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Immune-Enhancing Effects of Phellinus linteus Fruit Body and Mycelium Cultured in Cudrania tricuspidata (꾸지뽕나무 배양 상황버섯 자실체 및 균사체의 면역증진 효과)

  • Hong, Da Hyun;Joo, In Hwan;Park, Jong Min;Han, Su Hyun;Lee, Su Bin;Gwak, Seong Geun;Kim, Dong Hee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.33 no.5
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    • pp.275-281
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    • 2019
  • Polysaccharides produced in microorganisms and plants are known to increase the immune response in the body. We proposed analysis of beta-glucan contents of phellinus linteus fruit body (FB) and mycelium (MC) cultured in cudrania tricuspidata. Also, we examined whether fruit body and mycelium can increase the immune response in cyclophosphamide-induced immunosuppression animal models. We injected cyclophosphamide (50 mg/kg) twice to produce immunosuppression mice. Then, FB (200 mg/kg) and MC (200 mg/kg) were oral administered for 14 days. In order to confirm the immune-enhancing effect of FB and MC, we analyzed spleen weight, the number of immune cells, cytokines, and immunoglobulins levels. Cyclophosphamide decreased the weight of spleen, the number of immune cells. However, FB and MC have significantly increased the weight of spleen, the number of white blood cell, lymphocyte and monocyte. In addition, they have significantly increased immune-related cytokines (IL-2 and IFN-${\gamma}$) and immunoglobulins (IgA, IgG, IgM) levels. As a results, phellinus linteus fruit body (FB) and mycelium (MC) cultured in cudrania tricuspidata can be used as effective natural materials for immune-enhancing.

A study on proportional multiple-resonance controller for harmonic distortion compensation of single phase VSIs (단상 전압 소스 인버터의 고조파 왜곡 보상을 위한 비례 다중 공진 제어기에 관한 연구)

  • Bongwoo Kwak
    • Journal of IKEEE
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    • v.27 no.3
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    • pp.319-326
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    • 2023
  • In this paper, simulation and experimental results are presented, including the implementation of a digital controller for robust output voltage control of a single-phase voltage source inverters (VSIs) and total harmonic distortion (T.H.D.v) analysis. Typically, the VSIs uses a proportional integral (PI) controller for the current controller on the inner loop and a proportional resonant (PR) controller for the voltage controller on the outer loop to control the output voltage. However, non-linear loads still produce high-order odd harmonic distortion. Therefore, in this paper, a proportional multiple resonance (PMR) controller with a resonance controller for odd harmonic frequencies is proposed to suppress harmonic distortion. Analyze the frequency response of controllers for VSI plants and design PMR controllers. Through simulation, the total harmonic distortion characteristics of the output voltage are compared and verified when PI and PMR are used as voltage controllers. Both linear and non-linear loading conditions were considered. Finally, the effectiveness of the PMR controller was demonstrated by applying it to a 3kW VSIs prototype.

Effect of digital noise reduction on the accuracy of endodontic file length determination

  • Mehdizadeh, Mojdeh;Khademi, Abbas Ali;Shokraneh, Ali;Farhadi, Nastaran
    • Imaging Science in Dentistry
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    • v.43 no.3
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    • pp.185-190
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    • 2013
  • Purpose: The aim of the present study was to evaluate the measurement accuracy of endodontic file length on periapical digital radiography after application of noise reduction digital enhancement. Materials and Methods: Thirty-five human single-rooted permanent teeth with canals measuring 20-24 mm in length were selected. ISO #08 endodontic files were placed in the root canals of the teeth. The file lengths were measured with a digital caliper as the standard value. Standard periapical digital images were obtained using the Digora digital radiographic system and a dental X-ray unit. In order to produce the enhanced images, the noise reduction option was applied. Two blinded radiologists measured the file lengths on the original and enhanced images. The measurements were compared by repeated measures ANOVA and the Bonferroni test (${\alpha}=0.05$). Results: Both the original and enhanced digital images provided significantly longer measurements compared with the standard value (P<0.05). There were no significant differences between the measurement accuracy of the original and enhanced images (P>0.05). Conclusion: Noise reduction digital enhancement did not influence the measurement accuracy of the length of the thin endodontic files on the digital periapical radiographs despite the fact that noise reduction could result in the elimination of fine details of the images.

Effects of Laser Source Geometry on Laser Shock Peening Residual Stress (레이저 광원 형상이 레이저 충격 피닝 잔류응력에 미치는 영향)

  • Kim, Ju-Hee;Kim, Yun-Jae;Kim, Joung-Soo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.36 no.6
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    • pp.609-615
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    • 2012
  • In LSP (laser shock peening) treatment, the laser source geometries when the laser beam strikes the metal target area are diverse. The laser spot geometry affects the residual stress field beneath the treated surface of the metallic materials, which determines the characteristics of the pressure pulse. In this paper, detailed finite-element (FE) simulations on laser shock peening have been conducted in order to predict the magnitude and of the residual stresses and the depth affected in Inconel alloy 600 steel. The residual stress results are compared for circular, rectangular, and elliptical laser spot geometries. It is found that a circular spot can produce the maximum compressive residual stresses near the surface but generates tensile residual stresses at the center of the laser spot. In the depth direction, an elliptical laser spot produces the maximum compressive residual stresses. Circular and elliptical spots plastically affect the alloy to higher depths than a rectangular spot.

Quality of Life and Nutritional Outcomes of Billroth I and Billroth II Reconstruction (위 아전절제술 후 소화관 재건 방법에 따른 영양상태와 삶의 질의 비교)

  • Yu, Wan-Sik;Chung, Ho-Young
    • Journal of Gastric Cancer
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    • v.2 no.2
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    • pp.91-95
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    • 2002
  • Purpose: We compared the quality of life (QOL) and nutritional outcomes following both Billroth I (BI) and Billroth II (BII) reconstructions after a subtotal gastrectomy in order to identify which reconstruction would produce a better QOL and nutritional outcomes and to provide better follow-up management. Materials and Methods: We studied 273 patients without evidence of recurrent disease following a curative distal subtotal gastrectomy for gastric cancer. Among them, 135 underwent a BI reconstruction and 138 a BII reconstruction. The nutritional status was assessed by using levels of hemoglobin, serum albumin, iron, and vitamin B12 and by calculating the relative body weight, the body mass index, and the percentage of body fat. The QOL was measured by using the Troidl score and by treatment-specific symptoms based on the criteria, somewhat modified by the authors, of Korenaga and others. Results: There was no significant difference in QOL between the BI and the BII groups. More than half of the patients revealed anemia, regardless of the type of reconstruction. The serum vitamin $B_{12}$ level of the BII group was lower than that of the BI group. The BII group showed a tendency toward lower hemoglobin levels and serum iron concentrations than the BI group did. Conclusions: The quality of life was not impaired in most patients after either a BI or a BII reconstruction. However, both resulted in iron deficiency anemia, although the incidence was higher after a BII reconstruction. The patient's serum iron and vitamin B12 should be measured periodically and these must be administered if the measurements reveal a below normal range.

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Fabrication and Evaluation of Integrated Composite Part for Aircraft using OoA (Out-of-Autoclave) Prepreg (OoA (Out-of-Autoclave) 프리프레그를 이용한 항공기용 복합재 일체형 부품 제작 및 평가)

  • Hong, Sungjin;Song, Min-Hwan;Song, Keunil;Baik, Sang-Moon;Shin, Sang-Jun
    • Composites Research
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    • v.29 no.5
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    • pp.315-320
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    • 2016
  • Conventionally, composite aircraft structures are fabricated within autoclave at high pressure. However, autoclave process has several disadvantages including high curing costs and limitation of part size. Recently, out-of-autoclave (OoA) processes have been investigated in many studies to replace conventional autoclave process. A newly developed OoA prepreg, using conventional ovens, can significantly reduce the curing costs and produce autoclave-quality parts. Nevertheless, manufacture of void-free complex shape structure using OoA process presents significant challenges because of the low consolidation pressure. In this study, integrated skin-spar-rib composite part was fabricated using OoA prepreg. And cross-sectional macro- and micro-graphs of the part were examined in order to assess the possibility of replacing conventional autoclave process.

Active Earth Pressure behind Rigid Retaining Wall Rotating about the Base (저점을 중심으로 회전하는 강성옹벽에 작용하는 주동토압)

  • 백규호
    • Journal of the Korean Geotechnical Society
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    • v.20 no.8
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    • pp.193-203
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    • 2004
  • Arching effects in backfill materials generate a nonlinear active earth pressure distribution on a rigid retaining wall with rough face, and arching effects on the shape of the nonlinear earth pressure distribution depends on the mode of wall movement. Therefore, the practical shape of failure surface and arching effect in the backfill changed with the mode of wall movement must be considered to calculate accurate magnitude and distribution of active earth pressure on the rigid wall. In this study, a new formulation for calculating the active earth pressure on a rough rigid retaining wall rotating about the base is proposed by considering the shape of nonlinear failure surface and arching effects in the backfill. In order to avoid mathematical complexities in the calculation of active earth pressure, the imaginary failure surface composed of four linear surfaces is used instead of the nonlinear failure surface as failure surface of backfills. The comparisons between predictions from the proposed equations and existing model test results show that the proposed equations produce satisfactory predictions.

A Study on Viewers' Subjective Perception of Food TV Program -Focus on Program Planning Intentions- (음식 TV 프로그램에 대한 시청자들의 주관성 연구 -프로그램 기획의도를 중심으로-)

  • Yoon, Sun-Min;Hong, Jang-Sun;Kim, Myung-Hee
    • The Journal of the Korea Contents Association
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    • v.18 no.1
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    • pp.651-664
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    • 2018
  • With the rising popularity of food shows driven by the development of information and communication technologies, food-incorporated broadcasting programs based on various materials are produced in large numbers. This situation has raised a need for each program to examine viewers' preference factors for planning intentions in order to produce competitive programs. This study thus examined viewers' preference factors for food programs and planning intentions and discovered total three factors. The first factor places importance on practicality and entertainment and enjoys food and food programs as a means of resting. The second factor searches for specialized information and focuses on the essential meanings of food and the delivery of the right information. Finally, The third factor gets satisfaction from interactions with food programs and finds joy in storytelling and communication provided by broadcasting programs. These factors have different tendencies from one another, and the present study proposed a concept design for food broadcasting programs based on them.

Form Manufacturing and Quality Characteristics using Extracts from Hericium erinaceus (노루궁뎅이버섯 추출물을 이용한 제형가공 및 품질특성)

  • Park, Su-Jung;Hong, Joo-Heon;Youn, Kwang-Sup;Choi, Yong-Hee
    • Food Science and Preservation
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    • v.13 no.5
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    • pp.569-573
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    • 2006
  • This study was conducted to manufacture new product containing high soluble polysaccharide from Hericium erinaceus extract. The new products were prepared for powder, granulate and tablet form by spray drying process. The high soluble powder form was mixed with sub-ingredients and then granulated form by granulator and molded as tablet form by a press molder respectively. Moisture content of products was following order; spray dried powder > granule > tablet Total sugar content of produce was observed to 19.14% in spray dried powder, 37.58% in granulate and 35.76% in tablet. The hue angle of products was $85.5^{\circ}$ in spray dried powder, $95.37^{\circ}$ in granulate and $94.67^{\circ}$ in tablet. The absorption capacity was higher in powder, but the product type did not affect the color.

Assembly Neutron Moderation System for BNCT Based on a 252Cf Neutron Source

  • Gheisari, Rouhollah;Mohammadi, Habib
    • Progress in Medical Physics
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    • v.29 no.4
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    • pp.101-105
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    • 2018
  • In this paper, a neutron moderation system for boron neutron capture therapy (BNCT) based on a $^{252}Cf$ neutron source is proposed. Different materials have been studied in order to produce a high percentage of epithermal neutrons. A moderator with a construction mixture of $AlF_3$ and Al, three reflectors of $Al_2O_3$, BeO, graphite, and seven filters (Bi, Cu, Fe, Pb, Ti, a two-layer filter of Ti+Bi, and a two-layer filter of Ti+Pb) is considered. The MCNPX simulation code has been used to calculate the neutron and gamma flux at the output window of the neutronic system. The results show that the epithermal neutron flux is relatively high for four filters: Ti+Pb, Ti+Bi, Bi, and Ti. However, a layer of Ti cannot reduce the contribution of ${\gamma}$-rays at the output window. Although the neutron spectra filtered by the Ti+Bi and Ti+Pb overlap, a large fraction of neutrons (74.95%) has epithermal energy when the Ti+Pb is used as a filter. However, the percentages of the fast and thermal neutrons are 25% and 0.5%, respectively. The Bi layer provides a relatively low epithermal neutron flux. Moreover, an assembly configuration of 30% $AlF_3+70%$ Al moderator/$Al_2O_3$ reflector/a two-layer filter of Ti+Pb reduces the fast neutron flux at the output port much more than other assembly combinations. In comparison with a recent model suggested by Ghassoun et al., the proposed neutron moderation system provides a higher epithermal flux with a relatively low contamination of gamma rays.