, Seong-Kon;Mogi, Gento;Kim, Jong-Wook
    • Journal of Hydrogen and New Energy
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    • v.20 no.1
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    • pp.22-30
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    • 2009
  • Energy environment has been changing rapidly such as the fluctuation of oil prices and the effect on UNFCCC. Oil price change affects Korea's economy heavily due to her poor natural resources and large dependence of consumed energy resources. Korea takes the 4th place of importing the crude oil and 9th place in $CO_2$ emissions with the 1st place of $CO_2$ emissions increasing rate. Considering the current statue of Korea including oil price change and UNFCCC, Korea will be expected to be the Annex I nation due to Korean energy environments and the quantity of $CO_2$ emission. Energy technology development is a crucial key to cope with Korea's national energy security and environments. In this study, we establish the framework, which allocates the relative weights of assessment criteria and sub-criteria, for assessing and selecting R&D programs of energy technologies strategically. We integrated fuzzy theory and analytic hierarchy process (AHP) approach since the fuzzy AHP approach reflects the vagueness of human thoughts and perception effectively as making pairwise comparisons of criteria and alternatives. The fundamental data of this research results will support R&D planning phase for policy-makers and the production of well focused R&D outcomes.

Comparison of changes in retentive force of three stud attachments for implant overdentures

  • Kim, Su-Min;Choi, Jae-Won;Jeon, Young-Chan;Jeong, Chang-Mo;Yun, Mi-Jung;Lee, So-Hyoun;Huh, Jung-Bo
    • The Journal of Advanced Prosthodontics
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    • v.7 no.4
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    • pp.303-311
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    • 2015
  • PURPOSE. The aim of this study was to compare the changes in retentive force of stud attachments for implant overdentures by in vitro 2-year-wear simulation. MATERIALS AND METHODS. Three commercially available attachment systems were investigated: Kerator blue, O-ring red, and EZ lock. Two implant fixtures were embedded in parallel in each custom base mounting. Five pairs of each attachment system were tested. A universal testing machine was used to measure the retentive force during 2500 insertion and removal cycles. Surface changes on the components were evaluated by scanning electron microscopy (SEM). A Kruskal-Wallis test, followed by Pairwise comparison, was used to compare the retentive force between the groups, and to determine groups that were significantly different (${\alpha}$<.05). RESULTS. A comparison of the initial retentive force revealed the highest value for Kerator, followed by the O-ring and EZ lock attachments. However, no significant difference was detected between Kerator and O-ring (P>.05). After 2500 insertion and removal cycles, the highest retention loss was recorded for O-ring, and no significant difference between Kerator and EZ lock (P>.05). Also, Kerator showed the highest retentive force, followed by EZ lock and O-ring, after 2500 cycles (P<.05). Based on SEM analysis, the polymeric components in O-ring and Kerator were observed to exhibit surface wear and deformation. CONCLUSION. After 2500 insertion and removal cycles, all attachments exhibited significant loss in retention. Mechanism of retention loss can only be partially explained by surface changes.

Shear bond strength of luting cements to fixed superstructure metal surfaces under various seating forces

  • Ozer, Fusun;Pak-Tunc, Elif;Dagli, Nesrin Esen;Ramachandran, Deepika;Sen, Deniz;Blatz, Markus Bernhard
    • The Journal of Advanced Prosthodontics
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    • v.10 no.5
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    • pp.340-346
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    • 2018
  • PURPOSE. In this study, the shear bond strengths (SBS) of luting cements to fixed superstructure metal surfaces under various seating forces were investigated. MATERIALS AND METHODS. Seven different cements [Polycarboxylate (PCC), Glass-Ionomer (GIC), Zinc phospahate (ZPC), Self-adhesive resin (RXU), Resin (C&B), and Temporary cements ((RXT) and (TCS))] were bonded to a total number of 224 square blocks ($5{\times}5{\times}3mm$) made of one pure metal [Titanium (CP Ti) and two metal alloys [Gold-Platinum (Au-Pt) and Cobalt-Chrome (Co-Cr)] under 10 N and 50 N seating forces. SBS values were determined and data were analyzed with 3-way ANOVA. Pairwise comparisons and interactions among groups were analyzed with Tukey's simultaneous confidence intervals. RESULTS. Overall mean scores indicated that Co-Cr showed the highest SBS values ($1.96{\pm}0.4$) (P<.00), while Au-Pt showed the lowest among all metals tested ($1.57{\pm}0.4$) (P<.00). Except for PCC/CP Ti, RXU/CP Ti, and GIC/Au-Pt factor level combinations (P<.00), the cements tested under 10 N seating force showed no significantly higher SBS values when compared to the values of those tested under 50 N seating force (P>.05). The PCC cement showed the highest mean SBS score ($3.59{\pm}0.07$) among all cements tested (P<.00), while the resin-based temporary luting cement RXT showed the lowest ($0.39{\pm}0.07$) (P<.00). CONCLUSION. Polycarboxylate cement provides reliable bonding performance to metal surfaces. Resin-based temporary luting cements can be used when retrievability is needed. GIC is not suitable for permanent cementation of fixed dental prostheses consisting of CP Ti or Au-Pt substructures.