• Investigative Magnetic Resonance Imaging
• /
• v.22 no.3
• /
• pp.158-167
• /
• 2018

Purpose: To investigate the surgical, perfusion, and molecular characteristics of glioblastomas which influence long-term survival after treatment, and to explore the association between MR perfusion parameters and the presence of MGMT methylation and 1p/19q deletions. Materials and Methods: This retrospective study was approved by our institutional review board. A total 43 patients were included, all with pathologic diagnosis of glioblastoma with known MGMT methylation and 1p/19q deletion statuses. We divided these patients into long-term (${\geq}60\;months$, n = 7) and short-term (< 60 months, n = 36) survivors, then compared surgical extent, molecular status, and rCBV parameters between the two groups using Fisher's exact test or Mann-Whitney test. The rCBV parameters were analyzed according to the presence of MGMT methylation and 1p/19q deletions. We investigated the relationship between the mean rCBV and overall survival using linear correlation. Multivariable linear regression was performed in order to find the variables related to overall survival. Results: Long-term survivors (100% [7 of 7]) demonstrated a greater percentage of gross total or near total resection than short-term survivors (54.5% [18 of 33]). A higher prevalence of 1p/19q deletions was also noted among the long-term survivors (42.9% [3 of 7]) than the short-term survivors (0.0% [0 of 36]). The rCBV parameters did not differ between the long-term and short-term survivors. The rCBV values were marginally lower in patients with MGMT methylation and 1p/19q deletions. Despite no correlation found between overall survival and rCBV in the whole group, the short-term survivor group showed negative correlation ($R^2=0.181$, P = 0.025). Multivariable linear regression revealed that surgical extent and 1p/19q deletions, but not rCBV values, were associated with prolonged overall survival. Conclusion: While preoperative rCBV and 1p/19q deletion status are related to each other, only surgical extent and the presence of 1p/19q deletion in GBM patients may predict long-term survival.

• Journal of Korea Water Resources Association
• /
• v.46 no.9
• /
• pp.933-946
• /
• 2013

The quantitative analysis of evapotranspiration (ET) is a key component in hydrological studies and the establishment of water resources planning. Generally, the quantitative analysis of ET is performed by the estimation method of potential or reference ET based on meteorological factors such as air temperature, wind speed, etc. Hargreaves equation is one of empirical methods for reference ET using air temperature data. In this study, in order to estimate more exact reference ET considering climatological characteristics in Korea, parameter regionalization of Hargreaves equation is carried out. Firstly, modified Hargreaves equation is presented after the analysis of the relationship between solar radiation and temperature. Secondly, parameter ($K_{ET}$) optimization of Hargreaves equation is performed using Penman-Monteith method and modified equation at 71 weather stations. Lastly, the equation for calculating $K_{ET}$ using temperature data is proposed and verified. As a result, reference ET from original Hargreaves equation is overestimated or underestimated compared with Penman-Monteith method. But modified equation in this study is more accurate in the climatic conditions of Korea. In addition, the applicability of the equation between $K_{ET}$ and temperature is confirmed.

• Land and Housing Review
• /
• v.7 no.4
• /
• pp.207-215
• /
• 2016

The purpose of this paper is to explore ways in the construction of Apartment-type factories in the public sector. Recently the markets of Apartment-type factories are driven by the private sector as high quality, high price and supply of in the form of office, these construction trends are different from the original aim of introduce policy of Apartment-type factories which supply production spaces in the city to small capital enterprises. We analyzed the architectural characteristics of Apartment-type factories in Korea, the prospect of their future construction trends and the survey results targeted to small enterprises. In the results of this survey, we grope for the direction for construct Apartment-type factories in the public sector. The Apartment-type factories constructed by the public sector are appropriate supply for manufacturing plants and sale rather than lease form to complement the private market. To optimize economically and functionally for manufacturing activities, the design space in the internal and external spaces is required in order to supply more affordable. Route design, especially considering parking, unloading and warehousing of merchandise, and logistics should be differentiated from the Apartment-type Factories constructed by private sector.

• Journal of Korea Water Resources Association
• /
• v.51 no.11
• /
• pp.1031-1041
• /
• 2018

ANFIS-based methodology for improving GloSea5 ensemble weather forecast is developed and evaluated in this study. The proposed method consists of two steps: pre & post processing. For ensemble prediction of GloSea5, weights are assigned to the ensemble members based on Optimal Weighting Method (OWM) in the pre-processing. Then, the bias of the results of pre-processed is corrected based on Model Output Statistics (MOS) method in the post-processing. The watershed of the Chungju multi-purpose dam in South Korea is selected as a study area. The results of evaluation indicated that the pre-processing step (CASE1), the post-processing step (CASE2), pre & post processing step (CASE3) results were significantly improved than the original GloSea5 bias correction (BC_GS5). Correction performance is better the order of CASE3, CASE1, CASE2. Also, the accuracy of pre-processing was improved during the season with high variability of precipitation. The post-processing step reduced the error that could not be smoothed by pre-processing step. It could be concluded that this methodology improved the ability of GloSea5 ensemble weather forecast by using ANFIS, especially, for the summer season with high variability of precipitation when applied both pre- and post-processing steps.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2011.05a
• /
• pp.20-20
• /
• 2011

The purpose of this research aims to evaluate the emergence of new business mode in the Chinese water market since the mid-2000s - Transfer-Operate-Transfer(TOT) Projects. The study pays special attention to the case of the Hefei Wangxiaoying Wastewater Treatment TOT Project, which was awarded to the consortium of Berlin Water International and its Chinese partner in late 2004. The consortium secured an exclusive operating right for 23 years on the basis of a TOT scheme and would take responsibility of all the profits and losses in the operation of the plant. The total investment for the transfer amounted to RMB 491 million(US$70 million). The price was more than 288% of the original value, RMB 170 million (US$24 million). The project can be regarded as a successful case because of the following three causes. First, the Hefei government followed a series of standardized procedures in the international bidding, which ignited best-performed international players' competition for the project. Second, the project will bring in cutting-edge operation skills and management know-how. Third, the government succeeded in raising public asset values, and thanks to this, the government is able to consider other similar projects not only in the water sector but also other sectors in public utility services. Nevertheless, Berlin Water's point of view, there are several challenges. First, the company took a risk to pay such a large amount of cash to the Hefei government. Although such premium can be recouped in the operation period of 23 years, whether or not the company would be able to recover the initial investment and realize profits is in question due to an uncertainty of socio-political circumstances in China. Second, Berlin Water should expect a steep rise of water tariffs over the contract period in order to get the investment back. Water pricing is still a sensible matter to Chinese authorities, and therefore, it is uncertain if such rise of water tariffs would be possible. Third, the TOT mode leads to creation of a large amount of cash to government officials, which might have caused corruption between those who are involved in TOT deals. Then, the final contract fee would soar, which often results in the burden of normal customers. As discussed, the TOT mode has drawn much attention of foreign investors as a new alternative to enter into the Chinese water market. But it is important to note that foreign investors should be aware of possible risks in water TOT projects, which reflects some features of the Chinese political economy landscape and social norms. The Hefei case indicates that benefits can overshadow risks in TOT projects, which will continue to attract foreign investors that are dedicated to establishing their strongholds in the Chinese water market.

• The Korean Journal of Mycology
• /
• v.3 no.2
• /
• pp.1-6
• /
• 1975

Various enzymes produced by the Basidiomycetes, i.e. Pleurotus ostreatus, Pholiota nameko and Flammulina velutipes have been analysed. The purpose of the analyses is to produce a nutritious fertilizer from saw dust, sweet potato stems, corn stems and barley stems which are known as the farm product waste materials. The results of the analyses are as follows: 1. In order for P. ostreatus, Pho. nameko and F. velutipes to grow properly, the saw dust of broad-leaved trees, poplar and chestnut were mixed with sweet-potato stems, corn stems and barley straws at the ratio of $42{\sim}49\;:\;30$, and then to this mixture was added rice bran at the ratio of $18{\sim}35\;:\;30$ The following proved to be optimum conditions for the growth in this test: the parcentage of water content $60{\sim}70%$, $24{\sim}26^{\circ}C$ degrees of temperature. 2. We analyzed the fiber contained in the above materials after 20 days growth in various media. We found out that the fiber was decomposed up to $47{\sim}50%$ and polysaccharified. Lignin was decomposed up to $20{\sim}25%$ and about three times as much protein was contained in the product as in the original materials. 3. Our analyses revealed the possibility of producing concentrated feed from the crude fiber.

• Korean Journal of Oriental Medicine
• /
• v.2 no.1
• /
• pp.337-380
• /
• 1996

'Nei Jing(內徑)' first defined the interrelationship of the true and tile false between evil factor affecting health(雅氣) and vital essence energy(精氣). According to 「'Nei Jing(內徑)', the above interrelationship is explained as 'If state of evil domination is considered as sthenia-syndrome(雅氣盛則實), if the consumption of healthy energy Is considered as asenia-syndrome(精氣尊則虛): 'Nei Jing(內徑)', proposed major features of the medicall treatment by 'regluate the vatal energy of asthenia and sthenia, treat the sthenia-syndrome by purgation, and treat the asenia-syndrome by therapy of invigoration(調其氣之虛實, 實則瀉之, 虛則補之): The above interrelationship was interpreted as 'treat the asthenia-syndrome of child organ by invigorating the mother organ(虛者補其母)'in the 69th of 'The Classic on Difficulty',(難經 六十九難). Go-Mu(高武) of Myung-dynasty describe therapy for invigoration and purgation of itself-meridian(自經 補瀉法), which locating acupuncture points according to the Therorr of Five Element in the five shu points of itself-meridian(自經 五유穴), based on the generation in the ${\ulcorner}$A Synthetical Book of Acupuncture and Moxibustion(針灸聚英)${\lrcorner}$, Sae-hyun Jang(張世賢) further extended location acupuncture points of the five shu points to the other-meridian in the ${\ulcorner}$Gyeo Jung Do Ju Nan Gyung(校正圖註難經)${\lrcorner}$ Sa-Ahm's 5 Element Acupuncture Method(舍嚴五行鍼法) was originated in 1644, the middle of the Yi-dynasty. It linked the reinforcing and reducing in acupuncture therapy which incorporated tlle asthenia-syndrome and sthenia-syndrome of the hollow organs, based on principle of the Yin Yang 5 Element Theory(陰陽五行學說), not only to the generation in the 5 element(相生關係) but also to the restriction in the 5 element(相剋關係). Furthermore it was devised for the medical treatment by comning therapy for invigoration and purgation of itself-meridian(自經 補瀉法) with that of the other-meridian. Even though many original forms(正形) of the therapy for invigoration and purgation of the Yin Yang 5 Element Theory comply with the principle of the generation and the restriction based on the principle of the Yin Yang 5 Element Theory are abailable, variational forms(變形) are also recognized by examining the nature of the Sa-Ahm's 5 Element Acupuncture Method(舍嚴五行鍼法), For this reason, it is very difficult to understand the Sa-Ahm's 5 Element Acupuncture Method(舍嚴五行鍼法) thoroughly. therefore, those variational forms are obstacles for the beginners to study the Sa-Ahm's 5 Element Acupuncture Method. In order to understand the principle of the practical clinical application of the Sa-Ahm's 5 Element Acupuncture Method, this study investigated which principle was based on the variations of the locating acupuncture points' method for the acupuncture prescription.

• The KIPS Transactions:PartD
• /
• v.13D no.4 s.107
• /
• pp.455-462
• /
• 2006

Recently, the filtering approach using vector approximation such as VA-file[1] or LPC-file[2] have been proposed to support similarity search in high dimensional data space. This approach filters out many irrelevant vectors by calculating the approximate distance from a query vector using the compact approximations of vectors in database. Accordingly, the total elapsed time for similarity search is reduced because the disk I/O time is eliminated by reading the compact approximations instead of original vectors. However, the search time of the VA-file or LPC-file is not much lessened compared to the brute-force search because it requires a lot of computations for calculating the approximate distance. This paper proposes a new bitmap index structure in order to minimize the calculating time. To improve the calculating speed, a specific value of an object is saved in a bit pattern that shows a spatial position of the feature vector on a data space, and the calculation for a distance between objects is performed by the XOR bit calculation that is much faster than the real vector calculation. According to the experiment, the method that this paper suggests has shortened the total searching time to the extent of about one fourth of the sequential searching time, and to the utmost two times of the existing methods by shortening the great deal of calculating time, although this method has a longer data reading time compared to the existing vector approximation based approach. Consequently, it can be confirmed that we can improve even more the searching performance by shortening the calculating time for filtering of the existing vector approximation methods when the database speed is fast enough.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.12 no.10
• /
• pp.4648-4659
• /
• 2011

Korea experienced rapid urbanization due to high growth of economy. As people left the country and gathered in the city, the size of city has been expanded, resulting in unbalanced development of the land. In addition, it appears in diverse aspects from nationwide phenomenon to the local development in each city unit. In particular, it even tends to become social problems in the metropolitan cities. As a solution for it, this study conducts theoretical consideration on sustainability in the aspect of balanced urban development and suggests measures through analysis on Siheung-city. The result is as follows. First of all, comprehensive approach is required based on sustainability. It is required to derive balanced city development by expanding it to the social, cultural and economic aspects. Second, integrated management policy is required for the original city along with new development. It should be considered together with diverse social and physical aspects. Third, approach from the aspect of city planning is required through consideration on flat city expansion and connection with city space structural. Fourth, in order to foster balanced urban development, it is needed to grope for solutions for imbalanced urban development through the participation of diverse groups such as local residents, private enterprisers, and the non-profit civic groups of the local community along with the mediation among persons interested. And continuous support of administrative authorities should be obtained to create such environment.

• The KIPS Transactions:PartB
• /
• v.13B no.3 s.106
• /
• pp.337-344
• /
• 2006

In this paper, we describe the design and the implementation of word clustering system using a definition of an entry word in the dictionary, called a dictionary definition. Generally word clustering needs various features like words and the performance of a system for the word clustering depends on using some kinds of features. Dictionary definition describes the meaning of an entry in detail, but words in the dictionary definition are implicative or abstractive, and then its length is not long. The word clustering using only features extracted from the dictionary definition results in a lots of small-size clusters. In order to make large-size clusters and improve the performance, we need to transform the features into more general words with keeping the original meaning of the dictionary definition as intact as possible. In this paper, we propose two methods for extending the dictionary definition using ontology. One is to extend the dictionary definition to parent words on the ontology and the other is to extend the dictionary definition to some words in fixed depth from the root of the ontology. Through our experiments, we have observed that the proposed systems outperform that without extending features, and the latter's extending method overtakes the former's extending method in performance. We have also observed that verbs are very useful in extending features in the case of word clustering.