• 제목/요약/키워드: osseointegration.

검색결과 402건 처리시간 0.027초

In vivo comparison between the effects of chemically modified hydrophilic and anodically oxidized titanium surfaces on initial bone healing

  • Lee, Hyo-Jung;Yang, Il-Hyung;Kim, Seong-Kyun;Yeo, In-Sung;Kwon, Taek-Ka
    • Journal of Periodontal and Implant Science
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    • 제45권3호
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    • pp.94-100
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    • 2015
  • Purpose: The aim of this study was to investigate the combined effects of physical and chemical surface factors on in vivo bone responses by comparing chemically modified hydrophilic sandblasted, large-grit, acid-etched (modSLA) and anodically oxidized hydrophobic implant surfaces. Methods: Five modSLA implants and five anodized implants were inserted into the tibiae of five New Zealand white rabbits (one implant for each tibia). The characteristics of each surface were determined using field emission scanning electron microscopy, energy dispersive spectroscopy, and confocal laser scanning microscopy before the installation. The experimental animals were sacrificed after 1 week of healing and histologic slides were prepared from the implant-tibial bone blocks removed from the animals. Histomorphometric analyses were performed on the light microscopic images, and bone-to-implant contact (BIC) and bone area (BA) ratios were measured. Nonparametric comparison tests were applied to find any significant differences (P<0.05) between the modSLA and anodized surfaces. Results: The roughness of the anodized surface was $1.22{\pm}0.17{\mu}m$ in Sa, which was within the optimal range of $1.0-2.0{\mu}m$ for a bone response. The modSLA surface was significantly rougher at $2.53{\pm}0.07{\mu}m$ in Sa. However, the modSLA implant had significantly higher BIC than the anodized implant (P=0.02). Furthermore, BA ratios did not significantly differ between the two implants, although the anodized implant had a higher mean value of BA (P>0.05). Conclusions: Within the limitations of this study, the hydrophilicity of the modSLA surface may have a stronger effect on in vivo bone healing than optimal surface roughness and surface chemistry of the anodized surface.

골밀도 평가방법과 임플란트 안정성 변화의 관찰 (Observation of the change of the dental implant stability and bone density evaluation methods)

  • 고석민;박성재;김인수;송승일;이인경
    • Journal of Periodontal and Implant Science
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    • 제39권2호
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    • pp.185-192
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    • 2009
  • Purpose: The aim of this study was to examine the correlation of the subjective and the objective evaluation of edentulous ridge bone quality, and to evaluate the change of the dental implant stability in each bone density group for early healing period after implant installation. Methods: Sixty-seven implants(Osstem implant$^{(R)}$, Seoul, Korea) were included in this study. We evaluated the bone density by 2 methods. The one was the subjective method which was determined by practitioner s tactile sense, the other was the objective bone type was based on Hounsfield units. The implant stability in each bone type group was assessed by resonance frequency analyzer(Osstell mentor$^{(R)}$). Data were analyzed for the change of the implant stability, and they were compared to verify the difference of groups at the time of installation, 2, 6, 10, 14 weeks postoperatively. Spearman's correlation was used to demonstrate the correlation between the subjective and the objective evaluation of the bone density, and analysis of variance(ANOVA) was used to analyze the differences of implant stability at each time point. Results: There was no close relation between the subjective and the objective evaluation of the bone density(r=0.57). In the subjective groups, there was statistically significant difference between the type 1 and 3 at 10 weeks and between the type 2 and 3 at 14 weeks. In the objective groups, there was no statistically significant difference between the D 1, 2, 3, 4, and 5 group with regard to RFA from baseline to 14 weeks(P>0.1). Conclusions: The implant stability increased over time during the study, and it was improved with bone density proportionally after 2weeks postoperatively. It is recommended that the decision of bone density is base on Hounsfield unit for implant loading time.

상온 대기압 플라즈마의 치의학적 응용 (Applications of Non-Thermal Atmospheric Pressure Plasma in Dentistry)

  • 엄수혁;권재성;이정환;이은정;김경남
    • 대한치과의사협회지
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    • 제52권12호
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    • pp.783-794
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    • 2014
  • Since the introduction of non-thermal atmospheric pressure plasma in the field of the dentistry, numerous applications have been investigated. Especially with its advantages over existing vacuum plasma in terms of portability, low cost, and non-thermal damage, it can be directly applied in the oral cavity, giving number of potentials for dental application. First, possible application of non-thermal atmospheric pressure plasma in the field of dentistry is relation to dental caries and periodontal diseases. Teeth and alveolar bones are one of the strongest bony structures in our body, but it cannot be regenerated when they are damaged by dental caries or periodontal disease. Hence many studies to prevent such diseases have been carried out, though no perfect solution has been found yet. With recent studies of modifying surfaces through non-thermal atmospheric pressure application that can prevent attachment of bacteria, or studies on bactericidal effects of non-thermal atmospheric pressure plasma can be applied here to prevent oral pathogen and 'biofilm' attachment to the surface of teeth or directly eliminate the dental caries/periodontal disease causing germs. Secondly, non-thermal atmospheric pressure application will be useful on the surface of dental implant. It is well known that the success of dental implant surgery depends on the process known as 'osseointegration' that result from osteoblast attachment, proliferation and differentiation. As the application of non-thermal atmospheric pressure plasma on the surface of dental implant just before its introduction by the chair-side of dental surgery. Despite its long history, the generation of non-thermal atmospheric pressure plasma has been greatly increased with its application in dentistry.

경사하중에 따른 시멘트 유지형 임플란트 지지골의 유한요소법 응력 분포 (Finite Element Analysis of Stress Distribution on Supporting Bone of Cement Retained Implant by Oblique Loading)

  • 이명곤
    • 한국콘텐츠학회논문지
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    • 제14권9호
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    • pp.343-349
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    • 2014
  • 본 연구는 치과 임상에서 사용하고 있는 시멘트 유지형 치과용 임플란트의 지지골 응력 분포 안정성을 확인하고자 시행하였다. 모델링과 유한요소 응력 분석은 유한요소 해석 프로그램인 Solidworks를 사용하였고, 시멘트 유지형 임플란트 시스템인 지대주와 고정체를 연결하는 지대주 나사를 20 Ncm 나사조임력에 의한 결합조건을 적용시킨 단관 모델을 제작하고, 설측에서 협측으로의 $45^{\circ}$ 경사로 100 N 크기 외부하중을 가하여 지지골 응력 분포 해석을 실시하였다. 경사하중에 따른 임플란트 고정체의 지지골 응력 크기와 분포를 파악하기 위한 유한요소법 분석을 통해 다음 결과를 얻었다. 고정체 직경, 길이의 조건에 관계없이 임플란트 고정체 상부와 골 접촉부인 치밀골에 응력이 집중되는 양상으로 나타났고, 고정체 길이 증가로 인한 응력 감소 폭보다 직경 증가로 인한 감소폭이 큰 것으로 나타났다 따라서 본 연구 결과는 지지골 형태 조건에 대하여 가능한 큰 직경의 고정체 사용이 효과적이라고 판단된다.

골유착성 보철물에 관한 삼차원 유한요소분석적 연구 (A STUDY ON THE OSSEOINTEGRATED PROSTESIS USING THREE DIMENSIONAL FINITE ELEMENT METHOD)

  • 김동원;김영수
    • 대한치과보철학회지
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    • 제29권1호
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    • pp.167-213
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    • 1991
  • The successful replacement of missing teeth has been one driving aim behind the emergence of implant dentistry as both a technology and clinical vocation for over four decades. To date, a multitude of dental implant devices had been designed and utilized in the patient population. Most of these devices have been designed without support of the engineering criteria. The long-term success of any dental implant is dependent upon the optimization of stresses which occurs during oral function and parafunction. Although many studies have examined the biologic interactions between dental implants and living tissue, few studies have been reported on the biomechanical aspects of dental implants. The purpose of this study was to analyze the stress distribution of osseointegrated prosthesis on certain conditions, such as amount of load, location of load, length of fixtures, number of fixtures used, arch shape, bone quality, etc. Three dimentional finite element analysis was used for this study. FEM models were created using commercial software(Super SAP. for IBM 16 bit AT computer. All elements were 8-node brick, isoparametric. Mandible and prosthesis was modeled with 780 elements and 1074 nodes. The results were as follows : 1. In case of cantilever extension, there was a compressive stress at the base of the first implant and a tensile stress at the base of the second implant. 2. The stresses were linearly proportional to the amount of load. 3. The stresses were linearly proportional to the length of cantilever. 4. There was a stress concentration at the neck of the implant and bone under horizontal loads.

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SURFACE ANALYSES OF TITANIUM SUBSTRATE MODIFIED BY ANODIZATION AND NANOSCALE Ca-P DEPOSITION

  • Lee, Joung-Min;Kim, Chang-Whe;Lim, Young-Jun;Kim, Myung-Joo
    • 대한치과보철학회지
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    • 제45권6호
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    • pp.795-804
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    • 2007
  • Statement of problem. Nano-scale calcium-phosphate coating on the anodizing titanium surface using ion beam-assisted deposition (IBAD) has been recently introduced to improve the early osseointegration. However, not much is known about their surface characteristics that have influence on tissue-implant interaction. Purpose. This study was aimed to investigate microtopography, surface roughness, surface composition, and wettability of the titanium surface modified by the anodic oxidation and calcium phosphate coating using IBAD. Material and methods. Commercially pure titanium disks were used as substrates. The experiment was composed of four groups. Group MA surfaces represented machined surface. Group AN was anodized surface. Group CaP/AN was anodic oxidized and calcium phosphate coated surfaces. Group SLA surfaces were sandblasted and acid etched surfaces. The prepared titanium discs were examined as follows. The surface morphology of the discs was examined using SEM. The surface roughness was measured by a confocal laser scanning microscope. Phase components were analyzed using thin-film x-ray diffraction. Wettability analyses were performed by contact angle measurement with distilled water, formamide, bromonaphtalene and surface free energy calculation. Results. (1) The four groups showed specific microtopography respectively. Anodized and calcium phosphate coated specimens showed multiple micropores and tiny homogeneously distributed crystalline particles. (2) The order of surface roughness values were, from the lowest to the highest, machined group, anodized group, anodized and calcium phosphate deposited group, and sandblasted and acid etched group. (3) Anodized and calcium phosphate deposited group was found to have titanium and titanium anatase oxides and exhibited calcium phosphorous crystalline structures. (4) Surface wettability was increased in the order of calcium phosphate deposited group, machined group, anodized group, sandblasted and acid etched group. Conclusion. After ion beam-assisted deposition on anodized titanium, the microporous structure remained on the surface and many small calcium phosphorous crystals were formed on the porous surface. Nanoscale calcium phosphorous deposition induced roughness on the microporous surface but hydrophobicity was increased.

COMPARISON BETWEEN $TIUNITE^{TM}$ AND ANOTHER OXIDIZED IMPLANT USING THE RABBIT TIBIA MODEL

  • Yeo, In-Sung;Lee, Jai-Bong;Han, Jung-Suk;Kim, Sung-Hun;Yang, Jae-Ho
    • 대한치과보철학회지
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    • 제45권3호
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    • pp.339-344
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    • 2007
  • Statement of problem. Various anodic oxidation techniques can be applied to dental implant surfaces. But the condition for optimal anodized surfaces has not been described yet. Purpose. The purpose of this investigation was to compare an implant that was oxidized by another method with $TiUnite^{TM}$ through resonance frequency analysis and histomorphometry. Material and methods. Turned (control), $TiUnite^{TM}$ and another oxidized fixtures, which used $Ca^{2+}$ solution for anodic oxidation, were placed in the tibiae of 5 New Zealand White rabbits. The bone responses were evaluated and compared by consecutive resonance frequency analysis once a week for 6 weeks and histomorphometry after a healing period of 6 weeks. Results. At the first week, both oxidized implants showed significantly higher implant stability quotient (ISQ) values than the control. No significant differences in resonance frequency analysis were found between the two oxidized groups for 6 weeks. The means and standard deviations of bone-to-implant contact (BIC) ratios were $71.0{\pm}4.2$ for $TiUnite^{TM}$, $67.5{\pm}10.3$ for the $Ca^{2+}$-based oxidation fixture, $22.8{\pm}6.5$ for the control. Both oxidized implants were significantly superior in osseointegration to the turned one. There was, however, no statistically significant difference between the two oxidized implants. Conclusion. $TiUnite^{TM}$ and the $Ca^{2+}$-based oxidation fixture showed superior early bone response than the control with respect to resonance frequency analysis and histomorphometry. No significant differences between the oxidized groups, however, were found in this investigation using the rabbit tibia model.

A comparison of the implant stability among various implant systems: clinical study

  • Kim, Jae-Min;Kim, Sun-Jong;Han, In-Ho;Shin, Sang-Wan;Ryu, Jae-Jun
    • The Journal of Advanced Prosthodontics
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    • 제1권1호
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    • pp.31-36
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    • 2009
  • PURPOSE. To determine the change in stability of single-stage, three different design of implant systems in humans utilizing resonance frequency analysis for early healing period(24 weeks), without loading. MATERIAL AND METHODS. Twenty-five patients were included into this study. A total of 45 implants, three different design of implant systems(group A,C,R) were placed in the posterior maxilla or mandible. The specific transducer for each implant system was used. ISQ(implant stability quotient) reading were obtained for each implant at the time of surgery, 3, 6, 8, 10, 12, 24 weeks postoperatively. Data were analyzed for different implant type, bone type, healing time, anatomical locations. RESULTS. For each implant system, a two-factor mixed-model ANOVA demonstrated that a significant effect on ISQ values(group A=0.0022, C=0.017, R=0.0018). For each implant system, in a two-factor mixed model ANOVA, and two-sample t-test, the main effect of jaw position(P > .005) on ISQ values were not significant. CONCLUSIONS. All the implant groups A, C and R, the change patterns of ISQ over time differed by bone type. Implant stability increased greatly between week 0 and week six and showed slow increase between week six and six months(plateau effect).

Cell response to a newly developed Ti-10Ta-10Nb alloy and its sputtered nanoscale coating

  • Kim, Young-Min;Vang, Mong-Sook;Yang, Hong-So;Park, Sang-Won;Lim, Hyun-Pil
    • The Journal of Advanced Prosthodontics
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    • 제1권1호
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    • pp.56-61
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    • 2009
  • STATEMENT OF PROBLEM. The success of titanium implants is due to osseointegration or the direct contact of the implant surface and bone without a fibrous connective tissue interface. PURPOSE. The purpose of this study was to evaluate the osteoblast precursor response to titanium-10 tantalum-10 niobium(Ti-Ta-Nb) alloy and its sputtered coating. MATERIAL AND METHODS. Ti-Ta-Nb coatings were sputtered onto the Ti-Ta-Nb disks. Ti6-Al-4V alloy disks were used as controls. An osteoblast precursor cell line, were used to evaluate the cell responses to the 3 groups. Cell attachment was measured using coulter counter and the cell morphology during attachment period was observed using fluorescent microscopy. Cell culture was performed at 4, 8, 12 and 16 days. RESULTS. The sputtered Ti-Ta-Nb coatings consisted of dense nanoscale grains in the range of 30 to 100 nm with alpha-Ti crystal structure. The Ti-Ta-Nb disks and its sputtered nanoscale coatings exhibited greater hydrophilicity and rougher surfaces compared to the Ti-6Al-4V disks. The sputtered nanoscale Ti-Ta-Nb coatings exhibited significantly greater cell attachment compared to Ti-6Al-4V and Ti-Ta-Nb disks. Nanoscale Ti-Ta-Nb coatings exhibited significantly greater ALP specific activity and total protein production compared to the other 2 groups CONCLUSIONS. It was concluded that nanoscale Ti-Ta-Nb coatings enhance cell adhesion. In addition, Ti-Ta-Nb alloy and its nanoscale coatings enhanced osteoblast differentiation, but did not support osteoblast precursor proliferation compared to Ti-6Al-4V. These results indicate that the new developed Ti-Ta-Nb alloy and its nanoscale Ti-Ta-Nb coatings may be useful as an implant material.

3차원 디지털 영상과 CAD/CAM 시스템을 활용한 전악 임플란트 수복 증례 (Full mouth rehabilitation with dental implant utilizing 3D digital image and CAD/CAM system: case report)

  • 강세하;정승미;신재옥;방정환;김대환;최병호
    • 구강회복응용과학지
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    • 제31권2호
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    • pp.158-168
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    • 2015
  • 본 증례는 상 하악 완전 무치악 환자에서 진단, 식립 그리고 보철물 제작에 디지털 방식을 활용하는 방법에 대해 제시하였다. 상악은 구개 부위, 하악은 기존 의치에 방사선 불투과성 마커를 부착한 후 구강스캔 및 CBCT 촬영을 시행하였다. 구강스캔 이미지와 CBCT 이미지를 중첩시켜 진단 및 수술가이드와 임시보철물을 제작하였다. 골유착 후에는 스캔바디를 이용한 구강스캔을 통해 최종보철물을 제작하였다. 임플란트를 이용한 전악수복에서 디지털 방식을 다양하게 활용하였으며 정확성과 환자의 불편감 최소화라는 목적에 만족할만한 결과를 얻었기에 이 증례를 보고하고자 한다.