• Applied Biological Chemistry
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• v.39 no.1
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• pp.60-66
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• 1996

To investigate a possible application of three strains of lactic acid bacteria(strain No. 49. No. 61. No. 75) from kimchi in milk fermentation industry, the optimal condition for production of intracellular ${\beta}-galactosidase$ from Lactobacillus(L.) plantarum and its enzymatic properties were examined. The preferable carbon source of the medium for strain No. 49 in production of ${\beta}-galactosidase$ was MRS broth with 1.0% lactose instead of dextrose of pH 65. for strain No. 75 with 1.0% galactose and for strain No. 61 with 3.0% lactose at pH 7.5, respectively. The maximum enzyme production from strain No. 49, No. 75 was observed after 48 hours culture at $30^{\circ}C$ in a medium containing the appropriate carbon source, from strain No. 61 after 48 hours culture at room temperature. The optimum temperature for ${\beta}-galactosidase$ activity from L. plantarum was $60^{\circ}C$ for strain No. 49, $37^{\circ}C$ for strain No. 61 and $50^{\circ}C$ for strain No. 75, respectively. The heat stability of enzyme activities for all three strains remained 90% at $45^{\circ}C$. The optimal pH was pH 6.5 and enzyme activities were most stable at pH for all three bacteria.

• The Korean Journal of Community Living Science
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• v.23 no.4
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• pp.501-508
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• 2012

In order to find the effect of improving hyperlipidemia by Acanthopanax senticosus water extract, a hypercholesterol diet and Acanthopanax senticosus water extract were supplemented to week- old male Spargue Dawley rats for four weeks in different amount. Results showed that serum total cholesterol significantly decreased in the group supplemented with Acanthopanax senticosus water extract by 50mg/kg(ASW-50) and 75mg/kg(ASW-75) compared with the control group.(p<0.05). Serum triglyceride also showed a significant decrease in the group supplemented with 50mg/kg(ASW-50) and 75mg/kg(ASW-75) compared with the control group. Liver total cholesterol showed a significant decrease in the group supplemented with Acanthopanax senticosus water extract by 50mg/kg(ASW-50) and 75mg/kg(ASW-75) compared with the control group(p<0.05), but liver triglyceride did not show a significant decrease in all of the experiment groups. Total cholesterol and triglyceride in feces significantly increased in all of the groups supplemented with Acanthopanax senticosus water extract(p<0.05). Acanthopanax senticosus water extract decreased the level of serum total cholesterol and triglyceride, reduced total cholesterol in the liver, and increased the excretion of total cholesterol and triglyceride in the feces.

• Biotechnology and Bioprocess Engineering:BBE
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• v.2 no.2
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• pp.122-125
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• 1997

The utilization of excess whey is necessary to reduce dairy waste because the large amount of whey disposal in waste streams has caused environmental problems. During whey protein film production as the effective means of utilization of excess whey, we have examined the effects of pH, temperature, and plasticizers for water vapor permeability(WVP), tensile strength(TS), and elongation rate(%E) of the whey protein films. The 10% whey protein films had the highest WVP(28.73g$.$mm/kPa$.$day$.$㎡) and TS(1.85${\pm}$0.11Mpa). But, in this case, an increase of WVP was caused by the thickness of whey protein films. At the concentration of 8% whey protein, appropriate thickness was obtained. Whey protein films prepared at the pH 6.75 and 95$^{\circ}C$ showed lower WVP(28.38g$.$mm/kPa$.$day$.$㎡) and elongation rate(12.9%) and higher TS value(3.769${\pm}$0.407 MPa) than at the pH 6.75 and 75$^{\circ}C$. As the temperature increased, WVP of films decreased slightly and tensile strength increased slightly, while elongation rate decreased significantly. Higher WVP and TS were observed at pH6.75 compared to pH7-9. In contrast, significantly higher elongation was observed at pH 9comapred to pH6.75-8. Among the plasticizer types used, the addition of sorbitol showed the highest TS value(6.244${\pm}$0.297 MPa) at the concentration 0.4g sorbitol and elongation rate(49%) at the concentration of 0.6g sorbitol.

• Physical Therapy Korea
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• v.26 no.4
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• pp.63-69
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• 2019

Background: Both the rapid concentric and eccentric contractions during exercise repeatedly impose excessive stress on muscle tissue. The hamstring muscles are very susceptible to injury due to the tensile stress. Various interventions are currently being undertaken to prevent strain injury before exercise. Stretching is the most common method and is known to have a positive effect on flexibility and muscle performance. However, relatively few studies have investigated the potential negative factors of stretching. Objects: The purpose of this study was to examine changes in pain following the different intensity of the stretching and types of physical stress. Methods: The subjects were divided into three groups based on the intensity of stretching: 100% (S100), 75% (S75), and 50% (S50) of the measured force at the point of discomfort in static stretching and 100% (P100), 75% (P75), and 50% (P50) of the maximum voluntary isometric contraction in Proprioceptive Neuromuscular Facilitation (PNF) stretching. The pain individual subjects perceived after stretching was measured via a Visual Analog Scale (VAS) and compared between the groups Results: Despite the decrease in the intensity of static stretching, no decrease in VAS value was observed. In PNF stretching, a significant decrease was observed at P50 compared to P100. S100 was significantly higher than P75 and P50. Conclusion: Previous studies have shown that PNF has a superior or the same effect on flexibility in comparison with static stretching. This effect was maintained even in moderate intensity. PNF stretching performed under moderate rather than high intensive static stretching, which causes pain and discomfort, might be recommended in clinical settings.

• Tuberculosis and Respiratory Diseases
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• v.42 no.3
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• pp.332-341
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• 1995

Background: Measurement of bronchodilator response is necessary to establish reversibility of airflow obstruction that was helpful to estimate the diagnosis, treatment, and prognosis in obstructive airway disease. An useful index should be able to detect the bronchodilator response more sensitively not related with degree of airflow obstruction and also be independent of initial $FEV_1$. Method: Sensitivities of bronchodilator response in each group classified by degree of airflow obstruction in $FEV_1$, FVC, $FEF_{25\sim75%}$, Isovolume $FEF_{25\sim75%}$, sGaw were studied and correlation coefficients were calculated between initial $FEV_1$ and reversibilities expressed as absolute, %initial, % predicted, %possible in $FEV_1$. Result: Sensitivities of bronchodilator response were 61.5% in FVC, Isovolume $FEF_{25\sim75%}$ and sGaw, in severe group, and 56.3% in Isovolume $FEF_{25\sim75%}$ and sGaw, in moderate group, and 62.5% in $FEV_1$ and sGaw and 50.0% in FVC and Isovolume $FEF_{25\sim75%}$, in mild group, and 60.0% in sGaw and 58.0% in Isovolume $FEF_{25\sim75%}$ in total patients. Correlation coefficients between initial $FEV_1$(L) and absolute, % initial, % predicted, % possible were 0.15, -0.22(p<0.05), 0.02, 0.24(p<0.05) and correlation coefficients between initial $FEV_1$(% predicted) and absolute, % initial, % predicted, %possible were 0.06, -0.28(p<0.05), 0.08, 0.39(p<0.05). Conclusion: Volume related parameters were more sensitive index not related with degree of airway obstruction and the change in $FEV_1$ expressed as % predicted was the least dependent on initial $FEV_1$ and reversibilities, expressed as % initial or as % possible(predicted minus initial $FEV_1$)were correlated with initial $FEV_1$.

• Journal of Animal Science and Technology
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• v.58 no.6
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• pp.19.1-19.7
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• 2016

Background: Cowpea (Vigna unguiculata [L.]) is a legume cultivated throughout most tropical countries and is valued as food and feed for human and livestock respectively. The search for an improved cowpea variety has been on-going with the aim of improving traits such as grain yield, drought and pest resistance. But no information exist on the feeding value of these improved varieties. Phosphate (P) fertilizer application is recommended to augment grain yield in grain legumes but data on the effect of P fertilizer on haulm quality is limited. Results: Two separate experiments were conducted to determine the effect of P fertilizer dose on the nutritive value of haulms from different cowpea varieties (V). In experiment 1, effect of three P doses (30, 60 and 90 kg $P_2O_5/ha$) on in vitro gas production (IVGP) characteristics, concentrations of digestible organic matter (DOM), crude protein (CP), acid detergent fiber (ADF) and neutral detergent fiber (NDF) of haulms from five cowpea varieties (Zaayura-SARC 4-75, Songotra-IT97K-499-35, Hewale-IT93K-192-4, IT99K 573-1-1 and Asomdwe-IT94K-410-2) were investigated using the $3(P){\times}5(V)$ factorial treatment arrangements in a completely randomized design. In experiment 2, the effects of two P doses (30 and 90 kg $P_2O_5/ha$) and two varieties (Zaayura-SARC 4-75 and Hewale-IT93K-192-4) on the voluntary feed intake, live weight, haematology and carcass characteristics of Djallonke lambs were also assessed using a $2(P){\times}2(V)$ factorial treatment arrangement. The $V{\times}P$ interaction significantly affected CP, NDF and ADF with CP concentration increasing with increase in P doses in Zaayura-SARC 4-75 and Asomdwe-IT94K-410-2. Whilst an increase (P < 0.05) in NDF was observed in Songotra-IT97K-499-35and Asomdwe-IT94K-410-2 as P doses increased, the other V only increased from P dose 30 to 60 kg/ha and declined at P dose 90 kg/ha. The ADF decreased (P < 0.05) with increase in P dose for all V with the exception of Songotra-IT97K-499-35. There was a significant V effect on DOM with the highest reported in Zaayura-SARC 4-75 (43.44 %). Daily DM intake, carcass length and blood urea nitrogen of the lambs were significantly affected by the V x P interaction. There was a significant V effect on globulin and P effect on live weight at slaughter, dressed weight, chuck, leg, loin, rib and flank and liver and lungs. Conclusion: It can be concluded that nutrient concentrations of cowpea haulms were positively influenced by different P dose and varieties with favorable effects on growth, haematology and carcass composition of lambs. Varieties Zaayura-SARC 4-75 and Hewale-IT93K-192-4 at P dose at 90 kg/ha are recommended to enhance growth performance and carcass yield of Djallonke lambs.

• The Journal of Korean Academy of Prosthodontics
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• v.41 no.2
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• pp.169-181
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• 2003

Statement of problem : The survival rate of wide diameter implants was lower than of 3.75-mm implants in some clinical researches. Purpose : The purpose of this study was to investigate the influence of implant diameter on the osseointegration of implants in the rabbit femoral condyle and tibial metaphyses by means of removal torque measurements and histomorphometric analysis. Material and Method : Ten adult New Zealand White rabbits were used in this study Two 3.75-mm diameter implants were inserted through one cortical layer in the tibial metaphyses and one 3.75-mm diameter implant was inserted in the femoral condyle. 5.0-mm diameter implants were inserted in the other leg in the same manner. A total of 60 implants (3.75-mm diameter implants:30 : 5.0-mm diameter implants:30) were installed. After a healing time of 4 and 12 weeks, the peak removal torque values required to shear off the implants were recorded. From the removal torque values (Ncm) obtained, the mean shear stress ($N/mm^2$) was calculated. And the percentage of direct bone-to-implant contact and the percentage of bone area inside the thread were measured by Kappa Image Base-metreo. The Student's t-test was undertaken for statistical analysis (p<0.05). Results : The removal torque value of 5.0-mm diameter implants was higher than of 3.75-mm diameter implants (p<0.05). The difference of shear stress value between 3.75-mm and 5.0-mm diameter implants was not statistically significant (p>0.05). The percentage direct bone-to-implant contact had no statistical difference between two groups (p>0.05). The percentage of bone area inside the thread had no statistical difference between two groups (p>0.05). Conclusion It is concluded that the quality f osseointegration is not influenced by increasing implant diameter.

• Journal of Nutrition and Health
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• v.28 no.9
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• pp.893-903
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• 1995

This study was attempted to estimate seasonal variations of physical activity level, energy balance & body composition of 38 rural women, aged 31 to 67yrs in three seasons ; farming season(June), harvesting season(October), nonfarming season(February) Energy intake, energy expenditure and body composition were assessed using questionnaire, daily activity diary & bioelectrical impedance. The type of activities & the period of the spent on each activity were changed significantly with the seasons. Daily mean duration(min) of farming activity was significantly higher in June & October than in February(p<0.005) & daily mean energy expenditure for farming activity was significantly high in June & low inFebruary (p<0.005). Daily mean energy expenditure was 2892.9㎉ in June, 2487.4㎉ in October and 2130.9㎉ in February and changed significantly in three seasons(p<0.005). Daily mean energy intake was significantly higher in June(=1950.3㎉) & October (=1946.9㎉) than in February(=1423.3㎉)(p<0.005). According to RDA for koreans, the level of physical activity fell into exceptional activity category in June, heavy in October, moderate in February. Mean energy balance was negative in all seasons ; 0.682 in June, 0.812 in October and 0.698 in February. In three seasons mean body weight, mean obesity rate and mean body mass index(BMI) were not changed significantly. But there were significant seasonal variations in body fat(%) & lean body mass(LBM)(%). The mean percentage of body fat(%) was within normal range(24.44-24.79%) & the mean percentage of lean body mass(LBM)(%) representing long term physical activity was significantly higher in June(75.56%) & October(75.21%) & October (75.21%) than in February(72.75%)(p<0.05).

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.6085-6088
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• 2013

Prostate specidic antigen (PSA) and digital rectal examination (DRE) are the known predictive factors for positive prostate biopsies differing according to the age, region and race. There have been only very limited studies about the impact of PSA on histological findings at prostate biopsy in Turkey. The aim of this study was to evaluate the impact of PSA and clinical stage on histologic findings of prostate biopsy in men older than 75 years of age as a first study in the Turkish population. A total of 1,645 consecutive prostate biopsies were included, with 194 men aged 75 or older. Cancer was identified in 104 patients (53.6%). Of the 104 positive biopsies, Gleason scores were less than 7 in 53 (49%) patients, 7 or greater in 51 (51%) patients. Positive prostate biopsies were significantly correlated with advanced age (p=0.0001), abnormal DRE (p=0.0001) and raised PSA (p=0.0001). The prostate volume was significantly correlated with advanced age especially in prostate cancer patients over 75 years, compared with those under 75 (p=0.0001). These results are useful for counseling men older than 75 years for prostate cancer detection. However, PCa screening decisions are currently based on urologist judgment and detection of latent asymptomatic disease is an important concern regarding costs, overdiagnosis, overtreatment and quality of life (QOL) for men aged 75 years and older. Healthy old patients with a long life expectancy need to be carefully evaluated for eligibility for PCa screening.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.4
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• pp.111-117
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• 2007

The visual evoke potential(VEP) is the effective method to diagnose and treat the amblyopia or to check the infants visual ability. In order to evaluate the changes of P100 latencies and amplitudes of VEP by intensity of illumination and refractive errors, we measured latencies and amplitudes of 41 normal adults (20/20 VA) who have no ocular diseases and neurologic diseases. The results were as follows: In the scotopic condition, the latencies were N75$75.83{\pm}3.69$ msec, P100$103.48{\pm}5.34$ msec, the P100 amplitude was $14.86{\pm}2.43$ msec, and in the photopic condition, the latencies were N75$76.71{\pm}3.11$ msec, P100$107.26{\pm}5.54$ msec and the P100 amplitude was $10.35{\pm}1.75$ msec. The latencies and amplitudes of P100 in the photopic condition had higher values than those in the scotopic condition and the measures were significantly different between the scotopic and photopic condition (p<0.01). The P100 latencies were delayed both in the scotopic and photopic condition with the refractive errors and those measures were delayed more than in the photopic condition. The P100 amplitudes in the induced myopic and hyperopic conditionsreduced than in the emmetopes in both illumination conditions. The P100 latencies and amplitudes in emmetropes showed a correlation with the induced myopic conditions in the scotopic condition. Those results showed that P100 latencies and amplitudes are dependent on the illumination conditions and refractive errors. And we suggest that those results would be useful to determine and evaluate the normal range for the person considering patients' refractive errors and illumination of the test room.