• Title/Summary/Keyword: over consolidation

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Strength and Stiffness of Silty Sands with Different Overconsolidation Ratios and Water Contents (과압밀비와 함수비를 고려한 실트질 사질토 지반의 강도 및 변형 특성)

  • Kim Hyun-Ju;Lee Kyoung-Suk;Lee Jun-Hwan
    • Journal of the Korean Geotechnical Society
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    • v.21 no.9
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    • pp.53-64
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    • 2005
  • For geotechnical design in practice, soils are, in general, assumed to behave as a linear elastic or perfect plastic material. More realistic geotechnical design, however, should take into account various factors that affect soil behavior in the field, such as non-linearity of stress-strain response, stress history, and water content. In this study, a series of laboratory tests including triaxial and resonant column tests were peformed with sands of various silt contents, relative densities, stress states, OCR and water contents. This aims at investigating effects of various factors that affect strength and stiffness of sands. From the results in this study, it is found that the effect of OCR is significant for the intermediate stress-strain range from the initial to failure, while it may be ignored for the initial stiffness and peak strength. For the effect of water content, it is observed that the initial elastic modulus decreases with increasing water content at lower confining stress and relative density At higher confining stresses, the effect of water content Is found to become small.

Clofarabine in the Treatment of Elderly Patients with Acute Myeloid Leukemia

  • Aleem, Aamer;Anjum, Farhan;Algahtani, Farjah;Iqbal, Zafar;Alsaleh, Khalid;AlMomen, Abdulkareem
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.2
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    • pp.1089-1092
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    • 2013
  • Background: Elderly patients with acute myeloid leukemia (AML) have a poor outcome because of co-morbidities, poor tolerance to intensive chemotherapy and inherently more resistant disease. Clofarabine is a second generation nucleoside analogue which has shown promising activity in elderly patients with AML. This study was conducted to review the outcome of treatment with clofarabine in a group of such patients. Methods: The records of 5 elderly patients who were diagnosed to have AML and treated with clofarabine over a 12 month period were reviewed retrospectively. Results: There were 2 female and 3 male patients with a median age of 68 years (range 65-82). At the time of treatment, 2 patients had newly diagnosed AML not considered suitable for intensive therapy, while 3 patients had partial or no response to conventional chemotherapy. The overall response rate was 100%, all patients achieving a complete remission. Induction and consolidation were well tolerated. All patients developed neutropenia with a median duration of 20 days (range 17-42). One patient developed hand and foot syndrome and a generalized rash but recovered. There was no mortality and all patients remained in remission after a median follow-up of 5.2 months (Range 3-10). Conclusion: Clofarabine (alone or in combination) is active in elderly AML patients with an acceptable safety profile and should be considered a potential option in this group.

Analysis of Bicycle Accidents in Korea Based on Regional Characteristics (지역 특성을 고려한 국내 자전거 사고 분석)

  • KIM, Tae Yang;PARK, Byung Ho
    • Journal of Korean Society of Transportation
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    • v.35 no.5
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    • pp.447-457
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    • 2017
  • This study aims to analyze the accidents of green mode bicycle. In pursuing the above, this study gave special emphasis on modeling the bicycle accidents reflecting the regional characteristics. The main results are as follows. First, the null hypotheses that the number of accident and ratio of serious injury and fatality (FSI) were the same over regions were rejected. Second, as the common variables, the number of bicycle was judged to have positive (+) impact to the accidents and the bicycle using ratio was inferred to increase the ratio of FSI. Third, the elderly population ratio among 3 factors which gave impact to the accidents of Si_A (city-county consolidation) was concluded to have the greatest elasticity. The developed area ratio between 2 factors in Si_B (city which is not consolidated) was, however, estimated to have the higher elasticity. Fourth, the number of car registration among 5 accident factors of Gun (county) was analyzed to have the greatest elasticity. Finally, the commuting trip ratio among 7 accident factors of Gu (district) was judged to have the greatest elasticity. This study can be expected to give some implications to regional policy-making related to bicycle.

Peripheral Eosinophilia and Clinico-radiological Characteristics among Health Screening Program Recipients

  • Park, Tae Yun;Jung, Jae-Woo;Jang, Ju Young;Choi, Jae Chol;Shin, Jong Wook;Park, In Won;Choi, Byoung Whui;Kim, Jae Yeol
    • Tuberculosis and Respiratory Diseases
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    • v.81 no.2
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    • pp.156-162
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    • 2018
  • Background: Eosinophilia is well recognized in specific conditions. The objective of the present study was to determine clinico-radiologic characteristics of eosinophilia and changes in prevalence over 10 years in recipients of private health screening program at a tertiary hospital in Korea. Methods: Data of private health screening program recipients at the health promotion center of Chung-Ang University Hospital from 2004 to 2013 were collected. Health-related questionnaires and laboratory findings of private health screening program with possible relation with eosinophilia were reviewed. Results of enzyme-linked immunosorbent assay (ELISA) for parasite, chest computed tomography, and pulmonary function test were also reviewed. Results: The cumulative prevalence of eosinophilia was 4.0% (1,963 of 48,928). Prevalence of eosinophilia showed a decreased trend from 2004 to 2013. Most cases (96.6%) had mild degree of eosinophilia. Eosinophilic subjects were older and male-predominant. They showed lower levels of forced expiratory volume in 1 second ($FEV_1%$), forced vital capacity (FVC%), and $FEV_1/FVC$ than those without eosinophilia. Eosinophilic subjects showed higher positive rate for common parasite in ELISA than those without eosinophilia. On radiologic findings, consolidation and ground glass opacities were positively associated with the degree of eosinophilia. When eosinophil was classified based on severity, statistically significant correlation between the severity of eosinophil and radiologic abnormalities was found. Conclusion: Eosinophilia is uncommon in healthy population. It usually occurs at a mild degree. Eosinophilic patients have more radiologic abnormalities compared to those without eosinophilia. Such radiologic abnormalities are associated with the severity of eosinophilia.

An Analysis on the Processes of Observation Teaching and the Types of Observation in Elementary Life Science Classes (생명 현상에 관한 초등학교 관찰 수업 과정과 관찰 유형 분석)

  • Shin, Dong-Hoon;Shin, Jung-Ju;Kwon, Yong-Ju
    • Journal of Korean Elementary Science Education
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    • v.25 no.4
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    • pp.339-351
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    • 2006
  • The purpose of this study was to analyze the processes of observation teaching and the types of observation in elementary life science class. For the purposes of this study, 40 teachers majoring in elementary science education participated in surveys on the processes of observation teaching. In addition, after videotaping the observation classes conducted by three teachers, each teaching in the 3rd to 5th grade, and their one hundred and eight students, we analyzed the processes of observation teaching. As a result, the processes of observation leaching in elementary science class were categorized into 12 stages (motivation, stating the objective, recognizing objects to observe, free and subjective observation, introducing ways to observe, observing by the simple way, introducing additional ways, observing by the manipulative way, making a note of observation, looking over the contents of observation, finding regularities, consolidation). In the types of observation, teachers and students performed mostly simple observing by the visual way. Teachers introduced time-independent/non-compared/whole observing; students concentrated on time-independent/non-compared/particular observing as targets. Thus, students carried out observing in the types of observation that teachers had presented. Consequently, the analysis about the processes of observation teaching can establish an effective teaching program for observing in scientific activities by reconstructing its observing target and suitable topic. The analysis about the types of observation can be applied to set up strategies for improving observation skills.

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Analysis on Political Distrust of Governmental Agencies (정부기관의 정치 불신에 관한 실태분석)

  • Kim, Yong-Chul
    • Journal of Digital Convergence
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    • v.13 no.9
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    • pp.21-28
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    • 2015
  • This study shows what the political distrust of three nations was preserved among US, Japan, and South Korea in 2008. According to the World Value Survey research, the political distrust of three nations was reached over 70% when on the basis of national people's consciousness in 2008. Especially in the case of South Korea, the percentage of extreme distrust was the highest compared to the other countries. The reason why South Korea could not manage the nation people's political voice to the government and National Assembly. So consequently political complaining behavior channel should be erected more in the political mechanism. And Korean political parties could not manage the social development and national consolidation. Moreover, attacted the negative effects to society. Political distrust is the worst obstacle in democracy that it will be needed the national consensus to amend it.

A Study on the Efficiency of Import-Export Logistics through Advance Presentation of Vessel Manifest (해상적하목록 사전제출을 통한 수출입물류 효율화 방안에 관한 연구)

  • Kim, Yong-Jin;Seo, Dong-Gyun
    • Journal of Korea Port Economic Association
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    • v.27 no.2
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    • pp.275-296
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    • 2011
  • The purpose of this study was to examine ways of ensuring the efficiency and stability of import-export logistics in our country by introducing an advance presentation system of vessel manifest. This advance presentation system of vessel manifest has already been introduced in the United States, the EU and China whom our country has actively traded with, and the reinforcement of logistics security is a global trend. Under the circumstances, the introduction of the advance presentation system of vessel manifest is required to assist exporters to properly respond to changing trade practices as early as possible, and it's also necessary to exercise stricter control over an import criminal cargo. Our country should urgently introduce the advance presentation system of vessel manifest that is up to global standard, and the establishment of an internet based manifest consolidation and presentation system and the introduction of an export inspection system of port of loading are requested as well. If all the systems are introduced and work properly, that will make a great contribution to the efficiency of import-export logistics in our country.

Synthesis and Microstructure of Fe-Base Superalloy Powders with Y-Oxide Dispersion by High Energy Ball Milling (고에너지 볼 밀링을 이용한 Y-산화물 분산 Fe-기초내열합금 분말의 합성 및 미세조직 특성)

  • Yim, Da-Mi;Park, Jong Kwan;Oh, Sung-Tag
    • Korean Journal of Materials Research
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    • v.25 no.8
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    • pp.386-390
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    • 2015
  • Fe-base superalloy powders with $Y_2O_3$ dispersion were prepared by high energy ball milling, followed by spark plasma sintering for consolidation. High-purity elemental powders with different Fe powder sizes of 24 and 50 mm were used for the preparation of $Fe-20Cr-4.5Al-0.5Ti-O.5Y_2O_3$ powder mixtures (wt%). The milling process of the powders was carried out in a horizontal rotary ball mill using a stainless steel vial and balls. The milling times of 1 to 5 h by constant operation (350 rpm, ball-to-powder ratio of 30:1 in weight) or cycle operation (1300 rpm for 4 min and 900 rpm for 1 min, 15:1) were applied. Microstructural observation revealed that the crystalline size of Fe decreased with an increase in milling time by cyclic operation and was about 15 nm after 3 h, forming a FeCr alloy phase. The cyclic operation had an advantage over constant milling in that a smaller-agglomerated structure was obtained. The milled powders were sintered at $1100^{\circ}C$ for 30 min in vacuum. With an increase in milling time, the sintered specimen showed a more homogeneous microstructure. In addition, a homogenous distribution of Y-compound particles in the grain boundary was confirmed by EDX analysis.

A Study on the Mechanism of Soil Improvement Using Environment-friendly Organic Acid Material (친환경 유기산 재료를 활용한 지반개량 메커니즘에 관한 연구)

  • Lee, Jong-Hwi;Jung, Jae-Won;Han, Yun-Su;Chun, Byung-Sik
    • Journal of the Korean Geotechnical Society
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    • v.29 no.2
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    • pp.23-34
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    • 2013
  • An organic acid material, which can be manufactured by plants extraction, encourages microbe proliferation over time. Microbial activity, which is affected by organic acid, encourages accelerating consolidation with biochemical penetration; soil particles are compacted by microbes and pore water is dissipated quickly. Additionally, $CaCO_3$ for cementation was made by proliferating microbes. Accordingly, tests were conducted to investigate the unconfined compressive strength and permeability of soil samples aged with and without an organic acid. In the 96 days of aging, the strength was generally 1.5~2.5 times greater than those without an organic acid material and permeability was definitely decreased to 74.2~93.1%. SEM analysis showed the change of pore structure and the change of the total bacteria counts revealed the activity of microbes reflecting the engineering characteristics and this material would be an environment-friendly for soil improvement.

Correlation between the time elapsed after liposuction and the risk of fat embolism: An animal model

  • Lim, Kwang-Ryeol;Cho, Jeong-Min;Yoon, Chung-Min;Lee, Keun-Cheol;Lee, Sang-Yun;Ju, Mi-Ha
    • Archives of Plastic Surgery
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    • v.45 no.1
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    • pp.14-22
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    • 2018
  • Background Liposuction has become one of the most frequently performed procedures in the field of aesthetic surgery. Fat embolism syndrome after liposuction can easily be overlooked or underestimated; however, occasionally, fulminating fat embolism syndrome can develop and lead to a critical situation within 2-3 days after lipoplasty. Changes over time in the amount of circulating fat particles and the histology of major organs have not yet been studied. Methods This study was conducted using 18 male Sprague-Dawley rats aged 12 weeks and weighing 500-628 g (average, 562 g). Fifteen rats were used as the experimental group and 3 as the control group. Under general anesthesia, tumescent-technique liposuction was performed at the lateral flank areas and abdomen for 1 hour. Blood, lung, and brain tissue specimens were obtained at 1 hour, 1 day, and 2 days after the liposuction procedure. Results The average number of fat particles in the blood samples was 25,960/dL at 1 hour, 111,100/dL at 24 hours, and 21,780/dL at 48 hours. The differences between study groups were statistically significant. Both intravascular and extravascular fat particles with inflammation were seen in all 15 rats, as were inflammatory cell infiltration, hemorrhage, and consolidation with shrinkage of the lung alveoli. Conclusions These results imply that there is a strong possibility of fat embolism syndrome after liposuction in real clinical practice, and the first 24-48 hours after the operation were found to be the most important period for preventing pulmonary embolism and progression to fulminating fat embolism syndrome.