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Plasma Cholesterol-Lowering Effects of Cinnamomi cortex Extract as an Inhibitor of Pancreatic Cholesterol Esterase (췌장 콜레스테롤 에스터레이즈 저해제로서의 계피 추출물레 혈중 콜레스테롤 농도에 미치는 영향)

  • 김희숙;최종원;허영미;류성호;서판길
    • Journal of Life Science
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    • v.12 no.1
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    • pp.106-112
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    • 2002
  • Ethanol extract of Cinnamomi cortex inhibited potently cholesterol esterase activity in vitro. Chloroform fraction of ethanol extract showed the stronger inhibitory effect than other solvent fractions - ethylacetate fraction, butanol fraction, and aqueous fraction. The chloroform fraction of Cinnamomi cortex was studied as a candidator of plasma cholesterol-lowering material using high cholesterol-fed rats. In high cholesterol-fed rats, the diet with chloroform fraction of 150 mg/kg lowered not only plasma neutral lipids contents 25.1% but also plasma total cholesterol level 49.6% than only high cholesterol diet. Plasma HDL-cholesterol level in Cinnamomi cortex chloroform fraction-fed rats was recovered as those level of normal rats. LD$_{50}$ of Cinnamomi chloroform extract was calculated as 1,300 mg/kg.

Effect of Extreme Light Regime on Production and Characteristics of Egg in Laying Geese

  • Wang, S.D.;Wang, C.M.;Fan, Y.K.;Jan, D.F.;Chen, L.R.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.8
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    • pp.1182-1185
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    • 2002
  • The objective of this study was to investigate the effect of long light regime (20 h light and 4 h dark, 20L:4D) and short light regime (4 h light and 20 h dark, 4L:20D) on egg production and egg characteristics of laying geese. Thirty-six laying birds, 4 replicates of 3 birds per treatment were allotted to three light regimes, i.e., 20L:4D, 4L:20D, and natural light (NAT) from March 7 to June 20. Results showed that the geese in 20L:4D consumed 54 g less feed per goose daily and laid 17.5 less eggs per goose (p<0.05) comparing to those in 4L:20D. The number of days from initiation of light treatment till cease of laying was 22 days shorter (p<0.05) in 20L:4D comparing to that in NAT. Five geese (41.7%) in 4L:20D kept laying by the end of applying light regime. Weight and surface area of the eggs in 4L:20D were greater (p<0.05) comparing to those in the other two light regimes. It is concluded that the period of egg production in goose could be manipulated by light regime in the ways such as using short light regime of 4 h light daily to prolong egg production through summer and using long light regime of 20 h light daily to induce cease of egg production.

Analysis of Factors Affecting the Smoking Rates Gap between Regions and Evaluation of Relative Efficiency of Smoking Cessation Projects (지역 간 흡연율 격차 영향요인 분석 및 금연사업 상대적 효율성 평가: Clustering Analysis와 Data Envelopment Analysis를 활용하여)

  • Kim, Heenyun;Lee, Da Ho;Jeong, Ji Yun;Gu, Yeo Jeong;Jeong, Hyoung Sun
    • Health Policy and Management
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    • v.30 no.2
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    • pp.199-210
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    • 2020
  • Background: Based on the importance of ceasing smoking programs to control the regional disparity of smoking behavior in Korea, this study aims to reveal the variation of smoke rate and determinants of it for 229 provinces. An evaluation of the relative efficiency of the cease smoking program under the consideration of regional characteristics was followed. Methods: The main sources of data are the Korean Statistical Information Service and a national survey on the expenditure of public health centers. Multivariate regression is performed to figure the determinants of regional variation of smoking rate. Based on the result of the regression model, clustering analysis was conducted to group 229 regions by their characteristics. Three clusters were generated. Using data envelopment analysis (DEA), relative efficiency scores are calculated. Results from the pooled model which put 229 provinces in one model to score relative efficiency were compared with the cluster-separated model of each cluster. Results: First, the maximum variation of the smoking rate was 16.9%p. Second, sex ration, the proportion of the elder, and high risk drinking alcohol behavior have a significant role in the regional variation of smoking. Third, the population and proportion of the elder are the main variables for clustering. Fourth, dissimilarity on the results of relative efficiency was found between the pooled model and cluster-separated model, especially for cluster 2. Conclusion: This study figured regional variation of smoking rate and its determinants on the regional level. Unconformity of the DEA results between different models implies the issues on regional features when the regional evaluation performed especially on the programs of public health centers.

A Study on Female Sexual Dysfunction, Sexual Distress, Sexual Attitude and Knowledge in Korean Women (여성의 성기능 장애와 성 스트레스, 성태도 및 성지식과의 관계 연구)

  • Bae, Jeong-Yee
    • Women's Health Nursing
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    • v.10 no.4
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    • pp.342-350
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    • 2004
  • Purpose: It has been suggested that approximately 40% of women between 40 and 64 years of age cease their sexual activity. The aim of this study was to establish the basic data for FSD(female sexual dysfunction) and FSD-related factors in regional urban and rural areas of Korea. Method: Three hundred twenty five women over 20 years of age and resident in regional urban and rural areas were analyzed by a visit survey with an organized questionnaire. The female sexual function index(FSFI) for measurement of sexual dysfunction was used. The significance between the degree of sexual dysfunction and characteristics of the participants was analyzed by a t-test and ANOVA test. The relationship between the degree of sexual dysfunction and related factors was analyzed by Pearson's correlation coefficient. Results: All analyzing tools including the FSFI had a high validity for measuring. The FSFI in Korean women was $19.97{\pm}4.87$ and ranged from 2 to 29. Old age, menopause, medication, no contraception usage and longer marital duration were significantly related with a lower FSFI score. Pearson's correlation coefficient revealed the significance in degrees of sexual distress (r=-.469, p=.000), sexual attitude(r=.305, p=.000) and a stressful life event(r= -.141, p=.038) with the sexual function index score. Conclusion: Women with sexual dysfunction should be evaluated for these sexual function-related factors in the history taking, and this data can be a basis for study for sexual dysfunction.

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A Comparative Study of Antegrade Cardioplegia Versus Retrograde Cardioplegia for Myocardial Protection during the Open Heart Surgery (순행성 관관류법과 역행성 관관류법의 임상적 비교연구)

  • 조완재
    • Journal of Chest Surgery
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    • v.22 no.4
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    • pp.609-619
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    • 1989
  • During aortic valve surgery, cardioplegic solution is delivered through direct cannulation of both coronary ostia. Since this approach may cause an intimal injury leading to acute dissection or late ostial stenosis, this study was undertaken to evaluate myocardial protective effect of retrograde perfusion of cardioplegia [RCSP <% RRAP] in 18 clinical cases, which were compared with antegrade perfusion of cardioplegia in 27 clinical cases. This study were investigated 1] cease and return of electromechanical activity after cardioplegia infusion 2] the myocardial temperature during operation 3] the aortic cross clamping time and total bypass time 4] frequency of DC shock for defibrillation 5] need for inotropic drugs after operation 6] electrocardiographic evidence of myocardial infarction or ventricular arrhythmia after operation 7] the enzymes activity during preoperative and postoperative period as an evaluation of myocardial ischemic injury and 8] operative mortality rate The combination of retrograde cardioplegia and topical cooling with ice slush yielded promptly hypothermia of myocardium and shorter aortic cross-clamping time compared with antegrade cardioplegia [P < 0.05]. The temperature of the interventricular septum was maintained below 20oC by continuous perfusion or intermittent perfusion of cold blood cardioplegia and other results were no statistically significant difference between the two methods [P >0.05]. This technique provides clear operative field and avoids some serious complications which are caused by coronary ostial cannulation. These results suggested that the retrograde perfusion of cardioplegia is a simple, safe, and effective means of myocardial protection during open heart surgery.

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In Vitro Culture of Nontransformed Cell Lines Derived from Rat Endometrial Epithelium and Stroma (흰쥐 자궁 상피와 내막에서 기원한 세포주의 체외배양)

  • Kang, Byung-Moon;Lee, Suk-Won;Chae, Hee-Dong;Kang, Eun-Hee;Chu, Hyung-Sik;Kim, Chung-Hoon;Chang, Yoon-Seok;Nam, Joo-Hyun
    • Clinical and Experimental Reproductive Medicine
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    • v.26 no.1
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    • pp.83-87
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    • 1999
  • Since the blastocyst is broken and spreads out on a flat plastic culture dish (two dimensional culture) during in vitro development, it has been difficult to study the implantation process. It also has been difficult to analyse the interactions between endometrial epithelial and stromal cells because of the lack of a long-term in vitro model which can stimulate in vivo characteristics, as these cells eventually fail to proliferate or cease to express differentiated functions. Recently nontransformed cell lines, CUE-P and CUS-V2, derived from rat endometrial epithelium and stroma were reported. In this study, morphology of CUE-P and CUS-V2 was examined and oxytocin gene expression by CUE-P cells was demonstrated by RT-PCR. The CUE-P cells have a cuboidal morphology and CUS-V2 cells resemble fibroblast and exhibit a spindle-like morphology. In RT-PCR, same size of PCR products of oxytocin gene at hypothalamus, uterus and CUE-P cells were demonstrated. These results showed three dimensional culture system could be made by using the new cell lines.

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A Grounded Theory Approach to the Process of Conflict between Early Childhood Teacher and Parent on the Perspectives of Teachers (유아교사의 관점에서 본 교사와 학부모의 갈등과정 : 근거이론적 접근)

  • Kim, Young Ju;Lee, Kyeong Hwa
    • Korean Journal of Childcare and Education
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    • v.11 no.5
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    • pp.237-260
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    • 2015
  • This study sought to explain the process of conflict between early childhood teacher and parent (T-P conflict) and was guided by the following three questions: (a) how does a T-P conflict begin? (b) how does a T-P conflict develop over time? and (c) how does a T-P conflict end? One hundred cases were provided by private kindergarten teachers with experiences of T-P conflict. A qualitative grounded theory design was used for analysis of the data. Open coding and axial coding resulted in six categories: (a) "causes of conflict" (b) "conditional context of conflict" (c) "state of conflict" (d) "amplification of conflict" (e) "problem solving strategies of conflict", and (f) "cease of conflict". The stage of selective coding drew out three core categories: (a) "prelude with tuneless instruments" (b) "duet for discords and concords, and (c) "splendid finale vs. unplanned intermission". Additionally the study raised the doubts about current early childhood education policies based on neo-liberalism and their impacts on relationships between teachers and parents.

Effect of Cooking on the Food Safety of Cutlet - Changes of Internal Temperature, Color, and Indicator Organisms - (가열 처리에 따른 커틀릿의 식품안전성 확보 조건 - 내부 중심온도, 색도 및 위생지표미생물을 중심으로 -)

  • Kim, Jong-Gyu;Kim, Joong-Soon
    • Journal of Environmental Health Sciences
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    • v.41 no.2
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    • pp.82-89
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    • 2015
  • Objectives: This study was performed to investigate the effect of cooking time on the internal temperature and color of cutlets and the reduction of indicator organisms in cutlets by cooking. Methods: Three kinds of commercially packed frozen cutlets (pork, chicken and fish cutlets), were purchased from local markets. The cutlets were cooked in a frying pan at $180^{\circ}C$ for four minutes. Internal temperature was measured with a food thermometer. Color was measured using a Hunter spectrocolorimeter. Aerobic colony counts, coliforms, and Escherichia coli were determined according to the Food Code of Korea. Results: The internal cooked temperature of every cutlet reached over $74^{\circ}C$, the temperature considered safe, after three minutes, while external temperature reached this level in two minutes (p < 0.001). The instrumental color value as lightness (L) in the cooked cutlets significantly changed (p < 0.001) after one minute. The level of aerobic colony counts of fresh cutlets was under the specification and was reduced to one tenth its level in the cooked cutlets. Coliforms and E. coli were not detected in all samples. The internal temperature of the cutlets was significantly affected by cooking time and weight (p < 0.001). The interaction effect of time and weight was also significant (p < 0.001), and time was the more influential factor. Conclusion: The results of this study indicate that the sampled cutlets should be cooked for a minimum of three minutes or more in order to ensure food safety. The results also indicate that if consumers cease cooking based on external temperature or color, there will be a risk of inadequate cooking.

Hearing Restoration Operation (청력증진술)

  • 소진명;김형곤;전승하
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1979.05a
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    • pp.3.1-3
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    • 1979
  • The aim of ear operation is to cease otorrhea and to restore hearing. The ceasation of otorrhea and the graft of tympanic membrane are reached to successful stage, and yet hearing restoration process still remains further to need a matter of development. Authors carried out 67 cases hearing restoration operation among 154 patients who had been undertaken mastoid-tympanoplasty during period of Feb. 1978 through March 1979. 54 cases have been followed for this study among 67 cases hearing restoration operation. The used material of operation are almostly incus and some cases with TORP. This paper is dealing with its surgical method and postoperative audimetric study.

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Spiral Structure and Mass Inflows in Barred-Spiral Galaxies

  • Kim, Yonghwi;Kim, Woong-Tae
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.2
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    • pp.39.1-39.1
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    • 2013
  • We use high-resolution hydrodynamic simulations to study nonlinear gas responses to imposed non-axisymmetric stellar potentials in barred-spiral galaxies. The gas is assumed to be infinitesimally thin, isothermal, and unmagnetized. We consider various spiral-arm models with differing strength and pattern speed, while fixing the bar parameters. We find that the extent and shapes of spiral shocks as well as the related mass drift depend rather sensitively on the pattern speed. In models where the arm pattern is rotating more slowly than the bar, the gaseous arms extend from the bar ends all the way to the outer boundary, with a pitch angle slightly smaller than that of the stellar counterpart. The arms drive mass inflows at a rate of ${\sim}0.5-2.5M{\odot}/yr$ to the bar region to which the shock dissipation, external torque, and self-gravitational torque contribute about 50%, 40%, and 10%, respectively. About 85% of the inflowing mass is added to bar substructures such as an inner ring, dust lanes, and a nuclear ring. while the remaining 15% encircles the bar region. On the other hand, models where the arms corotate with the bar exhibit mass outflows, rather than inflows, over most of the arm region. In these models, spiral shocks are much more tightly wound than the stellar arms and cease to exist in the region where $M{\bot}/sinp*{\geq}25-40$, where $M{\bot}$ denotes the Mach number of a rotating gas perpendicular to the arms with pitch angle p*. We demonstrate that the distributions of line-of-sight velocities and densities can be a useful diagnostic tool to distinguish if the arms and bar corotate or not.

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