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Dosimetric Comparison between Varian Halcyon Analytical Anisotropic Algorithm and Acuros XB Algorithm for Planning of RapidArc Radiotherapy of Cervical Carcinoma

  • Mbewe, Jonathan;Shiba, Sakhele
    • Progress in Medical Physics
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    • v.32 no.4
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    • pp.130-136
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    • 2021
  • Purpose: The Halcyon radiotherapy platform at Groote Schuur Hospital was delivered with a factory-configured analytical anisotropic algorithm (AAA) beam model for dose calculation. In a recent system upgrade, the Acuros XB (AXB) algorithm was installed. Both algorithms adopt fundamentally different approaches to dose calculation. This study aimed to compare the dose distributions of cervical carcinoma RapidArc plans calculated using both algorithms. Methods: A total of 15 plans previously calculated using the AAA were retrieved and recalculated using the AXB algorithm. Comparisons were performed using the planning target volume (PTV) maximum (max) and minimum (min) doses, D95%, D98%, D50%, D2%, homogeneity index (HI), and conformity index (CI). The mean and max doses and D2% were compared for the bladder, bowel, and femoral heads. Results: The AAA calculated slightly higher targets, D98%, D95%, D50%, and CI, than the AXB algorithm (44.49 Gy vs. 44.32 Gy, P=0.129; 44.87 Gy vs. 44.70 Gy, P=0.089; 46.00 Gy vs. 45.98 Gy, P=0.154; and 0.51 vs. 0.50, P=0.200, respectively). For target min dose, D2%, max dose, and HI, the AAA scored lower than the AXB algorithm (41.24 Gy vs. 41.30 Gy, P=0.902; 47.34 Gy vs. 47.75 Gy, P<0.001; 48.62 Gy vs. 50.14 Gy, P<0.001; and 0.06 vs. 0.07, P=0.002, respectively). For bladder, bowel, and left and right femurs, the AAA calculated higher mean and max doses. Conclusions: Statistically significant differences were observed for PTV D2%, max dose, HI, and bowel max dose (P>0.05).

The Optimal Condition and Enzyme Activity of Entomopathogenic Fungus Beauveria bassiana Using Extracted Rice Bran (미강추출물을 이용한 곤충병원성 곰팡이 Beauveria bassiana의 최적 배양조건 및 효소활성)

  • Kim, Chang-Su;Lee, Jung-Bok;Kim, Beam-Soo;Lee, Min-Hye;Kang, Kyeong-Muk;Joo, Woo-Hong;Kim, Jin-Won;Im, Dae-Joon;Kwon, Gi-Seok
    • Journal of Life Science
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    • v.23 no.8
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    • pp.1010-1018
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    • 2013
  • The greenhouse whitefly, Bemisia tabaci, is considered one of the most destructive pests of crops. In this study, we aimed to determine the optimal liquid culture conditions in shake flasks for maximal sporulation of Beauveria bassiana M130 using rice bran. The optimal initial pH for the spore production of B. bassiana using extracted rice bran medium was 5.2 and $28^{\circ}C$. The screening in shake flasks of carbon and nitrogen sources resulted in the identification of an optimal medium based on 0.5% $(NH_4)_2SO_4$, with extracted rice bran 8:1. Using this medium, a production level of $2.15{\times}10^9$ spores per ml was obtained after six days from culture inoculation at $28^{\circ}C$ in a rotary shaking incubator at 130 rpm. In addition, the specific activities of extracellular enzymes of chitinase and protease were $4,296{\mu}mol$ and $375{\mu}mol$, respectively. These results suggest that Beauveria bassiana M130 could be a bio-controller for the greenhouse whitefly.

A Study on Compensation for Imaging Qualities Having Artifact with the Change of the Center Frequency Adjustment and Transmission Gain Values at 1.5 Tesla MRI (1.5 Tesla 기기에서 중심주파수 조정과 송 신호강도(Transmission Gain)값 변화에 따른 인공물이 있는 자기공명영상의 질 보상에 관한 연구)

  • Lee, Jae-Seung;Goo, Eun-Hoe;Park, Cheol-Soo;Lee, Sun-Yeob;Lee, Han-Joo
    • Progress in Medical Physics
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    • v.20 no.4
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    • pp.244-252
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    • 2009
  • The purpose of this study is to compensate for susceptibility and a ferromagnetic body artifact using CFA and TGV on MR Imaging. A total of 30 patients (15 men and 15 women, mean age: 45 years) were performed on head and neck diseases. MR Unit used a 1.5T superconducting magnet (GE medical system, High Density). This study have investigated by changing with CFA and TGV (70, 90, 110, 130, 150) searching for compensation values about susceptibility and a ferromagnetic body artifact in 60 kg standards of body weight (p<0.05). As a quality results, Image qualities were obtained at different score from CFA and TGV (70, 90, 110, 130, $150=3.23{\pm}0.35$, $4.31{\pm}0.02$ $4.23{\pm}0.21$, $5.12{\pm}0.25$, $7.13{\pm}0.72$, $8.31{\pm}0.01$, $5.21{\pm}0.15$, $6.14{\pm}0.08$, $5.23{\pm}0.72$, $5.91{\pm}0.06$, p<0.05). Absolute CNRs (TG, CNRpre, CNRpost) were acquired with (70:$-1.44{\pm}0.11$, $-2.7{\pm}0.04$, 90:$-2.18{\pm}0.42$, $-4.41{\pm}0.43$, 110:$-2.89{\pm}0.43$, $-5.23{\pm}0.02$, 130:$-2.34{\pm}0.05$, $-5.26{\pm}0.01$, 150: $-2.09{\pm}0.08$, $-3.87{\pm}0.12$, p<0.05). In conclusions, this study could be compensated for metal and flow artifacts surrounding the tissues having artifact by changing CFA and TGV.

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Effects of Weekly Administration of Implant-type Recombinant Porcine Somatotropin on the Performance and Carcass Characteristics of Finishing Pigs

  • Kim, Y.H.;Jung, H.J.;Park, J.C.;Kwon, O.S.;Chung, C.S.;Ko, Y.D.;Moon, H.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.4
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    • pp.557-561
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    • 2005
  • The present study was undertaken to investigate the effects of weekly administration of implant type recombinant porcine somatotropin (rpST) on the performance and carcass characteristics in finishing pigs. A total of 120 crossbred (Landrace${\times}$Yorkshire${\times}$Duroc) pigs were employed for 11 weeks in a growth trial in experiment. A rpST designed to implant every 7 d was used. Forty pigs, each weighing 75 kg, were allocated into three rpST treatments; control (CONT), implant of rpST from 75 kg (TRT1) or 90 kg (TRT2) of body weight. The CONT pig and pigs in TRT2 from 75 kg to 90 kg were treated without rpST but with placebo. In rpST-treated pigs, each 100 mg and 125 mg of the equivalent rpST was implanted from live weight of 75 kg to 90 kg and from 90 kg to market weight, respectively. Half of the pigs from each treatment were marketed at live weight of 110 kg and the rest at 130 kg. All pigs were allowed ad libitum access to a commercial feed containing 0.94% and 0.88% of lysine from 75 to 110 kg, 110 to 130 kg of body weights, respectively. rpST had no effect on daily gain, while feed efficiency was improved by 7 to 13% (p<0.05) in the rpST-treated groups compared with the CONT. Compared with the CONT, backfat thickness was decreased by 12% (p<0.05) in TRT1 at 110 kg of market weight, and by 23 to 32% (p<0.05) in the rpST-treated groups at 130 kg of market weight, respectively. Lean muscle rate tended to be higher in TRT1 at both 110 kg and 130 kg of market weight, and carcass fat percentage in the rpST-treated groups was decreased by 33 to 46% (p<0.05) compared with the CONT.

Surface Properties of Mercaptopyruvic-acid Layer Formed on Gold Surfaces Interacting with ZrO2 (지르코니아와 상호작용하는 금 표면 위의 메르캡토파이러빅산층 표면 물성)

  • Park, Jin-Won
    • Clean Technology
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    • v.20 no.2
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    • pp.130-135
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    • 2014
  • It is investigated that the surface properties of mercaptopyruvic-acid layer formed on gold surfaces may make an effect on the distribution of either gold particle adsorbed to the zirconia surface or vice versa. For the investigation, the atomic force microscope was used to measure the surface forces between the surfaces as a function of the salt concentration and pH value. The forces were quantitatively analyzed with the derjaguin-landau-verwey-overbeek (DLVO) theory to estimate the electrostatic properties, potential and charge density, of the surfaces for each condition of salt concentration and pH value. The estimatedvalue dependence on the salt concentration was explained with the law of mass action, and the pH dependence was interpreted with the ionizable groups on the surface. The salt concentration dependence of the surface properties, found from the measurement at pH 4 and 8, was predictable from the law. It was found that the mercaptopyruvic-acid layer had higher values for the surface charge densities and potentials than the zirconia surfaces at pH 4 and 8, which may be attributed to the ionizedfunctional-groups of the mercaptopyruvic-acid layer.

On-Line Social Network Generation Model (온라인 소셜 네트워크 생성 모델)

  • Lee, Kang-Won
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.24 no.7
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    • pp.914-924
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    • 2020
  • In this study we developed artificial network generation model, which can generate on-line social network. The suggested model can represent not only scale-free and small-world properties, but also can produce networks with various values of topological characteristics through controlling two input parameters. For this purpose, two parameter K and P are introduced, K for controlling the strength of preferential attachment and P for controlling clustering coefficient. It is found out on-line social network can be generated with the combinations of K(0~10) and P(0.3~0.5) or K=0 and P=0.9. Under these combinations of P and K small-world and scale-free properties are well represented. Node degree distribution follows power-law. Clustering coefficients are between 0.130 and 0.238, and average shortest path distance between 5.641 and 5.985. It is also found that on-line social network properties are maintained as network node size increases from 5,000 to 10,000.

Morava K- theory of the double loop spaces of quaternionic stieffel manifolds

  • Park, Younggi
    • Bulletin of the Korean Mathematical Society
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    • v.34 no.3
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    • pp.359-370
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    • 1997
  • In this paper we get the Morava K-theory of the double loop spaces of quarternionic Stiefel manifolds for an odd prime p by computing the Atiyah - Hirzebruch spectral sequence. We also get the homology with Z/(p) coefficients and analyze p torsion in the homology with Z coefficients.

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Development and Educational Effect of Nutrition Education Workbook for Improvement of Child Picky Eaters - Focused on 2nd and 3rd Graders - (편식개선을 위한 초등학생 영양교육 교재 개발 및 교육 효과 - 초등학교 2, 3학년 중심으로 -)

  • Woo, Tae-Jung;Ji, Youn-Jeong;Lee, Kyung-Hea
    • Journal of the Korean Dietetic Association
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    • v.17 no.2
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    • pp.130-141
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    • 2011
  • This study was conducted to develop a nutrition education workbook to improve picky eating in children and to evaluate the effect of nutrition education using this developed workbook. The developed workbook focused on 2nd and 3rd grade students and consisted of five units. The contents included: multi-grain, vegetables (2 units), fish, and milk. The activities, including observation, and learning the roles and names of the foods, were developed mainly to increase motivation for eating a balanced diet. This workbook was developed from April to December 2008, and was applied at 15 elementary schools containing 1,674 students from April to September 2009 in Changwon City, Korea. We evaluated changes in knowledge before and after education on nutrition, eating behavior, dietary habits, and educational activities using self-administered questionnaires. The children demonstrated significant improvements in nutritional knowledge (P<0.001), eating behavior (P<0.001), and dietary habits (P<0.001). Most of the children answered that the education program was helpful and exciting. Based on these results, we believe that the developed workbook is suitable for children picky eaters, and hope it will be used in the field of child nutrition education.

Analysis of Biomechanical Characteristics of Therapist's Ground Reaction and Contact Hand Force and Time According to Table Height During Spinal Manipulation

  • Jejeong Lee;Yongwoo Lee
    • Physical Therapy Rehabilitation Science
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    • v.12 no.2
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    • pp.130-139
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    • 2023
  • Objective: This study aimed to analyze the effects and characteristics of the height of the treatment table on the force and time of ground reaction (GR) and contact hand (CH) generated from the therapist's feet to generate thrust during spinal manipulation (SM). Design: A cross-sectional survey study Methods: Thirty-six healthy subjects were recruited. SM was performed on the ilium using a knee-high table, where the therapist felt it was easy to control the subject's posture and body shape and comfortable to generate force, as well as a relatively high thigh-high table. The force and time generated by the therapist's GR and CH were simultaneously measured through a force plate. Results: As a result, there was a significant difference in peak force and rundown force at the therapist's GR according to the table height (p < 0.05). In the therapist's CH, there was a significant difference between PreMin (preload minimum) force and peak force (p < 0.05), and there was a significant difference between the time from PreMin to peak and the time of the entire section (p < 0.05). Conclusions: As a result, the generation of increased CH force and faster thrust duration were confirmed by mobilizing the reduced GR force of the therapist to generate thrust than the relatively high table on the knee-high table.

Effects of Seasonal Wiring Treatments on Fruit Quality, Carbohydrates, and Mineral Nutrients of 'Niitaka' (Pyrus pyrifolia Nakai) Pear Trees (시기별 Wiring 처리가 '신고' 배의 과실품질 및 수체 내 탄수화물과 무기성분에 미치는 영향)

  • Seo, In-Ho;Song, Jang-Hoon;Seo, Ho-Jin
    • Korean Journal of Organic Agriculture
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    • v.27 no.1
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    • pp.33-44
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    • 2019
  • This study was initiated to find possibility of substitute of gibberellin acid and to prevent negative girdling effect such as slow growth of 'Niitaka' (Pyrus pyrifolia Nakai) trees, a major pear cultivar, at harvest and at 60-, 90-, and 120-d after storage. Seasonal wiring with 3.0-mm-diameter were applied on the main branch at 70, 80, 90, 110, and 130 days after full bloom (DAF) to compare the fruit quality and storability. Fruit weight and sugar contents were the greatly increased by the wiring treatment at 110 DAF, with the lowest values observed for the wiring at 70 DAF. All the wiring treatments reduced fruit acidity but did not affect fruit firmness. a-value on fruit skin was the highest for wiring at 110 DAF and 130 DAF, advancing fruit ripening. The lowest fruit weight loss was occurred at wiring at 110 DAF. a-value on fruit skin was the highest for wiring at 90 DAF and 110 DAF. Wiring at 80 DAF the most increased floral bud diameter, resulting in the lowest L:D ratio of 1.74 observed. As for the mineral nutrients concentrations of floral buds, the concentration of K (0.63%) and Mg (0.31%) were the highest after 80 DAF wiring treatment, whereas Ca and P concentrations did not differ among treatment plots. The leaf K concentrations was the highest in the 130-day wiring treatment (0.76%) and in the control plot (0.78%), whereas there was no significant difference in the concentrations of either Ca or P among treatment plots. Short periods of wiring increased foliar Mg concentrations. In floral buds, carbohydrates showed a tendency for accumulating at a lower concentrations (7.75%) after 70 DAF wiring treatment, which was a relatively short treatment period. On the other hand, the carbohydrate concentrations in leaves showed a tendency for accumulating at lower concentrations after 130 DAF wiring treatment (2.51%), which is a long treatment period, and in the control plot (2.43%). Wiring increased the size and sugar content of fruits, and influenced fruit storability. For the wiring treatment period was delayed, the carbohydrate concentration in flower buds showed curvilinear correlation and the negative correlation with the carbohydrate in leaf tissue.