• 제목/요약/키워드: oriental medical materials

검색결과 230건 처리시간 0.036초

당뇨병성 말초 신경병증의 개괄과 한의학적 연구의 필요성 (Overview of Diabetic Peripheral Neuropathy and Need for Therapeutic Strategy using Traditional Korean Medicine)

  • 김진미;윤성식;안소현;최정식;조충식;손창규;김철중
    • 대한한의학회지
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    • 제30권5호
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    • pp.127-136
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    • 2009
  • Objective: This study aimed to analyze the current status of treatments and patients with diabetic peripheral neuropathy, and then map out of a strategy for development of generalized-treatments for diabetic peripheral neuropathy in Traditional Korean Medicine. Methods: We selected research materials from various databases such as PubMed, Google, KStudy, KoreanTK, OIM, KOMS and books. Also, to understand current tendencies of medical examination and treatment related with diabetic peripheral neuropathy, we requested Health Insurance Review and Assessment Service clinical data from 2003 to 2007. Results: It is reported that the incidence of diabetic peripheral neuropathy is increasing in an aging society. The medical fees of National Health Insurance related with diabetic peripheral neuropathy show a year-on-year increase. There are no particularly effective therapies for diabetic peripheral neuropathy in Western medicine, and in some papers, it was reported that treatment of diabetic peripheral neuropathy using Traditional Korean Medicine was effective. However, patients usually visit on Western medical center rather than seek Traditional Korean Medicine. To take charge of clinical fields related with diabetic peripheral neuropathy by Traditional Korean Medicine, we need more studies and experiments of diabetic peripheral neuropathy using Traditional Korean Medicine and should make a standardized protocol. Conclusion: Various studies related with diabetic peripheral neuropathy using Traditional Korean Medicine will have to be undertaken hereafter. We expect that Traditional Korean Medicine will play a vital role in treating of diabetic peripheral neuropathy.

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Inhibitory Effects of Fermented Gastrodia elata on High Glucose-induced NO and IL-8 Production in Human Umbilical Vein Endothelial Cells

  • Kwon, Se-Uk;Jeon, Sung-Bong;Xin, Mingje;Kim, Jun-Ho;Im, Ji-Young;Cha, Ji-Yun;Jee, Ho-Kyun;Lee, Oh-Gu;Kim, Dae-Ki;Lee, Young-Mi
    • Natural Product Sciences
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    • 제18권4호
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    • pp.266-272
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    • 2012
  • Hyperglycemia or high glucose (HG), is the hallmark of diabetes, known to induce oxidative stress, release of chemokines, and cytokines, which confer endothelial cell damage. On the other hand, microbial transformation of organic materials often leads to certain changes in their product structures which could enhance their biological activities. The aim of this study was to investigate the beneficial effects of fermented Gastrodia elata (FGE) in HG induced human umbilical vein endothelial cells (HUVECs) dysfunction. GE, fermented by Saccharomyces cerevisiae, which has an extensive history of safe use, exhibited higher phenolic compounds content than those of Gastrodia elata (GE). The HG-induced production of nitric oxide (NO) and interleukin-8 (IL-8) were significantly attenuated by FGE pretreatment to the cells, in a concentration dependent manner. In addition, FGE showed marked activity in free radical scavenging. These results suggest that FGE possesses beneficial effects in protecting against the oxidative stress, and inflammatory conditions in endothelial cells, caused by HG.

경피기주입술(Carboxytherapy)에 대한 문헌적 고찰 (Review of Literature on Chi Acupunture(Carboxytherapy))

  • 심우진;송재철;이종수;신현택
    • 한방비만학회지
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    • 제6권2호
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    • pp.43-49
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    • 2006
  • Objective : This study was conducted to offer basic materials for the clinical study of Chi acupuncture (carboxytherapy). Methods : Recent clinical studies were reviewed for carboxytherapy (carbon dioxide therapy) and the ancient and present texts were reviewed for Chi acupuncture. Results and Conclusions : Chi acupuncture is oriental medical therapeutic treatment using carboxytherapy. Chi acupuncture refers to the transcutaneous administration of CO2 gas for therapeutical purposes relating to obesity, cellulites, local circulation and skin irregularity. Recent studies have demonstrated the effects of this therapy on adipose tissue by showing vasomotor effects, increasing local circulation and inducing a partial increase in tcPO2. Chi acupuncture influences the microcirculation and likely has a positive effect upon the physiological oxidative lipolytic process.

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약인성 간손상의 원인물질에 관한 국내연구의 체계적 고찰 (Systematic Review of the Cause of Drug-Induced Liver Injuries in Korean Literature)

  • 윤영주;신병철;이명수;조성일;박재현;이혜정
    • 대한한의학회지
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    • 제30권2호
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    • pp.30-45
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    • 2009
  • Background: The safety of herbal products is an important issue in Korea. It is more complicated because of the concomitant use of conventional western drugs and herbal medicine, including prescribed medicine, folk herbs and food supplements. Although both western and traditional Korean medical doctors have studied on the safety of HMP, their results did not show relevant or consistent conclusions because of the poor quality of studies, including bias. Objectives: The aim of this study was to review the studies in Korea related to drug induced liver injury (DILI) systematically. We tried to estimate the proportion of causative materials of DILI and evaluate the clinical difference of DILIs from different materials. Methods: Systematic searches were performed on MedRIC and MEDLIS in Korea. The extraction of data as well as selective screening of the studies was carried out independently by two of the authors. There were no restrictions on the types of publication, including grey literature. Results: Twenty-one articles were included. Of them only 7 adapted prospective design and only 6 were published in peer-reviewed journals. The proportion of conventional drugs associated with hepatotoxic injuries in all DILI ranged from 15.8% to 83.3% and that of herbal medicine was from 28.9% to 44.7%. However, the criteria for herbal medicine were not clearly defined and concomitant medications were not fully investigated in most studies. There were limited objective data in the clinical differences of liver injuries from different materials and their results were conflicting. Conclusions: The causality assessments regarding DILI of herbal medicine were not performed properly and causative materials were misclassified in most of the studies published in Korea. These make the safety issue still ambiguous because of the limitations and lack of objectivity of the studies. More rigorous studies are required for clearly addressing these conflicting issues with cooperative investigation between traditional Korean and western medicine.

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한의학과 문학의 교섭 양상 연구 -약명시(藥名詩)를 중심으로- (A Study on Reciprocal Relationship between TKM and Literature : Centering on Medicinal Name Verses(YakMyeongSi))

  • 이정현
    • 한국한의학연구원논문집
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    • 제16권3호
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    • pp.77-84
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    • 2010
  • In this study, YakMyeongSi were considered to define relations of Tradional Korean Medicine(TKM) and literature. In the introduction, present related studies were searched to clarify YakMyeongSi are completely different from medical property songs(YakSeongGa). Related data about YakMyeongSi and YakSeongGa were extracted for the initial findings. In chapter 2, medical name verse was defined as 'a type of free verses with one or more medical names in each verse to be interpreted ordinarily' based on records and examples of YakMyeongSi. In China, it originated from "Book of Odes" and "Songs of Chu", and it was most popular in the Song-China. Medical names actually referred to medical names in the early forms of the Warring States Period, but the complete form of YakMyeongSi started to appear in the Tang-China. In chapter 3, 34 YakMyeongSi and 5 related data were suggested in tables as the present conditions of Korean YakMyeongSi. With actual examples, better comprehension of YakMyeongSi were intended. Also, the fact that Korean YakMyeongSi were completed in forms at the end of Goryeo and beginning of Joseon dynasty. The motivations of writing YakMyeongSi were also studied. Medical names were put into verses because they well expressed landscapes and emotions. Propagation of medical knowledge was the basis of YakMyeongSi. There are limits in defining the relations of TKM and literature with some YakMyeongSi. More studies must be carried out on YakMyeongSi in various records with details and interests. Also, study to define general relations of TKM and literature must be carried out together by examining TKM in literary forms such as medical introductions or medical property songs and literature pieces that expressed principles and materials of TKM.

"우잠잡저(愚岑雜著)" 소재(所在) 광증(狂證) 이안(二案)에 관(關)한 연구(硏究) (A Study on two cases of Insanity in "WooJam JabJeo(愚岑雜著)")

  • 박상영;권오민;이정화;오준호
    • 대한한의학원전학회지
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    • 제24권6호
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    • pp.101-110
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    • 2011
  • There are not a few cases in Oriental medicine where a different prescription should be given to some of the patients whose symptoms are similar to each other. In other words, there might happen a misdiagnosis due to an extremely delicate difference in symptoms of the same diseases, causing a patient's condition to get worse or to be even on the brink of death. In such a context, the records in "WooJam JabJeo(愚岑雜著)" are worthwhile to do in-depth research on. Jang-Taegyung described his first-hand experience in major medical treatment very vivaciously during his ages between 25 and 42. Particularly, most of the prescriptions recorded in this book include not only his empirical prescriptions on the patients who life was almost on the brink of death but it also so plentifully contained the process of overcoming the side effect caused by other clinics' misdiagnosis; thus, that this book is drawing attention in that it could be indispensable materials not only in the research on medical history but also for clinical treatment. Particularly, as regards two cases of insanity, this book mentions the reason for using totally different prescription on one case from the other case even though the two cases had a similar symptom, through which we can acquire somewhat concrete experience in curing scenes though indirectly during the period of the Joseon Dynasty. We were able to get the result from the analysis of the two cases of insanity as follows: 1. WooJam, in treating the two cases of insanity due to the severe exacerbation of yang energy, managed to treat the one case by inducing a bowel movement and the other case by inducing urination. Such a different treatment seems to be greatly attributable to the constitutional factor of the two patients. Such an Oriental-medicine-based method of diagnosis and prescription as WooJam's is rarely found in Western medicine-i.e., that's why more thorough research on Oriental medicine is deeply required. 2. In case of the second patient, the patient arrived at insanity due to another clinic's treatment on perspiration on the patient with severe mouth thirst. This medical story once again highlights the importance of a diagnosis in today's Oriental medicine and at the same time it's a good example showing how big the side effect caused by the abuse of medicinal herbs is. The second patient's body fluids ran dry and finally his yang energy got exacerbated all the more due to the treatment by perspiration.

오미약성이론을 활용한 황련, 승마, 백복령 및 복합물의 생리활성 (Physiological Activity of Coptis japonica, White Poria cocos, and Cimicifuga heracleifolia and a Mixture of Their Extracts on Skin Based on The Oriental Medicine OMiYakSung Theory)

  • 유화선;오성화;이정노;김희택;하헌용;김용민;박성민
    • 대한화장품학회지
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    • 제45권1호
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    • pp.77-85
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    • 2019
  • 오미약성 이론은 다섯가지 맛 중에서 적어도 하나 이상을 맛을 포함하는 다양한 허브로 구성되어 있으며, 이러한 이론은 인간의 질병을 예방하고 면역 체계를 강화하는데 사용되어왔다. 본 연구의 목적은 오미약성 이론에 근거한 단일 추출물 및 혼합 추출물의 효능 차이와 성분 변화를 확인하는 것이다. 황련, 승마 및 백복령 세가지 약초를 선택하였고 단일 추출물 및 혼합 추출물의 약리학적 효능을 평가하였다. 결과적으로 혼합추출물은 단일추출물과 비교하여 400 ug/mL 농도에서 우수한 세포 이동 효과를 보였다. 또한 혼합추출물은 수지상세포의 활성을 증가시켜 면역을 강화시켰으며 DPPH assay 및 HPLC-ABTS assay를 통해 가장 높은 항산화 활성을 보였다. 이번 연구에서 우리는 한의학적 이론을 접목하여 화장품 및 의약품 분야에 응용 가능한 새로운 소재를 개발하였다.

유가사상(儒家思想)에 바탕을 둔 한의학에서의 의료윤리 (Medical Ethics based on Confucian Ideas in Eastern Medicine)

  • 김근우
    • 동의신경정신과학회지
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    • 제20권3호
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    • pp.149-168
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    • 2009
  • Objectives : This study aimed for attain to ideal aspects in medical ethics-clinical medicine, through researching doctor's ethics based on Confucian ideas, Methods : Research materials are datum of Confucian ideas included eastern medical books and the Confucian old books, Stand on above-mentioned, I investigate indispensable ethical condition clinical doctor must have in diagnose and treat. Results and Conclusions : 1. Combination of people-oriented ideas-Confucian and applicative learning-Eastern Medicine, doctor's principle mind is initiated and Confucian physician is the center of that. 2. For practice morality and ethics using the Confucianist's good character, Eastern medical doctor read and acquire the Confucian books. 3. Eastern medical doctor make an effort for application a kind love ideas(perfect religious scholarship ideas of Confucian), serve parents and country as for practice and sublimate into a kind love ideas through practice of integrity and the self-sacrifice. 4. Occasion to examine the female patient, emphasize good manners by Confucian ideas's sexual distinction 5. According to the doctor-doctor ethics, partnership is important due to Confucian faith and good manners 6. Confucian physician often effected by the people around patient and the protector of patient and criticize positive influence by these kind of peoples(傍人) when diagnose and treat. 7. Owing to Confucian's a notion of preferring a son to a daughter(男兒選好思想), come out the methods of convert a son into a daughter(轉女爲男法)-manipulation of sex distinction. this method is criticized aspect of medical ethics.

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한의학의 항종양 면역치료에 관한 연구 -1990년 이후 발표된 실험논문을 중심으로- (Compilation of 104 Experimental Theses on the Antitumor and Immuno-activating therapies of Oriental Medicine)

  • 강연이;김태임;박종오;김성훈;박종대;김동희
    • 동의생리병리학회지
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    • 제17권1호
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    • pp.1-24
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    • 2003
  • This study was done to compile 104 experimental theses which are related to the antitumor and immuno-activating therapies between February 1990 through February 2002. Master's and doctoral theses were dassified by schools, degrees, materials, effects, experimental methods of antitumor and immunoactivity, and results. The following results were obtained from this study : 1. Classifying the theses by the school, 34.6% were presented by Daejeon University, 29.8% by Kyung-hee University and 11.5% by Won-kwang University. Of all theses, 51.0% were aimed for the doctoral degree and 43.3% were for the master's degree. All of three universities have their own cancer centers. 2. Classifying the theses by herb materials, complex prescription accounted for 60.3%, single herb accounted for 24.8% and herbal acupuncture accounted for 14.2%. Considering the key principles of the traditional medicine, complex prescription was much more thoroughly studied than single herb prescription. The results showed that the complex prescription had both antitumor activity and immuno-activating activity, which might reflects on multi-activation mechanisms by complex components. 3. Classifying the theses by the efficacy of herbs examined, in single herb, invigorating spleen and supplementing was 35.5%, expelling toxin and cooling was 29.0%, activating blood flow and removing blood stasis was 12.9%. In herbal acupuncture, invigorating spleen and supplementing was 52.9%, expelling toxin and cooling was 29.4%. In complex prescription, pathogen-free status was 41.9%, strengthening healthy qi to eliminate pathogen was 35.5%, strengthening healthy qi was 22.6%. It is presumed that the antitumor and immunoactivating therapy based on syndrome differentiation is the best way to develop oriental oncology. 4. Classifying the theses by antitumor experiments, cytotoxic effect was 48.1 %, survival time was 48.1 % and change of tumor size was 42.3%. Survival rate was not necessarily correlated with cytotoxicity. These data reflect the characteristic, wholistic nature of the oriental medicine which is based on BRM (biological response modifier). 5. Classifying the theses by immunoactivating experiments, hemolysin titer was 51.0%, hemagglutinin titer was 46.2% and NK cell's activity was 44.2%. In the future studies, an effort to elucidate specific molecular and cellular mechanisms of cytokine production in the body would be crucial. 6. Classifying the theses according to the data in terms of antitumor activity, 50% was evaluated good, 24.0% was excellent, and 15.5% have no effect. In an evaluation of immuno-activating activity, 35.9% was excellent and 18.0% showed a little effect. The index point, as described here, may helps to use experimental data for clinical trials. Changes in index points by varying dosage implicate the importance of oriental medical theory for prescription. 7. In 167 materials, IIP (immunoactivating index point, mean : 3.12±0.07) was significantly higher than AIP(antitumor index point, mean : 2.83±0.07). These data demonstrate that the effect of herb medicine on tumor activity depends more on immunoactivating activity than antitumor activity. This further implies that the development of herbal antitumor drugs must be preceded by the mechanistic understanding of immunoactivating effect. 8. After medline-searching tumor and herb-related articles from NCBI web site, we conclude that most of the studies are primarily focused on biomolecular mechanisms and/or pathways. Henceforth, we need to define the biomolecular mechanisms and/or pathways affected by herbs or complicated prescriptions. 9. Therefore, the most important point of oriental medical oncology is to conned between experimental results and clinical trials. For the public application of herbal therapy to cancer, it is critical to present the data to mass media. 10. To develop the relationship of experimental results and clinical trials, university's cancer clinic must have a long-range plan related to the university laboratories and, at the same time, a regular consortium for this relationship is imperative. 11. After all these efforts, a new type herbal medicine for cancer therapy which is to take care of the long-term administering and safety problem must be developed. Then, it would be expected that anti-tumor herbal acupuncture can improve clinical symptoms and quality of life (QOL) for cancer patients. 12. Finally, oriental medical cancer center must be constructed in NCC (National Cancer Center) or government agency for the development of oriental medical oncology which has international competitive power.

Essential Oil Prepared from Cymbopogon citrates Exerted an Antimicrobial Activity Against Plant Pathogenic and Medical Microorganisms

  • Jeong, Mi-Ran;Park, Pyeong-Beom;Kim, Dae-Hyuk;Jang, Yong-Suk;Jeong, Han-Sol;Choi, Sang-Hoon
    • Mycobiology
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    • 제37권1호
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    • pp.48-52
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    • 2009
  • Essential oils are mixtures of volatile, lipophilic compounds originating from plants. Some essential oils have useful biological activities including antimicrobial, spasmolytic, antiplasmodial, and insect-repelling activities. In this study, we tested the antimicrobial activity of essential oil prepared from the aromatic plant, Cymbopogon citrates, against three important plant pathogenic and medical microorganisms, Pectobacterium carotovorum, Colletotrichum gloeosporioides, and Aspergillus niger. It effectively inhibited the growth of the bacterium, Pectobacterium carotovorum, in a dose-dependent fashion, and 0.5% of the oil inhibited the growth of bacteria completely. Similarly, the essential oil inhibited the growth of plant pathogenic fungus, Colletotrichum gloeosporioides, and the addition of 1% of essential oil completely inhibited the growth of fungus even after 5 days of culture. Finally, it effectively inhibited the growth of the medically and industrially important fungal species, Aspergillus spp. These results suggest that the essential oil from Cymbopogon citrates may be an environmentally safe alternative to inhibit antimicrobial agents for various uses.