• Title/Summary/Keyword: oxygen administration

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The Effect of Oxygen Administration on Cerebrum Lateralization in Verbal Task (언어 과제 수행 시 산소 공급이 대뇌 편측화에 미치는 영향)

  • 정순철;김익현;김승철;손진훈
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 2003.11a
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    • pp.81-83
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    • 2003
  • The present study attempted to observe what changes the supply of highly concentrated(30%) oxygen cause to people's ability and cerebrum lateralization of verbal cognition, compared to air of normal oxygen concentration(21%). The experiment consisted of two runs, one for verbal cognition test with normal air(21% of oxygen) and for verbal cognition test with more oxygen in the air(30% of oxygen). Functional brain images were taken form 3T MRI using the single-shot EPI method. There were more activations observed at the occipital, parietal, temporal, and frontal lobes, but there were no changes in cerebrum lateralization with 30% oxygen administration. The result of task performance showed the accuracy increased at 30%'s concentration of oxygen rather than 21%'s. It is concluded that the positive effect on the verbal cognitive performance level by the highly concentrated oxygen administration was due to changeless increase of left and right cerebrum activation.

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The Effect of Highly Concentrated Oxygen Administration on Cerebrum Lateralization of Young Men during Visuospatial Task (고농도의 산소 공급이 공간지각 과제 수행 시 젊은 성인 남자의 대뇌 편측화에 미치는 영향)

  • 정순철;손진훈;김익현
    • Journal of the Korean Society for Precision Engineering
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    • v.21 no.8
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    • pp.180-187
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    • 2004
  • The present study attempted to investigate the effects of supply of highly concentrated (30%) oxygen on human ability of visuospatial cognition and cerebrum lateralization. compared to air of normal oxygen concentration (21%). The experiment consisted of two runs, one fur visuospatial cognition test with normal air (21% of oxygen) and for visuospatial cognition test with more oxygen in the air (30% of oxygen). Each run was composed of four blocks and each block included eight control tasks and five visuospatial tasks. Functional brain images were taken from 3T MRI using the single-shot EPI method. The result of task performance showed the accuracy increased at 30%'s concentration of oxygen rather than 21%'s. There were more activations observed at the left and right hemisphere, but there was decrease cerebrum lateralization with 30% oxygen administration. Thus, it is concluded that the positive effect on the visuospatial cognitive performance level by the highly concentrated oxygen administration was due to increase of cerebrum activation and decrease of cerebrum lateralization

Changes in Verbal Cognitive Performance, Blood Oxygen Saturation and Heart Rate due to 30% Oxygen Administration (30% 산소 공급에 의한 언어 인지 능력, 혈중 산소 농도, 심박동율의 변화)

  • Chung Soon Cheol;Sohn Jin Hun;Tack Gye Rae;Yi Jeong Han
    • Journal of the Korean Society for Precision Engineering
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    • v.22 no.4
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    • pp.173-180
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    • 2005
  • In this study, changes in verbal cognitive performance, blood oxygen saturation and heart rate due to 30% concentration oxygen supply were observed. Five male (24.6±0.9) and five female (22.2±1.9) college students were asked to perform 28 verbal cognitive tasks of the same difficulty during two types of oxygen (concentration 21%, 30%) administration. The experimental sequence consisted of Rest1 (1 min.), Control (1 min.), Task (4 min.), and Rest2 (4 min.) and the physiological signals such as blood oxygen saturation and heart rate were measured throughout the stages. The experimental result showed that the performance increased significantly at 30%'s concentration of oxygen rather than 21%'s, which shows oxygen supply has positive influence on verbal cognitive performance. When 30% concentration oxygen is supplied, the oxygen saturation in the blood significantly increased comparing to 21%. The heart rate showed no significant difference. Significant correlations were found between changes in oxygen saturation and cognitive performance. It is suggested that 30% oxygen can stimulate brain activation by increasing actual blood oxygen concentration in the process of cognitive performance.

Visuospatial Cognitive Performance, Hyperoxia and Heart Rate due to Oxygen Administration (산소 공급으로 유발된 공간 인지 능력, 혈중 산소 농도, 심박동율의 변화)

  • Chung Soon Cheol;Shon Jin Hun;Lee Bongsoo;Lee Soo Yeol
    • Journal of the Korean Society for Precision Engineering
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    • v.22 no.1
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    • pp.193-198
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    • 2005
  • Changes in visuospatial cognitive performance, blood oxygen saturation and heart rate due to the highly concentrated oxygen administration were observed in this study. Six male ($25.8 \pm$1.0) and six female (($23.8 \pm$ 1.9) adults were asked to perform 20 visuospatial tasks with the same level of difficulties by supplying two different oxygen levels (21%, 30%). Experiment consisted of Rest1 (1 min.), Control (1 min.), Task (4 min.), and Rest2 (4 min.) and physiological signals such as blood oxygen saturation and heart rate were measured through each stage. The result showed the accuracy of task performance increased significantly at 30% oxygen concentration compared with 21%, which means oxygen supply has positive effects on visuospatial cognitive performance. When 30% oxygen was supplied, blood oxygen saturation during control and task phases was increased and heart rate was decreased compared with 21%. It means that 30% oxygen can stimulate brain activities by directly increasing the actual level of blood oxygen concentration during cognitive performance, and enough oxygen supply during cognitive performance make heart rate decrease.

An fMRI Study of Cognitive Function during Hyperoxia

  • Chung Soon-Cheol;Kim Ik-Hyeon;Tack Gye-Rae;Lee Soo Yeol;Sohn Jin-Hun
    • Journal of Biomedical Engineering Research
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    • v.26 no.1
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    • pp.1-7
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    • 2005
  • This study aimed to investigate the hypothesis that administration of the air with 30% oxygen compared with normal air (21% oxygen) enhances cognitive functioning through increased activation in the brain. Seventeen college students (right­handed, average age of 24.3) were selected as subjects for this study. An oxygen supply equipment that provides 21% and 30% oxygen at a constant rate of 8L/min was developed. In order to measure the performance level of visuospatial and verbal cognition, two psychological tests were developed. The experiment consisted of two runs, one for cognition task with normal air (21% oxygen) and the other for cognition task with hyperoxic air (30% oxygen). Visuospatial and verbal tasks were presented while brain images were scanned by a 3T fMRI system using the single-shot EPI method. The results showed that there was an improvement in performance and also increased activation in several brain areas in the higher oxygen condition. These results suggest that while performing cognitive tasks, high concentrations of oxygen administration make oxygen administration sufficient, thus making neural network activate more, and the ability to perform cognitive tasks increase.

Cerebral Activation Area Following Oxygen Administration using a 3 Tesla Functional MR Imaging (고 자장 기능적 MR 영상을 이용한 뇌 운동 영역에서 산소 주입에 따른 활성화 영역에 관한 연구)

  • Goo, Eun-Hoe;Kweon, Dae-Cheol
    • Journal of the Ergonomics Society of Korea
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    • v.24 no.4
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    • pp.47-53
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    • 2005
  • This study aim to investigate the effects of supply of oxygen enhances cerebral activation through increased activation in the brain and using a 3 Tesla fMRI system. Five volunteers (right handed, average age of 21.3) were selected as subjects for this study. Oxygen supply equipment that provides 30% oxygen at a constant rate of 15L/min was given using face mask. A 3 Tesla fMRI system using the EPI BOLD technique, and three-pulse sequence technique get of the true axial planes scanned brain images. The author can get the perfusion images of the brain by oxygen inhalation with susceptibility contrast EPI sequence at the volunteers. Complex movement consisted of a finger task in which subjects flexed and extended all fingers repeatedly in union, without the fingers touching each other. Both task consisted of 96 phases including 6 activations and rests contents. Post-processing was done on MRDx software program by using cross-correlation method. The result shows that there was an improvement in performance and also increased activation in several areas in the oxygen method. These finding demonstrates that while performing cognitive tasks, oxygen administration was due to increase of cerebral activation.

Research on the Safety and Health Management and Asphyxiation Gas Concentration in Ginger Storage Tunnel (생강 저장굴의 질식 가스 농도 및 안전보건 관리 방향에 관한 연구)

  • Kim, Hyocher;Lee, Minji;Kim, Insoo;Lee, Kyeongsuk;Seo, Mintae;Cha, Jongjin;Kim, Kyungran
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.28 no.2
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    • pp.222-229
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    • 2018
  • Objectives: The aim of this study was to evaluate gas concentrations such as oxygen in ginger storage tunnels, which are the causes of asphyxiation in confined spaces and suggest directions for safety and health management at ginger farms. Methods: Five farms in the Seosan and Taean areas which use underground ginger storage tunnels were chosen and examined with a walk-through survey and direct reading device for oxygen, hydrogen sulfide, ammonia, and carbon monoxide. Results: The oxygen concentration in the storage tunnels with no ventilation was found to be under 18% in summer, which may cause health effects. The concentration in those with ventilation was about 19%. The difference in temperature by measurement day had little effect on the concentration of oxygen. Conclusions: Even though some of farms had used compulsory ventilation systems, none of the farms visited possessed any direct reading device for oxygen. Warning systems using a direct reading device can be more effective, helpful, and required compared to ventilation, considering the difficulty and expense of periodical maintenance of ventilation systems and the fact that a farmer can be placed in danger when unaware of the malfunction of the ventilation system. In addition, a warning system may make farmers more cognitive of agricultural safety and health actions while a ventilation system can cause them to become passive and ignorant of workplace hazards.

Release of Oxygen from a Nano-sized Water Droplet Observed using Molecular Dynamics

  • Lee, Chang-Han;Ambrosia, Matthew Stanley
    • Journal of Environmental Science International
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    • v.25 no.7
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    • pp.927-935
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    • 2016
  • Dissolved oxygen is necessary for many biological processes as well as many industrial practices. Dissolved oxygen released from water in dissolved air flotation (DAF) systems can be have many different applications. However, DAF systems are very costly to operate. To develop more efficient DAF systems, a deeper understanding of the process of oxygen being released from water is required. In this study, molecular dynamics (MD) simulations were used to simulate 100 oxygen molecules surrounded by 31002 water molecules at temperatures ranging from $0^{\circ}C$ to $100^{\circ}C$. Simulations were carried out for 10 ns, during which, in most cases, all the oxygen molecules were released from the water droplet. With MD simulations, visualization of the molecules escaping the water droplet was possible, which aided the understanding of the interactions between molecules at the nano-scale. The results showed that as the oxygen molecules moved near the edge of the water droplet that the oxygen molecules hesitated before escaping the water droplet or returned to the interior of the water droplet. This was because of the attractive forces between the water and oxygen molecules. Moreover, after most of the oxygen molecules were released from the droplet, some were found to return to the droplet's edge or even the interior of the droplet. It was also confirmed that oxygen molecules were released at a faster rate at higher temperatures.

Aspect of Blood Pressure after Oral Administration of Alcohol : Effect of Dissolved Oxygen on Blood Pressure (알코올 투여에 따른 혈압의 변화 양상 : 용존산소량에 따른 혈압 변화)

  • Song, Byung-Jeong;Lee, Byung-Yo;Chae, Jung-Woo;An, Jung-Hwa;Kwon, Kwang-Il
    • Korean Journal of Clinical Pharmacy
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    • v.22 no.3
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    • pp.228-233
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    • 2012
  • Purpose: The purpose of this study was to elucidate the effect of dissolved oxygen in alcohol to blood pressure of healthy persons. Methods: Subjects (n=30) were randomized in a double blind crossover study to receive 120 mL, 240 mL, 360 mL of alcohol (Korean spirit, 19.59 v/v%, dissolved oxygen is 8 ppm and 20 ppm). Blood alcohol concentration (BAC) and blood pressure were measured applying Lion SD-400 Alcolmeter$^{(R)}$ Breathalyser and Tensoval duo control. Pharmacokinetic parameters ($C_{max}$, $T_{max}$, $AUC_{last}$, $K_{el}$, $V_d$, Clearance) were calculated using Winnonlin$^{(R)}$ program. The difference of parameters and values were analysed by student t-test using Microsoft$^{(R)}$ Excel program. Results: The $AUC_{last}$ values of 8 ppm group and 20 ppm group in 240 ml administration were $6.15{\pm}2.60cg{\cdot}min/ml$, $5.33{\pm}1.84cg{\cdot}min/ml$ (p<0.05) and those in 360 mL were $11.93{\pm}5.70cg{\cdot}min/ml$, $10.33{\pm}4.60cg{\cdot}min/ml$ (p < 0.01), respectively. Thus, the $AUC_{last}$ was significantly decreased. On the other hands, there was a significant change in systolic blood pressure (SBP) after alcohol administration. All measured value after 360 mL of alcohol administration was significantly decreased (p < 0.01). Conclusions: The dissolved oxygen in alcoholic beverage has no effect on blood pressures but the alcohol administration has an effect on blood pressure. Thus, SBP can be used as a biomarker of alcohol administration and utilized in PK/PD modeling of alcohol.

Effect of Oxygen and Temperature Levels on the Seedling Characteristics of Korean and Anaerobic Germination-tolerant Rice under Flooding Conditions (담수 직파에서 산소 및 온도조건에 따른 혐기발아 내성 자원과 국내 직파 적응성 벼 품종의 입모특성 비교)

  • Jeong, Jong-Min;Kim, Jinhee;Mo, Youngjun;Ha, Su-Kyung;Kim, Woo-Jae;Kim, Bo-Kyeong;Jeung, Ji-Ung
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.64 no.4
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    • pp.287-298
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    • 2019
  • The aim of the present study was to compare the germination and seedling characteristics of rice varieties grown under various flooding conditions and different temperature and oxygen levels and to identify germplasm suitable for wet direct seeding. Three anaerobic germination tolerant (AGT) genotypes (PBR, WD3, KHO) and eleven Korean rice varieties (KVs) adapted for direct seeding were evaluated for seedling performance under different temperatures (15, 18, 21, and 24℃ ) and oxygen levels (Low, Normal, High). Compared with the KVs, the AGT genotypes (especially KHO and PBR) exhibited relatively high germination and survival rates and coleoptile and radical growth rates under low temperature and low oxygen conditions, thereby indicating their suitability for wet direct seeding. Among the KVs, 'Dongan,' 'Jungan,' and 'Cheongdam' rice exhibited the highest survival rates under low temperature and low oxygen conditions. Three-way ANOVA indicated that temperature had the greater effects on seedling characteristics (43.2-78.0%) than either oxygen level (15.4-37.5%) or genotype (2.0-29.8%) did. Therefore, in direct seeding cultivation, temperature was the most important environmental factor for seedling establishment.