• Journal of Yeungnam Medical Science
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• 제13권2호
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• pp.308-323
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• 1996

저자는 설문지 방식에 의해 1995년 8월1일부터 1995년 11월 30일까지 서울에 직장을 갖고 있는 직장인 282명을 대상으로 그들이 작성한 설문지를 분석하여 측두하악장애의 분포 및 관련요인과의 상관관계에 대해 다음과 같은 결론을 얻었다. 1. 측두하악장애의 증상을 가진 사람이 남자 41.88%, 여자 46.15%로 전체의 43.26%였다. 2. 일반관절 및 근육통의 증상이 심할수록, 두통 및 진통제 복용빈도가 높을수록, 측두하악장애증상의 빈도가 높았으며 이들 사이에 매우 유의한 상관이 있었다(p<0.001). 3. 이갈이, 이악물기, 구강악습관의 빈도가 높을수록 측두하악장애 증상의 빈도가 높았으며 Stress에 예민하게 반응할수록 이갈이나 이악물기, 깨무는 습관 등 이상기능 빈도가 높게 나타났다. 4. 편측저작이 양측저작에 비해 측두하악장애지수가 높게 나타났으며 통증부위와 측두하악장애 지수와의 연관성은 나타나지 않았다.

• Imaging Science in Dentistry
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• 제44권1호
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• pp.7-13
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• 2014

Purpose: This study was performed to evaluate the prevalence of all types and subtypes of dental anomalies among 7- to 35-year-old patients by using panoramic radiographs. Materials and Methods: This cross-sectional study was conducted on 1649 people in Hamadan City, in 2012-2013. The prevalence of four types and 12 subtypes of dental anomalies was evaluated by two observers separately by using panoramic radiography. Dental anomalies were divided into four types: (a) shape (including fusion, taurodontism, and dens invagination); (b) number (including hypodontia, oligodontia, and hyperdontia); (c) structure (including amelogenesis imperfecta, dentinogenesis imperfecta, and dentin dysplasia); and (d) position (including displacement, impaction, and dilacerations). Results: The reliability between the two observers was 79.56% according to the Kappa statistics. The prevalence of dental anomalies diagnosed by panoramic radiographs was 29%. Anomalies of position and number were the most common types of abnormalities, and anomalies of shape and structure were the least in both genders. Anomalies of impaction (44.76%), dilacerations (21.11%), hypodontia (15.88%), taurodontism (9.29%), and hyperdontia (6.76%) were the most common subtypes of dental anomalies. The anomalies of shape and number were more common in the age groups of 7-12 years and 13-15 years, respectively, while the anomalies of structure and position were more common among the other age groups. Conclusion: Anomalies of tooth position were the most common type of dental anomalies, and structure anomalies were the least in this Iranian population. The frequency and type of dental anomalies vary within and between populations, confirming the role of racial factors in the prevalence of dental anomalies.

• 한국임상수의학회지
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• 제26권6호
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• pp.612-615
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• 2009

10년령의 수컷 잡종견이 3개월 간의 구강내 궤양성 종양을 주증으로 내원하였다. 신체검사상 오른쪽 상악 잇몸에서 돌출된 구강내 종양이 관찰되었다. 내원당시 전이소견은 관찰되지 않았으며 구강 종양의 절제생검을 통한 조직검사결과 전반적인 상피양 세포와 일부 방추세포를 가진 전형적인 신경내분비종으로 의심되는 소견이 관찰되었다. 멜라닌 과립으로 추정되는 소견은 관찰되지 않았지만 악성종양에서 관찰되는 세포의 유사분열은 다수 관찰되었다. 확진을 위해 조직 절제 단면에 Melan A를 이용한 면역화학조직 염색을 실시하였으며, 그 결과는 강한 양성반응을 나타내었다. 조직검사와 조직면역염색을 통하여 종양은 멜라닌 결핍 악성흑색종으로 진단되었다. 결론적으로 본 증례의 경우 개에서 멜라닌결핍 악성흑색종의 진단에 Melan A를 이용한 면역화학조직염색이 유용함을 보여준다고 생각된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제46권3호
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• pp.183-190
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• 2020

Objectives: The purpose of this retrospective epidemiological study was to determine the etiology and pattern of maxillofacial injuries in a pediatric population. Materials and Methods: Data for pediatric maxillofacial trauma patients aged 12 years and younger who were registered at the Department of Pediatric and Preventive Dentistry, Dr. R. Ahmed Dental College and Hospital, Kolkata, India, were reviewed and examined. Patients who were treated between October 2016 and September 2018 were analyzed according to age, sex, cause of injury, frequency and site of facial fractures, and soft tissue injuries. The chi-square tests were carried out for statistical analyses with a significance level of 5%. Results: Of 232 patients with a mean age of 6.77±3.25 years, there were 134 males (57.8%) and 98 females (42.2%). The overall male to female ratio was 1.39:1. The most common causes of injuries were falls (56.5%) and motor vehicle accidents (16.8%). Incidence of falls decreased significantly with age (P<0.001). Dentoalveolar injuries (61.6%) and soft tissue injuries (57.3%) were more common than facial fractures (42.7%). Mandibular fractures (82.8%) were the most common facial fractures, and perioral or lip injuries were the most prevalent injuries in our patient population. There was a positive association between facial fractures and soft tissue injury (P<0.01) (odds ratio 0.26; confidence interval 0.15-0.46). Conclusion: Falls were the leading cause of maxillofacial trauma in our sample of children, and the most common site of fractures was the mandible.

• Journal of Preventive Medicine and Public Health
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• 제29권3호
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• pp.483-494
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• 1996

The objectives of this study are to estimate the prevalence of diabetes mellitus (DM) and to identify risk factors associated with fasting blood sugar in a rural adult population. We carried out a cross - sectional study on the residents over 30-year old. Among the 1077 eligible subjects, 725 persons responded to the study;the study consisted of interview on family and past history of DM, anthropometry, blood pressure, and blood sugar level in each subjects. Only 707 subjects of 725 participants had fasting blood sugar(FBS) examined and the rest, 18 subjects were had casual blood sugar examined due to failure of fasting over 8 - hour. When subjects had $FBS\geq140mg/dl$, 2 hours postprandial blood sugar level was checked after 75g oral glucose loading. The prevalence of DM was 8.9%, and age standarized prevalence rate adjusted to Korean population of 1995 was 5.8%. Mean and SD of fasting blood sugar in men was $99.8{\pm}22.6$, and in women was $111.5{\pm}29.9$. Mean levels of fasting blood sugar were significantly higher in women than in man and as their ages advanced the prevalences increased in both sexes. PP2 blood sugar levels were significantly higher in elder age and in persons with higher FBS levels than others. The risk factors associated with FBS were past history of diabetes, sex, socioeconomic status and waist - to - hip circumference ratio;the risk of diabetes was increased in female, people with past DM history, central obesity and low socioeconomic state. The low socioeconomic status associated with DM in this study, which is different from other study results, should be pursued in further studies.

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.1277-1280
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• 2015

Aim: To report epidemiologic and anatomoclinical transitions of inflammatory breast cancer (IBC) in Tunisia. Materials and Methods: Data including clinico-pathological data for 208 cases of T4d or PEV 3 non-metastatic breast cancer diagnosed between 2005 and 2010 were collected from patient records. Chi2 and Z tests were used to compare variables with two Tunisian historical series and a series about Arab-American patients. Results: Thirty three percent of our patients had their first child before 23 years of age and 56% had their menarche before 12 years, 75% never receiving oral contraception. Obesity was observed in 42% of women and IBC occurred during pregnancy in 13% of cases. Tumor grade was II-III in 90% of cases, HR was negative in 52%, HER2 was over expressed in 31% and invasion of more than 3 axillary nodes occurred in 18% of patients. We observed a pCR rate of 19% after neoadjuvant treatment (anthracyline-taxane used in 79%, trastuzumab in 27% ). Compared to historical Tunisian series (since 1996), IBC epidemiology remained stable in terms of median age, menopausal status and obesity. However we observed a significant decrease in median clinical tumor size and number of positive axillary lymph nodes. Comparison to IBC in Arab-Americans showed a significant difference in terms of median age, menopausal status, positivity of hormonal receptors and educational level. Conclusions: Our assessment of epidemiologic transition showed a reduction of clinco-pathological stage of IBC, keeping the same characteristics as compared to Tunisian historical series over a period of 14 years. Features seem to be different in Arab-American patients, probably related to migration, "occidentalization" of life style and improvement in socio-economic level.

• Journal of Oral Medicine and Pain
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• 제31권1호
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• pp.101-111
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• 2006

측두하악관절장애에 관한 역학연구는 주로 1970년대 초 스칸디나비아국가에서 국민을 대상으로 무작위 추출법에 의한 악관절 및 저작계기능에 관한 역학조사로 시작되었으며 국내에서도 1970년대 이후 측두하악관절장애의 유병률에 대해 많은 역학연구가 보고되었다. 하지만 성, 병력, 주소, 진단에 따른 각각의 증상과 징후들을 평가한 연구는 외국에 비해서 많이 부족한 실정이다. 측두하악관절장애에 대한 증상과 진단에 관한 총괄적 연구조사는 오래전에 이루어진 것이 대부분이기 때문에 본 연구를 통해서 측두하악관절장애를 가진 환자들의 성, 병력, 주소, 진단에 따른 증상들을 총괄적으로 조사하여 향후 점증하는 측두하악관절장애환자의 진단과 치료에 도움이 되는 기초자료를 확보하고자 하였다. 본 연구결과를 보면 우선 연령의 경우 전체 내원 환자 6500명의 평균나이는 34.06세로 남자는 33.15세, 여자는 34.62세였으며 진단그룹별로 연령차이가 있었다. 의뢰 환자는 대체로 치과의사가 의뢰한 환자가 많았으며(80.07%), 의뢰한 환자 진단군은 관절성장애, 근육성장애, 연조직질환 순이었다. 전체 내원 환자 중 63%가 안면통증으로 내원하였으며, 발생부위에 대한 비교에서 좌우 유의한 차이를 볼 수 없었다. 또한 통증 발생은 6개월 미만에서는 주로 남성이, 6개월 이상인 경우는 여성의 비율이 상대적으로 높음을 알 수 있었다. 관절잡음의 경우 병력 환자는 3445명(53.15%)였으며, 발병시기에는 성차가 없었다. 관절잡음의 발생부위는 좌우 양측간에 차이가 없었으며 주로 clicking sound가 많음을 알 수 있었다. 이갈이는 주로 남자에서, 이악물기는 여자에서 나타났었다.

• 치위생과학회지
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• 제12권5호
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• pp.451-458
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• 2012

기존 문헌의 조사결과 우리나라의 경우 전체 암에 대한 구강암 발생률은 감소하고 있지만 발생자수는 해마다 증가하고 있었다. 외국의 경우도 발생자수는 증가하고 있고, 반면 치사율은 낮아지고 있었다. 인구학적 특성에 따라서는 전반적으로 남자가 여자보다 구강암 발생률이 높았으며, 특히 연령이 낮을수록 남자와 여자의 발생 비율의 차이가 현저히 남자가 높았다. 구강암은 연령이 높은 집단에서 발생률이 증가하였다. 연령이 높을수록 협점막에서, 연령이 낮을수록 혀에서 다발하는 것으로 보고되었으나, 전반적으로 구내암이 가장 많이 빈발하였다. 구강암의 원인을 살펴본 많은 연구에서 담배와 음주를 구강암 발생의 원인으로 꼽았다. 특히 담배와 흡연은 구강암뿐만 아니라 기타 여러 암에 영향을 미친다. 따라서 구강암을 비롯한 여러 암발생을 감소시키기 위해 제도적, 행정적, 법적으로 적극적인 금연정책이 필요하며 더불어 절주 또는 금주에 대한 홍보가 필요할 것이다. 또한 구강암의 위험요인은 국가 및 지역별, 인구학적 특성에 따른다. 즉 태양으로부터 노출된 자외선의 양이 많을수록 입술 암이 발생하는 것과 낮은 경제적 수준과 교육수준, 힘겹게 연명하는 정도의 삶의 수준은 구강암을 발생에 영향을 주게 된다. 이외에도 비타민 및 단백질 결핍과 같은 영양결핍, 구강위생정도 및 인식과 습관 등도 구강암을 발생시킨다. 따라서 사회경제적 수준에 따른 격차가 생기지 않도록 국가 내에서, 또한 국가간의 사회적 불균형의 해소가 중요하다. 암은 점점 생존율이 높아지고 있지만 아직까지 현대 질병의 사망원인으로 큰 비중을 차지하고 있으며, 계속해서 이환된 환자가 증가하고 있다. 구강암은 기타 암 발생비율에 비해 낮아지는 수치를 보이고 있지만 발생자수가 증가하고 있어 구강암 발생 동향을 파악하고 인구학적 특성과 관련된 연구가 지속적으로 시행되어야 한다. 또한 구강암과 관련된 조직학적 연구나 현재 동향의 정보는 구강암 생존과 관련된 여러 요인을 파악하는데 도움을 주며, 구강암에 관한 계속적인 연구는 효과적인 구강건강프로그램을 개선시키고 구강보건교육과 구강암 검사프로그램을 만드는데 자료로 제공될 수 있다. 이제 암의 재발기간이 5년에서 10년으로 늘어난 만큼 암은 정복 되어야 할 질병으로 구강암 발생을 줄이기 위해서는 조기진단과 공중구강보건교육 및 예방정책이 필요하다. 따라서 정부와 관련된 단체 및 3차 진료기관 등과 협력하여 치과계 직종 종사자들은 책임감을 갖고 국민의 구강건강상태를 향상시키고 구강암 발생을 감소시키는데 노력해야 할 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6059-6062
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• 2012

Regional cancer epidemiology is an important basis for determining the priorities for cancer control in different countries worldwide. There is no reliable information about the pattern of head and neck cancer in western Nepal and hence an attempt was here made to evaluate the situation based on hospital data, which provide the only source in the western region of Nepal. A clinicopathological analysis of head and neck cancers treated between 2003 and 2006 in Manipal Teaching Hospital affiliated to Manipal College of Medical Sciences, Pokhara, Western Development Region, Nepal was performed. A total of 105 head and neck cancer cases were identified with a male to female ratio of 1.8:1. The median ages of male and female patients were 62 and 64 years, respectively. Ninety-seven (92.4%) of the cancer patients were suffering from carcinoma, three (2.9%) had blastoma, three (2.9%) had sarcoma, and two (1.9%) had lymphoma. The majority (61.9%) of carcinoma cases were squamous cell carcinoma followed by anaplastic carcinoma (7.2%). Of the carcinoma cases, the most common site of primary lesion was larynx (19.6%), followed by the thyroid (14.4%), the tongue and hypopharynx with 10.3% cases each. Comparative analysis among males and females did not reveal any sex difference in type of head and neck cancers. The head and neck cancer pattern revealed by the present study provides valuable leads to cancer epidemiology in western Nepal and useful information for health planning and cancer control, and future research in western Nepal.

• Imaging Science in Dentistry
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• 제48권1호
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• pp.11-19
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• 2018

Purpose: This study compared the diagnostic accuracy of cone-beam computed tomography (CBCT) scans obtained with 2 CBCT systems with high- and low-resolution modes for the detection of root perforations in endodontically treated mandibular molars. Materials and Methods: The root canals of 72 mandibular molars were cleaned and shaped. Perforations measuring 0.2, 0.3, and 0.4 mm in diameter were created at the furcation area of 48 roots, simulating strip perforations, or on the external surfaces of 48 roots, simulating root perforations. Forty-eight roots remained intact(control group). The roots were filled using gutta-percha (Gapadent, Tianjin, China) and AH26 sealer (Dentsply Maillefer, Ballaigues, Switzerland). The CBCT scans were obtained using the NewTom 3G (QR srl, Verona, Italy) and Cranex 3D (Soredex, Helsinki, Finland) CBCT systems in high- and low-resolution modes, and were evaluated by 2 observers. The chi-square test was used to assess the nominal variables. Results: In strip perforations, the accuracies of low- and high-resolution modes were 75% and 83% for NewTom 3G and 67% and 69% for Cranex 3D. In root perforations, the accuracies of low- and high-resolution modes were 79% and 83% for NewTom 3G and was 56% and 73% for Cranex 3D. Conclusion: The accuracy of the 2 CBCT systems was different for the detection of strip and root perforations. The Cranex 3D had non-significantly higher accuracy than the NewTom 3G. In both scanners, the high-resolution mode yielded significantly higher accuracy than the low-resolution mode. The diagnostic accuracy of CBCT scans was not affected by the perforation diameter.