• Bulletin of the Korean Chemical Society
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• v.35 no.5
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• pp.1365-1374
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• 2014

Thirteen analogs of tridecapeptide ${\alpha}$-factor (WHWLQLKPGQPMY) of Saccharomyces cerevisiae with C- or N-terminal Trp extension and isosteric replacement by Aib at position 8 and 11, Trp at position 13, D-Ala at position 9, and Orn and Glu at position 6 were synthesized and assayed for their biological activity. Receptor binding assay was carried out using our newly developed spectrophotometric method with detector peptide 14. C- or N-terminal extended analogs, ${\alpha}$-factor-$[Trp]_n$ (n =1-5) 1-5 and $[N-Trp]_1$-${\alpha}$-factor 6, were all less active than native ${\alpha}$-factor and gradual decreases in both activity and receptor affinity were observed with greater Trp extension. Trp-substituted analog at position 13, $[Trp^{13}]{\alpha}$-factor 7, exhibited about 2-fold reductions in both activity and receptor affinity. Aib-substituted analogs, $[Aib^8]{\alpha}$-factor 8 and $[Aib^{11}]{\alpha}$-factor 9, showed 5- to 10-fold reduction in activity as well as 3-fold reduction in receptor affinity compared to native ${\alpha}$-factor. $[Orn^6]{\alpha}$-factor 10 demonstrated strong potency with a 7.0-fold increase in halo activity as well as 1.8-fold increase in receptor affinity compared to native ${\alpha}$-factor. For two double substituted analogs, [$Glu^6,{\small{D}}-Ala^9$]${\alpha}$-factor 12 showed the slightly decreased potency in halo activity compared to analog 10, whereas [$Orn^6,{\small{D}}-Ala^9$]${\alpha}$-factor 11 exhibited 15-fold higher halo activity as well as nearly 3-fold higher receptor affinity compared to native ${\alpha}$-factor.

• Journal of the Korean Society of Earth Science Education
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• v.5 no.3
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• pp.267-275
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• 2012

The purpose of this study is to find out the effect of the role-playing analogy activity-based class on the academic achievement in science and the science process skills of elementary school students. One experimental group and one control group of 4th grade students were selected to perform a prior investigation on the academic achievement in science and the science process skill. Then the experimental group attended science lessons that were based on the role-playing analogy activity and the control group attended the traditional science lessons based on the text book and teacher's guide. After conducting lessons, a post investigation was performed for each group and the results were analyzed to produce the following conclusions. First, the role-playing analogy activity class was more effective to improve students' academic achievements than the traditional science class. And the role-playing analogy activity class was more effective to learners in the high-level group, which made a scores above the average in prior investigation on the academic achievement, whereas it was little effective to those in the low-level group. Second, the role-playing analogy activity class was effective to enhance students' science process skills than the traditional science class. And the role-playing analogy activity class was more effective to the learners' in the high-level group than those in the low-level group.

• Journal of Korean Society of Rural Planning
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• v.19 no.2
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• pp.149-162
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• 2013

This study intended to suggest Voluntourism as a solution for alternative rural tourism for regional activation. Voluntourism is a form of alternative tourism on values of variety of tourism demand from pleasure to virtue. This study analyzed actual state of WWOOF(World-Wide Opportunities on Organic Farms) activities being operated in Korean rural village, one of representative of Voluntourism. Study aimed to explore the possibility of WWOOF activity as one of model of alternative rural tourism. We apply grounded theory method one of qualitative study methods for analysis of WWOOF Activities because WWOOF is still small activity in Korea. In result, we figure out the actual condition of WWOOF Korea activities as a vouluntourism through paradigm model of host and guest who had experience in WWOOF Korea. WWOOF activity is in its early stage so there many tasks. We suggested ideas for improving WWOOF activities to be one of new rural tourism business.

• The Korean Journal of Food And Nutrition
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• v.31 no.6
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• pp.844-857
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• 2018

This study evaluates antioxidant activity and quality characteristics of noodle adding domestic apiose (Apios americana Medikus) powder at the ratios of 0, 5, 10, 15, and 20%. The moisture content increased as more apiose was added while the pH decreased as more apiose was added. On the other hand, water absorption ratio and turbidity increased as more apiose was added. The L value decreased while the a value increased as more apiose was added. In texture, the hardness increased while cohesiveness decreased as more apiose was added. As a result, the overall preferences, the appearance, aroma, taste, and texture were the best when 15% apiose was added. In quantitative descriptive analysis (QDA), it turned out that brown color, bitter taste, delicate flavor, hardness, adhesiveness and chewiness increased as more apiose was added. However, crystallinity, spreadability, flour flavor, springiness decreased as more apiose was added. In principal component analysis (PCA), it was found out that when more than 15% apiose was added to the noodles. Antioxidant activity increased all for total phenolic, flavonoid contents and DPPH radical scavenging activity as more apiose was added. Collectively, it was noted that the preference, antioxidant activity and quality are the best when 15% apiose was added to noodles.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.3 no.1
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• pp.39-55
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• 1978

The following results have been driven out from a survey of the actual conditions of the public libraries service in Korea, made through questionnaire in reference with the actual service for youth that are presently done by the foreign countries' libraries, in order to prepare a perfect and objective base in establishing a service activities of the public libraries in this country: (1) It was found that the public libraries' loarning hours during the week days which accords with the schooling hours of the schools are shown to 50 %. On Saturdays during Summer season seven libraries and during Winter season twelve libraries would close their loaning before 17 : 00 hours, and on Holidays and Sundays fifteen libraries are not doing their loarning. (2) The followings are the present status of the service activities for the youth by the public libraries: a. It was found that they do introduction activity (50 %) of newly published books as a service for inducing reading interestings of the youth, and except this it was found that others are on beginning. b. The service activities by the data for the visual and auditory sense are almost negelected. and the rate of doing such activity is shown to 9.74%. c. It has been found that little information service activity is for inducing the youth to the libraries. d. As a cooperative activity with the school's, a passive service activity to have pursuaded to visit the public libraries by each class, are mostly being done (27.27%). Some research meeting for solving all the matters between the school libraries are not held mostly.

• Journal of the Korean Home Economics Association
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• v.41 no.12
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• pp.147-168
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• 2003

The researcher worked with 1001 middle and high school students so as to inquire into family-related variables affecting adolescents' school life maladjustment, relying on average, standard deviation and hierarchical regression. The following are the major findings. 1) The research shows that to look into school life maladjustment on the basis of analysis models including family environment variables and family relationship variables in addition to family background variables offers more explanatory power. 2) Of all the variables, parent relationship variables turned out to have the greatest influences on maladjustment to teacher relationship and teaming activity areas among the subordinate areas of school life maladjustment. 3) Of all the variables, family's physical variables have the greatest influence on maladjustment to regulation-keeping relationship and opposite sex relationship among the subordinate areas of school life maladjustment. 4) Of all the variables, sibling relationship variables have the greatest influence on maladjustment to friendship among the subordinate areas of school life maladjustment. 5) Parent relationship variables have the greatest influence on total school life maladjustment followed by family physical environment, structural environment, the number of family members, cultural environment and residential variables in the right order.

• Journal of the Korean Wood Science and Technology
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• v.50 no.2
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• pp.113-125
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• 2022

This study aimed to explore the biodiversity of chemical compounds found in the bark of Guibourtia tessmannii from Gabon, commonly called Kévazingo, and evaluate their anti-termite activity to determine their potential values as a source of development of anti-termite products that can be valued in the fields of fine chemicals and wood preservation. Extraction of G. tessmannii bark powders was carried out using the cold maceration method with trichloroethylene, acetone, ethanol, and water. Phytochemical screening made it possible to highlight groups of chemical families present in the extracts. Anti-termite activity was tested on the wild termites "Cubitermes sp" of the genus Isoptera. The yield of the extracts were 17.11% for the buttress and 13.42% for the height at 6 m. Phytochemical tests revealed that alkaloids, polyphenols, sterols, tannins, reducing compounds, flavonoids, saponins, and anthraquinones were present in the extracts. Results of anti-termite activity indicated that anti-termite activity varied with the different parts of the bark studied, extraction solvent, and concentration (50/50) and (25/75) of the extracts used. The extracts at 50/50 concentration showed a slightly better anti-termite activity compared to the 25/75 concentration. In addition, the buttress Kévazingo or buttress showed the strongest anti-termite activity for the aqueous extract with a survival rate of 0% after 2 days.

• The Korea Journal of Herbology
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• v.21 no.2
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• pp.121-127
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• 2006

Objectives : Nickel is a major metal used in the nickel-chromium alloys of most orthodontic appliances, partial denture and implants. This study was carried out for the examination of the cytotoxicity on nickel sulfide in cultured NIH3T3 fibroblasts, and poncirin effect on nickel-induced cytotoxicity. Methods : Cell viability for the MTT assay and cell adhesion activity for the XTT assay. Results : The $IC_{50}$ of nickel sulfide by the MTT assay was $93.7\;{\mu}M$. Poncirin was significantly increased the cell viability and cell adhesion activity. Conclusion : Nickel was highly toxic and poncirin has the inhibitory effects against nickel induced cytotoxicity.

• 대한공업교육학회지
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• v.39 no.1
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• pp.66-84
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• 2014

The purpose of this study is to develop STEAM hand-on activity task for middle school manufacturing & automation unit. This study was conducted following three stages. First of all, I carried out documents research and requirements analysis. And the goals for STEAM hand-on activity were set at this stage. Second, topics for STEAM hand-on activity were selected, and the organized for designing hand-on activity related STEAM in the development step. Finally, pilot and field test were conducted in order to amend and/or complement in improvement step. The theme and/or title of the hand-on activities were 'Making the print using wood', 'Making the close up photography & telephoto lens for smart phone'. The STEAM hand-on activities were designed for ten hours for each subject respectively. Each hand-on activity consists of problem situation, objectives statement, materials and tools, an evaluating criteria, related knowledge, portfolio and so on.

• Journal of the East Asian Society of Dietary Life
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• v.24 no.3
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• pp.301-314
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• 2014

This study was conducted in order to measure changes in the dining out consumption behaviors of the elderly living in Korea. Data on 2,316 and 3,170 elderly aged over 50 years were extracted from the 2001 and 2011 KNHANES(Korea National Health and Nutrition Examination Surveys), respectively. The data were analyzed by gender, age, region area, marital status, educational level, household income, economic activity and subjective health status. Frequency of dining out was higher in males between 50~64 years of age, living in metropolitan area, well-educated, high-income, engaged in economic activity and healthy. As a result, these basic data can be used for analyzing the changes in dining out consumption behaviors by sociodemographic characteristics of people aged over 50 years and the elderly in Korea. In the results on the consumption rate of food service in the two groups, 'female' and '65~74 years old' showed the largest increases from 10 years, and thus should be the group that the food service industry focuses on to develop new marketing strategies suitable for the environment.