• Maxillofacial Plastic and Reconstructive Surgery
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• 제30권4호
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• pp.395-398
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• 2008

Bisphosphonate are a class of drugs with a chemical structure which inhibit bone resorption, actually used for metastatic bone disease, osteoporosis, Paget's disease and multiple myeloma. Significant complication associated with their use is reported recently : mandibular and maxillary osteomyelitis or osteonecrosis. So we here report our case about the patient who was diagnosed of prostate cancer in 2004 April and treated with bisphosphonate(Zoledronic acid-$Zometa^{(R)}$, Novartis Co.) intravenously every 3 to 4weeks at a dose of 4mg to prevent bone metastasis, and also, the patient who came to the hospital due to the bony exposure of mandible and pain in 2006 November and was diagnosed osteomyelitis of mandible as a result of biopsy, bone scan, PET CT examination.

• 대한치과보철학회지
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• 제59권3호
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• pp.314-318
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• 2021

미만성 경화성 골수염(diffuse sclerosing osteomyelitis, DSO) 환자에서 임플란트를 사용하여 손실된 치아의 회복에 대한 보고는 거의 없다. DSO 환자는 임플란트의 골유착에 불리한 골질을 지니고 있기 때문에 임플란트를 식립할 때, 외과적 외상, 감염 관리 및 연장된 치유 기간과 같은 추가적인 고려사항이 필수적이다. 본 증례는 DSO 환자에서 임플란트 골유착의 실패와 성공에 관한 보고이다.

• 미생물학회지
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• 제55권1호
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• pp.64-66
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• 2019

Cutibacterium acnes는 사람의 피부, 결막, 장관, 외이도 및 구강의 정상 세균 총의 하나이다. 이 세균 종은 여드름, 심내막염 감염, 유육종증, 뇌 농양, 치주염 및 골수염과 관련된 기회감 염성병원균으로 확인되었다. C. acnes KCOM 1315 (= ChDC KB81)는 사람 악골골수염 병소로부터 분리되었다. 여기에서 C. acnes KCOM 1315 균주 완전 유전체 염기서열을 해독하여 보고한다.

• Archives of Plastic Surgery
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• 제46권5호
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• pp.455-461
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• 2019

Background Various surgical management methods have been proposed for ischial sore reconstruction, yet it has the highest recurrence rate of all pressure ulcer types. A novel approach combining the advantages of a perforator-based fasciocutaneous flap and a muscle flap is expected to resolve the disadvantages of previously introduced surgical methods. Methods Fifteen patients with ischial pressure ulcers with chronic osteomyelitis or bursitis, who underwent reconstructive procedures with an inferior gluteal artery perforator (IGAP) fasciocutaneous flap and a split inferior gluteus maximus muscle flap from January 2011 to June 2016, were analyzed retrospectively. The split muscle flap was rotated to obliterate the deep ischial defect, managing the osteomyelitis or bursitis, and the IGAP fasciocutaneous flap was rotated or advanced to cover the superficial layer. The patients' age, sex, presence of bursitis or osteomyelitis, surgical details, complications, follow-up period, and ischial sore recurrence were reviewed. Results All ischial pressure ulcers were successfully reconstructed without any flap loss. The mean duration of follow-up was 12.9 months (range, 3-35 months). Of 15 patients, one had a recurrent ulcer 10 months postoperatively, which was repaired by re-advancing the previously elevated fasciocutaneous flap. Conclusions The dual-flap procedure with an IGAP fasciocutaneous flap and split inferior gluteus maximus muscle flap for ischial pressure ulcer reconstruction is a useful method that combines the useful characteristics of perforator and muscle flaps, providing thick dual padding with sufficient vascularization while minimizing donor morbidity and vascular pedicle injury.

• 한국임상수의학회지
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• 제37권6호
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• pp.342-344
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• 2020

Bacterial osteomyelitis-or bacterial infection of the bone-is common in reptiles. Unfortunately, its treatment is challenging despite advances in diagnostic and medical technologies. Herein, we present the case of a sexually mature female bearded dragon (Pogona vitticeps) with left forelimb elbow joint stiffness. We diagnosed the reptile with a eft elbow joint traumatic structural abnormality based on gross examination and evaluation of radiographs. Treatment with clindamycin and cephalexin for bacterial infection failed and the reptile died. Necropsy revealed the causative bacteria as Morganella morganii. Treatment of osteomyelitis is typically focused against Staphylococcus aureus as it the most common cause of traumatic bone infection. However, M. morganii, the causative bacterium in this case, has a natural resistance to clindamycin and cephalexin. Recently, these bacteria have begun to appear in clinical reports, more commonly as the causative organisms of bone infections. M. morganii should be considered as a potential cause of infection. Furthermore, antibiotic treatment in such cases should be based on bacterial culture and susceptibility tests.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권3호
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• pp.350-354
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• 2008

Mandibular chronic osteomyelitis with diffuse osteosclerosis is recognized as an intractable infectious disease. We emplyed decortication and intraarterial infusion of antibiotics in 6 cases. Decortication on the affected mandible was performed with retrocatherization to the superficial temporal artery of affected side under general anesthesia. Antibiotics, IPM/CS or FOMX was used through the artery for 4-11 days. In addition, we administered FOMX, PIPC intravenously for 8-17 days. CT and MRI were taken postoperatively. The postoperative follow-up period ranged from 1 year and 6 months to 2 years and 5 months. Postoperative MR showed that bone marrow signal was recovered to approximately normal in 4 cases. High signal area of bone marrow and osteosclerosis image remained in 2 cases, but showed improvement. The results were satisfactory without recurrence in all of 6 cases.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제36권6호
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• pp.285-291
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• 2014

Osteopathia striata with cranial sclerosis (OS-CS) is characterized by linear bone dysplasia at the long bone radiographically and sclerotic change at the cranium. The purpose of this case report is to study the symptoms and treatments of osteomyelitis in a patient with OS-CS. A 41-year-old patient had pus discharge from a fistula at the mental region and increase in radiolucencies with sequestra in panoramic radiograph images. Computed tomography (CT) as well as radiograph images for the whole skeleton were taken. The patient was diagnosed with OS-CS. Sequestrectomy and fistulectomy were performed. The patient recovered and no relapse occurred within six months after surgery. For diagnosis of OS-CS, CT and additional radiograph images for the whole skeleton are required. Because of the increased bone density, this patient is prone to relapse after sequestrectomy. Therefore, the surgeon must minimize trauma with the least incision and exfoliation, and preoperative antibiotics.

• 대한골관절종양학회지
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• 제11권2호
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• pp.183-187
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• 2005

유골 골종은 특징적인 방사선학적 소견과 임상양상으로 비교적 진단이 용이하나, 임상적 소견 및 방사선학적 검사상 아급성 경화성 골수염과 유사한 소견을 보여 진단이 지연되었던 경골근위부에 발생한 2개의 핵을 가진 유골 골종 1예를 경험하였기에 문헌고찰과 함께 보고 하고자 한다.

• Journal of Chest Surgery
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• 제36권3호
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• pp.215-218
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• 2003

65세 남자 환자가 우측 흉늑쇄골부위의 동통성 부종을 주소로 내원하였다. 환자는 과거력과 외상을 비롯한 특이 소견은 없었다. 입원 후 시행한 컴퓨터 단층촬영에서 우측경부의 농양과 우측 농흉소견이 나타났다. 개흉술로 우측 농흉제거술을 실시하였으며 우측 벽측 흉막과 우측 흉늑쇄골부위에 루가 발견되었다. 이어 경부절개를 통해 경부농양을 제거하였고 우측 흉늑쇄골부위에 골수염의 소견이 있어 우측쇄골일부, 제1번 늑연골, 흉골병 일부를 같이 제거하였다. 우측 흉늑쇄골부위의 골수염이 농흉으로 확대된 예는 드문 경우로서 저자들은 이를 치험 하였기에 보고하는 바이다.

• 미생물학회지
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• 제53권3호
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• pp.225-226
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• 2017

Streptococcus mitis는 그람 양성이면서, 통성 혐기성, 알파-용혈성 및 비운동성 구균이다. S. mitis는 인후, 비인두 및 구강내 정상세균총의 하나이고, 감염성 심내막염, 폐혈증 및 뇌수막염과 연관이 있다. KCOM 1350 (= ChDC B183) 균주가 사람 하악골 골수염 병소에서 분리되었다. S. mitis KCOM 1350 균주 유전체 염기서열을 해독하여 보고한다.