• 동의신경정신과학회지
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• 제19권1호
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• pp.125-146
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• 2008

Objectives : The purpose of this study is to suggest for the following experimental study of dementia by reviewing recent oriental medicine journals that have been published since 2000. Methods: We have investigated various types of studies in relation to dementia through 90 articles that have been published from 2000 to 2007 in recent oriental medicine journals were registered Korea research foundation. Results and Conclusions : 1. Since 2000, 88 articles in relation to dementia have been published and almost of them are herbal medicine-centered studies. Also they show a tendency to increase every year. The journal of oriental neuropsychiatry carries the highest number of studies in relation to dementia. 2. According to the experimental paper, there are 30 cases of using herb simplexes, 48 cases of herb-combined prescription, and 10 cases of other ways. Especially 7 cases of using herb-combined prescription relation to Sasang constitution are all for the Taeumin. 3. There are 85 cases of Animal and cellular experimental, 60 cases of using pathologic model induced cytotoxic activity, a case of using L-NAME, 3 cases of 192 saporin, 4 cases of ibotenic acid, 10 cases of focal cerebral ischemia, 3 cases of alcohol-administered, and one case of natural degradation. 4. Moms water maze, Radial arm maze Passive avoidance learning model were using for examining learning and memory of model animal 5. We propose that following studies of dementia are to he investigated of the applied method of using siRNA with tranceduced gene, sample preparation by water-soaking, oriental medical diagnosis, standardization of differentiating symptom and herb simplexes, building the database by classified prescriptions, and experiment model which are based on precise examining mechanism with cell line as like mouse H19-7 hippocampus, rat HT22 hippocampus, astrocyte, microglia, using the model of animals at APP, PS1, BACE, CT99/PS1, APOE4, Tau, APP/PSI/Tau

• 대한한방내과학회지
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• 제27권2호
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• pp.336-344
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• 2006

Objects : This study has been carried out to assess the effects of the variable herbs on $IFN-{\gamma}$ secretion in the mouse spleen cell. Methods : 202 kinds of herb extracts were used to evaluate the $IFN-{\gamma}$ secretory distinction by each $1{\mu}g/ml$ and $10{\mu}g/ml$ density of water. All experimental herbs were grouped by oriental herbalogical method. But each herb had its independent variables. Results : The secretions increased in 20% of all herbal water. The density differences also make different effects on the secretion of $IFN-{\gamma}$. The secretion of IFN-${\gamma}$ inclosed in some kinds of herbs of IFN-${\gamma}$. It has representatively increased in Imperaetae Rhizoma(白茅根) of $1{\mu}g/ml$ and Notopterygii Rhizoma(羌活)of $10{\mu}g/ml$. $IFN-{\gamma}$ incresed in 12 kinds of heybs of both densities. The secretion of $IFN-{\gamma}$ decreased in some kinds of herbs of $IFN-{\gamma}$. It has representatively decreased in Moutan Radicis Cortex(蘇丹皮) of $1{\mu}g/ml$ and Angelicae Radix(富歸尾) of $10{\mu}g/ml$. $IFN-{\gamma}$ decreased in 18 kinds of herbs of both densities. In t oriental herb group, The secretion of $IFN-{\gamma}$ increased in Bang-Hyang-Hwa-Sup group(芳香化濕藥), He-Pyo group(解表藥), I-Su-Sam-SuP group(利水渗) The secretion of $IFN-{\gamma}$ decreased in Gu-Chung group(驅蟲藥), An-Sin group(安神藥). Su-Sap group(收澁) On-Li group(溫裏藥), I-Gi group(利氣藥). Conclusions : The result of this study will not only broaden applications of oriental medicine to biological therapy, but also form the basis of oriental medical therapy to find out the meaning of oriental classification.

• Korean Journal of Acupuncture
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• 제30권2호
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• pp.88-96
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• 2013

Objectives : In the acupuncture treatment of Korean Medicine, the Tonifying or Purging depending on how many times the needle is rotated has been used widely. However, there is little evidence about the optimal number of rotation. This study, therefore, was aimed to investigate the optimal number of rotation. Methods : Heart rate variation was measured before and after exercise in 20 healthy adults. Acupuncture was performed at PC6 immediately after exercise according to the protocol of each group without remaining. Pre-exercise and post-exercise measurements were compared and the rotation number that produced statistically significant difference was investigated. Results : Significant differences were found in the heart rate variation and R-R interval Average, between non-rotation group (control) and both of 15 times rotation group of tonifying and 6 times rotation group of purging. Conclusions : Significantly effective number of rotation in the effect of PC6 on the HR and RRAv was 15 times in the tonifying and 6 in the purging respectively.

• 대한한방내과학회지
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• 제15권1호
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• pp.210-226
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• 1994

This study was performed to investigate the gastric cancer through the journal of oriental medicine since 1990. The following results have been obtaied. 1. The Herb-medication in Gastric Cancer was composed to the oral-method and the injection-method. but, the oral-method was major and the injection-method rarely used. 2. In the treatment of Gastric Cancer, the Herb-medication that copperated with the operation and chemotherahpy was much more used 3. In the oriental medical therapy, the therapy for invigoration(補法) was common used. and the therapy for regulating vital energy(理氣), removing blood stasis(祛瘀), relieving pain(止痛), clearing away the heat evil (淸熱), removing toxic material(解毒) was used. 4. The following Herb was much more used to threat the Gastric Cancer.

• 사상체질의학회지
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• 제13권2호
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• pp.190-193
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• 2001

A 33-year-old woman diagnosed as livedo reticularis came to this hospital on October 14th, 1995. She complained of cold feet, ulceration on both ankles at the first OPD visit. We have diagnosed as 'Taeumin Ban-Chang-Byoung'. And we have applied acupunctures(Auricular Acupuncture + Acupuncture) and herb durgs. Auricular acu-points are Heart, Lungs, Shenmen, Adrenal. Herb drugs are Yuldahansotang or Chengpesagantang. After 3 treatments, she felt her feet warm. After 32 treatments, ulceration has disappeared. Even though we can't say that Ban-Chang-Byoung is livedo reticularis. But we can assume that two are related on the basis of the context of 'Dongyisoosebowon'.

• 동의신경정신과학회지
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• 제22권2호
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• pp.177-198
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• 2011

Objectives : By analyzing and comparing indications, components and their doses of herb medicines, which were recorded in insomnia chapters of medical books, we examined historical changes and made clear documentary ground of medications. Methods : 1. 10 books which were noted in insomnia part of "The Eastern Medical Textbook of neuropsychiatry" and 13 books were mentioned in same part of "Uibujeonrok" were selected as reference. 2. We searched article database such as KISS, riss4U and journals issued by the Korean society of oriental neuropsychiatry. Finally, 39 books which were noted in 3 literature reviews, were chose as reference. 3. In reference books, we collected the herb medicines in chapters related to insomnia. 4. In case of no section associated with insomnia in books, we found prescriptions related to insomnia in whole chapters. 5. If the chief virtue of medication was not primarily for insomnia, we excluded applied or added herb medicines. 6. We classified prescriptions into small groups which had same name, and then rearranged them in chronological order. Results and Conclusions : 1. Banha-tang(banxiatang) of "Hwangjenaegyeong Youngchu" was the first-recorded prescription used for insomnia. 2. The chapter of insomnia appeared in "Chunkeumyobang" at first. 3. Ondam-tang(Wendantang) was most cited prescription in medical books. It was recorded totally 19 books from "Chunkeumyobang" to "Hyeoljeungron". 4. We suspects indications, components, dosage of medication of insomnia in Donguibogam were revised according to author's clinical experience and circumstances.

• Journal of Acupuncture Research
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• 제18권1호
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• pp.146-156
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• 2001

Objectrve : To research the trends of the study related to aging process, and to establish the direction of the study on aging process. Method : We reviewed the journal and essay about the aging process which are published as well in Korea as in foreign country. Results : 1. The study on the Oriental Medicine field can be classfied with the fourth. first, the study of single herb medication's effect on the aging process. second, the study of multiple herb medication's effect on the aging process. third, the study of herb-acupuncture solution's effect on the aging process. fourth, journal review. We find the fact that the study on the Oriental Medicine is concerned with pathology of deficiency syndrome of the kidneys, retention of phlegm and fluid, blood stasis. 2. On the Western Medicine field, mechanism and pathology of aging pracess primarily has been studied. The mechanism of aging process is classified with 'Wear and tear theory' and 'Genome-based theory'. Among the mechanism of aging process, 'Free radical theory' is the most important. Additionally 'Senescence-Accelerated Mouse' has been studied. 3. We review the journal published in foreign country and its subject was the following: first, moxibustion combined with acu-area skin allograft therapy for the aging was effective, second, the traditional chinese medicine bu-zhong-yi-qi-tang in mice have anti-aging effect. third, the overview Preventive geriatrics of Traditional chinese medicine. 4. We researched anti-aging effect study in the journal of the Korean Acupuncture and Moxibustion, and we found a few journal of Herb-acupuncture solution's anti-aging effect. Hereafter, it is necessory that we will study about relationship between acupuncture-moxibustion therpy and anti-aging effect using Senescence-Accelerated Mouse.

• 농업생명과학연구
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• 제50권5호
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• pp.81-93
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• 2016

지황은 현삼과(Scrophulariaceae)에 속하는 다년생 초본식물 Rehmannia glutinosa(Gaertn.) DC.로서 한의학에서는 뿌리를 지황(地黃)이라는 한약재로 이용하고 있다. 지황은 선지황(鮮地黃), 생지황(生地黃), 숙지황(熟地黃) 등으로 널리 사용되고 있지만 종자파종에 의한 재배보다 종근을 이용한 영양번식으로 재배하고 있다. 종근을 이용한 재배법은 뿌리 썩음병으로 인해 종근의 관리와 생산성이 높은 고품질의 지황 생산이 어려운 실정이다. 본 연구에서는 형태적 특징과 유전자 분석을 통해 기원이 검증된 지황 기원식물을 이용하여 정확한 기원의 무균 배양묘와 종근 생산을 위한 최적 조건을 확립하고자 하였다. 기내배양묘 생산에 필요한 최적의 생장율과 다개체 형성율, 그리고 뿌리 형성율 및 비대조건을 탐색한 결과, WPM 배지와 1.0mg/L의 IAA와 0.5mg/L의 IBA 옥신계 생장조절제가 첨가된 배지(WPM + IAA 1.0mg/L + IBA 0.5mg/L)에서 최적 생장율과 뿌리다개체 형성율을 나타내었으며, 0.1mg/L의 NAA가 첨가된 WPM 배지(WPM + NAA 0.1mg/L)에서 가장 많은 수의 뿌리가 형성되었고 비대율도 높게 나타났다. 이러한 최적조건에서 생산한 기내식물체는 토양 순화 후 정식하였을 경우에도 높은 뿌리형성율과 지속적인 비대 효과를 보였다. 이상의 결과는 지황의 무균 배양묘 생산과 배양묘기반 종근 생산을 통해 지황 대량 생산에 필요한 배양묘와 종근 생산에 유용하게 활용될 수 있을 것으로 판단되며, 고품질 지황 생산량에기여할 것으로 사료된다.

• 한국한의학연구원논문집
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• 제14권2호
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• pp.1-10
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• 2008

Noh Jungrye(盧重禮) can be cited as an representative royal doctor of early Chosun dynasty. He collaborated in the development of korean medicine out of the influence of chinese medicine. He made an systematical approach on supply and propagation of The Native Herb Medicine(鄕藥) which promoted the independence of Korean medicine. The edition of "HyangYakJibSungBang(鄕藥集成方)"(Compendium of Prescriptions from the Countryside) was the result of this effort establishing the originality of Korean medicine. He also strengthened in the medical support new born child editing "TaeSanYoRok(胎産要錄)" as their mortal rate was high in that time. In social-political aspect, being appointed in Dangsanggwan(堂上官) as a doctor, was controversial as even after his death this discussion kept on. On the other hand this designation prompt other doctors to devote in Korean medicine.

• 동의생리병리학회지
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• 제21권6호
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• pp.1641-1645
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• 2007

This study was designed to investigate about the efficiency of herb treatment at the patients with urinary tract infection. The Patient group was consisted of 33 CVA patients who were diagnosed as abnormal on urinalysis at the Oriental Medical hospital of Dong-eui University from July in 2006 to April in 2007. And we divided the patient group to 3 of small groups(Bojungikitang, Kumokpaljungsan, and the others herb). Then we treated the patients with each herbs and checked urinary nitrate, leukocyte, bacteria, WBC after 3 days, 7 days. The results are as follows: Each herbs improved the results of urinalysis inspection. The efficiency of each herbs about UTI begins to be indicated after 3days. Each herbs applied to UTI is more effective after 7 days than after 3 days. As the results, the herb treatments improve effectively the result of urinalysis inspection when precsribing to UTI patients more 7 days.