• Title/Summary/Keyword: overlapping expression

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Comprehensive Expression Analysis Suggests Functional Overlapping of Human FOX Transcription Factors in Cancer

  • Zhang, Ya-Li;Sun, Feng-Ting;Zhang, Ze;Chen, Xiao-Xu;Liu, Ai-Xiang;Pan, Jing-Jing;Peng, Fei;Zhou, Shuai;Sun, Li-Jun
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10475-10481
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    • 2015
  • Forkhead-box (FOX) transcription factors comprise a large gene family that contains more than 50 members in man. Extensive studies have revealed that they not only have functions in control of growth and development, but also play important roles in different diseases, especially in cancer. However, biological functions for most of the members in the FOX family remain unknown. In the present study, the expression of 39 FOX genes in 48 kinds of cancer was mined from the Gene Expression Atlas database of European Bioinformatics Institute. The analysis results showed that some FOX genes demonstrate overlapping expression in various cancers, which suggests particular biological functions. The pleiotropic features of the FOX genes make them excellent candidates in efforts aimed to give medical treatment for cancers at the genetic level. The results also indicated that different FOX genes may have the synergy or antagonistics effects in the same cancers. The study provides clues for further functional analysis of FOX genes, especially for the pleiotropic biological functions and crosstalk of FOX genes in human cancers.

A Study on the Structure and Characteristic of Overlapping of Storytelling about Experience Space - Focus on the Museum space - (체험 공간 스토리텔링의 중첩 구조 및 특성에 관한 연구 - 뮤지엄 공간을 대상으로 -)

  • Ahn, Hyunjeong
    • Korean Institute of Interior Design Journal
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    • v.22 no.4
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    • pp.41-51
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    • 2013
  • Lately in many cases, Spaces are designed by stimulating user's sensibility, emotion, psychological software over based on the user behavior and purpose of space. Because space is not only practical using and use purpose but also the place for expressing ourselves by experiences. But space is a physical thing. so we need to arrange a structure of abstract and formless source of design by sophisticated grammaticalization. Especially storytelling of that abstract thing have characteristics of relation, process among users and space. because storytelling is focused on the discourse of stories and relationship record of that discourses. So this is used by expression device for user's emotion things and subjects in numerous cases. And storytelling is the basic, important element for user's experience in a space. By the way, Overlapping is also basic element for being possible to make experiences by concrete thing. that is because, Overlapping is layering phenomenon of some objects. Overlapping is made distance, distance make depth, and this relations take us an experience. Finally storytelling, Overlapping and space of experience are relation of cause and effect. So in this thesis, researcher looks for the relation characteristics between storytelling and overlapping by experience. and makes the abstract source into concrete and sophisticated formular.

Relative Capacity of the Spectrum-Overlapped DS-CDMA System using the Lanczos Chip Waveform

  • Lee, Dong-Hun;Ryu, Heung-Gyoon
    • Journal of electromagnetic engineering and science
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    • v.2 no.1
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    • pp.1-4
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    • 2002
  • Performance improvement of the DS-CDMA system by the spectrum-overlap is important for better service quality or more system capacity. In this paper, an analysis thor capacity improvement is newly considered when the Lanczos chip waveform is used for the spectrum-overlapped DS-CDMA system. RC(relative capacity) is the ratio of the capacity of overlapping system to that of non-overlapping system, which is used for the expression of the capacity improvement. The optimal overlapping ratio is numerically found to make the maximum capacity improvement When the rectangular chip waveform is used far the overlapping system, maximum capacity improvement is increased by about 10% at the required BER=$10^{-3}$TEX> and the optimal overlapping ratio is 1.23. When the 95 % power bandwidth is considered for the Lanczos chip waveform, maximum capacity improvement is increased by 34.4% at overlapping ratio of 1.55 when the required BER is $10^{-3}$TEX>. The lower required BER far the better communication quality makes gradually smaller capacity improvement.

A Study on the Image-Virtualization in Fashion Illustration (패션 일러스트레이션에서의 이미지 가상화 연구)

  • Kim, Soon-Ja
    • Journal of the Korean Society of Clothing and Textiles
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    • v.32 no.3
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    • pp.505-516
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    • 2008
  • Image which appears in fashion illustration on the late twentieth century is not the representative image as an equivalence to the real fashion styles but the virtual image which bears no relation to any reality. The purpose of this study is review the concept of virtuality and analyze in which way virtual image is expressed in fashion illustrations on the background of Jean Baudrillard's simulacre theory. In post-modem paintings the expression methods of image-virtualization were image mixing through photo-image appropriation, image overlapping, and the icons inserted unreasonably, the focus-out effect through scrubbing and the over-painting on the photograph. Image-virtualization in fashion illustration was expressed through image mixing and expression of image uncertainty. Image mixing was made by photo-image appropriation, image overlapping, connection of heterogeneous images and using interface image, and uncertain image was expressed through the expression of visual ambiguity and virtual movement.

AN INTRODUCTION OF NEW SCHEDULING SOFTWARE "BEELINER" BASED ON THE BEELINE DIAGRAMMING METHOD (BDM)

  • Seon-Gyoo Kim
    • International conference on construction engineering and project management
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    • 2013.01a
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    • pp.391-396
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    • 2013
  • As the construction environment has been changing all the times, the techniques for managing the construction projects have been improved accordingly. The schedule management technique, one of the construction management tools, has been evolved as well in order to be adaptable to new construction environment. Most of newly proposed scheduling techniques have been based on the Critical Path Method (CPM) that was proposed in 1956. The CPM is classified into two categories, Arrow Diagramming Method (ADM) and Precedence Diagramming Method (PDM). ADM is so good in the visual format but it cannot express the overlapping relationships between two consecutive activities. On the other hand, PDM can express the overlapping relationships but it is unsatisfactory in the visual format. Recently, as the construction environment becomes more complex and the role of schedule management becomes more and more important, the overlapping expression becomes one of critical factors for scheduling as well. Most of construction project participants prefer more comfortable visual format, however, the scheduling software based on the PDM cannot satisfy their basic requirement. Beeliner, new scheduling software based on the Beeline Diagramming Method (BDM) that was proposed in 2010, was developed in 2012, it can express more flexible overlapping relationships and has superior visual format as well. This paper presents major features and applications of Beeliner, and makes construction professionals understand new scheduling concept and its applications.

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A Study on the Characteristics of Abstractive Form Expression in Contemporary Housing Architectures (현대 주거건축에 있어서 추상적 형태 표현 특성에 관한 연구)

  • Jang Hoon-Ick
    • Journal of the Korean housing association
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    • v.15 no.6
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    • pp.15-25
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    • 2004
  • This study examined how the characteristics of abstractive form among various contenporary housing architecture have been expressed. The conclusions were: First, abstractive characteristics and types related to from expression of contemporary housing architectures were minimal form and absolute form of geometrical abstraction, plastic form and atypical form of expressive abstraction and mechanical aesthetics of industrial abstraction. Second, the typological form expression characteristics in minimal expression related to geometrical abstraction were simplicity, purity, and the properties of matter, and the characteristics in absolute expression were overlapping, obliqueness and dispensability. On the other hand, plasticity and mobility of materials were distinctive in plastic form expression, and inclination, curve and asymmetry were distinctive in atypical expression. The distinctive nature of mechanical aesthetics related to industrial abstraction included transparency, simplicity and. the properties of matter Funhermore, the study aimed at the understanding of various from expressions showed up in contemporary housing architecture, revealing the aspects of abstractive form expression characteristics.

A Shared Inlining Method for Resolving the Overlapping Problem of Elements (엘리먼트의 중첩 문제를 해결한 Shared Inlining 저장 기법)

  • Hong, Eun-Il;Lee, Young-Ho
    • Journal of KIISE:Databases
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    • v.35 no.5
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    • pp.411-420
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    • 2008
  • The number of XML documents, which are widely used as a standard method for information expression and exchange in the web-based environment, increases rapidly along with the growing production of large XML documents. Many studies have been made to store and retrieve these XML documents on RDBMS, among which Shared Inlining storage method has a higher level of retrieval efficiency. The Shared Inlining method is the technique that analyzes the DTD information and stores the XML document in RDBMS by dividing for each node component. This study proposes the technique to resolve the overlapping problem that occurs in the element with several child nodes in the existing Shared Inlining method. The suggested method stores the XML document in the Shared Inlining structures appropriate to the DTD definition and enhances the accuracy of retrieval.

Dissipation Effects Induced by Substructures Comprised of Multiple oscillators (다수의 진동체로 구성된 부 구조물에 의한 감쇠 효과)

  • Choi, Sung-Hoon;Kim, Yang-Hann
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.12 no.6
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    • pp.445-452
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    • 2002
  • The goal of this paper Is to characterize the vibration damping induced in a main structure by a large number of sub-oscillators. A simple expression is obtained for the substructure impedance when the number of sub-oscillators approaches Infinity. It is found that the induced damping depends on the total mass of the sub-oscillators resonating in a frequency band of interests and nearly independent of their Individual loss factors. A modal overlapping condition. which corresponds to bandwidths that exceed the spacing of those natural frequencies, is required for the sub-oscillators to have such effects. An impulse response of the system is also considered. When the sub-oscillators lack damping and do not satisfy the modal overlapping condition, the vibratory energy is returned from the sub-oscillators to the main structure at later times. The result of this paper is consistent with that found with the fuzzy structure and SEA framework.

The Expressional Characteristics and Meanings of Indeterminacy in Fashion Illustrations (패션 일러스트레이션에 표현된 불확정성의 특성과 의미)

  • Kim, Soon Ja
    • Fashion & Textile Research Journal
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    • v.17 no.5
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    • pp.691-703
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    • 2015
  • Indeterminacy maintains that the simultaneous measurement of object location and speed is theoretically impossible. This study present indeterminacy as a theoretic tool to interpret a variety of expression characteristics that seem disorderly in recent fashion illustrations; in addition, it analyzes the characteristics and meaning of indeterminacy as expressed in fashion illustrations. This study reviews concepts and related theories on indeterminacy to examine characteristics of indeterminacy expressed in the arts and fashion; subsequently, indeterminacy characteristics found in fashion illustrations are analyzed. In expressing the fashion figure, indeterminacy finds expression in a distorted figure transformations that include a hybridized combination of heterogeneous forms that dismantle and reconstruct the human body. The hybridized body of combined machines, animals and plants indicates an indeterminate body endlessly transforming itself. Indeterminate space expression finds expression in space expression by projection with the overlapping and juxtaposition of irrelevant constituent elements as well as a space expression from the insertion of unexpected images. An unclarified inconclusive open space provides space with fluidity, causes space expansion and conveys inconclusive meaning. Indeterminate expressions found in fashion illustrations reveal the ambiguity and complexity of a post-modern society with polysemous aesthetic values and the expanded visual concepts of fashion illustrations.

Genomic and Proteomic Profiling of the Cadmium Cytotoxic Response in Human Lung Epithelial Cells

  • Choi, Kwang-Man;Youn, Hyung-Sun;Lee, Mi-Young
    • Molecular & Cellular Toxicology
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    • v.5 no.3
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    • pp.198-206
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    • 2009
  • Microarray and proteomic expression patterns in response to cadmium exposure were analyzed in human lung epithelial cells. Among 35,000 genes analyzed by cDNA microarray, 228 genes were up-regulated and 99 genes were down-regulated, based on a fold change cut-off value of ${\geq}2$. Combining two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization-time-of-flight-mass spectrometry (MALDI-ToF-MS), 25 of 629 protein spots showed fold changes in expression ${\geq}2$ (17 up-regulated, 8 down-regulated). After comparing the cDNA microarray and proteomic analyses, only transglutaminase 2, translation elongation factor 1 alpha 1, and glyceraldehyde-3-phosphate dehydrogenase showed overlapping signals in the cDNA microarray and proteomic analyses, whereas the remaining differentially expressed proteins showed large discrepancies with respect to mRNA expression.