• Korean Journal of Food Science and Technology
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• v.37 no.5
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• pp.806-811
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• 2005

Effects of green tea-soybean paste on weight-changes and serum lipid profiles in rats fed high fat diet were investigated. Sprague-Barley male rats divided into five groups were fed five different diets for 10 weeks: B group, basal diet H group, high fat-diet containing 0.5% cholesterol+15% lard H-S group, high fat diet containing soybean paste H-0.6GS group, high fat diet containing 0.6% green tea-soybean paste H-4GS group, high fat diet containing 4% green tea-soybean paste. H group showed highest weight gain (p<0.05). Addition of green-tea soybean paste to high-fat diet significantly decreased weight gain, H-4GS group showing highest weight loss (p<0.05). No significant differences in food efficiency ratio and total food intake were found among groups. Liver weight of H group was highest. Addition of green tea-soybean paste to high fat diet significantly reduced liver weight (p<0.05, Table 2). Concentrations of glucose, uric acid, bilirubin, and total protein were similar among all group. Mean GPT values of H-4GS group were significantly different from these of H- and H-S groups (p<0.05). H-S, H-0.6GS, and H-4GS groups had significantly lower triglyceride and total cholesterol, and higher HDL than H-group (p<0,05). H-4GS group had significantly lower serum triglyceride than H-0.6GS group (p<0.05).

• Journal of Veterinary Clinics
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• v.14 no.2
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• pp.308-318
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• 1997

The present experiment was performed in order to know the treatment effect of aquapuncture with hepatonics on recovery in artificially induced hepatic damaged dogs by carbon tetrachloride. The animals were divided into a control and two experimental groups (aquapuncture with taurine into Gan-su acupoint: Aa-I group and aquapuncture with taurine into blank acupoint in the thigh: Aa-II group). The changes of serum enzyme activities (ALT, AST and ALP), serum total protein contents, protein fractions and pathohistological findings of the liver were examined after application of aquapunctiuf treauent The results obtained through this experiment were summarized as follows : The serum ALT activities tendeded to decrease in experimental group compared with those of control group. Significances were detected at 5th (p<0.05) and 7th (p<0.05) day in Aa-I group and 7th day (p<0.05) in Aa-II group, respectively. Low value was fecund in Aa-I group compared with Aa-II groups but significance was not observed between two experimental groups. The serum AST activities in experimental group showed decreasing tendency compared with those of control group. Significances were observed at 2nd (p<0.05) and 5th (p<0.05) day in Aa-I group and 2nd (p<0.05) day in Aa-II groups respectively. Aa-I group showed lower values than those of Aa-II groups however, no significance was detected between experimental groups. The serum ALP activities of experimental group showed a slight decrease compared with those of control group, however, significance was not detected among all groups. The serum total protein content in experimental group showed tendency of increase compared with control group. Significance was found at 2nd day (p<0.05) in Aa-I group, but there was no significance in Aa-II group. Further significant increase of total protein content was seen at 1st day (p<0.05) in Aa-I group compared with Aa-II group. The change of serum albumin content in experimental group showed tendency of increase compared with control. Significant increases were detected at 1st (p<0.01) and 2nd (p<0.01) day in Aa-I group, respectively. Aa-II group showed increase compared with control groups but significance was not observed. Further significant increase was at 1st day (p <0.05) in Aa-I group compared with Aa-II group. The change of ${\beta} $-globulin in Aa-I group was slightly decreased compared with control group. Aa-II group was similar to controls but significance was not observed among all groups. The change of P-globulin content in Aa-I group showed tendency of increase compared with control and Aa-II group showed the tendency of decrease compared with control. The change of ${\gamma}$-globulin content experimental group showed tendency of increase compared with control, however, significance was not detected among groups. The change of A/G ratio in Aa-I group showed tendency of increase compared with control group and Aa-II group was similar to controls but no significance was found among groups. As for pathohistological observations the grade of hepatocellular vacuolized degeneration and necrosis in Aa-I group was milder than those of control and Aa-II groups and the change of Aa-II group was similar to that of control. Considering above finding collectively, it was thought that aquapuncture of Gan-su acupoint with hepatonics was more effective than aquapuncture of blank acupoint for the recovery of hepatic damage.

• Journal of Korean Academy of Nursing
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• v.45 no.3
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• pp.459-468
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• 2015

Purpose: The purpose of this study was to investigate the effects of Wheel of Wellness counseling on wellness lifestyle, depression, and health-related quality of life in community dwelling elderly people. Methods: A parallel, randomized controlled, open label, trial was conducted. Ninety-three elderly people in a senior welfare center were randomly assigned to two groups: 1) A Wheel of Wellness counseling intervention group (n=49) and 2) a no-treatment control group (n=44). Wheel of Wellness counseling consisted of structured, individual counseling based on the Wheel of Wellness model and provided once a week for four weeks. Wellness lifestyle, depression, and health-related quality of life were assessed pre-and post-test in both groups. Results: Data from 89 participants were analyzed. For participants in the experimental group, there was a significant improvement on all of the wellness-lifestyle subtasks except realistic beliefs. Perceived wellness and depression significantly improved after the in the experimental group (n=43) compared to the control group (n=46) from pre- to post-test in the areas of sense of control (p =.033), nutrition (p =.017), exercise (p =.039), self-care (p <.001), stress management (p =.017), work (p =.011), perceived wellness (p =.019), and depression (p =.031). One participant in the intervention group discontinued the intervention due to hospitalization and three in the control group discontinued the sessions. Conclusions: Wheel of Wellness counseling was beneficial in enhancing wellness for the community-dwelling elderly people. Research into long-term effects of the intervention and health outcomes is recommended.

• Research in Community and Public Health Nursing
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• v.31 no.1
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• pp.65-75
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• 2020

Purpose: The purpose of this study was to identify the effect of regular Nordic walking exercise on the physical indicators and subjective happiness of middle-aged rural residents. Methods: A pretest and posttest design with a non-equivalent control group was conducted. The participants of experimental and control group were each 21 subjects from 40 to 64 years old. The Nordic walking exercise program consisted of 24 sessions which were focused on group exercise, and was conducted three times a week for eight weeks. Results: The experimental group showed significant decreases in body mass index (p=.042), body fat (p<.001), and abdominal fat (p=.026). The experimental group showed significant increases in muscle mass of right lower limb (p=.009) and left lower limb (p=.016) but was not statistically significant in right, left upper limbs and body. On the other hand, the control group showed significant decreases in muscle mass of right upper limb (p=.034), left upper limb (p=.038), and body (p=.034). There were no significant differences in systolic blood pressure, diastolic blood pressure, and subjective happiness between the experimental and the control group. Conclusion: The Nordic walking exercise should be actively encouraged to improve health of the middle-aged in rural area.

• Journal of the Korean Geotechnical Society
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• v.18 no.1
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• pp.127-132
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• 2002

Shaking table tests are performed on model group piles to investigate the mechanics of dynamic pile-soil interaction, and to evaluate the dynamic group pile effect. Tests are executed on a single pile as well as group piles($3\times3$) by varying a pile spacing from 3D to 8D. A lumped mass is located on top of piles to simulate a superstructure. Dynamic p-y curves of the single pile and the group piles are obtained from the tests and compared with the backbone slopes of API cyclic p-y curves. From the comparisons, dynamic pile group effects are evaluated in terms of a pile spacing, a shaking frequency, and a shaking intensity.

• The Journal of Korean Academic Society of Nursing Education
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• v.5 no.2
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• pp.300-314
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• 1999

This study is an attempt to evaluate the effect of the medication and symptoms self-care education on the psychiatric patients' quality of life. This exploratory study was designed to a quasi-experiment of pretest-postest with a non equivalent control group. Subjects of 40 patients who were discharged from a mental hospital in Pusan were selected to be experiment and control group, with each group consisting of 20. The research period was from March, 6 to May, 29, 1999 and the pre-post test was given before and after implementing MSSE to the both experiment and control group. The results finding were summarized as follows ; 1. subjects who attended self-care education scored significantly higher than control group in quality of life.(Z=-2.06, P=0.034) 2. Those who were in the experiment group reported more significant higher scores than control group in item of quality of life, living situation(A=-2.62 P=0.012), relations with spouse (Z=-2.31 P=0.038) and children (Z=3.37, P=0.008), fear (Z=-1 95, P=0.049) and anger(Z=-2.07 P=0.041), work functioning (Z=-2.34, P=0.021), environmental adjustment. (Z=-2.05, P=0.039)

• Journal of the korean academy of Pediatric Dentistry
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• v.25 no.3
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• pp.483-492
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• 1998

To investigate the prevalence and etiologic factors of nursing caries, oral examination was performed on 1,100 kindergarten children from 6 Seoul areas and 3 Hongchun areas. Parents were asked to fill out questionnaires. The following results were obtained: 1. The prevalence of nursing caries among 1,100 in the sample group(age 30-75 months) was 14.8%. 2. Fathers' education level(p<0.05), mothers' education level(p<0.01) and monthly income was higher in caries-free group children. 3. When the dietary tendencies of nursing caries group and caries-free group were compared, no significant differences in the length and method of feeding were found. However, nursing caries group showed higher frequency of bedtime nursing habit(p<0.01), daytime use of bottle as a comforter(p<0.01) and other beverage feeding in addition to milk(p<0.01). 4. When the parents' awareness of caries prevention was compared, caries-free group per formed more frequent tooth cleansing(p<0.05) and periodic dental examination(p<0.01).5. Dental caries experience of mothers was significantly lower in the caries free group(p<0.05). From the above results, it can be concluded that deleterious nursing habit had great effect on developing nursing caries and the incidence of nursing caries was lower among children with parents of higher socioeconomic status.

• Journal of Acupuncture Research
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• v.39 no.4
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• pp.304-309
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• 2022

Background: This study was conducted to determine the anti-inflammatory effect of astaxanthin, on atopic dermatitis. Methods: Changes in mouse body weight, lymph node weight, and the degree of improvement in symptoms were measured to determine the inflammatory response. Real-time reverse transcription-polymerase chain reaction tests were performed to determine the degree of expression of inflammation-related cytokines (IL-31 and IL-33 and chemokines such as CCL17 and CCL22), and western blot analysis was performed to evaluate the expression of inflammation-related factors (iNOS, COX-2, and NF-kB signaling molecules p-IkBα, p50, p-65 and pSTAT3). Results: The degree of symptoms significantly improved in the PA+AX group. Lymph node weight in the PA+AX group was lower than the PA group. Inflammatory cytokines (IL-31, IL-33, and inflammatory chemokines such as CCL17 and CCL22) were significantly reduced in the PA+AX group compared with the PA group. The expression of inflammatory genes (iNOS, COX-2, NF-kB and signaling molecules (p-IkBα, p50, p65, and p-STAT 3) was lower in the PA+AX group compared with the PA group. Conclusion: Astaxanthin may modulate the inflammatory response in a mouse model of atopic dermatitis and has an anti-inflammatory effect.

• Nutrition Research and Practice
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• v.7 no.1
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• pp.26-33
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• 2013

The effect of lycopene supplementation on the antioxidant system was investigated by analyzing lipid peroxide levels, glutathione contents, and antioxidant enzyme activities in Mongolian gerbils fed a high fat diet. Gerbils were fed on each experimental diet for 6 weeks; normal diet (NC), normal diet with 0.05% lycopene (NL), high fat diet (HF), and a high fat diet with 0.05% lycopene (HFL). Dietary supplementation of lycopene increased hepatic lycopene level in gerbils fed a normal or high fat diet (P < 0.05). Liver and erythrocyte concentrations of lipid peroxide increased in gerbils fed a high fat diet, whereas lycopene supplementation decreased liver and erythrocyte concentrations of lipid peroxide (P < 0.05). Hepatic total glutathione content was higher in the NL group than that in the NC group (P < 0.05). Total antioxidant status in plasma increased following lycopene supplementation compared with that of the non-lycopene supplemented groups (P < 0.05). Hepatic catalase activity increased following dietary lycopene supplementation (P < 0.05). Superoxide dismutase activity in liver remained unchanged with lycopene supplementation, but erythrocyte superoxide dismutase activity increased in NL group compared with NC group (P < 0.05). Glutathione-S-transferase activity increased in the NL group compared to NC group (P < 0.05). Liver and erythrocyte glutathione peroxidase activity increased significantly in the NL group compared to that in the HF group (P < 0.05). Liver glutathione reductase activity was higher in the NL group than that in the NC group (P < 0.05). These results suggest that lycopene supplementation may be efficient for preventing chronic diseases induced by oxidative stress related to high fat diet.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.8
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• pp.1187-1193
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• 2015

This study determined the effects of dietary restriction on growth and the expression of lipid metabolism and growth hormone signaling genes in the longissimus dorsi muscle (LM) of Korean cattle. Thirty-one Korean cattle steers (average age 10.5 months) were allocated to normal (N; n = 16) or dietary restriction (DR; n = 15) groups. The feeding trial consisted of two stages: for the 8-month growing period, the DR group was fed 80% of the food intake of the normal diet, and for the 6-month growth-finishing period, the DR group was fed a DR total mixed ration with 78.4% of the crude protein and 64% of the net energy for gain of the normal diet. The LM was biopsied 5 months (period 1 [P1] at 15.5 months of age) and 14 months (period 2 [P2] at 24.5 months of age) after the start of feeding. The mRNA levels were determined using real-time polymerase chain reaction. Body weight, daily feed intake, average daily gain, and feed efficiency were lower in the DR group compared with the normal group at both P1 and P2. At P1, the lipogenic fatty acid synthase (FASN) mRNA levels were lower (p<0.05) in the DR group compared with the normal group. The DR group tended (p = 0.06) to have higher of levels of growth hormone receptor (GHR) mRNA than the normal group. At P2, the DR group tended to have lower (p = 0.06) androgen receptor (AR) mRNA levels than the normal group. In conclusion, our results demonstrate that dietary restriction partially decreases the transcription of lipogenic FASN and growth hormone signaling AR genes, but increases transcription of the GHR gene. These changes in gene transcription might affect body fat accumulation and the growth of the animals.