• 한국산업정보학회논문지
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• 제17권6호
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• pp.59-72
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• 2012

단백질은 서열의 disorder 구역이 생물학적 반응을 일으켜 order로 변하는 과정에서 그 기능을 하게 되므로 서열 데이터에서 disorder 구역과 order 구역을 분리하는 것은 단백질의 3차 구조 및 특성을 예측하는데 반드시 필요하다. 따라서 이 논문에서는 효율적인 disorder와 order 구역 분류를 위해서 단백질의 특정 특징에 치우치지 않는 분류 결과를 얻으면서, 분류 속도를 향상 시킬 수 있도록 서열 데이터를 이용한 분류/예측 기법을 제안한다. 출현패턴 기반의 EPs-TFP 기법은 중복 출현패턴이 제거된 필수 출현패턴만을 이용하는 분류/예측 기법이다. 이 분류 기법은 disorder 구역의 서열 출현패턴들을 발견하며, 이러한 서열 출현패턴은 disorder 구역에서는 빈발하지만 order 구역에서는 상대적으로 빈발하지 않는 패턴들이다. 또한 제안 알고리즘의 성능 향상을 위해서 기존의 P-tree, T-tree 개념의 TFP 기법을 확장하여 분류/예측 기법으로 적용하였다. EPs-TFP 기법의 성능평가를 위해서 Disprot 4.9와 CASP 7 데이터를 활용하였고, disorder/order 구역을 분류한 결과, 민감도 73.6, 특이도 69.5, 정확도 74.2를 보였다.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2011년도 춘계학술발표대회
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• pp.1274-1277
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• 2011

단백질 1차 서열로부터 DISORDER와 ORDER지역을 예측하기 위해서 이 논문에서는 EP-tree에 기반한 출현패턴 발견 알고리즘을 제안하였다. EP-tree 알고리즘을 적용함으로서 기존의 단백질 특징 추출을 통한 방법과 달리 서열 자체에서 발견되는 출현패턴만을 이용하여 분류 모델을 생성하므로 기존의 신경망이나 SVM 보다 분류모델 생성 및 예측 속도가 빠르다. 또한 Disprot 4.9과 CASP7 테스트 데이터로 DISORDER/ORDER 지역을 예측한 결과, 73.4%의 높은 정확성을 보였다.

• 대한임베디드공학회논문지
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• 제10권1호
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• pp.33-40
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• 2015

The number of people who are suffering from chronic sleep disorder has been growing dramatically in modern era. In order to diagonse the sleep disorder, sleep doctors perform polysomnography: Patients sleep with attaching several vital sign sensors on their body, and doctors monitor the patients in order to find the exact reason of the sleep disorder. Typical polysmonography makes patients sleep with several sensors on their bodies, which prevents the patients from making a comfortable sleep. Furthermore, it is impossible to have a long-term monitoring since the measurements should be done in sleep hosiptal within a few hours. In order to tackle these problems in the typical polysomnography, we envision the development of a non-contact long-term home polysomnography system using UWB radar and related technologies such as multi-modal signal processing.

• 동의신경정신과학회지
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• 제34권2호
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• pp.61-69
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• 2023

Objectives: To examine the effect of complex Korean medical treatment on tic disorder in children who visited the neuropsychiatric clinic of Korean medicine. Methods: Medical records of 35 patients diagnosed with tic disorder based on DSM-V who received complex Korean medical treatment (herbal medicine, acupuncture and Korean psychotherapy) were reviewed. Tic disorder was then evaluated by Yale Global Tic Severity Scale (YGTSS) before and at 4, 8, and 12 weeks after treatment to determine whether their symptoms were improved. Results: 1) After the treatment, mean YGTSS was reduced from 35.54±14.77 to 23.20±12.65. There were statistically significant changes between scores according to the time of treatment (p< 0.05). 2) At the time of visit, symptoms of motor tics were in the order of eyes, neck and shoulders, mouth, head and arms & hands, nose, face, upper body and other parts, and legs and symptoms of vocal tics were in the order of sniffing, dry coughing and MMM, AA and whistling, and other sounds. 3) For 35 patients, herbal medicine was prescribed every two weeks. The frequency of prescriptions used was in the order of Shihogayonggolmoryo-tang, Gami-ondam-tang, and others. 4) The frequency of herbs used in 35 patients was in the order of Poria, Zingiberis Rhizoma Recens, Pinelliae Rhizoma and Scutellariae Radix, Bupleuri Radix, Ostreae Concha and Bovis Ossis Fossilia, and others. Conclusions: Complex Korean medical treatment including herbal medicine, acupuncture, and Korean psychotherapy is effective for reducing tic symptoms in children.

• 한국보건간호학회지
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• 제22권2호
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• pp.165-176
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• 2008

Purpose: This study was conducted in order to analyze the factors that influence alcohol use disorder in elders in KyongBuk province. The results of the study will provide basic information for the development of nursing interventions to promote proper alcohol use in elders. Methods: The subjects were 626 elderly individuals. Alcohol use disorder was defined as a score of more than 15 point on the AUDIT-K(Korean version of Alcohol Use Identification Test). Descriptive statistics, chi-square test, ANOVA and logistic regression were utilized to analyze the data. Results: Overall incidence of alcohol use disorder level; normal 73.2%, problem drinking 7.5% and alcohol use disorder 19.3%. Significant factors affecting alcohol use disorder were sex (OR=6.897), religious belief (OR=1.836), smoking (OR=2.948), liver disease (OR=4.753) and depression (OR=1.779). Conclusion: Community health care nurses perform a crucial function in the screening of elderly alcoholics. Early detection and treatment of depression in elders may help to prevent alcoholism.

• 대한한의진단학회지
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• 제14권1호
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• pp.36-43
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• 2010

Objectives: Since we found patients with dyspepsia as their major symptom had high rate of headache, would like to find out a rational diagnosis ground by using EAV correlation between headache and gastrointestinal disorder Methods: We did survey and EAV inspection on 128 patients came by gastrointestinal disorder who quoted 4 and 5 degree for their headache symptoms) Results & Conclusion The results of this study were as follows: 1. From dyspepsia, we saw higher rate by order of epigastric discomfort, bloating, stomach trouble, bleching, etc. 2. By EAV analysis, found functional deterioration by order of stomach, nerval degeneration vessel, gall bladder/bile duct, liver. 3. By EAV analysis, functional deterioration of stomach, gall bladder/bile duct, liver represent dyspepsia and nerval degeneration vessel represent headache. We found the correlation between dyspepsia and headache by observation at a time.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2011년도 춘계학술발표대회
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• pp.6.2-6.2
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• 2011

Block copolymer (BCP) self-assembly in a film geometry has recently been the focus of increased research interest due to their potential use as templates and scaffolds for the fabrication of nanostructured materials. The phase behavior in a thin film geometry that confines polymer chains to the interfaces will be influenced by the interfacial interactions at substrate/polymer and polymer/air and the commensurability between the equilibrium period (L0) of the BCP and the total film thickness. We investigated the phase transitions for the films of block copolymers (BCPs) on the modified surface, like the order-to-disorder transition (ODT) by in-situ grazing incidence small angle x-ray scattering (GISAXS) and transmission electron microscopy (TEM). The selective interactions on the surface by a PS-grafted substrate provide the preferential interactions with the PS component of the block, while a random copolymer (PS-r-PMMA) grafted substrate do the balanced interfacial interactions on the surface. The thickness dependence of order-to-disorder behavior for BCP films will be discussed in terms of the surface interactions.

• 한국약용작물학회지
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• 제17권6호
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• pp.439-444
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• 2009

This study was to set the guidelines of soil chemical components in order to assure the safety and quality of the panax ginseng from physiological disorder. The disorder symptoms appeared on the leaf with yellow spot, atrophy, yellow-brown spot, also showed red skin and rough skin of the root. Occurrence type of physiological disorder in cultivated field divided into two types : type I 'such as, yellow spot' consist of single disorder symptom; type II 'such as, yellow spot and yellow-brown spot' consist of two or more different disorder symptoms. The individual contribution of soil properties to the occurrence type was as follows ; The yellow spot was affected by Na > $NO_3$-N > salinity (EC) in soil. The same results was observed in red skin. Atrophy was affected by $NO_3$-N > salinity (EC) > Ca > Mg. Rough skin was affected by $P_2O_5$>pH>Organic material > K. It showed positive associated to $P_2O_5$, pH and K, but negative associated to organic matter. Simultaneous occurrence of two different disorder, including cases which yellow spot and yellow-brown spot, those were affected by $NO_3$-N > salinity (EC) > Na > Mg. In the case of atrophy plus yellow-brown spot, those also were affected by in the order : $NO_3$-N > salinity (EC) > Ca > Mg > Na. Red-rough skin was affected in the order : salinity (EC) > $NO_3$-N > K > Na. Soil chemical components appear to be related to occurrence of physiological disorder, particularly in salinity (EC) and $NO_3$-N. The salinity (EC) and $NO_3$-N were negative related to plant growth. In addition, exchangeable cation capacity play critical roles in attributing to complex occurrence of physiological disorder.

• 동의신경정신과학회지
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• 제13권2호
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• pp.41-56
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• 2002

The Analysis of MMPI and Clinical Study was carried out the 28 patients with somatoform disorder and depressive disorder who were treated in Daejeon University Oriental Hospital from 19 June 2001 to 17 April 2002. The results were summarized as follows. 1. The ratio of female was higher, especially in the depressive disorder, the ratio of female was higher and in the age distribution, the 40 aged were higher frequence. 2. In the somatoform disorder, symptoms appeared to be busy in physical symptoms, and they were in descending order the digestive organs system, head and face portion and musculoskeletal system symptoms, in the depressive disorder, appeared to be busy in psychosomatic system symptoms and in the prescription drugs, soyosan(逍遙散), punsimkiyyin(分心氣飮) were used to be busy. 3. In the scales of L, F, K, somatoform disorder showed ${\wedge}$ typed graph, and depressive disorder showed ${\vee}$ typed graph. 4. In the somatoform disorder, scales of Hs, Hy, D, Pa were higher, and in the depressive disorder, scales of Hy, Hs, Pd, D were higher. 5. In the scales of Hs, D, Hy, somatoform disorder showed ${\vee}$ typed graph, and depressive disorder showed/typed graph. 6. the average of T-scores and the ratio over 65 score and 70 score showed common distribution.

• 한국진공학회:학술대회논문집
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• 한국진공학회 1999년도 제17회 학술발표회 논문개요집
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• pp.179-179
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• 1999

Cu3AU(100) 단결정은 fcc 구조를 가지고 있으며 (100)면은 Cu와 Au가 1:1로 존재하고 가운데(200)면은 Cu만 존재한다. 따라서 Au 층은 (100)면에서만 존재하여 각 Au층은 서로 0.5nm 떨어져 있다. 이와 같은 Cu3Au(100) 단결정을 MEIS(Medium Energy Ion Scattering Spectroscopy) 실험 장비를 사용하여 0.35nm 떨어져 있는 Single unit cell의 윗면과 아래면, 즉 첫 층의 Au와 셋째층의 Au의 층분리를 통해서, 온도 변화에 따른 Cu3Au(100) 단결정의 표면 물리적 현상인 surface induced disorder을 밝혀내고자 한다. 우선 두 Au층의 분리 시도는 수소이온을 이용한 실험 조건에서는 extremely glancing exit angle 등 극한의 산란조거에서도 성공하지 못하였다. 깊이 분해능을 정해주는 electronic energy loss를 극대화하기 위해 수소이온이 아닌 질소 이온을 사용하여 energy spectra를 측정해 본 결과 아래 그림에서와 같이 표면 Au 층과 표면 셋째 Au층을 구분할 수 있었다. <110>으로 align된 조건에서는 셋째층의 Au 원자들이 완전히 shadow cone 내부에 존재하여 관측되지 않지만 9.75$^{\circ}$ tilt 한 경우 셋째층의 Au 원자들이 shadow cone 바깥으로 나오게 되어 그림에서와 같이 첫째 층과 셋째 층이 확실히 분리되어 측정되었다. 이를 바탕을 Cu3Au(100)의 온도변화에 다른 order disorder and segregation 현상을 측정하였다. ordered Cu3Au(100)은 28$0^{\circ}C$ 근처에서 surface층이 먼저 disordered상으로 바뀌는 surface induced disorder 현상이 일어나고 bulk transition 온도 39$0^{\circ}C$ 이하에서 R.T으로 온도를 낮추면 본래의 ordered 구조로 되돌아간다. 하지만 bulk transition 온도를 지나면 order-disorder transition이 비가역적이고 segregation 현상이 일어난다.