• Title/Summary/Keyword: ostericum koreanum

Search Result 38, Processing Time 0.023 seconds

The study of Ostericum koreanum Radix & Aralia contientalis Radix in Bang-Yak-Hap-Pyun (방약합편중(方藥合編中) 강활(羌活) 및 독활(獨活)을 포함하는 처방(處方)에 대한 고찰(考察))

  • Lee, Joo-Ho;Yun, Il-Gi;Oh, Min-Suck
    • Journal of Haehwa Medicine
    • /
    • v.14 no.1
    • /
    • pp.167-177
    • /
    • 2005
  • In oriental medicine, Ostericum koreanum Radix & Aralia contientalis Radix are frequently used materials for strenthing lumbar and knees. Bang-Yak-Hap-Pyun(方藥合編) is widely used for clinical herbal prescription book. In Bang-Yak-Hap-Pyun, Ostericum koreanum Radix is used 1.2g~6g. and Aralia contientalis Radix is used 1.6g~4.8g. The most important fact is that the prescription used Ostericum koreanum Radix & Aralia contientalis Radix at the same time is 11. The number of prescription Ostericum koreanum Radix & Aralia contientalis Radix in Bang-Yak-Hap-Pyun is total 41. 5 in sang-tong(上統), 22 in jung-tong(中統), 14 in ha-tong(下統). The group of mostly used disease is about low back pain, knee pain, C.V.A., facail palsy, commom cold, numbness. The ratio of Ostericum koreanum Radix in Bang-Yak-Hap-Pyun is 3.03%~15.63%. And the ratio of Aralia contientalis Radix is 3.57%~12.00%. The mostly quoted medical literature what prescription included Ostericum koreanum Radix & Aralia contientalis Radix in Bang-Yak-Hap-Pyun is Dong-Yi-Bo-Gam. Man-Byeong-Hoi-Choon, and Hwa-Je-Gook-Bang.

  • PDF

Pharmacognostical Studies on the Kang Whal from Korea (한국강활의 생약학적 연구)

  • Park, Jong-Hee;Bae, Ji-Yung
    • Korean Journal of Pharmacognosy
    • /
    • v.38 no.4
    • /
    • pp.305-307
    • /
    • 2007
  • Chinese crude drug 'Kang Whal' has been used mainly as a headache in common cold, rheumatic arthralgia and aching of the back and shoulder. To clarify the botanical origin of Kang Whal from Korea, the anatomical characteristics of Ostericum koreanum Maxim. and Notopterygium incisium Ting ex H.T.Chang were studied. As a result, it was clarified that Kang Whal from Korea was the underground part of Ostericum koreanum.

Chemical Constituents of Ostericum koreanum Stem (강활(Ostericum koreanum) 줄기의 성분)

  • Ko, Ju Hyeong;Keum, Ji Hyun;Jung, Jae Won;Jhee, Hyun Kyu;Hong, Seung Pyo;Kim, Myong Jo;Chun, Wanjoo;Kwon, Yongsoo
    • Korean Journal of Pharmacognosy
    • /
    • v.51 no.3
    • /
    • pp.158-162
    • /
    • 2020
  • Three coumarins, one chromone, and a phytosterol were isolated from the stem of Ostericum koreanum. Basis on the spectral data, we determined to be the structures of isolated compounds as bergapten, xanthotoxin, auraptenol, hamaudol, and mixture of phytosterols. Auraptenol was isolated for the first time from this plant.

The Effects of Different Extracts of Ostericum koreanum on the Production of Inflammatory Mediators in LPS-stimulated RAW264.7 Cells (강활의 RAW264.7 세포에서 LPS에 의해 유도되는 염증물질 생성에 대한 효과)

  • Kim, Chang-Min;Park, Yong-Ki
    • The Korea Journal of Herbology
    • /
    • v.24 no.1
    • /
    • pp.169-178
    • /
    • 2009
  • Objectives : In this study, the effects of ethylacetate extract of Ostericum koreanum on inflammation in RAW264.7 cells were investigated. Methods : Dried roots of Ostericum koreanum was extracted with 80% methanol for 24 h, and then fractionated with n-butanol, n-hexan and ethylacetate. RAW264.7 cells, a mouse macrophage line were incubated with different concentrations of the extract for 30 min and then stimulated with LPS at indicated times. Cell toxicity was determined by MTT assay. The concentrations of nitric oxide (NO) and prostaglandin E2 ($PGE_2$) were measured by Griess assay and enzyme immunoassay (EIA), respectively. The expressions of inducible nitric oxide synthease (iNOS) and cyclooxyganase (COX) -2 mRNA and protein were determined by RT-PCR and Western blot. Results : The methanol extract of Ostericum koreanuman and its fractions were significantly inhibited the NO and PGE2 productions in LPS-stimulated RAW264.7 cells. Among the fractions of Ostericum koreanuman the ethylacetate fraction was more strongly inhibited NO and $PGE_2$ productions compared with other fractions. The ethylacetate fraction was also suppressed LPS-induced mRNA expressions of iNOS and its protein levels in RAW264.7 cells. Conclusions : This study suggests that the ethylacetate fraction of Ostericum koreanum may have an anti-inflammatory property through suppressing inflammatory mediator productions in activated macrophages, suggesting have a therapeutic potential for the treatment of various inflammatory diseases.

In Vitro Effects of Essential Oils from Ostericum koreanum against Antibiotic-Resistant Salmonella spp

  • Shin, Seung-Won
    • Archives of Pharmacal Research
    • /
    • v.28 no.7
    • /
    • pp.765-769
    • /
    • 2005
  • The essential oil fraction of Ostericum koreanum was analyzed by GC-MS. Inhibiting activities of this oil and its main components were tested by the broth dilution assay and disk diffusion test against one antibiotic-susceptible and two resistant strains of Salmonella enteritidis and S. typhimurium, respectively. The GC-MS analysis revealed thirty-four compounds; the main components were $\alpha$-pinene (41.12%), $\rho$-cresol (17.99%) and 4-methylacetophenone (7.90%). The essential oil of O. koreanum and its main components were significantly effective against the tested antibiotic-susceptible strains as well as against the resistant strains of the two Salmonella species, with MICs (minimum inhibitory concentrations) ranging from 2 mg/mL to 16 mg/mL. The anti-Salmonella effects of the oils were dose-dependent on $M\"{u}ller-Hinton$ agar plates in this experiment. Additionally, checkerboard titer test results demonstrated significant combined effects of streptomycin and O. koreanum oil or cresol, one of the main components of this oil, against the two streptomycin resistant strains of S. typhimurium, with FICIs ranging from 0.12 to 0.37.

Effect of Soil Texture and NPK Fertilizers Application Level on Growth and Yield of Ostericum koreanum (토성과 시비량에 따른 강활(羌活)의 생육과 수량변화)

  • Hur, Bong-Koo;Kim, Zhoo-Hyeon;Oh, O-Jin
    • Journal of agriculture & life science
    • /
    • v.44 no.2
    • /
    • pp.1-6
    • /
    • 2010
  • This study was carried out to investigate the effects of the various soil textures and NPK fertilizer application rates on growth and yield of Ostericum koreanum by pot experiment. Mean temperatures during cropping seasons of May, June, August and October were higher than those of normal year, but also the values were equal or lower for the other period. The growth and yield of Ostericum koreanum in the 1.5 fertilization rates became higher as the fertilizer rates increased by different soil textures. The content of soil organic matter and available phosphorus were high by application of high fertilization levels, while another contents did not show any significant differece. The yield of Ostericum koreanum was high in the loam soil by 278kg/10a. Those for clay soil was lower. Therefore, these results suggested that optimum soil texture for cultivation of this plant could be loam soil.

A Study on the Constituents of Bioactive Fractions of Ostericum koreanum Kitagawa (강활(羌活)의 생물활성분획(生物活性分劃)에 대한 성분연구(成分硏究))

  • Kwon, Yong-Soo;Woo, Eun-Ran;Kim, Chang-Min
    • Korean Journal of Pharmacognosy
    • /
    • v.22 no.3
    • /
    • pp.156-161
    • /
    • 1991
  • Four furocoumarins and two dihydrofuranocoumarin glycosides have been isolated from the benzene-soluble and butanol-soluble portions of the roots of Ostericum koreanum Kitagawa, respectively. Four furocoumarins have been determined as imperatorin, isoimperatorin, oxypeucedanin and oxypeucedanin hydrate, and two dihydrofuranocoumarin glycosides determined as marmesinin and $4'-O-{\beta}-D-glucopyranosyl-3'-hydroxymarmesin$ on the basis of spectral data and physico-chemical evidence.

  • PDF

Pharmacological Activities of Water Extracts of Umbelliferae Plants

  • Kim, Chang-Min;Heo, Moon-Young;Kim, Hyun-Pyo;Sin, Kwan-Seog;Pachaly, Peter
    • Archives of Pharmacal Research
    • /
    • v.14 no.1
    • /
    • pp.87-92
    • /
    • 1991
  • In order to evaluate the pharmacological activities of Chinese medicine, nine Umbelliferae plants were selected and their restoring activity against dexamethasone-induced disorders, liver protective activity, antimicrobial activity, anti-inflammatory activity and antimutagenic activity were tested and compared. Angelica dahurica. Angelica acutiloba and Ostericum koreanum showed various activities in these tests at the dose used in this study.

  • PDF