• The Journal of Advanced Prosthodontics
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• v.8 no.5
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• pp.388-395
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• 2016

PURPOSE. The purpose of this study was to evaluate the resistance to deformation under static overloading by measuring yield and fracture strength, and to analyze the failure characteristics of implant assemblies made of different titanium grades and connections. MATERIALS AND METHODS. Six groups of implant assemblies were fabricated according to ISO 14801 (n=10). These consisted of the combinations of 3 platform connections (external, internal, and morse tapered) and 2 materials (titanium grade 2 and titanium grade 4). Yield strength and fracture strength were evaluated with a computer-controlled Universal Testing Machine, and failed implant assemblies were classified and analyzed by optical microscopy. The data were analyzed using the One-way analysis of variance (ANOVA) and Student's t-test with the level of significance at P=.05. RESULTS. The group $IT4_S$ had the significantly highest values and group IT2 the lowest, for both yield strength and fracture strength. Groups $IT4_N$ and ET4 had similar yield and fracture strengths despite having different connection designs. Group MT2 and group IT2 had significant differences in yield and fracture strength although they were made by the same material as titanium grade 2. The implant system of the similar fixture-abutment interfaces and the same materials showed the similar characteristics of deformation. CONCLUSION. A longer internal connection and titanium grade 4 of the implant system is advantageous for static overloading condition. However, it is not only the connection design that affects the stability. The strength of the titanium grade as material is also important since it affects the implant stability. When using the implant system made of titanium grade 2, a larger diameter fixture should be selected in order to provide enough strength to withstand overloading.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.17 no.6
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• pp.153-172
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• 2018

Overloading of Commercial vehicles have been an important area of transportation as one of the main causes of pavement damage, bridge collapse, severe traffic accident, etc. In this study, we analyzed the effects of overweight prevention by analyzing overweight driving patterns and using weight sensors. First, we analyzed relevant literatures of overweight and surveyed the commercial weight sensors. Then we chose the typical type of overweight vehicles based of overweight enforcement data analysis. MEMs inclinometer weight sensor were installed to 10 test vehicles and data was collected by weight sensors and gps in real time. As a result of gross vehicle weight and axle weight analysis, it was found weight sensor could decrease overweight rate. However, since the number of samples of test vehicles is insufficient to represent the whole commercial vehicle, further studies are deemed possible through the extension test.

• Journal of Yeungnam Medical Science
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• v.34 no.1
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• pp.19-28
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• 2017

The incidence of type 2 diabetes mellitus and insulin resistance is growing rapidly. Multiple organs including the liver, skeletal muscle and adipose tissue control insulin sensitivity coordinately, but the mechanism of skeletal muscle insulin resistance has not yet been fully elucidated. However, there is a growing body of evidence that lipotoxicity induced by mitochondrial dysfunction in skeletal muscle is an important mediator of insulin resistance. However, some recent findings suggest that skeletal mitochondrial dysfunction generated by genetic manipulation is not always correlated with insulin resistance in animal models. A high fat diet can provoke insulin resistance despite a coordinate increase in skeletal muscle mitochondria, which implies that mitochondrial dysfunction is not mandatory in insulin resistance. Furthermore, incomplete fatty acid oxidation by excessive nutrition supply compared to mitochondrial demand can induce insulin resistance without preceding impairment of mitochondrial function. Taken together we suggested that skeletal muscle mitochondrial overloading, not mitochondrial dysfunction, plays a pivotal role in insulin resistance.

• Structural Engineering and Mechanics
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• v.61 no.5
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• pp.593-603
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• 2017

A high-efficiency simplified modelling approach is proposed for investigating the nonlinear responses of reinforced concrete linings of shield tunnels. Material and geometric nonlinearities are considered in the analysis of the lining structures undergoing large deformation before ultimately losing the load-carrying capacity. A beam-spring element model is developed to capture the force-transfer mechanism between lining segments and radial joints. The developed model is validated by comparing analyzed results to experimental results of a single-ring lining structure under two loading conditions: the ground overloading and the lateral unloading respectively. The results show that the lining structure under the lateral unloading due to excavation on the both sides of the tunnel is more vulnerable compared to the case of ground overloading on the top of the tunnel. A parameter study is conducted and results indicate that the lateral pressure coefficient has the greatest influence on the behaviour of the lining structure.

• Corrosion Science and Technology
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• v.4 no.5
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• pp.211-216
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• 2005

Failure analysis of the latch ram ball and the C-ram ball with the trade name AFBMA Gr. 50 Colmonoy No. 6, has been performed to identify the root cause of the failure. The study required the extraction of the both failed and normal balls from the nuclear fuel exchanger. Microstructures of both balls were examined after polishing and etching. Breaking tests of both the ball revealed similarity in cleavage surfaces. Fracture surfaces of both failed ball and normal ball after breaking test were examined with SEM and EDX. Microstructure of the ball revealed an austenite phase with coarse Cr rich precipitate. Indented marks observed on the surface of the failed ball are believed to be produced by overloading. In the light of the afore mentioned observations and studies, the failure mechanism of the ball in nuclear fuel exchanger seem to be caused by impact or mechanical overloading on ball.

• Journal of the Korean Society of Safety
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• v.7 no.1
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• pp.20-29
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• 1992

Effects of strain hardening exponents on the retardation behavior of fatigue crack propagation are experimentally investigated. The retardation of fatigue crack propagation seems to be induced by the crack closure at crack tip. The phenomenon of crack closure becomes remarkable with the increment of strain hardening exponent and magnitude of percent peak load. The ratio of crack growth increment(a$\_$d//w$\_$d/) is influenced by a single overloading (a$\_$d/) and estimated plastic zone size (W$\_$d/=2r$\_$y/) is increased according with the increasing of strain ha.dening exponents. The number of retarded crack growth cycles were (N$\_$d/) decreased as the baseline stress intensity factor .ange( K$\_$b/) was increased. Within the limitation of these experimental results obtained under the single overload, an empirical relation between crack retardation ratio (Nd/N＊), strain hardening exponent (n) and percent peak load (％PL) has been proposed as; Nd/N＊＝ exp [PL $.$ PL$.$A(n)＋B(n) ] where, A(n)＝${\alpha}$n＋${\beta}$, B(n)＝${\gamma}$n＋$\delta$, PL＝％PL/100 and ${\alpha}$＝0.78, ${\beta}$＝0.54, ${\gamma}$＝0.58 and $\delta$＝-0.01, It is interesting to note that all these constants are identical for materials such as aluminum(A3203), steel(S4SC), steel(SS41) and stainless steel(SUS316) used in this experimental study.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2003.05a
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• pp.306-311
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• 2003

A growing fatigue crack is known to be retarded on application of an overload cycle. The retardation may be characterized by the total number of cycles involved during retardation and the retarded crack length. The overload ratio plays an important role to influence the retardation behavior. The objective of the present investigation is to study the effect of different overload ratio on the retardation behavior. For DENT(double edge notched tension) specimens and ESET(eccentrically-loaded single edge crack tension) specimens, fatigue crack growth tests are conducted under cyclic constant-amplitude loading including a single tensile overloading with different overload ratios. The proposed crack retardation model predicts crack growth retardation due to a single tensile overloading. The predictions are put into comparison with the experimental results to confirm the reliability of this model.

• Journal of Korean Society on Water Environment
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• v.22 no.3
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• pp.540-545
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• 2006

The anaerobic digester supernatant (ADS) with high $NH_4-N$ concentration often results in a $NH_4-N$ overloading to the mainstream process of municipal wastewater treatment plant (MWTP). The nitrogen removal from the ADS is therefore important in order to achieve a stable mainstream process performance as well as to prevent $NH_4-N$ overloading due to ADS. Recently because of several advantages compared to the full nitrification, many works have shown interests in controlling the build-up of $NO_2-N$ in nitritation processes. The application of nitritation could save the aeration power compared to the full nitrification processes. In addition, the denitrification of $NO_2-N$ could reduce organic carbon requirements compared to the $NO_3-N$ denitrification. The purpose of this research was to find out the characteristics of the ADS nitritation and $NO_2-N$ accumulating factors from the laboratory reactor study. As a result based on the long-term laboratory experiment, it can be concluded that the degree of nitritation was closely related with the availability of alkalinity, free ammonia (FA), solid retention time (SRT) and solid concentration in the nitritation reactor.

• The Korean Journal of Physiology and Pharmacology
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• v.23 no.1
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• pp.37-45
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• 2019

To study the effect of nicorandil pretreatment on ketone body metabolism and Acetyl-CoA acetyltransferase (ACAT1) activity in hypoxia/reoxygenation (H/R)-induced cardiomyocytes. In our study, we applied H9c2 cardiomyocytes cell line to evaluate the cardioprotective effects of nicorandil. We detected mitochondrial viability, cellular apoptosis, reactive oxygen species (ROS) production and calcium overloading in H9c2 cells that exposed to H/R-induced cytotoxicity. Then we evaluated whether nicorandil possibly regulated ketone body, mainly ${\beta}$-hydroxybutyrate (BHB) and acetoacetate (ACAC), metabolism by regulating ACAT1 and Succinyl-CoA:3-ketoacid coenzyme A transferase 1 (OXCT1) protein and gene expressions. Nicorandil protected H9c2 cardiomyocytes against H/R-induced cytotoxicity dose-dependently by mitochondria-mediated anti-apoptosis pathway. Nicorandil significantly decreased cellular apoptotic rate and enhanced the ratio of Bcl-2/Bax expressions. Further, nicorandil decreased the production of ROS and alleviated calcium overloading in H/R-induced H9c2 cells. In crucial, nicorandil upregulated ACAT1 and OXCT1 protein expressions and either of their gene expressions, contributing to increased production of cellular BHB and ACAC. Nicorandil alleviated cardiomyocytes H/R-induced cytotoxicity through upregulating ACAT1/OXCT1 activity and ketone body metabolism, which might be a potential mechanism for emerging study of nicorandil and other $K_{ATP}$ channel openers.

• Smart Structures and Systems
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• v.28 no.6
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• pp.761-777
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• 2021

This study presents a numerical investigation on the sensitivity of electromechanical (EM) impedance responses to inner damaged concrete of a prestressed anchorage zone. Firstly, the Ottosen yield criterion is selected to simulate the plasticity behavior of the concrete anchorage zone under the compressive loading. Secondly, several overloading cases are selected to analyze inner damage formations in the concrete of the anchorage zone. Using a finite element (FE) model of the anchorage zone, the relationship between applied forces and stresses is analyzed to illustrate inner plasticity regions in concrete induced by the overloading. Thirdly, EM impedance responses of surface-mounted PZT (lead-zirconate-titanate) sensors are numerically acquired before and after concrete damage occurrence in the anchorage zone. The variation of impedance responses is estimated using the RMSD (root-mean-square-deviation) damage metric to quantify the sensitivity of the signals to inner damaged concrete. Lastly, a novel PZT skin, which can measure impedance signatures in predetermined frequency ranges, is designed for the anchorage zone to sensitively monitor the EM impedance signals of the inner damaged concrete. The feasibility of the proposed method is numerically evaluated for a series of damage cases of the anchorage zone. The results reveal that the proposed impedance-based method is promising for monitoring inner damaged concrete in anchorage zones.